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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

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1.9
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3.7
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  • Fibroblast activating protein-α expression in squamous cell carcinoma of the esophagus in primary and irradiated tumors: the use of archival FFPE material for molecular techniques

    Renata Tabola, Magdalena Zaremba-Czogalla, Dagmara Baczynska, Roberto Cirocchi, Kamila Stach, Krzysztof Grabowski, Katarzyna Augoff
    20-06-2017
    https://doi.org/10.4081/ejh.2017.2793
    1825
    PDF: 764
    HTML: 100
  • Walking a thin line between fixation and epitope binding – characterization of antigen retrieval methods suitable for eosinophil and HSV-2 staining in formalin-fixed female reproductive tissue

    Lisa Marie Wadephul, Kathrin Arndts, Gnatoulma Katawa, Eva Dietlmeier, William Horsnell, Achim Hoerauf, Manuel Ritter
    16-04-2024
    https://doi.org/10.4081/ejh.2024.3929
    1612
    PDF: 552
    HTML: 19
  • From fix to fit into the autoptic human brains

    Beatrice Paradiso, Michele Simonato, Gaetano Thiene, Anna Lavezzi
    27-08-2018
    https://doi.org/10.4081/ejh.2018.2944
    2075
    PDF: 1365
    HTML: 54
  • GPX4 and GPX7 over-expression in human hepatocellular carcinoma tissues

    E. Guerriero, F. Capone, M. Accardo, A. Sorice, M. Costantini, G. Colonna, G. Castello, S. Costantini
    01-12-2015
    https://doi.org/10.4081/ejh.2015.2540
    3884
    PDF: 1211
    Supplementary: 462
    HTML: 661
  • Overexpression of ubiquitin-specific protease 22 predicts poor survival in patients with early-stage non-small cell lung cancer

    J. Ning, J. Zhang, W. Liu, Y. Lang, Y. Xue, S. Xu
    e46
    30-11-2012
    https://doi.org/10.4081/ejh.2012.e46
    2546
    PDF: 757
    HTML: 512
  • The penetration of methanol into bovine cardiac and hepatic tissues is faster than ethanol and formalin

    Michelle Steicke, Guang Yang, Tam Nguyen Dinh, Matthew Dunster-Jones, Owen Sargisson, Farah Ahmady, Jonathan Golledge, Yutang Wang
    07-02-2018
    https://doi.org/10.4081/ejh.2018.2880
    2028
    PDF: 836
    Supplementary: 207
    HTML: 53
  • Reliable LC3 and p62 autophagy marker detection in formalin fixed paraffin embedded human tissue by immunohistochemistry

    A.M. Schläfli, S. Berezowska, O. Adams, R. Langer, M.P. Tschan
    05-05-2015
    https://doi.org/10.4081/ejh.2015.2481
    8453
    PDF: 3284
    HTML: 2159
  • DPY30 promotes the growth and survival of osteosarcoma cell by regulating the PI3K/AKT signal pathway

    Gong Cheng, Fengmin An, Zhilin Cao, Mingdi Zheng, Zhongyuan Zhao, Hao Wu
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3413
    1276
    PDF: 648
    Supplementary: 109
    HTML: 35
  • A single simple procedure for dewaxing, hydration and heat-induced epitope retrieval (HIER) for immunohistochemistry in formalin fixed paraffin-embedded tissue

    I.M.S. Paulsen, H. Dimke, S. Frische
    03-11-2015
    https://doi.org/10.4081/ejh.2015.2532
    3480
    PDF: 1748
    HTML: 809
  • Elemental analysis of histological specimens: a method to unmask nano asbestos fibers

    M. Scimeca, A. Pietroiusti, F. Milano, L. Anemona, A. Orlandi, L.T. Marsella, E. Bonanno
    01-02-2016
    https://doi.org/10.4081/ejh.2016.2573
    2477
    PDF: 1618
    HTML: 407
  • Porcine intestinal mast cells. Evaluation of different fixatives for histochemical staining techniques considering tissue shrinkage

    J. Rieger, S. Twardziok, H. Huenigen, R. M. Hirschberg, J. Plendl
    e21
    30-07-2013
    https://doi.org/10.4081/ejh.2013.e21
    4265
    PDF: 1158
    HTML: 1301
  • Identification of 5-hydroxytryptamine-producing cells by detection of fluorescence in paraffin-embedded tissue sections

    Y. Kaneko, N. Onda, Y. Watanabe, M. Shibutani
    29-09-2016
    https://doi.org/10.4081/ejh.2016.2684
    2235
    PDF: 835
    HTML: 311
  • KiSS1 inhibits growth and invasion of osteosarcoma cells through inhibition of the MAPK pathway

    Y. Zhang, Y.J. Tang, Z.H. Li, F. Pan, K. Huang, G.H. Xu
    e30
    29-10-2013
    https://doi.org/10.4081/ejh.2013.e30
    2823
    PDF: 680
    HTML: 315
  • Enhancement of immunohistochemical detection of Salmonella in tissues of experimentally infected pigs

    J. Rieger, P. Janczyk, H. Hünigen, J. Plendl
    09-07-2015
    https://doi.org/10.4081/ejh.2015.2516
    2541
    PDF: 964
    HTML: 1034
  • WT1 expression in the human fetus during development

    R. Ambu, L. Vinci, C. Gerosa, D. Fanni, E. Obinu, A. Faa, V. Fanos
    29-06-2015
    https://doi.org/10.4081/ejh.2015.2499
    2237
    PDF: 852
    HTML: 984
  • Energy Dispersive X-ray (EDX) microanalysis: A powerful tool in biomedical research and diagnosis

    Manuel Scimeca, Simone Bischetti, Harpreet Kaur Lamsira, Rita Bonfiglio, Elena Bonanno
    15-03-2018
    https://doi.org/10.4081/ejh.2018.2841
    15050
    PDF: 7182
    HTML: 484
  • Immunohistochemical study of doublecortin and nucleostemin in canine brain

    E. De Nevi, P. Marco-Salazar, D. Fondevila, E. Blasco, L. Pérez, M. Pumarola
    e9
    20-03-2013
    https://doi.org/10.4081/ejh.2013.e9
    2489
    PDF: 708
    HTML: 283
  • Is there still room for novelty, in histochemical papers?

    Carlo Pellicciari
    16-12-2016
    https://doi.org/10.4081/ejh.2016.2758
    2831
    PDF: 720
    HTML: 281
  • Management of autofluorescence in formaldehyde-fixed myocardium: choosing the right treatment

    Zhao Zhang, Hongming Fan, William Richardson, Bruce Z. Gao, Tong Ye
    02-10-2023
    https://doi.org/10.4081/ejh.2023.3812
    1968
    PDF: 1019
    Supplementary: 127
    HTML: 35
  • MMP-7 is upregulated by COX-2 and promotes proliferation and invasion of lung adenocarcinoma cells

    J. Zhang, J. Luo, J. Ni, L. Tang, H.P. Zhang, L. Zhang, J.F. Xu, D. Zheng
    18-02-2014
    https://doi.org/10.4081/ejh.2014.2262
    3486
    PDF: 1031
    HTML: 329
  • Differential expression patterns of N-acetylglucosaminyl transferases and polylactosamines in uterine lesions

    A.T.R. Clark, V.M.L. Guimaraes da Costa, L. Bandeira Costa, C.L. Bezerra Cavalcanti, M.J.B. de Melo Rego, E.I.C. Beltrao
    26-05-2014
    https://doi.org/10.4081/ejh.2014.2334
    2470
    PDF: 1763
    HTML: 404
  • Metformin sensitises osteosarcoma to chemotherapy via the IGF-1R/miR-610/FEN1 pathway

    Suwei Dong, Yanbin Xiao, Ziqiang Zhu, Xiang Ma, Zhuohui Peng, Jianping Kang, Jianqiang Wang, Yunqing Wang, Zhen Li
    17-05-2023
    https://doi.org/10.4081/ejh.2023.3612
    1400
    PDF: 928
    Supplementary: 100
    HTML: 24
  • miR-26b regulates cell proliferation and apoptosis of CD117+CD44+ ovarian cancer stem cells by targeting PTEN

    Zubiao Gao, Xiaofeng Ye, Anne Bordeaux, Stanka Hettich, Siyao Lin, Fang Han, Yan Jia
    04-02-2021
    https://doi.org/10.4081/ejh.2021.3186
    2289
    PDF: 732
    HTML: 21
  • Expression of SPANX proteins in normal prostatic tissue and in prostate cancer

    M. Salemi, A. E. Calogero, G. Zaccarello, R. Castiglione, A. Cosentino, C. Campagna, E. Vicari, G. Rappazzo
    e41
    09-09-2010
    https://doi.org/10.4081/ejh.2010.e41
    1578
    PDF: 538
    HTML: 1353
  • Successful triple immunoenzymatic method employing primary antibodies from same species and same immunoglobulin subclass

    T. A. Osman, G. Øijordsbakken, D. E. Costea, A. C. Johannessen
    e22
    16-09-2013
    https://doi.org/10.4081/ejh.2013.e22
    3217
    PDF: 866
    HTML: 2121
  • LncRNA GClnc1 may contribute to the progression of ovarian cancer by regulating p53 signaling pathway

    Hu Li, Zheng Zeng, Xiang Yang, Ye Chen, Lei He, Ting Wan
    10-11-2020
    https://doi.org/10.4081/ejh.2020.3166
    1008
    PDF: 657
    HTML: 20
  • PARP-1 protein expression in glioblastoma multiforme

    A. Galia, A.E. Calogero, R. Condorelli, F. Fraggetta, A. La Corte, F. Ridolfo, P. Bosco, R. Castiglione, M. Salemi
    e9
    27-02-2012
    https://doi.org/10.4081/ejh.2012.e9
    3289
    PDF: 1304
    HTML: 1816
  • Routinely frozen biopsies of human skeletal muscle are suitable for morphological and immunocytochemical analyses at transmission electron microscopy

    M. Giagnacovo, R. Cardani, G. Meola, C. Pellicciari, M. Malatesta
    e31
    08-07-2010
    https://doi.org/10.4081/ejh.2010.e31
    1561
    PDF: 785
    HTML: 9363
  • Hepatocyte growth factor intervention to reduce myocardial injury and improve cardiac function on diabetic myocardial infarction rats

    Zaiyong Zhang, Cheng Long, Yufeng Guan, Mingcai Song
    30-07-2020
    https://doi.org/10.4081/ejh.2020.3142
    1385
    PDF: 754
    HTML: 17
  • Bleaching melanin in formalin-fixed and paraffin-embedded melanoma specimens using visible light: a pilot study

    Claudio Pigoli, Lucia Rita Gibelli, Mario Caniatti, Luca Moretti, Giuseppe Sironi, Chiara Giudice
    31-10-2019
    https://doi.org/10.4081/ejh.2019.3071
    1689
    PDF: 974
    HTML: 13
  • Knockdown of RAGE inhibits growth and invasion of gastric cancer cells

    X.C. Xu, X. Abuduhadeer, W.B. Zhang, T. Li, H. Gao, Y.H. Wang
    e36
    18-11-2013
    https://doi.org/10.4081/ejh.2013.e36
    4313
    PDF: 845
    HTML: 268
  • Concomitant use of heat-shock protein 70, glutamine synthetase and glypican-3 is useful in diagnosis of HBV-related hepatocellular carcinoma with higher specificity and sensitivity

    Bita Moudi, Zahra Heidari, Hamidreza Mahmoudzadeh-Sagheb, Seyed-Moayed Alavian, Kamran B. Lankarani, Parisa Farrokh, Jens Randel Nyengaard
    29-01-2018
    https://doi.org/10.4081/ejh.2018.2859
    2252
    PDF: 1081
    HTML: 81
  • Thymosin beta 4 and thymosin beta 10 expression in hepatocellular carcinoma

    W. Theunissen, D. Fanni, S. Nemolato, E. Di Felice, T. Cabras, C. Gerosa, P. Van Eyken, I. Messana, M. Castagnola, G. Faa
    11-03-2014
    https://doi.org/10.4081/ejh.2014.2242
    3226
    PDF: 1040
    HTML: 489
  • Immunohistochemical demonstration of specific antigens in the human brain fixed in zinc-ethanol-formaldehyde

    D.E. Korzhevskii, E.G. Sukhorukova, O.V. Kirik, I.P. Grigorev
    05-08-2015
    https://doi.org/10.4081/ejh.2015.2530
    2790
    PDF: 920
    HTML: 1388
  • Immunopositivity for Siglec-15 in gastric cancer and its association with clinical and pathological parameters

    Michael Williams Leal Quirino, Michelly Cristiny Pereira, Maria de Fátima Deodato de Souza, Ivan da Rocha Pitta, Antônio Felix da Silva Filho, Mario S. de Souza Albuquerque, Amanda Pinheiro de Barros Albuquerque, Mário Rino Martins, Maira Galdino da Rocha Pitta, Moacyr Jesus Barreto de Melo Rêgo
    04-03-2021
    https://doi.org/10.4081/ejh.2021.3174
    7453
    PDF: 1274
    Supplementary: 228
    HTML: 18
  • Characterization of PD-1/PD-L1 immune checkpoint expression in soft tissue sarcomas

    Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Masao Akagi
    02-07-2021
    https://doi.org/10.4081/ejh.2021.3203
    3115
    PDF: 938
    HTML: 36
  • Elevated caspase 3 expression correlates with severe inflammation in Crohn’s disease

    Nafie Sejdiu, Michael Naumann, Michael Vieth
    03-06-2026
    https://doi.org/10.4081/ejh.2026.4570
    140
    PDF: 74
    HTML: 4
  • Vitamin D and vitamin D receptor in patients with ophthalmic pterygium

    Cristina Maxia, Daniela Murtas, Michela Corrias, Ignazio Zucca, Luigi Minerba, Franca Piras, Cristiana Marinelli, Maria Teresa Perra
    30-10-2017
    https://doi.org/10.4081/ejh.2017.2837
    1946
    PDF: 1011
    HTML: 75
  • Back to the future: improving storage of Golgi-stained mouse brain

    Fabrizio De Luca
    05-03-2026
    https://doi.org/10.4081/ejh.2026.4532
    369
    PDF: 242
    HTML: 24
  • Expression of Caveolin-1 in tongue squamous cell carcinoma by quantum dots

    J. Xue, H. Chen, L. Diao, X. Chen, D. Xia
    e20
    14-04-2010
    https://doi.org/10.4081/ejh.2010.e20
    1955
    PDF: 633
    HTML: 1583
  • Sporadic Creutzfeldt-Jakob disease: Real-Time Quaking Induced Conversion (RT-QuIC) assay represents a major diagnostic advance

    Federico Angelo Cazzaniga, Edoardo Bistaffa, Chiara Maria Giulia De Luca, Giuseppe Bufano, Antonio Indaco, Giorgio Giaccone, Fabio Moda
    15-10-2021
    https://doi.org/10.4081/ejh.2021.3298
    2790
    PDF: 1136
    HTML: 37
  • Twenty years of histochemistry in the third millennium, browsing the scientific literature

    Carlo Pellicciari
    29-12-2020
    https://doi.org/10.4081/ejh.2020.3213
    1375
    PDF: 539
    HTML: 15
  • The tyrosine kinase receptor c-met, its cognate ligand HGF and the tyrosine kinase receptor trasducers STAT3, PI3K and RHO in thyroid nodules associated with Hashimoto's thyroiditis: an immunohistochemical characterization

    R. M. Ruggeri, E. Vitarelli, G. Barresi, F. Trimarchi, S. Benvenga, M. Trovato
    e24
    03-06-2010
    https://doi.org/10.4081/ejh.2010.e24
    1458
    PDF: 674
    HTML: 2603
  • Effect of royal jelly on experimental colitis Induced by acetic acid and alteration of mast cell distribution in the colon of rats

    T. Karaca, F. Bayiroglu, M.U. Yoruk, S. Kaya, S. Uslu, B. Comba, L. Mis
    e35
    21-10-2010
    https://doi.org/10.4081/ejh.2010.e35
    3711
    PDF: 867
    HTML: 5317
  • Expression pattern of thymosin beta 4 in the adult human liver

    S. Nemolato, P. Van Eyken, T. Cabras, F. Cau, M.U. Fanari, A. Locci, D. Fanni, C.L.P. Gerosa, I. Messana, M. Castagnola, G. Faa
    e25
    07-09-2011
    https://doi.org/10.4081/ejh.2011.e25
    1572
    PDF: 708
    HTML: 1360
  • Pleural mesothelioma from fluoro-edenite exposure: PACAP and PAC1 receptor. A preliminary report

    Claudia Lombardo, Grazia Maugeri, Agata Grazia D'Amico, Giuseppe Broggi, Rosario Caltabiano, Veronica Filetti, Serena Matera, Velia D'Agata, Carla Loreto
    02-05-2024
    https://doi.org/10.4081/ejh.2024.3994
    1570
    PDF: 492
    HTML: 33
  • CCL18 promotes endometriosis by increasing endometrial cell migration and neuroangiogenesis

    Yangying Peng, Shaojie Ding, Ping Xu, Xueyan Zhang, Jianzhang Wang, Tiantian Li, Liyun Liao, Xinmei Zhang
    06-08-2024
    https://doi.org/10.4081/ejh.2024.4052
    1043
    PDF: 719
    HTML: 45
  • Expression of parafibromin in major renal cell tumors

    C. Cui, P. Lal, S. Master, Y. Ma, T. Baradet, Z. Bing
    e39
    23-10-2012
    https://doi.org/10.4081/ejh.2012.e39
    1486
    PDF: 654
    HTML: 225
  • OTX1 and OTX2 as possible molecular markers of sinonasal carcinomas and olfactory neuroblastomas

    Cristina Pirrone, Anna M. Chiaravalli, Alessandro Marando, Andrea Conti, Alessia Rainero, Andrea Pistochini, Francesco Lo Curto, Francesco Pasquali, Paolo Castelnuovo, Carlo Capella, Giovanni Porta
    09-02-2017
    https://doi.org/10.4081/ejh.2017.2730
    2543
    PDF: 1140
    HTML: 356
  • Clinicopathological assessment of cancer/testis antigens NY‑ESO‑1 and MAGE‑A4 in osteosarcoma

    Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Naohiro Oka, Ryosuke Kakinoki, Masao Akagi
    23-06-2022
    https://doi.org/10.4081/ejh.2022.3377
    1751
    PDF: 898
    HTML: 26
  • Expression of E-cadherin, Ki-67, and p53 in urinary bladder cancer in relation to progression, survival, and recurrence

    Stanislav Ziaran, Stefan Harsanyi, Katarina Bevizova, Zuzana Varchulova Novakova, Branislav Trebaticky, Peter Bujdak, Stefan Galbavy, Lubos Danisovic
    26-03-2020
    https://doi.org/10.4081/ejh.2020.3098
    1536
    PDF: 838
    HTML: 26
  • Reelin expression in human liver of patients with chronic hepatitis C infection

    Simone Carotti, Giuseppe Perrone, Michelina Amato, Umberto Vespasiani Gentilucci, Daniela Righi, Maria Francesconi, Claudio Pellegrini, Francesca Zalfa, Maria Zingariello, Antonio Picardi, Andrea Onetti Muda, Sergio Morini
    17-03-2017
    https://doi.org/10.4081/ejh.2017.2745
    3245
    PDF: 1000
    HTML: 367
  • Are podoplanin and ezrin involved in the invasion process of the ameloblastomas?

    Y.F. Costa, K.C. Tjioe, S. Nonogaki, F.A. Soares, J.R. Pereira Lauris, D. Tostes Oliveira
    24-02-2015
    https://doi.org/10.4081/ejh.2015.2451
    1998
    PDF: 709
    HTML: 717
  • Mena, a new available marker in tumors of salivary glands?

    S. Gurzu, M. Krause, I. Ember, L. Azamfirei, G. Gobel, K. Feher, I. Jung
    e8
    07-02-2012
    https://doi.org/10.4081/ejh.2012.e8
    1393
    PDF: 705
    HTML: 4125
  • An improved and cost-effective methodology for the reduction of autofluorescence in direct immunofluorescence studies on formalin-fixed paraffin-embedded tissues

    MS Viegas, TC Martins, F Seco, A do Carmo
    59-66
    30-06-2009
    https://doi.org/10.4081/1013
    2127
    PDF: 1699
  • Exploring the efficacy of AMACR, ERG, and AR immunostains in prostatic adenocarcinoma and their association with novel grade groups

    Mohamed O. Andarawi, Hassan Otifi, Hesham Hassan, Adil A. Yousif , Saadalnour A. Mustafa, Shawgi A. Elsiddig , Asad Ma Babker, Elryah I. Ali , Omer Osman Elhag
    11-02-2025
    https://doi.org/10.4081/ejh.2025.4172
    1351
    PDF: 393
    HTML: 19
  • Aberrant DKK3 expression in the oral leukoplakia and oral submucous fibrosis: a comparative immunohistochemical study

    T. Al-dhohorah, M. Mashrah, Z. Yao, J. Huang
    16-06-2016
    https://doi.org/10.4081/ejh.2016.2629
    2726
    PDF: 847
    HTML: 347
  • A method for semi-automated image analysis of HLA class I tumour epithelium expression in rectal cancer

    Daniëlle Krijgsman, Ronald L.P. van Vlierberghe, Vaios Evangelou, Alexander L. Vahrmeijer, Cornelis J.H. van de Velde, Cornelis F.M. Sier, Peter J.K. Kuppen
    20-05-2019
    https://doi.org/10.4081/ejh.2019.3028
    1629
    PDF: 771
    Supplementary: 218
    HTML: 20
  • Clinicopathological assessment of PD-1/PD-L1 immune checkpoint expression in desmoid tumors

    Kazuhiko Hashimoto, Shunji Nishimura, Yu Shinyashiki, Tomohiko Ito, Ryosuke Kakinoki, Masao Akagi
    26-04-2023
    https://doi.org/10.4081/ejh.2023.3688
    928
    PDF: 555
    HTML: 23
  • The fuss over lipo“fussâ€cin: not all autofluorescence is the same

    B. Sainz Jr., I. Miranda-Lorenzo, C. Heeschen
    12-03-2015
    https://doi.org/10.4081/ejh.2015.2512
    2429
    PDF: 906
    HTML: 1332
  • Different immunohistochemical levels of Hsp60 and Hsp70 in a subset of brain tumors and putative role of Hsp60 in neuroepithelial tumorigenesis

    F. Rappa, E. Unti, P. Baiamonte, F. Cappello, N. Scibetta
    e20
    28-06-2013
    https://doi.org/10.4081/ejh.2013.e20
    2897
    PDF: 721
    HTML: 352
  • Deleted in Liver Cancer 2 (DLC2) protein expression in hepatocellular carcinoma

    Dominika Wolosz, Agnieszka Walczak, Grzegorz Szparecki, Michal Dwojak, Magdalena Winiarska, Ewa Wolinska, Barbara Gornicka
    18-02-2019
    https://doi.org/10.4081/ejh.2019.2981
    1473
    PDF: 752
    HTML: 30
  • Toll-like receptor 4 expression in the epithelium of inflammatory periapical lesions. An immunohistochemical study

    R. Leonardi, R.E. Perrotta, C. Loreto, G. Musumeci, S. Crimi, J.N. dos Santos, M.C. Rusu, P. Bufo, E. Barbato, G. Pannone
    26-10-2015
    https://doi.org/10.4081/ejh.2015.2547
    1871
    PDF: 1064
    HTML: 358
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European Journal of Histochemistry

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