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• STANDARDIZING LIGHT SHEET IMAGING AND 3D IMAGE ANALYSIS FOR WHOLE BRAIN VASCULAR NET QUANTIFICATION Zanella L¹, Moretti M¹, Quadalti C², Giardino L^1,3,4, Calzà L^2,3,4, Baldassarro VA^1,4 and Lorenzini L^1,4 | ¹Department of Veterinary Medical Science, University of Bologna, Ozzano dell’Emilia, Bologna, Italy; ²Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy; ³IRET Foundation, Ozzano dell’Emilia, Bologna, Italy; ⁴Interdepartmental Centre for Industrial Research in Health Sciences and Technology ICIR-HST, University of Bologna, Ozzano dell’Emilia, Bologna, Italy

  12-12-2025

  https://doi.org/10.4081/ejh.2025.4461

  357

• GLIAL INFLAMMASOME ACTIVATION AND BLOOD-BRAIN BARRIER BREAKDOWN IN AGE-RELATED NEURODEGENERATION Errede M¹, Girolamo F¹, d’Amati A^1,2, de Giorgis M¹, Lorusso L¹, Pierucci C³, Bernardini N³, Pellegrini C³, Virgintino D¹ and Annese T² | ¹University of Bari, Department of Translational Biomedicine and Neuroscience – Human Anatomy and Histology Unit, Bari, Italy; ²Libera Università del Mediterraneo (LUM) Giuseppe Degennaro University, Department of Medicine and Surgery, Bari, Italy; ³University of Pisa, Department of Clinical and Experimental Medicine - Unit of Histology and Medical Embryology, Pisa, Italy

  12-12-2025

  https://doi.org/10.4081/ejh.2025.4460

  536

• NEUROBIOLOGY OF SUICIDE: MORPHOLOGICAL ASSESSMENT OF MICROGLIAL NETWORK IN HUMAN POST-MORTEM PREFRONTAL CORTEX Tambuzzi S¹, Bertolotto N², Massari S², Madaschi L³, Alini M², Brandolese D², Ubezio MC¹, Cattaneo C¹ and Amadeo A² | ¹Institute of Forensic Medicine, Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy; ²Department of Biosciences, Università degli Studi di Milano, Milan, Italy; ³UNITECH NOLIMITS, Università degli Studi di Milano, Milan, Italy

  12-12-2025

  https://doi.org/10.4081/ejh.2025.4459

  336