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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

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  • Tumor cells-derived exosomal PD-L1 promotes the growth and invasion of lung cancer cells in vitro via mediating macrophages M2 polarization

    Xiangjun Lu, Jian Shen, Siyuan Huang, Dongdong Liu, Haitao Wang
    01-08-2023
    https://doi.org/10.4081/ejh.2023.3784
    1558
    PDF: 721
    HTML: 15
  • Expression, localization and synthesis of small leucine-rich proteoglycans in developing mouse molar tooth germ

    Angammana Randilini, Kaoru Fujikawa, Shunichi Shibata
    10-02-2020
    https://doi.org/10.4081/ejh.2020.3092
    1419
    PDF: 1003
    HTML: 8
  • Impact of Histochemistry on biomedical research: looking through the articles published in a long-established histochemical journal

    C. Pellicciari
    30-12-2014
    https://doi.org/10.4081/ejh.2014.2474
    2041
    PDF: 634
    HTML: 804
  • The nucleus of differentiated root plant cells: modifications induced by arbuscular mycorrhizal fungi

    G Lingua, A Fusconi, G Berta
    9-20
    24-12-2009
    https://doi.org/10.4081/ejh.2001.1609
    820
    PDF: 971
  • The expression and the nuclear activity of the caretaker gene ku86 are modulated by somatostatin

    S Pucci, E Bonanno, F Pichiorri, P Mazzarelli, LG Spagnoli
    103-110
    29-06-2009
    https://doi.org/10.4081/873
    656
    PDF: 511
  • ASTROCYTE DYSFUNCTION IN AUTOSOMAL DOMINANT LEUKODYSTROPHY (ADLD): INSIGHTS FROM 2D AND 3D IN VITRO SYSTEMS AND EX VIVO CEREBROSPINAL FLUID METABOLOMICS F.D. Koufi1, V. Righi2, A. Mucci3, I. Rusciano1, S. Mongiorgi1, M. Shin4, Y. Kosodo4, I. Cani5, P. Cortelli6, E. Giorgio7, G. Ramazzotti1, L. Manzoli1, S. Ratti1 | 1 Cellular Signaling Laboratory, Anatomy Center, Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy; 2Department of Life Quality Studies, University of Bologna, Campus of Rimini, Rimini, Italy; 3Department of Geological and Chemical Sciences, University of Modena and Reggio Emilia, Modena, Italy; 4Korea Brain Research Institute (KBRI), Daegu, Republic of Korea; 5Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy; 6IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy; 7Department of Molecular Medicine, University of Pavia, Pavia, Italy; Medical Genetics Unit, IRCCS Mondino Foundation, Pavia, Italy.

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4312
    182
  • An ex vivo experimental system to track fluorescent nanoparticles inside skeletal muscle

    Laura Calderan, Flavia Carton, Ilaria Andreana, Valeria Bincoletto, Silvia Arpicco, Barbara Stella, Manuela Malatesta
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3596
    1011
    PDF: 553
    HTML: 31
  • Elastofibroma dorsi: a histochemical and immunohistochemical study

    A. Di Vito, E. Scali, G. Ferraro, C. Mignogna, I. Presta, C. Camastra, C. Palmieri, G. Donato, T. Barni
    19-02-2015
    https://doi.org/10.4081/ejh.2015.2459
    2462
    PDF: 800
    HTML: 1087
  • Biomolecular identification of (CCTG)n mutation in myotonic dystrophy type 2 (DM2) by FISH on muscle biopsy

    R Cardani, E Mancinelli, V Sansone, G Rotondo, G Meola
    437-442
    29-06-2009
    https://doi.org/10.4081/918
    937
    PDF: 727
  • BEYOND THE SPINAL CORD: MORPHOLOGICAL ALTERATIONS OF CORTICAL PROJECTION NEURON IN SPINAL MUSCULAR ATROPHY La Rocca F1,2, Schellino R1,2, Iezzi G1,2, Caretto A1,2, Boido B1,2 and Vercelli A1,2 | 1Department of Neuroscience “Rita Levi Montalcini”, University of Turin, Turin, Italy; 2Neuroscience Institute Cavalieri, Ottolenghi, University of Turin, Turin, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4495
    121
  • Low ozone concentrations do not exert cytoprotective effects on tamoxifen-treated breast cancer cells in vitro

    Chiara Rita Inguscio, Flavia Carton, Barbara Cisterna, Manuela Rizzi, Francesca Boccafoschi, Gabriele Tabaracci, Manuela Malatesta
    09-09-2024
    https://doi.org/10.4081/ejh.2024.4106
    1412
    PDF: 237
    HTML: 4
  • Cannabinoid CB2 receptors are involved in the protection of RAW264.7 macrophages against the oxidative stress: an in vitro study

    Sabrina Giacoppo, Agnese Gugliandolo, Oriana Trubiani, Federica Pollastro, Gianpaolo Grassi, Placido Bramanti, Emanuela Mazzon
    23-01-2017
    https://doi.org/10.4081/ejh.2017.2749
    5741
    PDF: 1260
    HTML: 386
  • Histochemistry in biology and medicine: a message from the citing journals

    Carlo Pellicciari
    23-12-2015
    https://doi.org/10.4081/ejh.2015.2610
    2876
    PDF: 820
    HTML: 882
  • Immunohistochemical evidence of Muc1 expression during rat embryonic development

    E. Lacunza, V. Ferretti, C. Barbeito, A. Segal-Eiras, M. V. Croce
    e49
    26-11-2010
    https://doi.org/10.4081/ejh.2010.e49
    1911
    PDF: 612
    HTML: 2291
  • Histomorphometric evaluation of intestinal cellular immune responses in pigs immunized with live oral F4ac+ non-enterotoxigenic E. coli vaccine against postweaning colibacillosis

    A. Kovšca Janjatovic, G. Lacković, F. Bozic, D. Kezic, M. Popovic, H. Valpotić, I. Harapin, Z. Pavicic, B. Njari, I. Valpotić
    e4
    11-02-2010
    https://doi.org/10.4081/ejh.2010.e4
    1586
    PDF: 830
    HTML: 1649
  • Topographic distribution pattern of morphologically different G cells in the murine antral mucosa

    Claudia Frick, Hanna Luisa Martin, Johanna Bruder, Kerstin Lang, Heinz Breer
    19-09-2017
    https://doi.org/10.4081/ejh.2017.2810
    1605
    PDF: 654
    HTML: 116
  • Immunohistochemical markers of CYP3A4 and CYP3A7: a new tool towards personalized pharmacotherapy of hepatocellular carcinoma

    D. Fanni, M. Manchia, F. Lai, C. Gerosa, R. Ambu, G. Faa
    11-04-2016
    https://doi.org/10.4081/ejh.2016.2614
    2181
    PDF: 757
    HTML: 412
  • Quantitative RT-PCR analysis and immunohistochemical localization of HSP70 in sea bass Dicentrarchus labraxexposed to transport stress

    C Poltronieri, L Maccatrozzo, C Simontacchi, D Bertotto, B Funkenstein, M Patruno, G Radaelli
    125-136
    10-08-2009
    https://doi.org/10.4081/1134
    790
    PDF: 1017
  • P49 | DEVELOPMENT OF AN INJECTABLE AND SELFASSEMBLING SCAFFOLD FOR THE DIRECT DELIVERY OF CARDIAC EXTRACELLULAR MATRIX AND CARDIAC PROGENITOR CELLS A. Menini1, V. Romano1, A. M. Sacco1, D. Nurzynska2, G. Ricci3, C. Amarelli4, C. Castaldo1, F. Di Meglio1 | 1Department of Public Health, University of Naples «Federico II», Naples, Italy; 2Department of Medicine, Surgery and Dentistry, University of Salerno, Baronissi; 3Department of Experimental Medicine, University of Campania «Luigi Vanvitelli», Naples, Italy; 4Department of Cardiac Surgery and Transplants, Monaldi Hospital, Naples, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4371
    183
  • Immunohistochemistry detected and localized cannabinoid receptor type 2 in bovine fetal pancreas at late gestation

    Cecilia Dall'Aglio, Angela Polisca, Maria Grazia Cappai, Francesca Mercati, Alessandro Troisi, Carolina Pirino, Paola Scocco, Margherita Maranesi
    07-03-2017
    https://doi.org/10.4081/ejh.2017.2761
    2330
    PDF: 946
    HTML: 318
  • Spatial expression of DNA topoisomerase I genes during cell proliferation in Daucus carota

    A Balestrazzi, G Bernacchia, L Pitto, G Luccarini, D Carbonera
    31-8
    24-12-2009
    https://doi.org/10.4081/ejh.2001.1611
    613
    PDF: 506
  • DNA damage in acute myeloid leukemia patients of Northern Mexico

    Martha I. Dávila-Rodríguez, Elva I. Cortés-Gutiérrez, Roberto Hernández-Valdés, Karla Guzmán-Cortés, Rosa E. De León-Cantú, Ricardo M. Cerda-Flores, Enrique Báez-De la Fuente
    11-12-2017
    https://doi.org/10.4081/ejh.2017.2851
    1512
    PDF: 515
    HTML: 135
  • An ex vivo study on immunohistochemical localization of MMP-7 and MMP-9 in temporomandibular joint discs with internal derangement

    C. Loreto, R. Leonardi, G. Musumeci, G. Pannone, S. Castorina
    e12
    15-04-2013
    https://doi.org/10.4081/ejh.2013.e12
    2534
    PDF: 768
    HTML: 423
  • Restorative effects of camellia oil on the skin-barrier function in a model of DNCB-induced atopic dermatitis

    Shicheng Jiao, Lijun Deng, Mu Niu, Jie Yang
    21-01-2025
    https://doi.org/10.4081/ejh.2025.4147
    2609
    PDF: 576
    HTML: 36
  • Expression and role of cocaine-amphetamine regulated transcript (CART) in the proliferation of biliary epithelium

    Arianna Casini, Giorgio Vivacqua, Rosa Vaccaro, Anastasia Renzi, Stefano Leone, Luigi Pannarale, Antonio Franchitto, Paolo Onori, Romina Mancinelli, Eugenio Gaudio
    19-10-2023
    https://doi.org/10.4081/ejh.2023.3846
    1515
    PDF: 570
    HTML: 15
  • Sufentanil alleviates cerebral ischemia-reperfusion injury by inhibiting inflammation and protecting the blood-brain barrier in rats

    Zhen Wang, Xiaoyan Du, Daoyang Yu, Yang Yang, Gaoen Ma, Xueli Jia, Lulu Cheng
    12-01-2022
    https://doi.org/10.4081/ejh.2022.3328
    1928
    PDF: 1076
    HTML: 77
  • Ontogenic development of corticotrophs in fetal buffalo (Bubalus bubalis) pituitary gland

    M. A. Sandhu, A. A. Saeed, M. S. Khilji, R. H. Pasha, N. Mukhtar, M. S. Anjum
    30-01-2014
    https://doi.org/10.4081/ejh.2014.2292
    3254
    PDF: 632
    HTML: 623
  • Myosin Heavy Chain 2B isoform is expressed in specialized eye muscles but not in trunk and limb muscles of cattle

    L Maccatrozzo, M Patruno, L Toniolo, C Reggiani, F Mascarello
    357-366
    29-06-2009
    https://doi.org/10.4081/908
    626
    PDF: 485
  • MITOCHONDRIAL DYSFUNCTION AS A KEY FACTOR OF MOTOR NEURON DEGENERATION: INSIGHTS FROM AMYOTROPHIC LATERAL SCLEROSIS CELLULAR MODELS Scimia N¹, Carletti RM², Rasà MD¹, Ferrari D3, Boido M¹ and Stanga S¹ | ¹Neuroscience Institute Cavalieri Ottolenghi, Orbassano (TO), Department of Neuroscience Rita Levi Montalcini, University of Turin, Italy; ²Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy; 3Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4512
    125
  • 2D vs 3D morphological analysis of dorsal root ganglia in health and painful neuropathy

    Valentina Alda Carozzi, Chiara Salio, Virginia Rodriguez-Menendez, Elisa Ciglieri, Francesco Ferrini
    19-10-2021
    https://doi.org/10.4081/ejh.2021.3276
    2645
    PDF: 1513
    Video 1: 208
    Video 2: 231
    HTML: 18
  • The knee joint loose body as a source of viable autologous human chondrocytes

    J. Melrose
    10-06-2016
    https://doi.org/10.4081/ejh.2016.2645
    2112
    PDF: 686
    HTML: 393
  • Receptor-mediated endocytosis of lysozyme in renal proximal tubules of the frog Rana temporaria

    E.V. Seliverstova, N.P. Prutskova
    13-04-2015
    https://doi.org/10.4081/ejh.2015.2482
    2288
    PDF: 755
    HTML: 1129
  • P53 | CIRCADIAN DEPENDENT MOTILITY: THE ROLE FOR THE PERINUCLEAR ACTIN CAP E. Montacci1, M. Sgarzi2, L. Dall’Olio3, E. Giampieri4, D. Romaniello4, M. Lauriola5 | 1Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy; 2IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; 3Laboratory of Data Science and Bioinformatics, IRCSS Institute of Neurological Sciences, Bellaria Hospital, Bologna, Italy; 4Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy; 5Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4375
    165
  • Distribution of alpha-synuclein in normal human jejunum and its relations with the chemosensory and neuroendocrine system

    Arianna Casini, Romina Mancinelli, Caterina Loredana Mammola, Luigi Pannarale, Piero Chirletti, Paolo Onori, Rosa Vaccaro
    02-11-2021
    https://doi.org/10.4081/ejh.2021.3310
    2162
    PDF: 1064
    HTML: 58
  • Prognostic factors affecting disease-free survival rate following surgical resection of primary breast cancer

    K Horita, A Yamaguchi, K Hirose, M Ishida, S Noriki, Y Imamura, M Fukuda
    73-84
    24-12-2009
    https://doi.org/10.4081/ejh.2001.1616
    809
    PDF: 838
  • Endoplasmic reticulum stress contributed to inflammatory bowel disease by activating p38 MAPK pathway

    Yan Long, Yan Zhao, Xiaoqing Ma, Ya Zeng, Tian Hu, Weijie Wu, Chongtian Deng, Jinyue Hu, Yueming Shen
    23-05-2022
    https://doi.org/10.4081/ejh.2022.3415
    1886
    PDF: 1017
    HTML: 42
  • Neurodegeneration in zebrafish embryos and adults after cadmium exposure

    Antonio Monaco, Teresa Capriello, Maria C. Grimaldi, Valentina Schiano, Ida Ferrandino
    19-10-2017
    https://doi.org/10.4081/ejh.2017.2833
    2908
    PDF: 1154
    HTML: 143
  • Cartilage canals in newborn dogs: histochemical and immunohistochemical findings

    A. Di Giancamillo, M.E. Andreis, P. Taini, M.C. Veronesi, M. Di Giancamillo, S.C. Modina
    15-09-2016
    https://doi.org/10.4081/ejh.2016.2701
    1309
    PDF: 660
    Supplementary: 259
    HTML: 212
  • Expression of Ser729 phosphorylated PKCepsilon in experimental crescentic glomerulonephritis: an immunohistochemical study

    V.N. Karavana, H. Gakiopoulou, E.A. Lianos
    15-04-2014
    https://doi.org/10.4081/ejh.2014.2308
    1996
    PDF: 821
    HTML: 640
  • Drug delivery to the central nervous system

    Roberto Imberti, Alessandro Amatu
    16-09-2010
    https://doi.org/10.4081/1761
    711
    PDF: 398
    HTML: 195
  • P06 | MICROGRAVITY-INDUCED CHANGES IN CYTOSKELETON STRUCTURE OF TCAM-2 CELLS M. Berardini1, L. Gesualdi1, A. Di Pauli1, M. Signore2, S. Broccolucci1, F. Ferranti3, M. Bizzarri4, M. Tafani4, G. Ricci5, A. Catizone1 | 1Dept of Anatomy, Histology, Forensic-Medicine and Orthopedics,“Sapienza” University of Rome, Rome, Italy; 2RPPA Unit, Proteomics Area, Core Facilities, Istituto Superiore di Sanità, Rome, Italy; 3Human Spaceflight and Scientific Research Unit, Italian Space Agency, Rome, Italy; 4Dept of Experimental Medicine “Sapienza” University of Rome, Rome, Italy; 5Dept of Experimental Medicine, Università degli Studi della Campania “Luigi Vanvitelli”, Naples, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4326
    122
  • Adipose-derived stem cells promote the recovery of intestinal barrier function by inhibiting the p38 MAPK signaling pathway

    Mei Yang, Wangbin Xu, Chaofu Yue, Rong Li, Xian Huang, Yongjun Yan, Qinyong Yan, Shisheng Liu, Yuan Liu, Qiaolin Li
    21-01-2025
    https://doi.org/10.4081/ejh.2025.4158
    1373
    PDF: 435
    Supplementary Figure: 48
    HTML: 10
  • Management of autofluorescence in formaldehyde-fixed myocardium: choosing the right treatment

    Zhao Zhang, Hongming Fan, William Richardson, Bruce Z. Gao, Tong Ye
    02-10-2023
    https://doi.org/10.4081/ejh.2023.3812
    1505
    PDF: 802
    Supplementary: 103
    HTML: 21
  • Overexpression of hsa_circ_0006470 inhibits the malignant behavior of gastric cancer cells via regulation of miR-1234/TP53I11 axis

    Jinbi Xie, Yong Ning, Lihang Zhang, Yuan Lin, Runsheng Guo, Shanjuan Wang
    03-10-2022
    https://doi.org/10.4081/ejh.2022.3477
    1742
    PDF: 552
    HTML: 26
  • miR-126 targeting GOLPH3 inhibits the epithelial-mesenchymal transition of gastric cancer BGC-823 cells and reduces cell invasion

    Jiancai Ouyang, Fuhu Song, He Li, Rui Yang, Haicheng Huang
    28-10-2020
    https://doi.org/10.4081/ejh.2020.3168
    1205
    PDF: 560
    HTML: 19
  • Screening of histone deacetylases (HDAC) expression in human prostate cancer reveals distinct class I HDAC profiles between epithelial and stromal cells

    D Waltregny, B North, F Van Mellaert, J de Leval, E Verdin, V Castronovo
    273-290
    29-06-2009
    https://doi.org/10.4081/897
    951
    PDF: 1365
  • ALPHA SYNUCLEIN REGULATION IN BRAIN AND BONE MARROW IS RELETED TO THE DIFFERENTIAL EXPRESSION OF GATA1 TRANSCRIPTION FACTOR Velardi V1, Arciprete F1, Caturano C1, Rana RA1, Mancinelli R2, Zingariello M1 and Vivacqua G1 | 1Unit of Microscopic and Ultrastructural Anatomy, University Campus Bio-Medico, Rome, Italy; 2Department of Anatomic, Histologic, Forensic Medicine and Locomotor Apparatus Science, Sapienza University of Rome, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4515
    116
  • Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

    Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou
    06-08-2025
    https://doi.org/10.4081/ejh.2025.4228
    602
    PDF: 304
    HTML: 9
  • LncRNA FBXO18-AS promotes gastric cancer progression by TGF-β1/Smad signaling

    Yiming Zhang, Wanqiong Zheng, Liang Zhang, Yechun Gu, Lihe Zhu, Yingpeng Huang
    20-06-2023
    https://doi.org/10.4081/ejh.2023.3667
    976
    PDF: 528
    Supplementary: 75
    HTML: 13
  • Transmission electron microscopy for nanomedicine: novel applications for long-established techniques

    Manuela Malatesta
    09-12-2016
    https://doi.org/10.4081/ejh.2016.2751
    2108
    PDF: 1426
    HTML: 253
  • Effects of hyperthyroidism on expression of vascular endothelial growth factor (VEGF) and apoptosis in fetal adrenal glands

    T. Karaca, Y. Hulya Uz, R. Karabacak, I. Karaboga, S. Demirtas, A. Cagatay Cicek
    26-11-2015
    https://doi.org/10.4081/ejh.2015.2560
    2201
    PDF: 935
    HTML: 624
  • Syndecan expressions in the human amnion and chorionic plate

    T. Lorenzi, A. Turi, C. Crescimanno, M. Morroni, M. Castellucci, G. David, A. L. Tranquilli, D. Marzioni
    e42
    27-10-2010
    https://doi.org/10.4081/ejh.2010.e42
    1613
    PDF: 565
    HTML: 643
  • Distribution of NADPH-diaphorase and AChE activity in the anterior leaflet of rat mitral valve

    K. Lovasova, D. Kluchova, A. Bolekova, F. Dorko, T. Spakovska
    e5
    04-02-2010
    https://doi.org/10.4081/ejh.2010.e5
    1080
    PDF: 430
    HTML: 3066
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European Journal of Histochemistry

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