@article{Nicolin_Narducci_Celeghini_2009, title={Effect of recombinant TRAIL in a murine co-culture system of osteoclastogenesis}, volume={52}, url={https://www.ejh.it/ejh/article/view/1189}, DOI={10.4081/1189}, abstractNote={Although some experimental evidence has implicated the TRAIL/TRAIL-receptor system in the regulation of osteoclastogenesis, the only available studies performed so far have been performed on isolated pre-osteoclasts, induced to differentiate by the addition of recombinant RANKL and M-CSF. Using a more physiological co-culture system in the absence of exogenous cytokines, we have here demonstrated that recombinant TRAIL inhibits osteoclast formation, but only at relatively high concentrations (500 ng/mL).}, number={1}, journal={European Journal of Histochemistry}, author={Nicolin, V and Narducci, P and Celeghini, C}, year={2009}, month={Aug.}, pages={75–78} }