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• LOCUS COERULEUS STRUCTURAL INTEGRITY IS ASSOCIATED WITH CIRCULATING SOLUBLE AXL IN ALZHEIMER’S DISEASE Galgani A¹, Scotto M², Mary A³, Lombardo F⁴, Martini N⁴, Siciliano G⁵, Ceravolo R⁵, Heneka MT^3,6 and Giorgi FS^1,7 | ¹Department of Translational Research and of New Surgical and Medical Technologies, University of Pisa, Pisa, Italy; ²Laboratory of Medical Science, Institute of Life Sciences, Scuola Superiore Sant’Anna, Pisa, Italy; ³Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg; ⁴Department of Radiology, Fondazione Toscana “G. Monasterio”, Pisa, Italy; ⁵Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; ⁶Division of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, USA; ⁷I.R.C.C.S. Stella Maris, Calambrone, Pisa, Italy

  12-12-2025

  https://doi.org/10.4081/ejh.2025.4467

  172

• SODIUM-CALCIUM EXCHANGER PIVOTAL ROLE IN OXALIPLATIN-INDUCED ALTERATIONS LEADING TO PERIPHERAL NEUROTOXICITY, AXONAL DAMAGE AND NECROPTOSIS Di Girolamo S¹, Invernizzi C¹, Kraus MF³, Ballarini E¹ and Alberti P^1,2 | ¹Experimental Neurology Unit and Milan Center for Neuroscience, University of Milano-Bicocca, Monza, Italy; ²Department of Neurology, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy; ³S.C. Neuroscienze, Istituto Zooprofilattico Sperimentale del Piemonte Liguria e Valle D’Aosta, Torino, Italy

  12-12-2025

  https://doi.org/10.4081/ejh.2025.4468

  170

• CONTRIBUTION OF MAGNETIC RESONANCE IMAGING ASSOCIATED WITH MACHINE LEARNING TO AN EARLY ASSESSMENT OF THE CONVERSION OF MILD COGNITIVE IMPAIRMENT IN OVERT DEMENTIA Amenta F, Battineni G, Chintalapudi N and Traini E | Clinical Research Centre, School of Medicinal and Health Products Sciences, University of Camerino, Camerino, Italy

  12-12-2025

  https://doi.org/10.4081/ejh.2025.4469

  175