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Colchicine alleviates severe acute pancreatitis in rats by inhibiting acinar cell ferroptosis via LCN2/MAPK/ERK signaling axis
516PDF: 950Supplementary: 55HTML: 22 -
3-hydroxi-anthranilic acid is early expressed in stroke
2431PDF: 763HTML: 319 -
Essential Current Concepts in Stem Cell Biology
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STRESS GRANULES AND α-SYNUCLEIN: INTERPLAY BETWEEN CELLULAR STRESS AND PROTEIN AGGREGATION IN PARKINSON’S DISEASE Zanchi G1, Novello C1, Calogero AM2, Mazzetti S2, Bonaldo B1, Gomez MCL1, Rolando C1, Calandrella D2,3, Pezzoli G2 and Cappelletti G1 | 1Department of Biosciences, University of Milan, Milan, Italy 2Fondazione Pezzoli per la Malattia di Parkinson, Milan, Italy 3Parkinson Institute, ASST G. Pini-CTO, Milan, Milan, Italy
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PARP-1 protein expression in glioblastoma multiforme
3543PDF: 1401HTML: 1884 -
P01 | BET PROTEIN INHIBITION ATTENUATES MICROGLIAL ACTIVATION AND OXIDATIVE STRESS IN A CELLULAR MODEL OF PARKINSON’S DISEASE E. Bisesto1, D. Pensabene1, M. Colardo1, M. Varone1, M. Segatto1 | 1Dept. of Biosciences and territory, University of Molise, Pesche (IS), Italy
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MicroRNA-29b-3p promotes 5-fluorouracil resistance via suppressing TRAF5-mediated necroptosis in human colorectal cancer
2198PDF: 1102Supplementary: 221HTML: 24 -
P30 | P75NTR MODULATION IMPROVES RESILIENCE TO OXIDATIVE DAMAGE IN A MICROGLIAL CELL MODEL OF PARKINSON’S DISEASE A. Valenza1, D. Pensabene2, F. Rendina1, M. Muzzi2, A. Fracassi3, M. Segatto2, S. Moreno1|3 | 1Dept. of Science, University Roma Tre, Rome, Italy; 2Dept. of Biosciences and Territory, University of Molise, Pesche, Italy; 3Dept. of Neurology, UTMB, Galveston, TX, USA
138PDF: 45 -
VGF AS BIOMARKER OF PRE-SYMPTOMATIC PHASE OF PARKINSON’S DISEASE Manai AL1, Modi A2, Noli B1, Choudhary SM2, Ruda-Kucerova J3, Dražanová E3,4, Khairnar A2,5, Cocco C1 | 1Department of Biomedical Sciences, University of Cagliari, Monserrato, Italy; 2International Clinical Research Center, St. Anne’s University Hospital Brno, Czech Republic; 3Department of Pharmacology, Faculty of Medicine, Masaryk University, Brno, Czech Republic; 4Institute of Scientific Instruments of the CAS, v. v. i., Brno, Czech Republic; 5Department of Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic
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CONNECTOME-BASED BRAIN FINGERPRINTS PREDICT ART THERAPY RESPONSE IN PARKINSON’S DISEASE Ielo A1,§, Genovese D2,3,§, Falcó-Roget J4, Amico E5,6, Norcini M7, Quartarone A1, Ghilardi MF8 and Cacciola A9,10 | 1IRCCS Centro Neurolesi Bonino Pulejo, Messina, Italy; 2Institute of Neurology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; 3Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy; 4Computational Neuroscience Group, Sano Centre for Computational Medicine, Kraków, Poland; 5School of Mathematics, University of Birmingham, Birmingham, UK; 6Centre for Human Brain Health, University of Birmingham, Birmingham, UK; 7NYU Langone Health, Department of Neurology, New York, USA; 8Department of Molecular, Cellular & Biomedical Sciences, School of Medicine, City University of New York, New York, USA; 9Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy; 10IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy. §Shared co-first authorship
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P23 | CALRETININ IMMUNOREACTIVE NON-TRADITIONAL LARGE NEURONS IN THE GRANULAR LAYER OF THE HUMAN CEREBELLAR CORTEX P. Flace1, M. E. Caringella2, D. Galletta3, G. Santangelo3, C. Caporusso2, M. Stolfa2, A. Cacciola4, J.J.V. Branca5, G. Agazzino2, R. Gradini6, P. Livrea7, A. Marzullo2 | 1Medical School, University of Bari ‘Aldo Moro’, Bari, Italy; 2Section of Molecular Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari ‘Aldo Moro’, Italy; 3Department of Psychology, Specialization School of Neuropsychology. University of Campania ‘Luigi Vanvitelli’, Caserta, Italy; 4Brain Mapping Lab, Department of Biomedical, Dental Sciences and Morphological and Functional Imaging, University of Messina, Messina, Italy; 5Department of Experimental and Clinical Medicine, University of Firenze, Firenze, Italy; 6Department of Experimental Medicine, Sapienza University, Roma, Italy; 7University of Bari ‘Aldo Moro’, Bari, Italy
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22 | TRANSCRIPTIONAL AND POST-TRANSLATIONAL NETWORKS COORDINATE SELECTIVE AUTOPHAGY TO MAINTAIN ORGANELLE HOMEOSTASIS K. Hartfelt1, M. Petraroia2, T. Persichini2, M. Colasanti2, C. Di Malta3, F. Cecconi4, V. Cianfanelli2 | 1Unit of Cell Stress and Survival, Danish Cancer Institute, Copenhagen, Denmark; 2Dept. of Science, University Roma TRE, Rome, Italy; 3Telethon Institute of Genetics and Medicine, Naples, Italy; 4Dept. of Basic Biotechnological Sciences, Intensive Care and Perioperative Clinics Research, Catholic University of the Sacred Heart, Rome, Italy
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61 | ROTENONE-INDUCED OXIDATIVE STRESS TRIGGERS PEROXISOMAL ALTERATIONS IN BV-2 MICROGLIAL CELLS F. Rendina1, A. Valenza1, M. Muzzi2, D. Pensabene2, A. Fracassi3, M. Segatto2, S. Moreno1|3 | 1Dept. of Science, University Roma Tre, Rome, Italy. 2Dept. of Biosciences and Territory, University of Molise, Pesche, Italy. 3Dept. of Neurology, UTMB, Galveston, TX, USA
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ALPHA SYNUCLEIN REGULATION IN BRAIN AND BONE MARROW IS RELETED TO THE DIFFERENTIAL EXPRESSION OF GATA1 TRANSCRIPTION FACTOR Velardi V1, Arciprete F1, Caturano C1, Rana RA1, Mancinelli R2, Zingariello M1 and Vivacqua G1 | 1Unit of Microscopic and Ultrastructural Anatomy, University Campus Bio-Medico, Rome, Italy; 2Department of Anatomic, Histologic, Forensic Medicine and Locomotor Apparatus Science, Sapienza University of Rome, Italy
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Stem Cells and Therapy: Emerging Approaches
2179PDF: 421HTML: 12 -
CALRETININ IMMUNOREACTIVITY IN NERVE CELLS OF THE HUMAN MIDBRAIN AND THEIR POTENTIAL ROLE IN NEURODEGENERATIVE DISORDERS Flace P1, Caporusso C2, Galletta D3, Stolfa M2, Cacciola A4,5, Scarcella VS2, Branca JJV6, Gulisano M6, Milardi D7, Gradini R8, Livrea P9 and Marzullo A2 | 1Medical School, University of Bari Aldo Moro, Bari, Italy; 2Department of Precision and Regenerative Medicine and Ionian Area, Pathology Unit, University of Bari Aldo Moro, Bari, Italy; 3Specialization School Neuropsychology, University of Campania Luigi Vanvitelli, Caserta, Italy; 4IRCCS Humanitas Research Hospital, Milan, Italy; 5Department of Biomedical Sciences, Humanotas University, Milan, Italy; 6Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; 7Brain Mapping Lab, Department of Biomedical, Dental Sciences and Morphological and Functional Imaging, University of Messina, Messina, Italy; 8Department of Experimental Medicine, Sapienza University, Roma, Italy; 9University of Bari Aldo Moro, Bari, Italy
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GAIT CHARACTERIZATION IN A MOUSE MODEL OF CHRONIC MILD STRESS- AND 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE-INDUCED NEUROINFLAMMATION Serinelli FC1, Kashyrina M2, De Nuccio F2, Panaro MA3, Cianciulli A3, Ruggiero M3, Porro C4, Ichas F5, Nicolardi N1 and Lofrumento DD1 | 1Department of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, Lecce, Italy; 2Department of Experimental Medicine, University of Salento, Lecce, Italy; 3Department of Biosciences, Biotechnologies and Environment, University of Bari, Italy; 4Department of Clinical and Experimental Medicine, University of Foggia, Italy; 5Institut des Maladies Neurodégénératives, CNRS, Université de Bordeaux, France
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