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Immunohistochemical expression of types I and III collagen antibodies in the temporomandibular joint disc of human foetuses

L.O.C. de Moraes, F.R. Lodi, T. S. Gomes, C.T.F. Oshima, S.R. Marques, C.L.P. Lancellotti, J.F. Rodriguez-Vázquez, J.R. Mérida-Velasco, L.G. Alonso
  • F.R. Lodi
    Universidade Federal de São Paulo, Brazil
  • T. S. Gomes
    Universidade Federal de São Paulo, Brazil
  • C.T.F. Oshima
    Universidade Federal de São Paulo, Brazil
  • S.R. Marques
    Universidade Federal de São Paulo, Brazil
  • C.L.P. Lancellotti
    Santa Casa de São Paulo, Brazil
  • J.F. Rodriguez-Vázquez
    Universidad Complutense de Madrid, Spain
  • J.R. Mérida-Velasco
    Universidad Complutense de Madrid, Spain
  • L.G. Alonso
    Universidade Federal de São Paulo, Brazil

Abstract

The objective was to study the morphology of the articular disc and analyse the immunohistochemical expression of types I and III collagen markers in the temporomandibular joint (TMJ) disc of human foetuses of different gestational ages. Twenty TMJ from human foetuses supplied by Universidade Federal de Uberaba with gestational ages from 17 to 24 weeks were studied. The gestational age of the foetuses was determined by measuring the crown-rump (CR) length. Macroscopically, the foetuses were fixed in 10% formalin solution and dissected by removing the skin and subcutaneous tissue and exposing the deep structures. Immunohistochemical markers of type I and III were used to characterize the existence of collagen fibres. Analysis of the immunohistochemical markers of types I and III collagen revealed the presence of heterotypical fibril networks.

Keywords

articular disc; temporomandibular joint; human foetuses; collagen; immunohistochemical; embryology

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Submitted: 2011-02-07 20:28:31
Published: 2011-07-21 12:12:12
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Copyright (c) 2011 L.O.C. de Moraes, F.R. Lodi, T. S. Gomes, C.T.F. Oshima, S.R. Marques, C.L.P. Lancellotti, J.F. Rodriguez-Vázquez, J.R. Mérida-Velasco, L.G. Alonso

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