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HACAT CELLS AS A 2D EXPERIMENTAL DIFFERENTIATING MODEL TO ANALYZE THE EARLY BIOLOGICAL EFFECTS INDUCED BY A PSORIATIC PROINFLAMMATORY MICROENVIRONMENT: CELL PROLIFERATION, DIFFERENTIATION AND FERROPTOSIS F. Riva1, S. Recalcati2, E. Gammella2, D. Daluiso1, F. Prignano3, E. Donetti2 | 1Dept. Public Health, Experimental and Forensic Medicine; Histology and Embryology Unit, University of Pavia, Pavia, Italy; 2Dept. Biomedical Sciences for Health, University of Milan, Milan, Italy; 3Dept. Health Sciences, Section of Dermatology, University of Florence, Florence, Italy
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P21 | EARLY BIOLOGICAL EFFECTS ON CELL PROLIFERATION AND DIFFERENTIATION INDUCED BY EXTRACELLULAR MICROVESICLES (EVS) DERIVED FROM HUMAN KERATINOCYTES IN PSORIATIC MICROENVIRONMENT D. Daluiso1, B. Barco1, C. Porro2, E. Donetti3, F. Riva1 | 1Department of Publich Health, Experimental and Forensic Medicine, Histology and Embryology Unit, University of Pavia, Pavia, Italy; 2Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy; 3Department of Biomedical Sciences for Health, University of Milan, Milan, Italy
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49 | TWEEN 60-COATED COPPER NANOPARTICLES FOR BIOMEDICAL APPLICATION: CHARACTERIZATION AND IN VITRO EVALUATION S. Mariano1|2, S.C. Resta3, G.C. Carbone1|2, A. Talà3, D. Manno1|2, A. Serra1|2, G. Quarta1|2, E. Panzarini3, L. Calcagnile1|2 | 1Department of Mathematics and Physics, University of Salento, Lecce, Italy; 2CEDAD (Center of Applied Physics, Datation and Diagnostics), Department of Mathematics and Physics, University of Salento, Lecce, Italy; 3Department of Biological and Environmental Sciences and Technologies (Di.S.Te.B.A.), University of Salento, Lecce, Italy
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P20 | SE4SAFE: A ONE HEALTH APPROACH TO ASSESS THE SAFETY OF BIOGENIC SELENIUM NANOPARTICLES A. Mileo1, S. Boccia2, B Sgangarella Valvano3, T. Pannulo4, F. Esposito4, L. Saviano4, G. Libralato4, M. De Falco4 | 1Dept. of Life Sciences, Health and Health Professions, Link Campus University, Rome, Italy; 2Dept. of Mental and Physical Health and Preventive Medicine, University of Campania “Luigi Vanvitelli”, Naples, Italy; 3Dept. of Medicine and Health Sciences “Vincenzo Tiberio”, University of Molise, Campobasso, Italy; 4Dept. of Biology, University of Naples Federico II, Naples, Italy
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23 | BIOFUNCTIONALIZED ELECTROSPUN FIBERS FOR SKIN REGENERATION E. Coccia1, R. Imperatore1, E. Mula1|2, M. Paolucci1 | 1Dept. of Sciences and Technologies, University of Sannio, Benevento, Italy; 2Dept. of Organic and Inorganic Chemistry, University of Alcalà, Alcalà de Henares, Spain
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P70 | TRICHOSANTHIN TARGETS WNT/NF-KB PATHWAYS TO ATTENUATE PSORIATIC INFLAMMATION AND KERATINOCYTE HYPERPROLIFERATION K. Wang1, W. Li1, Z. Ying1, C. Li2, O. Sha1 | 1Department of Anatomy and Histology, School of Basic Medical Sciences, Shenzhen University Medical School, Shenzhen, China; 2Department of Anatomy, Shantou University Medical College, Shantou, China
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