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• LABELING EXTRACELLULAR VESICLES FOR HIGHLY SENSITIVE FLOW CYTOMETRY ANALYSES P. Simeone^1,2, D. Brocco³, F. D’Ascanio^1,2,4, D. De Bellis^1,2, G. Colasante^1,2, A. Aquilini-Mummolo^1,2, T. Esmail^1,2, A. Younas², M. Filoso², C. Cichella², M. C. Cufaro⁵, A. Di Sebastiano⁵, D. Pieragostino⁶, S. Burattini⁷, M. Battistelli⁷, P. Del Boccio⁵, A. Fontana⁸, R. Di Pietro¹, P. Lanuti^1,2 | ¹Department of Medicine and Aging Sciences, University “G. d’Annunzio” of Chieti-Pescara, Italy; ²Flow Cytometry Core Facility, Center for Advanced Studies and Technology (CAST), University “G. d’Annunzio” of Chieti-Pescara, Italy; ³Department of Medical, Oral and Biotechnological Sciences, G. d’Annunzio University of Chieti-Pescara, Chieti, Italy; ⁴Department of Humanities, Law and Economics, Leonardo da Vinci University, Torrevecchia Teatina, Italy: ⁵Department of Science, University “G. d’Annunzio”, Chieti Pescara, Italy; ⁶Department of Innovative Technologies in Medicine and Dentistry, G. d’Annunzio University of Chieti-Pescara, Italy; ⁷Department of Biomolecular Sciences, University of Urbino, Urbino, Italy; ⁸Department of Pharmacy, University “G. d’Annunzio”, Chieti Pescara, Italy

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4302

  159

• FLOW CYTOMETRY IN THE DEVELOPMENT AND CHARACTERIZATION OF PRECLINICAL TUMOR MODELS BASED ON THE ANALYSIS OF EXTRACELLULAR VESICLES AS CANDIDATE LIQUID BIOMARKERS I. D’Agnano | Institute of Biomedical Technologies, CNR, Segrate, Milan, Italy

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4303

  149

• FLOW CYTOMETRY FOR THE ANALYSIS OF MICRO/ NANOPARTICLES: CURRENT APPLICATIONS AND CHALLENGES S. Amalfitano | National Research Council of Italy - Water Research Institute (CNR-IRSA) – Montelibretti, Rome, Italy

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4301

  170

• EXPRESSION OF PIEZO1 IN CLEAR CELL RENAL CELL CARCINOMA: INSIGHTS FROM BIOINFORMATIC AND IMMUNOHISTOCHEMICAL ANALYSES D. Jerka¹, P. Antosik², K. Bonowicz^1,3, D. Grzanka⁴, M. Gagat^1,3 | ¹Department of Histology and Embryology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Bydgoszcz, Poland; ²Department of Dermatology and Venerology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland; ³Faculty of Medicine, Collegium Medicum, Mazovian Academy in Płock, Płock, Poland; ⁴Department of Clinical Pathomorphology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4304

  178

• TRACKING HER2 TRAFFICKING AND ORGANELLE CROSSTALK IN TRASTUZUMAB-DERUXTECAN–TREATED BREAST CANCER CELLS USING MULTIMODAL IMAGING E. Tagliatti¹, M. C. Gagliani², G. Bellese², M. Crippa³, A. Abbona⁴, M. Paccagnella⁴, P. Arnaldi⁵, M. C. Merlano⁶, O. Garrone⁷, A.M. Porcelli⁸, M. Matteoli¹, P. Falletta⁹, P. Castagnola¹⁰, K. Cortese² | ¹IRCCS Humanitas Research Hospital, Laboratory of Pharmacology and Brain Pathology, Rozzano, Milano, Italy; ²DIMES, Department of Experimental Medicine, Cellular Electron Microscopy Lab, University of Genoa, Genoa, Italy; ³Experimental Imaging Center, IRCCS Ospedale San Raffaele, Milan, Italy; ⁴Health Department S. Croce e Carle Teaching Hospital, Cuneo, Italy; ⁵IRCCS Ospedale Policlinico San Martino, Genova, Italy; ⁶Scientific Direction, Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy; ⁷Medical Oncology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy; ⁸FABIT, Department of Pharmacy and Biotechnology and CIRI, Interdepartmental Centre for Industrial Research ‘Scienze Della Vita e Tecnologie per La Salute’, University of Bologna, Bologna, Italy; ⁹Vita-Salute San Raffaele University, Milan, Italy; ¹⁰IRCCS Ospedale Policlinico San Martino, Genova, Italy

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4305

  247