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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

1.9
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3.7
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1.9
Impact Factor 2025
3.7
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  • The Qi-Bang-Yi-Shen formula ameliorates renal dysfunction and fibrosis in rats with diabetic kidney disease via regulating PI3K/AKT, ERK and PPARγ signaling pathways

    Zhi Wang, Guihua Jian, Teng Chen, Yiping Chen, Junhui Li, Niansong Wang
    01-03-2023
    https://doi.org/10.4081/ejh.2023.3648
    5172
    PDF: 1195
    HTML: 48
  • Molecular characterization of nephron progenitors and their early epithelial derivative structures in the nephrogenic zone of the canine fetal kidney

    Rawah Faraj, Angela Irizarry-Alfonzo, Pawan Puri
    23-09-2019
    https://doi.org/10.4081/ejh.2019.3049
    1651
    PDF: 884
    HTML: 63
  • Independent and interactive roles of hirudin and HMGB1 interference in protecting renal function by regulating autophagy, apoptosis, and kidney injury in chronic kidney disease

    Ying Li, Xuan Gao, Yao Chen, Huihui Li, Jing Tang, Wei Sun
    07-04-2025
    https://doi.org/10.4081/ejh.2025.4182
    1310
    PDF: 787
    HTML: 51
  • Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

    Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou
    06-08-2025
    https://doi.org/10.4081/ejh.2025.4228
    1508
    PDF: 773
    HTML: 25
  • Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function

    Zhijiang Chen, Huili Wang, Bin Hu, Xinxin Chen, Meiyu Zheng, Lili Liang, Juanjuan Lyu, Qiyi Zeng
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3412
    2664
    PDF: 1508
    HTML: 38
  • Developmental immunolocalization of the Klotho protein in mouse kidney epithelial cells

    J.H. Song, M.Y. Lee, Y.J. Kim, S.R. Park, J. Kim, S.Y. Ryu, J.Y. Jung
    24-01-2014
    https://doi.org/10.4081/ejh.2014.2256
    3856
    PDF: 981
    HTML: 513
  • Combination of tolvaptan and valsartan improves cardiac and renal functions in doxorubicin-induced heart failure in mice

    Fengqin Yan, Hong Zhu, Yingxia He, Qinqin Wu, Xiaoyu Duan
    11-11-2022
    https://doi.org/10.4081/ejh.2022.3563
    1907
    PDF: 939
    Supplementary: 155
    HTML: 39
  • Emodin improves renal fibrosis in chronic kidney disease by regulating mitochondrial homeostasis through the mediation of peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC-1α)

    Liuchang Feng, Zaoqiang Lin, Zeyong Tang, Lin Zhu, Shu Xu, Xi Tan, Xinyuan Wang, Jianling Mai, Qinxiang Tan
    13-05-2024
    https://doi.org/10.4081/ejh.2024.3917
    2174
    PDF: 927
    HTML: 57
  • Receptor-mediated endocytosis of lysozyme in renal proximal tubules of the frog Rana temporaria

    E.V. Seliverstova, N.P. Prutskova
    13-04-2015
    https://doi.org/10.4081/ejh.2015.2482
    2616
    PDF: 873
    HTML: 1138
  • Endoplasmic reticulum stress contributed to inflammatory bowel disease by activating p38 MAPK pathway

    Yan Long, Yan Zhao, Xiaoqing Ma, Ya Zeng, Tian Hu, Weijie Wu, Chongtian Deng, Jinyue Hu, Yueming Shen
    23-05-2022
    https://doi.org/10.4081/ejh.2022.3415
    2569
    PDF: 1277
    HTML: 64
  • Localization of avβ6 integrin-TGF-β1/Smad3, mTOR and PPARγ in experimental colorectal fibrosis

    G. Latella, A. Vetuschi, R. Sferra, S. Speca, E. Gaudio
    e40
    04-12-2013
    https://doi.org/10.4081/ejh.2013.e40
    3848
    PDF: 1080
    HTML: 638
  • Senescence-associated ß-galactosidase staining over the lifespan differs in a short- and a long-lived fish species

    Simon Schöfer, Sylvia Laffer, Stefanie Kirchberger, Michael Kothmayer, Renate Löhnert, Elmar E. Ebner, Klara Weipoltshammer, Martin Distel, Oliver Pusch, Christian Schöfer
    29-02-2024
    https://doi.org/10.4081/ejh.2024.3977
    2362
    PDF: 1308
    Supplementary: 124
    HTML: 238
  • Expression of Ser729 phosphorylated PKCepsilon in experimental crescentic glomerulonephritis: an immunohistochemical study

    V.N. Karavana, H. Gakiopoulou, E.A. Lianos
    15-04-2014
    https://doi.org/10.4081/ejh.2014.2308
    2279
    PDF: 991
    HTML: 650
  • Interaction between sphingosine kinase/sphingosine 1 phosphate and transforming growth factor-β/Smads pathways in experimental intestinal fibrosis. An in vivo immunohistochemical study

    Roberta Sferra, Simona Pompili, Luca Ventura, Caroline Dubuquoy, Silvia Speca, Eugenio Gaudio, Giovanni Latella, Antonella Vetuschi
    31-07-2018
    https://doi.org/10.4081/ejh.2018.2956
    2070
    PDF: 1040
    Supplementary: 233
    HTML: 49
  • Aortic dissection is associated with reduced polycystin-1 expression, an abnormality that leads to increased ERK phosphorylation in vascular smooth muscle cells

    J. Feng, S. Ge, L. Zhang, H. Che, C. Liang
    16-12-2016
    https://doi.org/10.4081/ejh.2016.2711
    2722
    PDF: 1194
    HTML: 316
  • Subcellular localization and distribution of the reduced folate carrier in normal rat tissues

    M. Hinken, S. Halwachs, C. Kneuer, W. Honscha
    e3
    27-01-2011
    https://doi.org/10.4081/ejh.2011.e3
    1990
    PDF: 763
    HTML: 5832
  • Immunocytochemical staining for lymphatic and blood vessels with frozen sections: using LYVE-1 for lymphatic vessel and von Willebrand factor for blood vessel marker

    Tatsuo Tomita, Kunie Mah
    31-07-2026
    https://doi.org/10.4081/ejh.2026.4564
    182
    PDF: 21
    HTML: 0
  • Optimization of the tartrate-resistant acid phosphatase detection by histochemical method

    M. J. Galvão, A. Santos, M. D. Ribeiro, A. Ferreira, F. Nolasco
    e1
    18-02-2011
    https://doi.org/10.4081/ejh.2011.e1
    1636
    PDF: 759
    HTML: 899
  • Energy Dispersive X-ray (EDX) microanalysis: A powerful tool in biomedical research and diagnosis

    Manuel Scimeca, Simone Bischetti, Harpreet Kaur Lamsira, Rita Bonfiglio, Elena Bonanno
    15-03-2018
    https://doi.org/10.4081/ejh.2018.2841
    15825
    PDF: 7433
    HTML: 545
  • Effect of Danggui Buxue decoction on hypoxia-induced injury of retinal Müller cells in vitro

    Xilin Ge, Caoxin Huang, Wenting Chen, Chen Yang, Wenfang Huang, Jia Li, Shuyu Yang
    25-11-2024
    https://doi.org/10.4081/ejh.2024.4140
    2208
    PDF: 747
    HTML: 34
  • Nuclear factor-kB and nitric oxide synthases in red blood cells: good or bad in obesity? A preliminary study

    Monika Široká, Caterina Franco, Zuzana Guľašová, Zdenka Hertelyová, Vladimíra Tomečková, Luigi F. Rodella, Rita Rezzani
    21-01-2020
    https://doi.org/10.4081/ejh.2020.3081
    1868
    PDF: 900
    HTML: 24
  • Dipeptidylpeptidase-­IV, a key enzyme for the degradation of incretins and neuropeptides: activity and expression in the liver of lean and obese rats

    E. Tarantola, V. Bertone, G. Milanesi, E. Capelli, A. Ferrigno, D. Neri, M. Vairetti, S. Barni, I. Freitas
    e41
    08-10-2012
    https://doi.org/10.4081/ejh.2012.e41
    1838
    PDF: 930
    HTML: 1093
  • Colchicine alleviates severe acute pancreatitis in rats by inhibiting acinar cell ferroptosis via LCN2/MAPK/ERK signaling axis

    Liu Yang, Xiaoyi Zheng, Yang Zhang, Yue Li, Lei Li, Feng Liu
    11-05-2026
    https://doi.org/10.4081/ejh.2026.4557
    496
    PDF: 830
    Supplementary: 51
    HTML: 18
  • Histochemical characterization of TDAG51 in endothelial remodeling and angiogenesis following myocardial infarction via PI3K-AKT signaling

    Kaizheng Liu, Jinyu Pan, Quan Liu, Yang Huang, Liqun Shang, Yi Zhang, Jinming Wen, Huayang Li, Zhongkai Wu
    15-06-2026
    https://doi.org/10.4081/ejh.2026.4569
    248
    PDF: 196
    HTML: 8
  • Angiotensin II: immunohistochemical study in Sardinian pterygium

    P. Demurtas, M. Corrias, I. Zucca, C. Maxia, F. Piras, P. Sirigu, M.T. Perra
    28-07-2014
    https://doi.org/10.4081/ejh.2014.2426
    2247
    PDF: 830
    HTML: 367
  • The expression of Sirtuins 1 and 4 in peripheral blood leukocytes from patients with type 2 diabetes

    R. Song, W. Xu, Y. Chen, Z. Li, Y. Zeng, Y. Fu
    e10
    21-03-2011
    https://doi.org/10.4081/ejh.2011.e10
    2206
    PDF: 707
    HTML: 982
  • Altered alkaline phosphatase activity in obese Zucker rats liver respect to lean Zucker and Wistar rats discussed in terms of all putative roles ascribed to the enzyme

    V. Bertone, E. Tarantola, A. Ferrigno, E. Gringeri, S. Barni, M. Vairetti, I. Freitas
    e5
    08-02-2011
    https://doi.org/10.4081/ejh.2011.e5
    1540
    PDF: 840
    HTML: 3579
  • Forever particles: histochemistry in the plasticene age

    Beatrice Camia, Andrea Casasco, Manuela Monti
    01-08-2025
    https://doi.org/10.4081/ejh.2025.4226
    1559
    PDF: 685
    HTML: 64
  • Immunolocalization of endocan during the endothelial-mesenchymal transition process

    L. M. Carrillo, E. Arciniegas, H. R. Rojas, R. E. Ramirez
    e13
    01-06-2011
    https://doi.org/10.4081/ejh.2011.e13
    1507
    PDF: 609
    HTML: 1395
  • Dipeptidylpeptidase-IV activity and expression reveal decreased damage to the intrahepatic biliary tree in fatty livers submitted to subnormothermic machine-perfusion respect to conventional cold storage

    E. Tarantola, V. Bertone, G. Milanesi, C. Gruppi, A. Ferrigno, M. Vairetti, S. Barni, I. Freitas
    17-07-2014
    https://doi.org/10.4081/ejh.2014.2414
    1967
    PDF: 860
    HTML: 576
  • Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells

    Huina Su, Ruiqiong Ma, Dehui Su, Cheng Tan, Ye Zhu, Xin Yang
    21-04-2026
    https://doi.org/10.4081/ejh.2026.4537
    1071
    PDF: 645
    HTML: 23
  • Immunohistochemical detection of putative pathogenetic factors in adhesions of infants: a pilot study

    Arvis Pauliņš, Anna Junga, Māra Pilmane
    10-02-2026
    https://doi.org/10.4081/ejh.2026.4438
    354
    PDF: 484
    HTML: 13
  • Histochemistry as a versatile research toolkit in biological research, not only an applied discipline in pathology

    Carlo Pellicciari
    21-12-2018
    https://doi.org/10.4081/ejh.2018.3006
    2246
    PDF: 846
    HTML: 33
  • HLA-G expression and role in advanced-stage classical Hodgkin lymphoma

    G. Caocci, M. Greco, D. Fanni, G. Senes, R. Littera, S. Lai, P. Risso, C. Carcassi, G. Faa, G. La Nasa
    11-04-2016
    https://doi.org/10.4081/ejh.2016.2606
    2766
    PDF: 896
    HTML: 239
  • Swertianolin ameliorates immune dysfunction in sepsis via blocking the immunosuppressive function of myeloid-derived suppressor cells

    Zongfang Ren, Haoren Tang, Linjun Wan, Xing Liu, Ning Tang, Lingling Wang, Zhenhui Guo
    01-09-2021
    https://doi.org/10.4081/ejh.2021.3292
    1614
    PDF: 1077
    HTML: 41
  • Adipose-derived stem cells promote the recovery of intestinal barrier function by inhibiting the p38 MAPK signaling pathway

    Mei Yang, Wangbin Xu, Chaofu Yue, Rong Li, Xian Huang, Yongjun Yan, Qinyong Yan, Shisheng Liu, Yuan Liu, Qiaolin Li
    21-01-2025
    https://doi.org/10.4081/ejh.2025.4158
    1970
    PDF: 668
    Supplementary Figure: 117
    HTML: 63
  • Inhibition of fibrous adhesion formation in the temporomandibular joint of tenascin-C knockout mice

    Y. Shinohara, K. Okamoto, Y. Goh, N. Kiga, I. Tojyo, S. Fujita
    22-10-2014
    https://doi.org/10.4081/ejh.2014.2337
    3036
    PDF: 1003
    HTML: 505
  • VEGF promotes diabetic retinopathy by upregulating the PKC/ET/NF-κB/ICAM-1 signaling pathway

    Meiying Zhang, Min Zhou, Xia Cai, Yan Zhou, Xueling Jiang, Yan Luo, Yue Hu, Rong Qiu, Yanrong Wu, Yuejin Zhang, Yan Xiong
    27-10-2022
    https://doi.org/10.4081/ejh.2022.3522
    2742
    PDF: 1110
    HTML: 50
  • miR-129-5p regulates HMGB1/RAGE axis to inhibit pyroptosis and ameliorate cervical epithelial cell deterioration

    Huafang Wang, Dilidaer Sidike, Pan Liu, Longge Suo, Huerxidan Niyazi
    23-09-2025
    https://doi.org/10.4081/ejh.2025.4238
    539
    PDF: 484
    HTML: 16
  • Neurodegeneration in zebrafish embryos and adults after cadmium exposure

    Antonio Monaco, Teresa Capriello, Maria C. Grimaldi, Valentina Schiano, Ida Ferrandino
    19-10-2017
    https://doi.org/10.4081/ejh.2017.2833
    3419
    PDF: 1370
    HTML: 159
  • Activation of the renin-angiotensin system in mice aggravates mechanical loading-induced knee osteoarthritis

    Kotaro Yamagishi, Ichiro Tsukamoto, Fumihisa Nakamura, Kazuhiko Hashimoto, Kazuhiro Ohtani, Masao Akagi
    24-07-2018
    https://doi.org/10.4081/ejh.2018.2930
    2092
    PDF: 1155
    HTML: 166
  • Histochemistry as an irreplaceable approach for investigating functional cytology and histology

    C. Pellicciari
    e41
    19-12-2013
    https://doi.org/10.4081/ejh.2013.e41
    3458
    PDF: 966
    HTML: 413
  • Human equilibrative nucleoside transporter 1 and carcinoma of the ampulla of Vater: expression differences in tumour histotypes

    G. Perrone, S. Morini, D. Santini, C. Rabitti, B. Vincenzi, R. Alloni, A. Antinori, P. Magistrelli, R. Lai, C. Cass, J. R. Mackey, R. Coppola, G. Tonini, A. Onetti Muda
    e38
    13-09-2010
    https://doi.org/10.4081/ejh.2010.e38
    1554
    PDF: 758
    HTML: 1775
  • Expression and role of cocaine-amphetamine regulated transcript (CART) in the proliferation of biliary epithelium

    Arianna Casini, Giorgio Vivacqua, Rosa Vaccaro, Anastasia Renzi, Stefano Leone, Luigi Pannarale, Antonio Franchitto, Paolo Onori, Romina Mancinelli, Eugenio Gaudio
    19-10-2023
    https://doi.org/10.4081/ejh.2023.3846
    1887
    PDF: 710
    HTML: 35
  • Leptin affects filopodia and cofilin in NK-92 cells in a dose- and time-dependent manner

    Jana Oswald, Maximilian Büttner, Simon Jasinski-Bergner, Roland Jacobs, Philip Rosenstock, Heike Kielstein
    26-01-2018
    https://doi.org/10.4081/ejh.2018.2848
    3436
    PDF: 1266
    HTML: 125
  • Maresin 1 alleviates myocardial ischemia-reperfusion injury in rats by suppressing inflammation

    Hongkai Xiao, Jinghu Liu, Qinhong Cai, Siyu Liang, Zhitao Hu, Xiaochao Chen
    13-10-2025
    https://doi.org/10.4081/ejh.2025.4254
    953
    PDF: 476
    HTML: 44
  • Histochemistry in biology and medicine: a message from the citing journals

    Carlo Pellicciari
    23-12-2015
    https://doi.org/10.4081/ejh.2015.2610
    3296
    PDF: 928
    HTML: 901
  • Twenty years of histochemistry in the third millennium, browsing the scientific literature

    Carlo Pellicciari
    29-12-2020
    https://doi.org/10.4081/ejh.2020.3213
    1476
    PDF: 572
    HTML: 17
  • Epidermal growth factor-like domain multiple 7 (EGFL7): Expression and possible effect on biliary epithelium growth in cholangiocarcinoma

    Caterina L. Mammola, Antonella Vetuschi, Luigi Pannarale, Roberta Sferra, Romina Mancinelli
    30-11-2018
    https://doi.org/10.4081/ejh.2018.2971
    1511
    PDF: 840
    Supplementary: 200
    HTML: 32
  • Aberrant DKK3 expression in the oral leukoplakia and oral submucous fibrosis: a comparative immunohistochemical study

    T. Al-dhohorah, M. Mashrah, Z. Yao, J. Huang
    16-06-2016
    https://doi.org/10.4081/ejh.2016.2629
    2848
    PDF: 899
    HTML: 351
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
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20 April 2026
Vol. 70 No. 2 (2026)
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells
Huina Su et al.
21 April 2026
Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

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pISSN: 1121-760X
eISSN: 2038-8306

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