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27 | CELLULAR AND MOLECULAR MECHANISMS OF GADOLINIUM TOXICITY IN SERTOLI CELLS Sara Falvo1, Giulia Grillo1, Gabriella Chieffi Baccari1, Giuseppe Petito1, Massimo Venditti2, Maria Maddalena Di Fiore1, Tiziana Cappello3, Maria Maisano3, Alessandra Santillo1 | 1Dept of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania L. Vanvitelli, Caserta, Italy; 2Dept of Experimental Medicine, University of Campania L. Vanvitelli, Napoli, Italy; 3Dept of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy
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P22 | COORDINATION OF MITOPHAGY AND EMT PROGRAMS IN BRAIN TUMOR CELL PLASTICITY Ilaria Montano1, Valeria Nanni1, Manuela Giansanti2, Veronica Marabitti1|3, Francesca Nazio1 | 1Department of Biology, University of Rome Tor Vergata, Rome, Italy; 2Innate Lymphoid Cells Unit, Bambino Gesù Children's Hospital IRCCS, Rome, Italy; 3Dipartimento di Scienze Biotecnologiche di Base, Cliniche Intensivologiche e Perioperatorie, Università Cattolica del Sacro Cuore, Rome, Italy
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53 | CYTOTOXIC EFFECTS OF NANOPLASTICS ON THE MALE GONADS OF MYTILUS GALLOPROVINCIALIS Migliaccio Vincenzo1, Romano Rossana2, Luigi Rosati3, Lionetti Lillà1, Motta Chiara Maria3, Palma Simoniello2 | 1Dept. Chemistry and Biology “Adolfo Zambelli” University of Salerno, Italy; 2Dept. of Science and Technology, University Parthenope, Napoli, Italy; 3Dept. of Biology, University of Naples Federico II, Napoli, Italy
219PDF: 138 -
ROLE OF MITOCHONDRIAL METABOLISM AND CONTACT SITES IN CANCER CELL DEATH AND SURVIVAL F. Severin, A. Ruzza, F. Vianello, E. Zaltron, I. Celotti, M. Scavezzon, S. Toffanin, C. Bastianello, L. Leanza | Department of Biology, University of Padova, Padova, Italy
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TRACKING HER2 TRAFFICKING AND ORGANELLE CROSSTALK IN TRASTUZUMAB-DERUXTECAN–TREATED BREAST CANCER CELLS USING MULTIMODAL IMAGING E. Tagliatti1, M. C. Gagliani2, G. Bellese2, M. Crippa3, A. Abbona4, M. Paccagnella4, P. Arnaldi5, M. C. Merlano6, O. Garrone7, A.M. Porcelli8, M. Matteoli1, P. Falletta9, P. Castagnola10, K. Cortese2 | 1IRCCS Humanitas Research Hospital, Laboratory of Pharmacology and Brain Pathology, Rozzano, Milano, Italy; 2DIMES, Department of Experimental Medicine, Cellular Electron Microscopy Lab, University of Genoa, Genoa, Italy; 3Experimental Imaging Center, IRCCS Ospedale San Raffaele, Milan, Italy; 4Health Department S. Croce e Carle Teaching Hospital, Cuneo, Italy; 5IRCCS Ospedale Policlinico San Martino, Genova, Italy; 6Scientific Direction, Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy; 7Medical Oncology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy; 8FABIT, Department of Pharmacy and Biotechnology and CIRI, Interdepartmental Centre for Industrial Research ‘Scienze Della Vita e Tecnologie per La Salute’, University of Bologna, Bologna, Italy; 9Vita-Salute San Raffaele University, Milan, Italy; 10IRCCS Ospedale Policlinico San Martino, Genova, Italy
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P55 | ENDOTHELIAL THYMIDINE PHOSPHORYLASE DEFICIENCY TRIGGERS MORPHO-FUNCTIONAL DEGE-NERATION OF ENTERIC NEURONS AND REDUCES INTESTINAL STEM CELL PROLIFERATION I. Neri1, E. Boschetti1, T. Saha2, S. Rommel2, S. Schulte2, M. Gries2, R. De Giorgio3, L. Manzoli1, S. Ratti1, K. Schäfer2 | 1Cellular Signalling Laboratory, Anatomy Center, Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy; 2Workgroup Enteric Nervous System (AGENS), Department of Informatics and Microsystems Technology, University of Applied, Sciences Kaiserslautern, Zweibrücken, Germany; 3Department of Translational Medicine, University of Ferrara, Ferrara, Italy
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