Impact Factor 2025

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Downregulation of GMPS inhibited the proliferation of hepatocellular cancer cells via the regulation of STAT3/c-Myc pathway

Zhibin Guo, Juan Yu, Jing Sun, Sheng Yang, Jiang Pu

https://doi.org/10.4081/ejh.2026.4541

9

PDF: 3

Supplementary: 0

Histochemical characterization of TDAG51 in endothelial remodeling and angiogenesis following myocardial infarction via PI3K-AKT signaling

Kaizheng Liu, Jinyu Pan, Quan Liu, Yang Huang, Liqun Shang, Yi Zhang, Jinming Wen, Huayang Li, Zhongkai Wu

https://doi.org/10.4081/ejh.2026.4569

6

PDF: 2

Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells

Huina Su, Ruiqiong Ma, Dehui Su, Cheng Tan, Ye Zhu, Xin Yang

https://doi.org/10.4081/ejh.2026.4537

562

PDF: 390

HTML: 6

Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice

Nana Bao, Min Zhang, Ming Tang, Ziyi Shen, Shenglin Wang, Guohui Jiang

https://doi.org/10.4081/ejh.2026.4548

364

PDF: 255

Raw data: 39

HTML: 15

Histopathological and immunofluorescent characterization of post-sepsis immune dysregulation in a clinically relevant mouse model

Haoran Tang, Chen Liao, Ning Tang, Hui Li, Yi Liu, Lingling Wang, Zongfang Ren

https://doi.org/10.4081/ejh.2026.4435

477

PDF: 335

HTML: 12

Immunohistochemical detection of putative pathogenetic factors in adhesions of infants: a pilot study

Arvis Pauliņš, Anna Junga, Māra Pilmane

https://doi.org/10.4081/ejh.2026.4438

269

PDF: 215

HTML: 3

Overexpression of GPER1 suppressed esophageal carcinoma growth via activating cAMP pathway

Hongmei Yin, Xiumei Han, Qun Zhang, Duojie Li, Fan Wang

https://doi.org/10.4081/ejh.2026.4422

644

PDF: 368

Supplementary: 44

Original gels: 44

HTML: 12

Genetic deletion of P-selectin prevents fibrosis development by inhibiting the neutrophil megakaryocyte emperipolesis in the Gata1^low mouse model for myelofibrosis

Francesca Arciprete, Viola Velardi, Antonio Di Virgilio, Paola Verachi, Claudio Carta, Giulia Pozzi, Vincenzo Roberti, Giorgio Vivacqua, Rosalba Rana, Maria Zingariello

https://doi.org/10.4081/ejh.2025.4427

671

PDF: 339

HTML: 5

The hematopoietic stem cells supportive megakaryocytes as shapers of the bone marrow niche

Francesca Arciprete, Viola Velardi, Paola Verachi, Claudio Carta, Antonio Di Virgilio, Vincenzo Roberti, Giorgio Vivacqua, Rosalba Rana, Maria Zingariello

https://doi.org/10.4081/ejh.2025.4424

708

PDF: 291

HTML: 14

Transient receptor potential canonical 3/5 attenuate endothelial damage-induced neointima formation without affecting endothelial cell proliferation

Wenjun Zeng, Bei Liu, Lixia Yang, Ruiwei Guo

https://doi.org/10.4081/ejh.2025.4311

393

PDF: 194

HTML: 17

Placental mesenchymal stem cell exosomes drive macrophage M2 polarization via the miR-146a-5p/TRAF6 axis to ameliorate preeclampsia

Xiaoli Liu, Ruiyue Li, Junjie Sun, Yuanpei Yang, Lina Hu

https://doi.org/10.4081/ejh.2025.4426

897

PDF: 489

HTML: 16

Folic acid promotes autophagy to relieve metabolism-associated fatty liver disease by regulating NRF2

Yu Wen, Juan Luo, Chunjing Shi, Jie Wu

https://doi.org/10.4081/ejh.2025.4309

825

PDF: 538

HTML: 33

Maresin 1 alleviates myocardial ischemia-reperfusion injury in rats by suppressing inflammation

Hongkai Xiao, Jinghu Liu, Qinhong Cai, Siyu Liang, Zhitao Hu, Xiaochao Chen

https://doi.org/10.4081/ejh.2025.4254

638

PDF: 381

HTML: 39

Guilu Erxian oral liquid mitigates oxidative damage in spermatogonial cells via miR-6739-5p modulation and PI3K/AKT pathway activation: a functional histocytochemical study

Zefeng Sun, Xinrong Fan, Zhenquan Liu

https://doi.org/10.4081/ejh.2025.4253

385

PDF: 340

HTML: 37

miR-129-5p regulates HMGB1/RAGE axis to inhibit pyroptosis and ameliorate cervical epithelial cell deterioration

Huafang Wang, Dilidaer Sidike, Pan Liu, Longge Suo, Huerxidan Niyazi

https://doi.org/10.4081/ejh.2025.4238

428

PDF: 328

HTML: 11

miR-199a-5p inhibited HIF-1α to suppress the proliferation, migration, and differentiation of cardiac stem cells

Sha Li, Cuigai Zhang, Yanping Liu, Cuiqiao Meng, Yang Xie, Shuren Li

https://doi.org/10.4081/ejh.2025.4239

479

PDF: 329

Supplementary: 53

HTML: 18

Solamargine inhibited the progression of non-small cell lung cancer in vitro by activating T cells

Changchun Zhang, Yichen Sun, Wei Jiang, Lin Wu, Qi Fang, Qikun Wang

https://doi.org/10.4081/ejh.2025.4217

524

PDF: 206

HTML: 9

Effects of Notch signaling on proliferation, angiogenesis, and adipogenesis of hemangioma-derived stem cells

Weidong Wang, Sheng Chen, Yuan Wang, Cui Jie, Weimin Shen

https://doi.org/10.4081/ejh.2025.4241

519

PDF: 396

HTML: 8

Expression of bone morphogenetic protein signaling pathway players in the jejunum and colon of adult rats

Emma Cogo, Edwin Fouché, Charline Buisson, Adenike Omotoyinbo, Fabrice Pierre, Françoise Guéraud, Pascale Plaisancié

https://doi.org/10.4081/ejh.2025.4174

581

PDF: 365

HTML: 21

Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou

https://doi.org/10.4081/ejh.2025.4228

1185

PDF: 551

HTML: 18

Histological and histochemical characterization of the musk gland in forest musk deer (Moschus berezovskii): a preliminary study

Qianyi Wang, Chunyu Han, Dong Zhang, Yuning Liu, Yunyun Gao, Haolin Zhang, Defu Hu

https://doi.org/10.4081/ejh.2025.4216

609

PDF: 338

HTML: 41

NR4A3 suppresses bladder cancer progression by modulating autophagy via the PI3K/AKT/mTOR pathway

Li Fan, Feng Xu, Shouyong Liu, Ding Wu, Suchun Wang, Xin Pan, Yulin Zhou, Le Qu, Wenquan Zhou

https://doi.org/10.4081/ejh.2025.4221

904

PDF: 456

HTML: 17

Tanshinone IIA attenuates hepatic stellate cell activation, oxidative stress, and liver fibrosis by inhibiting YAP signaling

Dan Wang, Qingquan Tan, Qing Zheng, Yanling Ma, Li Feng

https://doi.org/10.4081/ejh.2025.4218

1333

PDF: 552

HTML: 26

E-cadherin inhibits the proliferation and migration of human colorectal cancer cells through Hippo signaling pathway

Zhijing Wang, Xiaohua Qin, Shanshan Liu, Yilei Wen, Bikan Lan, Hantao Liao, Haixian Wei

https://doi.org/10.4081/ejh.2025.4196

1156

PDF: 514

HTML: 17

MiR-122-5p inhibits the epithelial mesenchymal transition of liver cancer cells by inducing hiPSCs to differentiate into hepatocyte-like cells

Qianzhe Xing, Yanjie Xu, Ying Luo, Chenglong Li, Peng Wang, Bin Kang, Chengjun Lu

https://doi.org/10.4081/ejh.2025.4190

745

PDF: 392

HTML: 31

Knockdown of miR-411-3p induces M2 macrophage polarization and promotes colorectal cancer progression by regulation of MMP7

Tianliang Bai, Ping Li, Yabin Liu, Bindan Cai, Gang Li, Wenbin Wang, Rui Yan, Xiangkui Zheng, Shangkun Du

https://doi.org/10.4081/ejh.2025.4178

888

PDF: 391

Supplementary: 49

HTML: 48

Effect of CDX2 on proliferation, invasion, migration, and apoptosis of duodenal cancer cells

Jun Pan, Yi Zhao, Yu Zhang, Yuhe Zhou, Fengxuan Zhang, Yitian Chen, Xiaoyuan Chu

https://doi.org/10.4081/ejh.2025.4203

737

PDF: 294

HTML: 51

Cancer cell-derived exosomal miR-34a inhibits the malignant progression of pancreatic adenocarcinoma cells by restraining the M2 polarization of macrophages

Kui Long, Xiang Kui, Qingbin Zeng, Wenzhi Dong

https://doi.org/10.4081/ejh.2025.4176

1372

PDF: 605

Supplementary: 109

HTML: 44

Downregulation of S100 calcium-binding A4 (S100A4) ameliorates hepatic fibrosis via regulating Wnt/β-catenin signaling pathway

Chixian Zhang, Kai Bai, Dexu Li

https://doi.org/10.4081/ejh.2025.4186

1290

PDF: 474

HTML: 29

Independent and interactive roles of hirudin and HMGB1 interference in protecting renal function by regulating autophagy, apoptosis, and kidney injury in chronic kidney disease

Ying Li, Xuan Gao, Yao Chen, Huihui Li, Jing Tang, Wei Sun

https://doi.org/10.4081/ejh.2025.4182

1177

PDF: 706

HTML: 45

miR-627-5p inhibits malignant progression of cervical cancer by targeting ANGPTL4

Xinghua Wu, Kai Lin, Chen Gao, Yinfang Ni, Li Zhang, Tailai Yang, Jinguo Chen

https://doi.org/10.4081/ejh.2025.4161

1472

PDF: 471

HTML: 26

Co-expression of MyHC-15 with other known isoforms in rat muscle spindles

Vika Smerdu, Chiedozie Kenneth Ugwoke, Žiga Šink

https://doi.org/10.4081/ejh.2025.4192

1370

PDF: 328

HTML: 17

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