Ultrastructure of telocytes, a new type of interstitial cells in the myocardium of the Chinese giant salamander (Andrias davidianus)

  • Tingting Ge College of Life Science and Engineering, Foshan University; College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, China.
  • Yaqiong Ye College of Life Science and Engineering, Foshan University, China.
  • Hui Zhang | zhanghui429@hotmail.com College of Life Science and Engineering, Foshan University; College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, China.

Abstract

Telocytes (TCs) are new interstitial cells, and they are involved in tissue regeneration, particularly in heart. Therefore, TCs are suggested to be a promising cell in regenerative medicine. However, the information of location structural characteristics and functions of TCs is still limited. In this study, cardiac TCs of the Chinese giant salamanders (Andrias davidianus) were identified by transmission electron microscopy. TCs were located in the interstitium between cardiomyocytes (CM). TCs possessed distinctive ultrastructural characteristics, including one to two very long and thin moniliform telopodes (Tps), emerging points from the cell body, caveolae, dichotomous branchings, labyrinthic systems, neighbouring exosomes and homo-cellular contacts between Tps. TCs/Tps were frequently observed in close proximity to cardiomyocytes. Moreover, Tps established hetero-cellular contacts with cardiomyocytes. Our results confirm the presence of TCs in the myocardium of the A. davidianus. This will help us to better understand roles of TCs in amphibian hearts.

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Published
2019-05-23
Section
Original Papers
Supporting Agencies
National Natural Science Foundation of China (No. 31560681 and 31760716), Project of Jiangxi Province (No. 20151BBF60007 and 20171ACB21028), Project of Education Department of Jiangxi Province (No. GJJ160418)
Keywords:
Amphibian, cardiomyocytes, telocytes, telopodes, ultrastructure
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How to Cite
Ge, T., Ye, Y., & Zhang, H. (2019). Ultrastructure of telocytes, a new type of interstitial cells in the myocardium of the Chinese giant salamander (Andrias davidianus). European Journal of Histochemistry, 63(2). https://doi.org/10.4081/ejh.2019.3021