Expression of progesterone receptor membrane component-1 in bovine reproductive system during estrous cycle

  • A.M. Luciano | alberto.luciano@unimi.it University of Milan, Department of Animal Sciences, Italy.
  • D. Corbani University of Milan, Italy.
  • V. Lodde University of Milan, Italy.
  • I. Tessaro University of Milan, Italy.
  • F. Franciosi University of Milan, Italy.
  • J.J. Peluso University of Connecticuy, United States.
  • S. Modina University of Milan, Italy.

Abstract

Several reports suggest the participation of progesterone receptor membrane component 1 (PGRMC1) in progesterone signaling in the reproductive system. This study aimed at investigating the presence and localization of PGRMC1 in bovine ovary, oviduct and uterus, during the follicular and luteal phases of the estrous cycle. In the ovary, PGRMC1 has been detected in surface germinal epithelium, granulosa cells, theca cells and in the germinal vesicle of the oocytesat all stages of folliculogenesis. In the corpus luteum the expression of PGRMC1 was influenced by the stage of the estrous cycle. In the oviducts and in the uterus horns, PGRMC1 was immunolocalized in the luminal epithelium, in the muscle layer cells and in the endothelial cells. In the uterus, PGRMC1 was intensely localized also in the glandular endometrium. However, in the oviducts and in the uterus horns, the localization of PGRMC1 was independent on the stage of the estrous cycle and on whether evaluating the ipsilateral or the contralateral organ. In conclusion, the present immunohistochemical study showed that PGRMC1 is located in various compartments of the bovine female reproductive organs. With the exception of the corpora lutea, PGRMC1 localization showed similar pattern during different stage of the estrous cycle.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Author Biographies

A.M. Luciano, University of Milan, Department of Animal Sciences

Department of Animal Sciences, Division of Veterinary Anatomy and Histology, Faculty of Veterinary Medicine, University of Milan

PhD, Associate Professor

D. Corbani, University of Milan

Department of Animal Sciences, Division of Veterinary Anatomy and Histology, Faculty of Veterinary Medicine, University of Milan

DMV, PhD student

V. Lodde, University of Milan

Department of Animal Sciences, Division of Veterinary Anatomy and Histology, Faculty of Veterinary Medicine, University of Milan

PhD, Researcher

I. Tessaro, University of Milan

Department of Animal Sciences, Division of Veterinary Anatomy and Histology, Faculty of Veterinary Medicine, University of Milan

PhD, Post Doctoral fellow

F. Franciosi, University of Milan

Department of Animal Sciences, Division of Veterinary Anatomy and Histology, Faculty of Veterinary Medicine, University of Milan

DVM, PhD, Post Doctoral fellow

J.J. Peluso, University of Connecticuy

Departments of Cell Biology, University of CT Health Center, Farmington, CT USA

PhD, Full Professor
S. Modina, University of Milan

Department of Animal Sciences, Division of Veterinary Anatomy and Histology, Faculty of Veterinary Medicine, University of Milan

DVM, PhD, Associate Professor

Published
2011-09-21
Info
Issue
Section
Original Papers
Keywords:
Uterus, oviduct, ovary, corpus luteum, follicle, oocyte, progesterone receptor
Statistics
  • Abstract views: 643

  • PDF: 302
  • Figures 1 and 2: 0
  • Figures 3 and 4: 0
  • Figure 5: 0
How to Cite
Luciano, A., Corbani, D., Lodde, V., Tessaro, I., Franciosi, F., Peluso, J., & Modina, S. (2011). Expression of progesterone receptor membrane component-1 in bovine reproductive system during estrous cycle. European Journal of Histochemistry, 55(3), e27. https://doi.org/10.4081/ejh.2011.e27