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Quantitative, structural and molecular changes in neuroglia of aging mammals: A review

Ennio Pannese

23-06-2021

https://doi.org/10.4081/ejh.2021.3249

1991

PDF: 984

HTML: 51
Propofol alleviates M1 polarization and neuroinflammation of microglia in a subarachnoid hemorrhage model in vitro, by targeting the miR-140-5p/TREM-1/NF-κB signaling axis

Lan Wang, Zhenyu Fan, Haijin Wang, Shougui Xiang

17-09-2024

https://doi.org/10.4081/ejh.2024.4034

1510

PDF: 848

HTML: 49
Ghrelin reduces cerebral ischemic injury in rats by reducing M1 microglia/macrophages

Rong Tian, Gengsheng Mao

12-01-2022

https://doi.org/10.4081/ejh.2022.3350

2006

PDF: 1105

HTML: 74
Changes in cytoplasmic and extracellular neuromelanin in human substantia nigra with normal aging

Dmitrii E. Korzhevskii, Olga V. Kirik, Valeriia V. Guselnikova, Darya L. Tsyba, Elena A. Fedorova, Igor P. Grigorev

01-09-2021

https://doi.org/10.4081/ejh.2021.3283

2221

PDF: 821

HTML: 50
Spatio-temporal course of macrophage-like cell accumulation after experimental embolic stroke depending on treatment with tissue plasminogen activator and its combination with hyperbaric oxygenation

D. Michalski, M. Heindl, J. Kacza, F. Laignel, L. KÃ¼ppers-Tiedt, D. Schneider, J. Grosche, J. Boltze, M. LÃ¶hr, C. Hobohm, W. HÃ¤rtig

e14

09-05-2012

https://doi.org/10.4081/ejh.2012.14

6979

PDF: 951

HTML: 10680
PDTC ameliorates neuropathic pain by inhibiting microglial activation via blockage of the TNFα-CX3CR1 pathway

Xilei Li, Zhi Ye, Qulian Guo, E Wang, Yundan Pan

12-03-2021

https://doi.org/10.4081/ejh.2021.3184

2458

PDF: 1069

HTML: 55
Dexmedetomidine attenuates neuroinflammation and microglia activation in LPS-stimulated BV2 microglia cells through targeting circ-Shank3/miR-140-3p/TLR4 axis

Guangbao He, Yibo He, Hongwei Ni, Kai Wang, Yijun Zhu, Yang Bao

26-07-2023

https://doi.org/10.4081/ejh.2023.3766

2527

PDF: 1538

HTML: 49
Ion channels alterations in the forebrain of high-fat diet fed rats

Proshanta Roy, Ilenia Martinelli, Michele Moruzzi, Federica Maggi, Consuelo Amantini, Maria Vittoria Micioni Di Bonaventura, Carlo Cifani, Francesco Amenta, Seyed Khosrow Tayebati, Daniele Tomassoni

23-11-2021

https://doi.org/10.4081/ejh.2021.3305

2433

PDF: 1273

HTML: 76
Antioxidant support to ameliorate the oxaliplatin-dependent microglial alteration: morphological and molecular study

Jacopo J.V. Branca, Donatello Carrino, Ferdinando Paternostro, Massimo Gulisano, Matteo Becatti, Lorenzo Di Cesare Mannelli, Alessandra Pacini

10-11-2021

https://doi.org/10.4081/ejh.2021.3285

1656

PDF: 907

HTML: 45
The role of mutated SOD1 gene in synaptic stripping and MHC class I expression following nerve axotomy in ALS murine model

Roman M. Kassa, Roberta Bonafede, Federico Boschi, Manuela Malatesta, Raffaella Mariotti

17-05-2018

https://doi.org/10.4081/ejh.2018.2904

2425

PDF: 849

HTML: 57
3-hydroxi-anthranilic acid is early expressed in stroke

A. Mangas, J. Yajeya, N. González, I. Ruiz, M. Geffard, R. Coveñas

02-12-2016

https://doi.org/10.4081/ejh.2016.2709

2616

PDF: 848

HTML: 352
Gemst: a taylor-made combination that reverts neuroanatomical changes in stroke

Arturo Mangas, Javier Yajeya, Noelia González, Isabel Ruiz, Marianny Pernía, Michel Geffard, Rafael Coveñas

25-05-2017

https://doi.org/10.4081/ejh.2017.2790

2146

PDF: 829

HTML: 232
Microglia of teleosts: facing a challenge in neurobiology

B Cuoghi, L Mola

231-240

10-08-2009

https://doi.org/10.4081/1147

683

PDF: 1284
Overexpression of kynurenic acid and 3-hydroxyanthranilic acid after rat traumatic brain injury

Arturo Mangas, Margarita Heredia, Adelaida Riolobos, Antonio de la Fuente, José María Criado, Javier Yajeya, Michel Geffard, Rafael Coveñas

14-11-2018

https://doi.org/10.4081/ejh.2018.2985

2508

PDF: 933

HTML: 62
Glyphosate, AMPA and glyphosate-based herbicide exposure leads to GFAP, PCNA and caspase-3 increased immunoreactive area on male offspring rat hypothalamus

Ewing Duque-Díaz, Hernán Hurtado Giraldo, Linda P. Rocha-Muñoz, Rafael Coveñas

13-10-2022

https://doi.org/10.4081/ejh.2022.3428

2325

HTML: 102

PDF: 977
miR-132 regulates the expression of synaptic proteins in APP/PS1 transgenic mice through C1q

Nan Xu, Ang-Di Li, Li-Li Ji, Yao Ye, Zhen-Yu Wang, Lei Tong

03-05-2019

https://doi.org/10.4081/ejh.2019.3008

3108

PDF: 1422

HTML: 56
Immunohistochemical markers of neural progenitor cells in the early embryonic human cerebral cortex

L. Vinci, A. Ravarino, V. Fanos, A.G. Naccarato, G. Senes, C. Gerosa, G. Bevilacqua, G. Faa, R. Ambu

01-02-2016

https://doi.org/10.4081/ejh.2016.2563

5062

PDF: 2631

HTML: 1674
Immunohistochemical demonstration of specific antigens in the human brain fixed in zinc-ethanol-formaldehyde

D.E. Korzhevskii, E.G. Sukhorukova, O.V. Kirik, I.P. Grigorev

05-08-2015

https://doi.org/10.4081/ejh.2015.2530

3047

PDF: 1034

HTML: 1413
ECRG4 expression in normal rat tissues: expression study and literature review

A. Porzionato, M. Rucinski, V. Macchi, G. Sarasin, L.K. Malendowicz, R. De Caro

18-05-2015

https://doi.org/10.4081/ejh.2015.2458

3312

PDF: 1337

Supplementary: 504

HTML: 1059
NEUROBIOLOGY OF SUICIDE: MORPHOLOGICAL ASSESSMENT OF MICROGLIAL NETWORK IN HUMAN POST-MORTEM PREFRONTAL CORTEX Tambuzzi S¹, Bertolotto N², Massari S², Madaschi L³, Alini M², Brandolese D², Ubezio MC¹, Cattaneo C¹ and Amadeo A² | ¹Institute of Forensic Medicine, Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy; ²Department of Biosciences, Università degli Studi di Milano, Milan, Italy; ³UNITECH NOLIMITS, Università degli Studi di Milano, Milan, Italy

12-12-2025

https://doi.org/10.4081/ejh.2025.4459

470
GLIAL INFLAMMASOME ACTIVATION AND BLOOD-BRAIN BARRIER BREAKDOWN IN AGE-RELATED NEURODEGENERATION Errede M¹, Girolamo F¹, d’Amati A^1,2, de Giorgis M¹, Lorusso L¹, Pierucci C³, Bernardini N³, Pellegrini C³, Virgintino D¹ and Annese T² | ¹University of Bari, Department of Translational Biomedicine and Neuroscience – Human Anatomy and Histology Unit, Bari, Italy; ²Libera Università del Mediterraneo (LUM) Giuseppe Degennaro University, Department of Medicine and Surgery, Bari, Italy; ³University of Pisa, Department of Clinical and Experimental Medicine - Unit of Histology and Medical Embryology, Pisa, Italy

12-12-2025

https://doi.org/10.4081/ejh.2025.4460

668
Bradykinin and noradrenaline preconditioning influences level of antioxidant enzymes SOD, CuZn-SOD, Mn-SOD and catalase in the white matter of spinal cord in rabbits after ischemia/reperfusion

Marianna Danková, Iveta Domoráková, Zuzana Fagová, Milan Stebnický, Alexandra Kunová, Eva Mechírová

18-10-2019

https://doi.org/10.4081/ejh.2019.3045

1862

PDF: 827

HTML: 54
Effects of piperlonguminine on lung injury in severe acute pancreatitis via the TLR4/NF-κB pathway

Qian Hu, Ran Tao, Xiaoyun Hu, Haibo Wu, Jianjun Xu

20-03-2023

https://doi.org/10.4081/ejh.2023.3639

1481

PDF: 894

HTML: 58
P01 | BET PROTEIN INHIBITION ATTENUATES MICROGLIAL ACTIVATION AND OXIDATIVE STRESS IN A CELLULAR MODEL OF PARKINSON’S DISEASE E. Bisesto¹, D. Pensabene¹, M. Colardo¹, M. Varone¹, M. Segatto¹ | ¹Dept. of Biosciences and territory, University of Molise, Pesche (IS), Italy

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

https://doi.org/10.4081/ejh.2026.4697

165

PDF: 97
Galunisertib enhances chimeric antigen receptor-modified T cell function

Zhixiong Wang, Qian Liu, Na Risu, Jiayu Fu, Yan Zou, Jiaxing Tang, Long Li, Hui Liu, Guomin Zhou, Xuekai Zhu

19-06-2020

https://doi.org/10.4081/ejh.2020.3122

2291

PDF: 1220

Supplementary: 232

HTML: 49
P13 | MORPHO-FUNCTIONAL DIFFERENCES IN THE GUT OF AGED MICE WITH THE POSSIBLE EFFECTS OF ANTI-INFLAMMATORY TREATMENTS A. Casini¹, S. Leone¹, R. Mancinelli¹, R. Vaccaro¹, M. Catalano², G. D’Alessandro², A. Rinaldi², A. Reccagni², G. Vivacqua³, A. Franchitto⁴, P. Onori¹, C. Limatola², E. Gaudio¹ | ¹Department of Anatomical, Histological, Forensic Medicine and Orthopaedics Sciences, Sapienza University of Rome, Italy; ²Department of Physiology and Pharmacology, Sapienza University of Rome, Italy; ³Department of Medicine and Surgery, University Campus BioMedico of Rome, Italy; ⁴Department of Movement, Human and Health Sciences, Division of Health Sciences, University of Rome «Foro Italico», Rome,Italy

21-08-2025

https://doi.org/10.4081/ejh.2025.4333

253
P30 | P75NTR MODULATION IMPROVES RESILIENCE TO OXIDATIVE DAMAGE IN A MICROGLIAL CELL MODEL OF PARKINSON’S DISEASE A. Valenza¹, D. Pensabene², F. Rendina¹, M. Muzzi², A. Fracassi³, M. Segatto², S. Moreno^1|3 | ¹Dept. of Science, University Roma Tre, Rome, Italy; ²Dept. of Biosciences and Territory, University of Molise, Pesche, Italy; ³Dept. of Neurology, UTMB, Galveston, TX, USA

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

https://doi.org/10.4081/ejh.2026.4726

201

PDF: 111
Antigen retrieval pre-treatment causes a different expression pattern of Cav3.2 in rat and mouse spinal dorsal horn

Xiao E Cheng, Long Xian Ma, Xiao Jin Feng, Meng Ye Zhu, Da Ying Zhang, Lin Lin Xu, Tao Liu

23-01-2019

https://doi.org/10.4081/ejh.2019.2988

2335

PDF: 1034

Supplementary: 319

HTML: 70
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model

Juan Fan, Yu Ma, Liying Sun, Suhua Miao, Jianghong He

20-04-2026

https://doi.org/10.4081/ejh.2026.4533

919

PDF: 447

HTML: 58
miR-19a targeting CLCA4 to regulate the proliferation, migration, and invasion of colorectal cancer cells

Huiwen Li, Bo Huang

10-03-2022

https://doi.org/10.4081/ejh.2022.3381

2449

PDF: 871

HTML: 61
Co-transplantation of bone marrow mesenchymal stem cells and monocytes in the brain stem to repair the facial nerve axotomy

Li Wu, Dan Han, Jie Jiang, Xiaojie Xie, Xunran Zhao, Tengfei Ke, Wen Zhao, Liu Liu, Wei Zhao

19-06-2020

https://doi.org/10.4081/ejh.2020.3136

1887

PDF: 921

HTML: 50
Neurodegeneration in zebrafish embryos and adults after cadmium exposure

Antonio Monaco, Teresa Capriello, Maria C. Grimaldi, Valentina Schiano, Ida Ferrandino

19-10-2017

https://doi.org/10.4081/ejh.2017.2833

3680

PDF: 1460

HTML: 178
The possible alleviating effect of garlic supplement on the neural retina in a rat model of hypercholesterolemia: a histological and immunohistochemical study

Eetmad A. Arafat, Eman M.I. Youssef, Hanaa A. Khalaf

16-12-2021

https://doi.org/10.4081/ejh.2021.3322

1495

PDF: 745

HTML: 52
Immunohistochemical detection of acth and msh cells in the hypophysis of the hermaphroditic teleost, Diplodus sargus

I Ferrandino, A Pica, M Consiglio Grimaldi

397-406

23-12-2009

https://doi.org/10.4081/ejh.2000.1604

175

PDF: 81
Sinensetin ameliorates osteoarthritis progression by modulating the NF-κB/NLRP3 signaling pathway and suppressing chondrocyte pyroptosis

Zhendong Liu, Ruizhou Liu, Hongwei Yue, Peilai Liu, Rui Wang

07-10-2026

https://doi.org/10.4081/ejh.2026.4587

803

PDF: 244

HTML: 3
Imaging techniques in nanomedical research

Laura Calderan, Manuela Malatesta

01-07-2020

https://doi.org/10.4081/ejh.2020.3151

2353

PDF: 944

HTML: 56
Immunohistochemical analysis of YB-1 expression in the developing mouse eye

Alexander Forian Nass, Hella Wolf, Saadettin Sel , Thomas Kalinski, Norbert Nass

03-11-2025

https://doi.org/10.4081/ejh.2025.4244

2136

PDF: 366

HTML: 64
Long noncoding RNA Meg3 mediates ferroptosis induced by oxygen and glucose deprivation combined with hyperglycemia in rat brain microvascular endothelial cells, through modulating the p53/GPX4 axis

Cheng Chen, Yan Huang, Pingping Xia, Fan Zhang, Longyan Li, E Wang, Qulian Guo, Zhi Ye

30-09-2021

https://doi.org/10.4081/ejh.2021.3224

4054

PDF: 2060

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Expressions of TLR4, MyD88, IRAK4 and NF-κΒ in the oviduct of Chinese brown frog (Rana dybowskii)

Yue Zhang, Ao Zhang, Yue Zhao, Xiaohang Feng, Yuyao Sheng, Haolin Zhang, Qiang Weng, Meiyu Xu

25-09-2019

https://doi.org/10.4081/ejh.2019.3050

1272

PDF: 679

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Effects of cadmium on the glial architecture in lizard brain

Rossana Favorito, Antonio Monaco, Maria C. Grimaldi, Ida Ferrandino

23-01-2017

https://doi.org/10.4081/ejh.2017.2734

3367

PDF: 927

HTML: 399
P06 | MODELING THE COMPLEXITY OF THE CENTRAL NERVOUS SYSTEM WITH PATIENT IPSC-DERIVED CEREBRAL ORGANOIDS L. Carpinelli¹, D. Sibilia¹, P.N. Doronzio², F. Giacalone¹, C. Lisciandrello², E. Guadagni², A. Conte³, S. Lattante⁴, M. Magatti⁵, A. Silini⁵, Facility Biobanca⁶, Facility Citometria a Flusso⁶, L. Di Pietro^1|2, M. Sabatelli³, O. Parolini^1|2 | ¹Fondazione Policlinico Universitario A. Gemelli IRCSS, Rome, Italy; ²Dipartimento di Scienze della Vita e Sanità Pubblica, Università Cattolica del Sacro Cuore, Rome, Italy; ³Centro Clinico NEMO, Fondazione Policlinico Gemelli IRCCS, Rome, Italy; ⁴Department of Experimental Medicine, University of Salento, Lecce, Italy; ⁵Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy; ⁶Gemelli Science and Technology Park (GSTeP), Fondazione Policlinico Universitario A. Gemelli IRCSS, Rome, Italy

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

https://doi.org/10.4081/ejh.2026.4702

141

PDF: 120
Sufentanil alleviates cerebral ischemia-reperfusion injury by inhibiting inflammation and protecting the blood-brain barrier in rats

Zhen Wang, Xiaoyan Du, Daoyang Yu, Yang Yang, Gaoen Ma, Xueli Jia, Lulu Cheng

12-01-2022

https://doi.org/10.4081/ejh.2022.3328

2490

PDF: 1469

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Immunoreactivity for thymosin beta 4 and thymosin beta 10 in the adult rat oro-gastro-intestinal tract

S. Nemolato, J. Ekstrom, T. Cabras, C. Gerosa, D. Fanni, E. Di Felice, A. Locci, I. Messana, M. Castagnola, G. Faa

e17

07-05-2013

https://doi.org/10.4081/ejh.2013.e17

2665

PDF: 919

HTML: 574
Visnagin ameliorates myocardial ischemia/reperfusion injury through the promotion of autophagy and the inhibition of apoptosis

Hai-rong Fu, Xiao-shan Li, Yong-hui Zhang, Bin-bin Feng, Lian-hong Pan

07-09-2020

https://doi.org/10.4081/ejh.2020.3131

1477

PDF: 1044

HTML: 42
Expression of S100β during mouse cochlear development

Wenjing Liu, Yongchun Zhang, Cheng Liang, Lizhong Su

10-03-2025

https://doi.org/10.4081/ejh.2025.4189

1666

PDF: 581

Supplementary: 130

HTML: 35
Cannabinoid CB2 receptors are involved in the protection of RAW264.7 macrophages against the oxidative stress: an in vitro study

Sabrina Giacoppo, Agnese Gugliandolo, Oriana Trubiani, Federica Pollastro, Gianpaolo Grassi, Placido Bramanti, Emanuela Mazzon

23-01-2017

https://doi.org/10.4081/ejh.2017.2749

6296

PDF: 1504

HTML: 440
Histochemical approaches to assess cell-to-cell transmission of misfolded proteins in neurodegenerative diseases

G. Natale, E. Pompili, F. Biagioni, S. Paparelli, P. Lenzi, F. Fornai

e5

07-03-2013

https://doi.org/10.4081/ejh.2013.e5

3542

PDF: 928

HTML: 234
Characterization of kynurenine pathway in patients with diarrhea-predominant irritable bowel syndrome

Pingping Li, Jimin Zheng, Yun Bai, Dingxin Wang, Zijin Cui, Yueqin Li, Jian Zhang, Yuzhen Wang

19-06-2020

https://doi.org/10.4081/ejh.2020.3132

2664

PDF: 1298

HTML: 58
Degenerative effects in rat eyes after experimental ocular hypertension

G. Scarsella, M. Nebbioso, S. Stefanini, N. Pescosolido

e42

08-10-2012

https://doi.org/10.4081/ejh.2012.e42

1762

PDF: 705

HTML: 233
Management of autofluorescence in formaldehyde-fixed myocardium: choosing the right treatment

Zhao Zhang, Hongming Fan, William Richardson, Bruce Z. Gao, Tong Ye

02-10-2023

https://doi.org/10.4081/ejh.2023.3812

2479

PDF: 1295

Supplementary: 178

HTML: 66
Gliocyte and synapse analyses in cerebral ganglia of the Chinese mitten crab, Eriocheir sinensis: ultrastructural study

H. Zhang, P. Yu, S. Zhong, T. Ge, S. Peng, Z. Zhou, X. Guo

10-08-2016

https://doi.org/10.4081/ejh.2016.2655

1898

PDF: 870

HTML: 446
miR-1270 enhances the proliferation, migration, and invasion of osteosarcoma via targeting cingulin

Yang Liu, Weichun Guo, Shuo Fang, Bin He, Xiaohai Li, Li Fan

07-12-2021

https://doi.org/10.4081/ejh.2021.3237

1976

PDF: 710

HTML: 65
Thrombin regulates the ability of Schwann cells to support neuritogenesis and to maintain the integrity of the nodes of Ranvier

Elena Pompili, Viviana Ciraci, Stefano Leone, Valerio De Franchis, Pietro Familiari, Roberto Matassa, Giuseppe Familiari, Ada Maria Tata, Lorenzo Fumagalli, Cinzia Fabrizi

30-03-2020

https://doi.org/10.4081/ejh.2020.3109

2288

PDF: 1035

HTML: 77

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