Niemann-Pick disease, type B with TRAP-positive storage cells and secondary sea blue histiocytosis
AbstractWe present 2 cases of Niemann Pick disease, type B with secondary sea-blue histiocytosis. Strikingly, in both cases the Pick cells were positive for tartrate resistant acid phosphatase, a finding hitherto described only in Gaucher cells. This report highlights the importance of this finding as a potential cytochemical diagnostic pitfall in the diagnosis of Niemann Pick disease.
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Copyright (c) 2009 P. Sharma, R. Kar, S. Dutta, H.P. Pati, R. Saxena
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