Niemann-Pick disease, type B with TRAP-positive storage cells and secondary sea blue histiocytosis

Abstract

We present 2 cases of Niemann Pick disease, type B with secondary sea-blue histiocytosis. Strikingly, in both cases the Pick cells were positive for tartrate resistant acid phosphatase, a finding hitherto described only in Gaucher cells. This report highlights the importance of this finding as a potential cytochemical diagnostic pitfall in the diagnosis of Niemann Pick disease.

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Published
2009-09-23
Section
Letters to the Editor
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How to Cite
Sharma, P., Kar, R., Dutta, S., Pati, H., & Saxena, R. (2009). Niemann-Pick disease, type B with TRAP-positive storage cells and secondary sea blue histiocytosis. European Journal of Histochemistry, 53(3), e22. https://doi.org/10.4081/ejh.2009.e22