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  Knockdown of ARHGAP30 inhibits ovarian cancer cell proliferation, migration, and invasiveness by suppressing the PI3K/AKT/mTOR signaling pathway

  Xiaoyan Chu, Jun Lou, Yun Yi, Linlin Zhong, Ouping Huang

  11-05-2023

  https://doi.org/10.4081/ejh.2023.3653

  1146

  PDF: 602

  HTML: 38
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  NR4A3 suppresses bladder cancer progression by modulating autophagy via the PI3K/AKT/mTOR pathway

  Li Fan, Feng Xu, Shouyong Liu, Ding Wu, Suchun Wang, Xin Pan, Yulin Zhou, Le Qu, Wenquan Zhou

  30-06-2025

  https://doi.org/10.4081/ejh.2025.4221

  766

  PDF: 408

  HTML: 15
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  microRNA-16-5p suppresses cell proliferation and angiogenesis in colorectal cancer by negatively regulating forkhead box K1 to block the PI3K/Akt/mTOR pathway

  Xin Huang, Xuan Xu, Huajing Ke, Xiaolin Pan, Jiaoyu Ai, Ruyi Xie, Guilian Lan, Yang Hu, Yao Wu

  10-05-2022

  https://doi.org/10.4081/ejh.2022.3333

  1675

  PDF: 890

  HTML: 28
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  Correlation of the AKT/mTOR signaling pathway with the clinicopathological features and prognosis of nasopharyngeal carcinoma

  Yan Wang, Jie Sun, Ninghua Yao

  16-11-2021

  https://doi.org/10.4081/ejh.2021.3304

  1646

  PDF: 605

  HTML: 38
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  Study on the mechanism of Shenling Baizhu powder on the pathogenesis of pregnancy complicated with non-alcoholic fatty liver, based on PI3K/AKT/mTOR signal pathway

  Yao Le, Zhijun Wang, Qian Zhang, Ling Miao, Xiaohong Wang, Guorong Han

  17-09-2024

  https://doi.org/10.4081/ejh.2024.4093

  2216

  PDF: 576

  HTML: 49
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  Downregulation of Williams syndrome transcription factor (WSTF) suppresses glioblastoma cell growth and invasion by inhibiting PI3K/AKT signal pathway

  Liyuan Yang, Chunfu Du, Hui Chen, Zhengwen Diao

  17-11-2021

  https://doi.org/10.4081/ejh.2021.3255

  1181

  PDF: 622

  HTML: 42

• P25 | RESPONSE TO HEDGEHOG AND PI3K/AKT/MTOR PATHWAY INHIBITORS IN PREB-ALL: ANALYSIS OF THE INTRACELLULAR DISTRIBUTION OF PATHWAY ENZYMES AND OF THE AUTOPHAGY PROCESS M. Sicurella¹, M. De Chiara², E. Battaglia², F. Franco², M. De Vita², L.M. Neri² | ¹Department of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy; ²Department of Translational Medicine, University of Ferrara, Ferrara, Italy

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4345

  187
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  Effects of Notch signaling on proliferation, angiogenesis, and adipogenesis of hemangioma-derived stem cells

  Weidong Wang, Sheng Chen, Yuan Wang, Cui Jie, Weimin Shen

  01-09-2025

  https://doi.org/10.4081/ejh.2025.4241

  487

  PDF: 376

  HTML: 6
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  SUSD2 suppresses lung adenocarcinoma tumorigenesis by inducing autophagy via inhibiting PI3K/AKT/mTOR signaling pathway

  Shengwen Wang, Gang Yang, Qian Zhang, Yanbei Zhang

  18-05-2026

  https://doi.org/10.4081/ejh.2026.4544

  68

  PDF: 44

  Supplementary: 2
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  Extracellular vesicles from bone mesenchymal stem cells transport microRNA-206 into osteosarcoma cells and target NRSN2 to block the ERK1/2-Bcl-xL signaling pathway

  Alimu Keremu, Pazila Aila, Aikebaier Tusun , Maimaitiaili Abulikemu, Xiaoguang Zou

  22-06-2022

  https://doi.org/10.4081/ejh.2022.3394

  1878

  PDF: 1249

  HTML: 27
• 

  Significance and relationship between DJ-1 gene and survivin gene expression in laryngeal carcinoma

  Z. Shen, Y. Ren, D. Ye, J. Guo, C. Kang, H. Ding

  e9

  21-03-2011

  https://doi.org/10.4081/ejh.2011.e9

  1753

  PDF: 503

  HTML: 1691
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  Immunohistochemical expression and clinicopathological assessment of PD-1, PD-L1, NY-ESO-1, and MAGE-A4 expression in highly aggressive soft tissue sarcomas

  Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Ryosuke Kakinoki, Masao Akagi

  22-04-2022

  https://doi.org/10.4081/ejh.2022.3393

  1255

  PDF: 704

  HTML: 23
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  DPY30 promotes the growth and survival of osteosarcoma cell by regulating the PI3K/AKT signal pathway

  Gong Cheng, Fengmin An, Zhilin Cao, Mingdi Zheng, Zhongyuan Zhao, Hao Wu

  22-12-2022

  https://doi.org/10.4081/ejh.2023.3413

  1212

  PDF: 626

  Supplementary: 96

  HTML: 26
• 

  Pretreatment with geniposide mitigates myocardial ischemia/reperfusion injury by modulating inflammatory response through TLR4/NF-κB pathway

  Yanmei Yao, Leqing Lin, Wenxue Tang, Yueliang Shen, Fayu Chen, Ning Li, Baiyong Wang

  08-09-2023

  https://doi.org/10.4081/ejh.2023.3742

  1075

  PDF: 469

  HTML: 20
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  Long noncoding RNA Meg3 mediates ferroptosis induced by oxygen and glucose deprivation combined with hyperglycemia in rat brain microvascular endothelial cells, through modulating the p53/GPX4 axis

  Cheng Chen, Yan Huang, Pingping Xia, Fan Zhang, Longyan Li, E Wang, Qulian Guo, Zhi Ye

  30-09-2021

  https://doi.org/10.4081/ejh.2021.3224

  3427

  PDF: 1860

  HTML: 38

• P37 | THE ROLE OF ACTIN-BINDING PROTEINS IN ENDOMETRIOSIS W. Arendt¹, M. Hałas-Wiśniewska¹, M. Gagat², M. Izdebska¹ | ¹Department of Histology and Embryology, Faculty of Medicine, Nicolaus Copernicus University in Toruń, Collegium Medicum in Bydgoszcz, Poland; ²Department of Histology and Embryology, Faculty of Medicine, Nicolaus Copernicus University in Toruń, Collegium Medicum in Bydgoszcz, Poland; Faculty of Medicine, Collegium Medicum, Mazovian Academy in Płock, Poland

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4359

  187
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  Quercetin reverses 5-fluorouracil resistance in colon cancer cells by modulating the NRF2/HO-1 pathway

  Zhongzhu Tang, Lei Wang, Yunwang Chen, Xiaomin Zheng, Runyu Wang, Bingxue Liu, Shiqi Zhang, Huimin Wang

  07-08-2023

  https://doi.org/10.4081/ejh.2023.3719

  1719

  PDF: 862

  HTML: 22
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  Therapeutic effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles on ovarian functions through the PI3K/Akt cascade in mice with premature ovarian failure

  Nan Li, Xue Fan, Lihong Liu, Yanbing Liu

  27-07-2023

  https://doi.org/10.4081/ejh.2023.3506

  1658

  PDF: 1016

  HTML: 21
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  Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

  Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou

  06-08-2025

  https://doi.org/10.4081/ejh.2025.4228

  1076

  PDF: 493

  HTML: 17
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  LncRNA FBXO18-AS promotes gastric cancer progression by TGF-β1/Smad signaling

  Yiming Zhang, Wanqiong Zheng, Liang Zhang, Yechun Gu, Lihe Zhu, Yingpeng Huang

  20-06-2023

  https://doi.org/10.4081/ejh.2023.3667

  1150

  PDF: 612

  Supplementary: 87

  HTML: 20
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  MicroRNA-17-3p is upregulated in psoriasis and regulates keratinocyte hyperproliferation and pro-inflammatory cytokine secretion by targeting CTR9

  Qingwen Li, Jiao Zhang, Shougang Liu, Fangfei Zhang, Jiayi Zhuang, Yongfeng Chen

  12-01-2022

  https://doi.org/10.4081/ejh.2022.3275

  1905

  PDF: 792

  Supplementary: 146

  HTML: 34
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  Astragaloside IV augments anti-PD-1 therapy to suppress tumor growth in lung cancer by remodeling the tumor microenvironment

  Tao Wu, Shikui Wu, Hui Gao, Haolei Liu, Jun Feng, Ge Yin

  23-10-2024

  https://doi.org/10.4081/ejh.2024.4098

  2164

  PDF: 460

  HTML: 27
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  Overexpression of GPER1 suppressed esophageal carcinoma growth via activating cAMP pathway

  Hongmei Yin, Xiumei Han, Qun Zhang, Duojie Li, Fan Wang

  26-01-2026

  https://doi.org/10.4081/ejh.2026.4422

  590

  PDF: 333

  Supplementary: 41

  Original gels: 38

  HTML: 10
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  The Qi-Bang-Yi-Shen formula ameliorates renal dysfunction and fibrosis in rats with diabetic kidney disease via regulating PI3K/AKT, ERK and PPARγ signaling pathways

  Zhi Wang, Guihua Jian, Teng Chen, Yiping Chen, Junhui Li, Niansong Wang

  01-03-2023

  https://doi.org/10.4081/ejh.2023.3648

  3057

  PDF: 1037

  HTML: 43