Original Papers
Vol. 47 No. 2 (2003)
https://doi.org/10.4081/819

Parkia pendula lectin as histochemistry marker for meningothelial tumour

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Published: 26 June 2009
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EIC Beltrão
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PL Medeiros
OG Rodrigues
J Figueredo-Silva
MM Valença
LCBB Coelho
LB Carvalho
Lectins have been intensively used in histochemical techniques for cell surface characterization. These proteins are involved in several biological processes and their use as histochemical markers have been evaluated since they can indicate differences in cell surfaces. Parkia pendula lectin (PpeL) was evaluated as histochemical marker for meningothelial meningioma biopsies. Tissue slices were incubated with PpeL conjugated to horseradish peroxidase (PpeL-HRP) and Concanavalin A-HRP (ConA-HPR) and the binding visualized with diaminobenzidine and hydrogen peroxide. The lectin-tissue binding was inhibited with D-glucose. PpeL showed to be a useful tool for the characterization of meningothelial tumour and clinico-pathological diagnosis.

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1.
Beltrão E, Medeiros P, Rodrigues O, Figueredo-Silva J, Valença M, Coelho L, et al. Parkia pendula lectin as histochemistry marker for meningothelial tumour. Eur J Histochem [Internet]. 2009 Jun. 26 [cited 2026 Apr. 30];47(2):139-42. Available from: https://www.ejh.it/ejh/article/view/819