Effects of monensin on Na+/K+-ATPase and Ca++-ATPase activities in chick skeletal muscle and myocardium after subacute treatment

  • M. Calò | mcalo@unime.it
  • P. Lo Cascio
  • P. Licata
  • A. Richetti
  • G. Zaccone
  • F. Naccari

Abstract

Chicks were treated at 2 weeks of age with 4, l5, 40, 100 and 150 mg/kg of monensin, an ionophore used for its anticoccidial and growth-promoting properties. In the present immunohistochemical study, the expressions and distribution of Na+/K+- ATPase and Ca++-ATPase were studied in myocardium and skeletal muscles (pectoral and quadriceps femoris). We detected an increase of Na+/K+-ATPase immunostaining with prominent staining of the sarcolemma and a slight increase of Ca++-ATPase with prominent staining of the sarcoplasma.

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Published
2010-05-14
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How to Cite
CalòM., Lo Cascio, P., Licata, P., Richetti, A., Zaccone, G., & Naccari, F. (2010). Effects of monensin on Na+/K+-ATPase and Ca++-ATPase activities in chick skeletal muscle and myocardium after subacute treatment. European Journal of Histochemistry, 46(4), 309-16. https://doi.org/10.4081/1742