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Species diversity regarding the presence of proximal tubular progenitor cells of the kidney
1815PDF: 683Supplementary: 269HTML: 363 -
2D vs 3D morphological analysis of dorsal root ganglia in health and painful neuropathy
2541PDF: 1452Video 1: 194Video 2: 208HTML: 16 -
5XFAD MOUSE MODEL: INVESTIGATING BRAIN IRON IMBALANCE AND MITOCHONDRIAL FEATURES’ ALTERATION Mezzanotte M1, Chicote J1, Scimia N1, Riganti C2, Porporato PE3 and Stanga S1 | 1Neuroscience Institute Cavalieri Ottolenghi, Department of Neuroscience Rita Levi Montalcini, University of Turin, Italy; 2Department of Oncology, Oncological Pharmacology Lab, University of Turin, Italy; 3Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Turin, Italy
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MITOCHONDRIAL DYSFUNCTION AS A KEY FACTOR OF MOTOR NEURON DEGENERATION: INSIGHTS FROM AMYOTROPHIC LATERAL SCLEROSIS CELLULAR MODELS Scimia N¹, Carletti RM², Rasà MD¹, Ferrari D3, Boido M¹ and Stanga S¹ | ¹Neuroscience Institute Cavalieri Ottolenghi, Orbassano (TO), Department of Neuroscience Rita Levi Montalcini, University of Turin, Italy; ²Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy; 3Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
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Functional topography of the fully grown human oocyte
1842PDF: 757HTML: 244 -
P28 | EXPLORING THE POTENTIAL LINK BETWEEN MITOCHONDRIAL DYSFUNCTION AND MITO-EVS IN PANCREATIC DUCTAL ADENOCARCINOMA (PDAC) V. Giansante1, L. Leanza2, E. Guerra3, F. Vianello4, C. Iacovino1, S. Lattanzio1, L. Morello1, G. Stati1, P. Simeone3, P. Lanuti3, S. Alberti5, M. Reichert6, R. Di Pietro1 | 1Department of Medicine and Ageing Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy; 2Department of Biology, University of Padua, Padua, Italy; 3Department of Medicine and Ageing Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST)G. d’Annunzio” University of Chieti-Pescara, Italy; 4Department of Biology, University of Padua, Padua, Italy; 5Unit of Medical Genetics, Department of Biomedical Sciences, University of Messina, Messina, Italy; 6Translational Pancreatic Cancer Research Center, Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany; Center for Organoid Systems (COS), Technical University of Munich, Garching, Germany
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Genome size evaluations in cockroaches: new entries
1266PDF: 709HTML: 24 -
P80 | MITOCHONDRIA-LYSOSOME INTERACTIONS: EMERGING PLAYERS IN GLIOMA L. Zeppa1, M.B. Morelli2, C. Aguzzi2, M. Giangrossi2, M. Nabissi2, G. Cameli2, G. Santoni2, S.K. Tayebati2, V. Bellitto1, D. Tomassoni1, C. Amantini1 | 1School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy; 2School of Pharmacy, University of Camerino, Camerino, Italy
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Reliable hexokinase 3 protein detection in human cell lines and primary tissue
1306PDF: 293Supplementary: 32Uncropped Western blots: 23HTML: 3 -
AN INDUCED PLURIPOTENT STEM CELL MODEL OF FLVCR1-RELATED NEUROPATHY UNCOVERS MITOCHONDRIAL AND MEMBRANE DISORGANIZATION IN SENSORY NEURONS Zanin Venturini DI1, Kopecka J2, Zhao B3, Yu TW3, Abalai RE1, Metani L1, Salio C4, Riganti C2, Tolosano E1 and Chiabrando D1 | 1Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center (MBC) “Guido Tarone”, University of Torino, Turin, Italy; 2Department of Oncology, Molecular Biotechnology Center, University of Turin, Italy; 3Division of Genetics and Genomics, Boston Children’s Hospital, Boston, MA, Harvard Medical School, USA; 4Department of Veterinary Sciences, University of Torino, Turin, Italy
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Management of autofluorescence in formaldehyde-fixed myocardium: choosing the right treatment
1414PDF: 763Supplementary: 89HTML: 19 -
ON THE WAY TO A NEW MODEL OF NEURODEGENERATION? FIRST EVIDENCE OF THE EXPRESSION OF GATA1 IN THE BRAIN: CORRELATIONS WITH AGING, MITOCHONDRIAL DAMAGE AND SYNUCLEINOPATHY C. Caturano1, F. E. Bellomi1, F. Arciprete1, V. Velardi1, L. La Barbera2, M. Falchi3, M. Bacioglu4, R. Mancinelli5, M. D’Amelio2, M. Spillantini4, M. Zingariello1, G. Vivacqua1,6 | 1Laboratory of Microscopic and Ultrastructural Anatomy, Campus Biomedico University of Rome, Italy; 2Laboratory of Molecular Neuroscience - Campus Biomedico University of Rome, Italy; 3National Centre for HIV/AIDS Research, Istituto Superior di Sanità, Rome, Italy; 4Department of Clinical Neuroscience, The University of Cambridge, Cambridge, UK; 5Department of Anatomic, Histologic, Forensic Medicine and Locomotor Apparatus Science, Sapienza University of Rome, Italy; 6Department of Clinical Neuroscience, The University of Cambridge, Cambridge, UK
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ECRG4 expression in normal rat tissues: expression study and literature review
2566PDF: 1078Supplementary: 346HTML: 1008 -
Is there still room for novelty, in histochemical papers?
2472PDF: 661HTML: 276 -
P15 | PHB/JAK/H3Y41PH AXIS REGULATES MEIOTIC RECOMBINATION IN SPERMATOGENESIS H. Chen1, L. Zhang1, W. Tan-Tai1, M. Liu2, H. Shi3, W. O4, P.A. Martin-DeLeon5 | 1Department of Anatomy, Histology & Embryology, Shanghai Medical College, Fudan University, Shanghai, China; 2State Key Laboratory of Molecular Biology, Chinese Academy of Sciences-University of Chinese Academy of Sciences, Shanghai, China; 3NHC Key Lab of Reproduction Regulation, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai, China; 4School of Biomedical Sciences, The University of Hong Kong, Hong Kong SAR, China; 5Department of Biological Sciences, University of Delaware, Newark, USA
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THE ROLE OF RETINAL mTOR IN RETINAL DEGENERATION Lazzeri G1, Lenzi P1, Ferrucci M1, Biagioni F2, Busceti CL2, Giambelluca M1, Puglisi-Allegra S2 and Fornai F1,2 | 1Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa; 2IRCCS, Neuromed, Pozzilli, Italy
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P18 | NESTIN EXPRESSION IN THE MYOCARDIUM OF SPONTANEOUSLY HYPERTENSIVE RATS AND CONPLASTIC SHR-MTBN STRAIN, AND CO-EXPRESSION WITH CONNEXIN 43 D. Cizkova1, J. M. Zurmanova2, T. Artykov1, F. Galatik2, B. Elsnicova2, J. Silhavy3, M. Pravenec3, J. Mokry1 | 1Department of Histology and Embryology, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic; 2Department of Physiology, Faculty of Science, Charles University, Prague, Czech Republic; 3Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic
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EXPERIMENTAL PARKINSONISM RECRUITS CHOLINERGIC MEDIAL SEPTAL NEURONS Lenzi P1, Lazzeri G1, Ferrucci M1, Scotto M1, Giambelluca MA1, Binda P1 and Fornai F1,2 | 1Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Italy; 2IRCCS, Neuromed, Pozzili, Italy
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Fine structural detection of calcium ions by photoconversion
1547PDF: 678Supplementary: 264HTML: 134 -
P07 | DISRUPTED GUT-VASCULAR BARRIER AND INFLAMMATORY REMODELING IN MNGIE: A SPATIAL TRANSCRIPTOMIC AND HISTOLOGICAL STUDY S. Blando1, E. Boschetti1, I. Neri1, L. Caporali2, C. Fiorini2, D. Ormanbekova2, C. Malagelada3, I. Rusciano1, V. Carelli2, R. De Giorgio4, L. Manzoli1, S. Ratti1 | 1Center of Clinical Surgical Molecular and Experimental Anatomy Alma Mater Studiorum, University of Bologna, Italy; 2IRCCS Institute of Neurological Sciences of Bologna, Neurogenetics Program, Bologna, Italy; 3Departament de Medicina, Universitat Autonoma de Barcelona, Barcelona, Spain; 4Department of Translational Medicine, University of Ferrara, Ferrara, Italy
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P11 | DOMINO TRANSPLANTATION IN MNGIE: IS THE LIVER A SUITABLE GRAFT? E. Boschetti1, I. Neri1, S. Blando1, C. Malagelada2, L. Caporali3, R. D’Angelo4, R. Rinaldi4, S. Mongiorgi1, V. Carelli3, R. De Giorgio5, L. Manzoli1, S. Ratti1 | 1Center of Clinical Surgical Molecular and Experimental Anatomy Alma Mater Studiorum – University of Bologna, Italy; 2Digestive System Research Unit, University Hospital Vall d’Hebron; Barcelona, Spain; 3IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy; 4IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; 5Department of Translational Medicine, University of Ferrara, Ferrara, Italy
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miR-199a-5p inhibited HIF-1α to suppress the proliferation, migration, and differentiation of cardiac stem cells
185PDF: 143Supplementary: 11HTML: 3 -
How to stain nucleic acids and proteins in Miller spreads
1694PDF: 449HTML: 46 -
GENERATION AND CHARACTERIZATION OF A KNOCK-IN MOUSE MODEL FOR FLVCR1-RELATED SENSORY NEUROPATHY Abalai RE1, Marvaldi L2, Ferrini F3, Riganti C1, Zanin Venturini DI1, Metani L1, Tolosano E1 and Chiabrando D1 | 1Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center “Guido Tarone”, University of Torino, Turin, Italy; 2Neuroscience Institute Cavalieri Ottolenghi, Orbassano (TO), Italy; 3Dipartimento di Morfofisiologia Veterinaria and Rita Levi Montalcini Center for Brain Repair, Grugliasco (TO), Italy
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HACAT CELLS AS A 2D EXPERIMENTAL DIFFERENTIATING MODEL TO ANALYZE THE EARLY BIOLOGICAL EFFECTS INDUCED BY A PSORIATIC PROINFLAMMATORY MICROENVIRONMENT: CELL PROLIFERATION, DIFFERENTIATION AND FERROPTOSIS F. Riva1, S. Recalcati2, E. Gammella2, D. Daluiso1, F. Prignano3, E. Donetti2 | 1Dept. Public Health, Experimental and Forensic Medicine; Histology and Embryology Unit, University of Pavia, Pavia, Italy; 2Dept. Biomedical Sciences for Health, University of Milan, Milan, Italy; 3Dept. Health Sciences, Section of Dermatology, University of Florence, Florence, Italy
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NO-tryptophan: a new small molecule located in the rat brain
1792PDF: 518HTML: 241 -
TRACKING HER2 TRAFFICKING AND ORGANELLE CROSSTALK IN TRASTUZUMAB-DERUXTECAN–TREATED BREAST CANCER CELLS USING MULTIMODAL IMAGING E. Tagliatti1, M. C. Gagliani2, G. Bellese2, M. Crippa3, A. Abbona4, M. Paccagnella4, P. Arnaldi5, M. C. Merlano6, O. Garrone7, A.M. Porcelli8, M. Matteoli1, P. Falletta9, P. Castagnola10, K. Cortese2 | 1IRCCS Humanitas Research Hospital, Laboratory of Pharmacology and Brain Pathology, Rozzano, Milano, Italy; 2DIMES, Department of Experimental Medicine, Cellular Electron Microscopy Lab, University of Genoa, Genoa, Italy; 3Experimental Imaging Center, IRCCS Ospedale San Raffaele, Milan, Italy; 4Health Department S. Croce e Carle Teaching Hospital, Cuneo, Italy; 5IRCCS Ospedale Policlinico San Martino, Genova, Italy; 6Scientific Direction, Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy; 7Medical Oncology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy; 8FABIT, Department of Pharmacy and Biotechnology and CIRI, Interdepartmental Centre for Industrial Research ‘Scienze Della Vita e Tecnologie per La Salute’, University of Bologna, Bologna, Italy; 9Vita-Salute San Raffaele University, Milan, Italy; 10IRCCS Ospedale Policlinico San Martino, Genova, Italy
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PRMT1 arginine methyltransferase accumulates in cytoplasmic bodies that respond to selective inhibition and DNA damage
2779PDF: 662Supplementary: 298HTML: 795
