Insulin-induced iron loading in the rat brown adipose tissue: histochemical and electron-microscopic study

Abstract

In the present study we have reported an iron-loading in the rat brown adipose tissue (BAT) after 3-day treatment with insulin (4 IU/kg). Light microscopy showed numerous ironpositive cells (Perls’ stain) mainly macrophages and brown adipocytes, while electron-microscopic examination revealed lipofuscin granules and phagosomes as iron-containing components. These results clearly indicate that iron participates in damaging of brown adipocytes.

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Published
2009-06-26
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How to Cite
Kora, A., Vere, M., & Davidovi, V. (2009). Insulin-induced iron loading in the rat brown adipose tissue: histochemical and electron-microscopic study. European Journal of Histochemistry, 47(3), 241-244. https://doi.org/10.4081/833