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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

1.9
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1.9
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3.7
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  • By Dchordpdx - Own work, CC BY 4.0, https://commons.wikimedia.org/w/index.php?curid=64427063

    Quantitative, structural and molecular changes in neuroglia of aging mammals: A review

    Ennio Pannese
    23-06-2021
    https://doi.org/10.4081/ejh.2021.3249
    1788
    PDF: 879
    HTML: 19
  • Propofol alleviates M1 polarization and neuroinflammation of microglia in a subarachnoid hemorrhage model in vitro, by targeting the miR-140-5p/TREM-1/NF-κB signaling axis

    Lan Wang, Zhenyu Fan, Haijin Wang, Shougui Xiang
    17-09-2024
    https://doi.org/10.4081/ejh.2024.4034
    1261
    PDF: 663
    HTML: 14
  • Ghrelin reduces cerebral ischemic injury in rats by reducing M1 microglia/macrophages

    Rong Tian, Gengsheng Mao
    12-01-2022
    https://doi.org/10.4081/ejh.2022.3350
    1853
    PDF: 929
    HTML: 42
  • Changes in cytoplasmic and extracellular neuromelanin in human substantia nigra with normal aging

    Dmitrii E. Korzhevskii, Olga V. Kirik, Valeriia V. Guselnikova, Darya L. Tsyba, Elena A. Fedorova, Igor P. Grigorev
    01-09-2021
    https://doi.org/10.4081/ejh.2021.3283
    2018
    PDF: 708
    HTML: 25
  • Spatio-temporal course of macrophage-like cell accumulation after experimental embolic stroke depending on treatment with tissue plasminogen activator and its combination with hyperbaric oxygenation

    D. Michalski, M. Heindl, J. Kacza, F. Laignel, L. Küppers-Tiedt, D. Schneider, J. Grosche, J. Boltze, M. Löhr, C. Hobohm, W. Härtig
    e14
    09-05-2012
    https://doi.org/10.4081/ejh.2012.14
    6760
    PDF: 852
    HTML: 10461
  • PDTC ameliorates neuropathic pain by inhibiting microglial activation via blockage of the TNFα-CX3CR1 pathway

    Xilei Li, Zhi Ye, Qulian Guo, E Wang, Yundan Pan
    12-03-2021
    https://doi.org/10.4081/ejh.2021.3184
    2244
    PDF: 938
    HTML: 21
  • Dexmedetomidine attenuates neuroinflammation and microglia activation in LPS-stimulated BV2 microglia cells through targeting circ-Shank3/miR-140-3p/TLR4 axis

    Guangbao He, Yibo He, Hongwei Ni, Kai Wang, Yijun Zhu, Yang Bao
    26-07-2023
    https://doi.org/10.4081/ejh.2023.3766
    2173
    PDF: 1381
    HTML: 21
  • Ion channels alterations in the forebrain of high-fat diet fed rats

    Proshanta Roy, Ilenia Martinelli, Michele Moruzzi, Federica Maggi, Consuelo Amantini, Maria Vittoria Micioni Di Bonaventura, Carlo Cifani, Francesco Amenta, Seyed Khosrow Tayebati, Daniele Tomassoni
    23-11-2021
    https://doi.org/10.4081/ejh.2021.3305
    2275
    PDF: 1155
    HTML: 45
  • Antioxidant support to ameliorate the oxaliplatin-dependent microglial alteration: morphological and molecular study

    Jacopo J.V. Branca, Donatello Carrino, Ferdinando Paternostro, Massimo Gulisano, Matteo Becatti, Lorenzo Di Cesare Mannelli, Alessandra Pacini
    10-11-2021
    https://doi.org/10.4081/ejh.2021.3285
    1492
    PDF: 812
    HTML: 18
  • The role of mutated SOD1 gene in synaptic stripping and MHC class I expression following nerve axotomy in ALS murine model

    Roman M. Kassa, Roberta Bonafede, Federico Boschi, Manuela Malatesta, Raffaella Mariotti
    17-05-2018
    https://doi.org/10.4081/ejh.2018.2904
    2150
    PDF: 757
    HTML: 32
  • 3-hydroxi-anthranilic acid is early expressed in stroke

    A. Mangas, J. Yajeya, N. González, I. Ruiz, M. Geffard, R. Coveñas
    02-12-2016
    https://doi.org/10.4081/ejh.2016.2709
    2376
    PDF: 739
    HTML: 312
  • Double-labelling of astrocytes containing GFAP and KYNA or GFAP and 3-HAA

    Overexpression of kynurenic acid and 3-hydroxyanthranilic acid after rat traumatic brain injury

    Arturo Mangas, Margarita Heredia, Adelaida Riolobos, Antonio de la Fuente, José María Criado, Javier Yajeya, Michel Geffard, Rafael Coveñas
    14-11-2018
    https://doi.org/10.4081/ejh.2018.2985
    2282
    PDF: 845
    HTML: 28
  • Gemst: a taylor-made combination that reverts neuroanatomical changes in stroke

    Arturo Mangas, Javier Yajeya, Noelia González, Isabel Ruiz, Marianny Pernía, Michel Geffard, Rafael Coveñas
    25-05-2017
    https://doi.org/10.4081/ejh.2017.2790
    1905
    PDF: 737
    HTML: 199
  • Microglia of teleosts: facing a challenge in neurobiology

    B Cuoghi, L Mola
    231-240
    10-08-2009
    https://doi.org/10.4081/1147
    628
    PDF: 1247
  • Glyphosate, AMPA and glyphosate-based herbicide exposure leads to GFAP, PCNA and caspase-3 increased immunoreactive area on male offspring rat hypothalamus

    Ewing Duque-Díaz, Hernán Hurtado Giraldo, Linda P. Rocha-Muñoz, Rafael Coveñas
    13-10-2022
    https://doi.org/10.4081/ejh.2022.3428
    2111
    HTML: 71
    PDF: 845
  • miR-132 regulates the expression of synaptic proteins in APP/PS1 transgenic mice through C1q

    Nan Xu, Ang-Di Li, Li-Li Ji, Yao Ye, Zhen-Yu Wang, Lei Tong
    03-05-2019
    https://doi.org/10.4081/ejh.2019.3008
    2961
    PDF: 1233
    HTML: 21
  • Immunohistochemical markers of neural progenitor cells in the early embryonic human cerebral cortex

    L. Vinci, A. Ravarino, V. Fanos, A.G. Naccarato, G. Senes, C. Gerosa, G. Bevilacqua, G. Faa, R. Ambu
    01-02-2016
    https://doi.org/10.4081/ejh.2016.2563
    4666
    PDF: 2497
    HTML: 1618
  • ECRG4 expression in normal rat tissues: expression study and literature review

    A. Porzionato, M. Rucinski, V. Macchi, G. Sarasin, L.K. Malendowicz, R. De Caro
    18-05-2015
    https://doi.org/10.4081/ejh.2015.2458
    3102
    PDF: 1205
    Supplementary: 401
    HTML: 1020
  • NEUROBIOLOGY OF SUICIDE: MORPHOLOGICAL ASSESSMENT OF MICROGLIAL NETWORK IN HUMAN POST-MORTEM PREFRONTAL CORTEX Tambuzzi S1, Bertolotto N2, Massari S2, Madaschi L3, Alini M2, Brandolese D2, Ubezio MC1, Cattaneo C1 and Amadeo A2 | 1Institute of Forensic Medicine, Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy; 2Department of Biosciences, Università degli Studi di Milano, Milan, Italy; 3UNITECH NOLIMITS, Università degli Studi di Milano, Milan, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4459
    318
  • Immunohistochemical demonstration of specific antigens in the human brain fixed in zinc-ethanol-formaldehyde

    D.E. Korzhevskii, E.G. Sukhorukova, O.V. Kirik, I.P. Grigorev
    05-08-2015
    https://doi.org/10.4081/ejh.2015.2530
    2839
    PDF: 940
    HTML: 1389
  • Galunisertib enhances chimeric antigen receptor-modified T cell function

    Zhixiong Wang, Qian Liu, Na Risu, Jiayu Fu, Yan Zou, Jiaxing Tang, Long Li, Hui Liu, Guomin Zhou, Xuekai Zhu
    19-06-2020
    https://doi.org/10.4081/ejh.2020.3122
    2113
    PDF: 1122
    Supplementary: 181
    HTML: 20
  • P13 | MORPHO-FUNCTIONAL DIFFERENCES IN THE GUT OF AGED MICE WITH THE POSSIBLE EFFECTS OF ANTI-INFLAMMATORY TREATMENTS A. Casini1, S. Leone1, R. Mancinelli1, R. Vaccaro1, M. Catalano2, G. D’Alessandro2, A. Rinaldi2, A. Reccagni2, G. Vivacqua3, A. Franchitto4, P. Onori1, C. Limatola2, E. Gaudio1 | 1Department of Anatomical, Histological, Forensic Medicine and Orthopaedics Sciences, Sapienza University of Rome, Italy; 2Department of Physiology and Pharmacology, Sapienza University of Rome, Italy; 3Department of Medicine and Surgery, University Campus BioMedico of Rome, Italy; 4Department of Movement, Human and Health Sciences, Division of Health Sciences, University of Rome «Foro Italico», Rome,Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4333
    175
  • P30 | P75NTR MODULATION IMPROVES RESILIENCE TO OXIDATIVE DAMAGE IN A MICROGLIAL CELL MODEL OF PARKINSON’S DISEASE A. Valenza1, D. Pensabene2, F. Rendina1, M. Muzzi2, A. Fracassi3, M. Segatto2, S. Moreno1|3 | 1Dept. of Science, University Roma Tre, Rome, Italy; 2Dept. of Biosciences and Territory, University of Molise, Pesche, Italy; 3Dept. of Neurology, UTMB, Galveston, TX, USA

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4726
    94
    PDF: 16
  • Antigen retrieval pre-treatment causes a different expression pattern of Cav3.2 in rat and mouse spinal dorsal horn

    Xiao E Cheng, Long Xian Ma, Xiao Jin Feng, Meng Ye Zhu, Da Ying Zhang, Lin Lin Xu, Tao Liu
    23-01-2019
    https://doi.org/10.4081/ejh.2019.2988
    2121
    PDF: 898
    Supplementary: 241
    HTML: 39
  • Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model

    Juan Fan, Yu Ma, Liying Sun, Suhua Miao, Jianghong He
    20-04-2026
    https://doi.org/10.4081/ejh.2026.4533
    502
    PDF: 279
    HTML: 15
  • miR-19a targeting CLCA4 to regulate the proliferation, migration, and invasion of colorectal cancer cells

    Huiwen Li, Bo Huang
    10-03-2022
    https://doi.org/10.4081/ejh.2022.3381
    2158
    PDF: 744
    HTML: 29
  • Co-transplantation of bone marrow mesenchymal stem cells and monocytes in the brain stem to repair the facial nerve axotomy

    Li Wu, Dan Han, Jie Jiang, Xiaojie Xie, Xunran Zhao, Tengfei Ke, Wen Zhao, Liu Liu, Wei Zhao
    19-06-2020
    https://doi.org/10.4081/ejh.2020.3136
    1712
    PDF: 832
    HTML: 19
  • GLIAL INFLAMMASOME ACTIVATION AND BLOOD-BRAIN BARRIER BREAKDOWN IN AGE-RELATED NEURODEGENERATION Errede M1, Girolamo F1, d’Amati A1,2, de Giorgis M1, Lorusso L1, Pierucci C3, Bernardini N3, Pellegrini C3, Virgintino D1 and Annese T2 | 1University of Bari, Department of Translational Biomedicine and Neuroscience – Human Anatomy and Histology Unit, Bari, Italy; 2Libera Università del Mediterraneo (LUM) Giuseppe Degennaro University, Department of Medicine and Surgery, Bari, Italy; 3University of Pisa, Department of Clinical and Experimental Medicine - Unit of Histology and Medical Embryology, Pisa, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4460
    517
  • Bradykinin and noradrenaline preconditioning influences level of antioxidant enzymes SOD, CuZn-SOD, Mn-SOD and catalase in the white matter of spinal cord in rabbits after ischemia/reperfusion

    Marianna Danková, Iveta Domoráková, Zuzana Fagová, Milan Stebnický, Alexandra Kunová, Eva Mechírová
    18-10-2019
    https://doi.org/10.4081/ejh.2019.3045
    1688
    PDF: 742
    HTML: 13
  • Effects of piperlonguminine on lung injury in severe acute pancreatitis via the TLR4/NF-κB pathway

    Qian Hu, Ran Tao, Xiaoyun Hu, Haibo Wu, Jianjun Xu
    20-03-2023
    https://doi.org/10.4081/ejh.2023.3639
    1305
    PDF: 765
    HTML: 26
  • P01 | BET PROTEIN INHIBITION ATTENUATES MICROGLIAL ACTIVATION AND OXIDATIVE STRESS IN A CELLULAR MODEL OF PARKINSON’S DISEASE E. Bisesto1, D. Pensabene1, M. Colardo1, M. Varone1, M. Segatto1 | 1Dept. of Biosciences and territory, University of Molise, Pesche (IS), Italy

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4697
    81
    PDF: 19
  • Effects of cadmium on the glial architecture in lizard brain

    Rossana Favorito, Antonio Monaco, Maria C. Grimaldi, Ida Ferrandino
    23-01-2017
    https://doi.org/10.4081/ejh.2017.2734
    3119
    PDF: 828
    HTML: 371
  • P06 | MODELING THE COMPLEXITY OF THE CENTRAL NERVOUS SYSTEM WITH PATIENT IPSC-DERIVED CEREBRAL ORGANOIDS L. Carpinelli1, D. Sibilia1, P.N. Doronzio2, F. Giacalone1, C. Lisciandrello2, E. Guadagni2, A. Conte3, S. Lattante4, M. Magatti5, A. Silini5, Facility Biobanca6, Facility Citometria a Flusso6, L. Di Pietro1|2, M. Sabatelli3, O. Parolini1|2 | 1Fondazione Policlinico Universitario A. Gemelli IRCSS, Rome, Italy; 2Dipartimento di Scienze della Vita e Sanità Pubblica, Università Cattolica del Sacro Cuore, Rome, Italy; 3Centro Clinico NEMO, Fondazione Policlinico Gemelli IRCCS, Rome, Italy; 4Department of Experimental Medicine, University of Salento, Lecce, Italy; 5Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy; 6Gemelli Science and Technology Park (GSTeP), Fondazione Policlinico Universitario A. Gemelli IRCSS, Rome, Italy

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4702
    47
    PDF: 20
  • Sufentanil alleviates cerebral ischemia-reperfusion injury by inhibiting inflammation and protecting the blood-brain barrier in rats

    Zhen Wang, Xiaoyan Du, Daoyang Yu, Yang Yang, Gaoen Ma, Xueli Jia, Lulu Cheng
    12-01-2022
    https://doi.org/10.4081/ejh.2022.3328
    2323
    PDF: 1325
    HTML: 100
  • Immunoreactivity for thymosin beta 4 and thymosin beta 10 in the adult rat oro-gastro-intestinal tract

    S. Nemolato, J. Ekstrom, T. Cabras, C. Gerosa, D. Fanni, E. Di Felice, A. Locci, I. Messana, M. Castagnola, G. Faa
    e17
    07-05-2013
    https://doi.org/10.4081/ejh.2013.e17
    2533
    PDF: 806
    HTML: 532
  • Visnagin ameliorates myocardial ischemia/reperfusion injury through the promotion of autophagy and the inhibition of apoptosis

    Hai-rong Fu, Xiao-shan Li, Yong-hui Zhang, Bin-bin Feng, Lian-hong Pan
    07-09-2020
    https://doi.org/10.4081/ejh.2020.3131
    1340
    PDF: 965
    HTML: 16
  • Expression of S100β during mouse cochlear development

    Wenjing Liu, Yongchun Zhang, Cheng Liang, Lizhong Su
    10-03-2025
    https://doi.org/10.4081/ejh.2025.4189
    1488
    PDF: 416
    Supplementary: 82
    HTML: 9
  • Cannabinoid CB2 receptors are involved in the protection of RAW264.7 macrophages against the oxidative stress: an in vitro study

    Sabrina Giacoppo, Agnese Gugliandolo, Oriana Trubiani, Federica Pollastro, Gianpaolo Grassi, Placido Bramanti, Emanuela Mazzon
    23-01-2017
    https://doi.org/10.4081/ejh.2017.2749
    6122
    PDF: 1391
    HTML: 404
  • Histochemical approaches to assess cell-to-cell transmission of misfolded proteins in neurodegenerative diseases

    G. Natale, E. Pompili, F. Biagioni, S. Paparelli, P. Lenzi, F. Fornai
    e5
    07-03-2013
    https://doi.org/10.4081/ejh.2013.e5
    3375
    PDF: 817
    HTML: 209
  • Characterization of kynurenine pathway in patients with diarrhea-predominant irritable bowel syndrome

    Pingping Li, Jimin Zheng, Yun Bai, Dingxin Wang, Zijin Cui, Yueqin Li, Jian Zhang, Yuzhen Wang
    19-06-2020
    https://doi.org/10.4081/ejh.2020.3132
    2286
    PDF: 1192
    HTML: 22
  • Degenerative effects in rat eyes after experimental ocular hypertension

    G. Scarsella, M. Nebbioso, S. Stefanini, N. Pescosolido
    e42
    08-10-2012
    https://doi.org/10.4081/ejh.2012.e42
    1581
    PDF: 620
    HTML: 204
  • Management of autofluorescence in formaldehyde-fixed myocardium: choosing the right treatment

    Zhao Zhang, Hongming Fan, William Richardson, Bruce Z. Gao, Tong Ye
    02-10-2023
    https://doi.org/10.4081/ejh.2023.3812
    2068
    PDF: 1118
    Supplementary: 130
    HTML: 35
  • Gliocyte and synapse analyses in cerebral ganglia of the Chinese mitten crab, Eriocheir sinensis: ultrastructural study

    H. Zhang, P. Yu, S. Zhong, T. Ge, S. Peng, Z. Zhou, X. Guo
    10-08-2016
    https://doi.org/10.4081/ejh.2016.2655
    1743
    PDF: 786
    HTML: 424
  • miR-1270 enhances the proliferation, migration, and invasion of osteosarcoma via targeting cingulin

    Yang Liu, Weichun Guo, Shuo Fang, Bin He, Xiaohai Li, Li Fan
    07-12-2021
    https://doi.org/10.4081/ejh.2021.3237
    1763
    PDF: 601
    HTML: 28
  • Thrombin regulates the ability of Schwann cells to support neuritogenesis and to maintain the integrity of the nodes of Ranvier

    Elena Pompili, Viviana Ciraci, Stefano Leone, Valerio De Franchis, Pietro Familiari, Roberto Matassa, Giuseppe Familiari, Ada Maria Tata, Lorenzo Fumagalli, Cinzia Fabrizi
    30-03-2020
    https://doi.org/10.4081/ejh.2020.3109
    2131
    PDF: 954
    HTML: 40
  • Neurodegeneration in zebrafish embryos and adults after cadmium exposure

    Antonio Monaco, Teresa Capriello, Maria C. Grimaldi, Valentina Schiano, Ida Ferrandino
    19-10-2017
    https://doi.org/10.4081/ejh.2017.2833
    3369
    PDF: 1338
    HTML: 156
  • The possible alleviating effect of garlic supplement on the neural retina in a rat model of hypercholesterolemia: a histological and immunohistochemical study

    Eetmad A. Arafat, Eman M.I. Youssef, Hanaa A. Khalaf
    16-12-2021
    https://doi.org/10.4081/ejh.2021.3322
    1338
    PDF: 587
    HTML: 25
  • Immunohistochemical detection of acth and msh cells in the hypophysis of the hermaphroditic teleost, Diplodus sargus

    I Ferrandino, A Pica, M Consiglio Grimaldi
    397-406
    23-12-2009
    https://doi.org/10.4081/ejh.2000.1604
    116
    PDF: 40
  • Imaging techniques in nanomedical research

    Laura Calderan, Manuela Malatesta
    01-07-2020
    https://doi.org/10.4081/ejh.2020.3151
    2099
    PDF: 840
    HTML: 25
  • Immunohistochemical analysis of YB-1 expression in the developing mouse eye

    Alexander Forian Nass, Hella Wolf, Saadettin Sel , Thomas Kalinski, Norbert Nass
    03-11-2025
    https://doi.org/10.4081/ejh.2025.4244
    1643
    PDF: 272
    HTML: 31
  • Long noncoding RNA Meg3 mediates ferroptosis induced by oxygen and glucose deprivation combined with hyperglycemia in rat brain microvascular endothelial cells, through modulating the p53/GPX4 axis

    Cheng Chen, Yan Huang, Pingping Xia, Fan Zhang, Longyan Li, E Wang, Qulian Guo, Zhi Ye
    30-09-2021
    https://doi.org/10.4081/ejh.2021.3224
    3734
    PDF: 1928
    HTML: 42
  • Histological structure of Rana dybowskii oviducts in the breeding period

    Expressions of TLR4, MyD88, IRAK4 and NF-κΒ in the oviduct of Chinese brown frog (Rana dybowskii)

    Yue Zhang, Ao Zhang, Yue Zhao, Xiaohang Feng, Yuyao Sheng, Haolin Zhang, Qiang Weng, Meiyu Xu
    25-09-2019
    https://doi.org/10.4081/ejh.2019.3050
    1134
    PDF: 581
    HTML: 19
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
Nana Bao et al.
20 April 2026
Vol. 70 No. 2 (2026)
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells
Huina Su et al.
21 April 2026
Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

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