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P48 | NEW STRATEGIES TO IMPROVE THE RESPONSE OF AML CELLS TO TARGETED THERAPIES BY OVERCOMING THE PROTECTIVE EFFECT OF THE BONE MARROW MESENCHYMAL STEM CELLS G. Mazzanti1, F. Liccardo2, L. Pace1, M. Marcotulli3, L. Lafrate3, G. Cidonio3, T. Ottone4, S. Travaglini4, M.T. Voso4, V. Fulci5, M. Sampaolesi1, F. Fazi1, S. Masciarelli1 | 1Department of Anatomical, Histological, Forensic Medicine and Orthopedics Sciences and Medical Embryology, Section of Histology Sapienza University of Rome, Rome, Italy; 2Centre de Recherches en Cancérologie de Toulouse, Inserm/ U1037, Université de Toulouse, Toulouse, France; 3Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, Rome, Italy; 4Department of Biomedicine and Prevention, University of Tor Vergata, Rome, Italy; 5Department of Molecular Medicine, Sapienza, University of Rome, Rome, Italy
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P16 | A 3D IN VITRO MODEL TO STUDY CAF PLASTICITY AND TUMOR-STROMA INTERACTIONS IN OVARIAN CANCER P. Chiodelli1, J. Romoli1, P. Bonassi Signoroni2, E. Vertua2, C. Ferrari3, E. Giuzzi2, A. Paini2, E. Scalvini2, A. Papait1, F.R. Stefani2, A. R. Silini2, O. Parolini1 | 1Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy; 2Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy; 3Research and Clinical Trials Unit, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy
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P50 | OPTIMIZATION OF A RAPID AND EFFICIENT DECELLULARIZATION PROTOCOL FOR COMPOSITE VASCULARIZED FACIAL GRAFT FABRICATION A. Menini1, A. M. Sacco1, V. Romano1, D. Nurzynska2, G. Ricci3, S. La Padula1, F. Schonauer1, C. Castaldo1, F. Di Meglio1 | 1Department of Public Health, University of Naples «Federico II», Naples, Italy; 2Department of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, Italy; 3Department of Experimental Medicine, University of Campania «Luigi Vanvitelli», Naples, Italy
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63 | EVOLUTIONARY STRATEGIES OF CARDIAC GROWTH: THE ICEFISH HEART AS A MODEL TO CONTRAST PATHOLOGICAL CELLULAR MALADAPTATION N. Romano1, R. Gaetani2, M. Gerdol3, C. Bidoli3, M. Mercola4 E. Messina2 | 1Dept. of Life Sciences, Health and Health Professions, Link Campus University, Rome, Italy; 2Dept. of Molecular Medicine, Sapienza University, Rome, Italy; 3Dept. of Life Sciences, University of Trieste, Italy; 4Dept. of Medicine and Cardiovascular Institute, Stanford University, Palo Alto, CA, USA
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P20 | RNASEQ AND HISTOCHEMICAL STAININGS ASSESS BIOCHEMICAL AND STRUCTURAL CHANGES IN THE MOUSE INTERVERTEBRAL DISC ACROSS THE LIFESPAN A. Hallmark1, A. Ali2, C. Dahia3 | 1Hospital for Special Surgery, New York, USA; 2Department of Medicine, Columbia University, New York, USA; 3Hospital for Special Surgery, Weill Cornell Medicine
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OVEREXPRESSION OF ANOSMIN-1 ALTERS THE MYELINATION PATTERN AND THE MORPHOLOGY OF AXONAL COMPONENTS IN CEREBELLAR PURKINJE CELLS Fieromonte A1, Lorenzati M1, Staffa A2, Bribian A2, Barderas MG3, Aguilar J4, De Castro F2 and Buffo A1 | 1Neuroscience Institute Cavalieri Ottolenghi (NICO), University of Turin, Department of Neuroscience ita Levi, Montalcini, Turin, Italy; 2Instituto Cajal-CSIC, Grupo de Neurobiologia del Desarrollo-GNDe, Madrid, Spain; 3Servicio de Salud de Castilla- La Mancha-SESCAM, Department of Vascular Physiopathology, Hospital Nacional de Paraplejicos, Toledo, Spain; 4Servicio de Salud de Castilla-La Mancha-SESCAM, Experimental Neurophysiology Group, Hospital Nacional de Paraplejicos, Toledo, Spain
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Histological and Histochemical Methods - Theory and practice
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