What’s new in an old-fashioned journal of histochemistry?

Scientific journals experience, in these last years, a series of changes which will probably radically modify the aspect of the scientific literature as we have known it till now. From printed pages, the Journals are shifting toward online printing, new journals are appearing only in this form and have high impact factors; traditional, established journals have difficulties in making a living. Moreover, there is a constant drift toward new scientific trends which progressively modifies the journals themselves. In this view, the publications devoted to histochemistry and cytochemistry are representative. Almost all the journals in this field have slowly but steadily shifted from the description of methods and techniques to their application for solving problems in cell biology.This trend has been general, and has involved the journals of histochemistry in the United States and Europe as well.