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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

1.9
Impact Factor 2025
3.7
CiteScore 2025
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1.9
Impact Factor 2025
3.7
CiteScore 2025
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  • Astragaloside IV inhibits nasopharyngeal carcinoma progression by inhibiting SATB2/Wnt/PD-L1 pathway and enhancing the killing activity of T cells

    Yinping Zeng, Jiajun Huang, Tingting Duan, Xiaofeng Wang
    28-05-2026
    https://doi.org/10.4081/ejh.2026.4540
    251
    PDF: 197
    HTML: 6
  • Astragaloside IV augments anti-PD-1 therapy to suppress tumor growth in lung cancer by remodeling the tumor microenvironment

    Tao Wu, Shikui Wu, Hui Gao, Haolei Liu, Jun Feng, Ge Yin
    23-10-2024
    https://doi.org/10.4081/ejh.2024.4098
    2398
    PDF: 500
    HTML: 33
  • Tumor cells-derived exosomal PD-L1 promotes the growth and invasion of lung cancer cells in vitro via mediating macrophages M2 polarization

    Xiangjun Lu, Jian Shen, Siyuan Huang, Dongdong Liu, Haitao Wang
    01-08-2023
    https://doi.org/10.4081/ejh.2023.3784
    2094
    PDF: 895
    HTML: 23
  • MAGE-A3/4 and NY-ESO-1 antigens expression in metastatic esophageal squamous cell carcinoma

    T. Bujas, Z. Marusic, M. Peric Balja, A. Mijic, B. Kruslin, D. Tomas
    e7
    21-03-2011
    https://doi.org/10.4081/ejh.2011.e7
    1932
    PDF: 834
    HTML: 997
  • Immunopositivity for Siglec-15 in gastric cancer and its association with clinical and pathological parameters

    Michael Williams Leal Quirino, Michelly Cristiny Pereira, Maria de Fátima Deodato de Souza, Ivan da Rocha Pitta, Antônio Felix da Silva Filho, Mario S. de Souza Albuquerque, Amanda Pinheiro de Barros Albuquerque, Mário Rino Martins, Maira Galdino da Rocha Pitta, Moacyr Jesus Barreto de Melo Rêgo
    04-03-2021
    https://doi.org/10.4081/ejh.2021.3174
    7684
    PDF: 1280
    Supplementary: 230
    HTML: 18
  • Immunohistochemical expression and clinicopathological assessment of PD-1, PD-L1, NY-ESO-1, and MAGE-A4 expression in highly aggressive soft tissue sarcomas

    Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Ryosuke Kakinoki, Masao Akagi
    22-04-2022
    https://doi.org/10.4081/ejh.2022.3393
    1360
    PDF: 727
    HTML: 26
  • Characterization of PD-1/PD-L1 immune checkpoint expression in soft tissue sarcomas

    Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Masao Akagi
    02-07-2021
    https://doi.org/10.4081/ejh.2021.3203
    3158
    PDF: 946
    HTML: 37
  • PD-L1 expression with QR1 and E1L3N antibodies according to histological ovarian cancer subtype: A series of 232 cases

    Caroline Eymerit-Morin, Anna Ilenko, Thomas Gaillard, Justine Varinot, Eva Compérat, Sofiane Bendifallah, Emile Darai
    10-03-2021
    https://doi.org/10.4081/ejh.2021.3185
    1853
    PDF: 779
    HTML: 27
  • Knockdown of miR-411-3p induces M2 macrophage polarization and promotes colorectal cancer progression by regulation of MMP7

    Tianliang Bai, Ping Li, Yabin Liu, Bindan Cai, Gang Li, Wenbin Wang, Rui Yan, Xiangkui Zheng, Shangkun Du
    05-05-2025
    https://doi.org/10.4081/ejh.2025.4178
    966
    PDF: 410
    Supplementary: 52
    HTML: 51
  • Clinicopathological assessment of cancer/testis antigens NY‑ESO‑1 and MAGE‑A4 in osteosarcoma

    Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Naohiro Oka, Ryosuke Kakinoki, Masao Akagi
    23-06-2022
    https://doi.org/10.4081/ejh.2022.3377
    1806
    PDF: 922
    HTML: 26
  • A method for semi-automated image analysis of HLA class I tumour epithelium expression in rectal cancer

    Daniëlle Krijgsman, Ronald L.P. van Vlierberghe, Vaios Evangelou, Alexander L. Vahrmeijer, Cornelis J.H. van de Velde, Cornelis F.M. Sier, Peter J.K. Kuppen
    20-05-2019
    https://doi.org/10.4081/ejh.2019.3028
    1663
    PDF: 778
    Supplementary: 218
    HTML: 20
  • The substance P and neurokinin-1 receptor system in human thyroid cancer: an immunohistochemical study

    Inmaculada Isorna, Francisco Esteban, Juan Solanellas, Rafael Coveñas, Miguel Muñoz
    28-04-2020
    https://doi.org/10.4081/ejh.2020.3117
    1391
    PDF: 732
    HTML: 11
  • Effect of CDX2 on proliferation, invasion, migration, and apoptosis of duodenal cancer cells

    Jun Pan, Yi Zhao, Yu Zhang, Yuhe Zhou, Fengxuan Zhang, Yitian Chen, Xiaoyuan Chu
    24-04-2025
    https://doi.org/10.4081/ejh.2025.4203
    763
    PDF: 335
    HTML: 53
  • Galunisertib enhances chimeric antigen receptor-modified T cell function

    Zhixiong Wang, Qian Liu, Na Risu, Jiayu Fu, Yan Zou, Jiaxing Tang, Long Li, Hui Liu, Guomin Zhou, Xuekai Zhu
    19-06-2020
    https://doi.org/10.4081/ejh.2020.3122
    2085
    PDF: 1108
    Supplementary: 170
    HTML: 20
  • SUSD2 suppresses lung adenocarcinoma tumorigenesis by inducing autophagy via inhibiting PI3K/AKT/mTOR signaling pathway

    Shengwen Wang, Gang Yang, Qian Zhang, Yanbei Zhang
    18-05-2026
    https://doi.org/10.4081/ejh.2026.4544
    181
    PDF: 163
    Supplementary: 22
    HTML: 7
  • Clinicopathological assessment of PD-1/PD-L1 immune checkpoint expression in desmoid tumors

    Kazuhiko Hashimoto, Shunji Nishimura, Yu Shinyashiki, Tomohiko Ito, Ryosuke Kakinoki, Masao Akagi
    26-04-2023
    https://doi.org/10.4081/ejh.2023.3688
    957
    PDF: 655
    HTML: 23
  • Peribiliary gland damage due to liver transplantation involves peribiliary vascular plexus and vascular endothelial growth factor

    Antonio Franchitto, Diletta Overi, Romina Mancinelli, Anna Paola Mitterhofer, Paolo Muiesan, Francesca Tinti, Ilaria Umbro, Stefan G. Hubscher, Paolo Onori, Eugenio Gaudio, Guido Carpino
    10-05-2019
    https://doi.org/10.4081/ejh.2019.3022
    2508
    PDF: 793
    Supplementary: 285
    HTML: 17
  • Pretreatment with interleukin-15 attenuates inflammation and apoptosis by inhibiting NF-κB signaling in sepsis-induced myocardial dysfunction

    Chaojie He, Yi Yu, Feifan Wang, Wudi Li, Hui Ni, Meixiang Xiang
    29-04-2024
    https://doi.org/10.4081/ejh.2024.4019
    1944
    PDF: 715
    HTML: 28
  • Effects mediated by the α7 nicotinic acetylcholine receptor on cell proliferation and migration in rat adipose-derived stem cells

    Marta Pernarella, Roberta Piovesana, Carlo Matera, Alessandro Faroni, Mario Fiore, Luciana Dini, Adam J. Reid, Clelia Dallanoce, Ada Maria Tata
    30-10-2020
    https://doi.org/10.4081/ejh.2020.3159
    1597
    PDF: 648
    HTML: 18
  • E-cadherin inhibits the proliferation and migration of human colorectal cancer cells through Hippo signaling pathway

    Zhijing Wang, Xiaohua Qin, Shanshan Liu, Yilei Wen, Bikan Lan, Hantao Liao, Haixian Wei
    26-05-2025
    https://doi.org/10.4081/ejh.2025.4196
    1232
    PDF: 545
    HTML: 20
  • Immunohistochemical expression of heparanase isoforms and syndecan-1 proteins in colorectal adenomas

    J. Waisberg, T.R. Theodoro, L.L. Matos, F.B. Orlandi, R.L. Serrano, G.T. Saba, M.A.S. Pinhal
    17-02-2016
    https://doi.org/10.4081/ejh.2016.2590
    2454
    PDF: 789
    HTML: 468
  • miR-29a-3p enhances the radiosensitivity of oral squamous cell carcinoma cells by inhibiting ADAM12

    Cuihong Jiang, Feng Liu , Shuai Xiao, Lili He, Wenqiong Wu, Qi Zhao
    27-09-2021
    https://doi.org/10.4081/ejh.2021.3295
    1427
    PDF: 988
    HTML: 29
  • Effect of retinoic acid on the nitrergic innervation of meibomian glands in rats

    A. Bolekova, D. Kluchova, L. Tomasova, N. Hvizdosova
    e50
    30-11-2012
    https://doi.org/10.4081/ejh.2012.e50
    1563
    PDF: 724
    HTML: 425
  • Immunofluorescence characterization of innervation and nerve-immune cell interactions in mouse lymph nodes

    Dailun Hu, Philip K. Nicholls, Melissa Claus, Yongkang Wu, Zhongli Shi, Wayne K. Greene, Bin Ma
    18-10-2019
    https://doi.org/10.4081/ejh.2019.3059
    2812
    PDF: 1596
    Supplementary: 194
    HTML: 23
  • Solamargine inhibited the progression of non-small cell lung cancer in vitro by activating T cells

    Changchun Zhang, Yichen Sun, Wei Jiang, Lin Wu, Qi Fang, Qikun Wang
    01-09-2025
    https://doi.org/10.4081/ejh.2025.4217
    538
    PDF: 221
    HTML: 11
  • RNA therapeutics - Function, design and delivery

    Carlo Alberto Redi
    br7
    17-06-2011
    https://doi.org/10.4081/ejh.2011.br7
    928
    PDF: 450
    HTML: 175
  • DPY30 promotes the growth and survival of osteosarcoma cell by regulating the PI3K/AKT signal pathway

    Gong Cheng, Fengmin An, Zhilin Cao, Mingdi Zheng, Zhongyuan Zhao, Hao Wu
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3413
    1308
    PDF: 654
    Supplementary: 109
    HTML: 35
  • Alcian blue staining to track the intracellular fate of hyaluronic-acid-based nanoparticles at transmission electron microscopy

    Flavia Carton, Mathieu Repellin, Giovanna Lollo, Manuela Malatesta
    12-12-2019
    https://doi.org/10.4081/ejh.2019.3086
    2333
    PDF: 1108
    HTML: 23
  • Identification of mechanism of the oncogenic role of FGFR1 in papillary thyroid carcinoma

    Xiong Bing Li, Jia Li Li, Chao Wang, Yong Zhang, Jing Li
    22-07-2024
    https://doi.org/10.4081/ejh.2024.4048
    2421
    PDF: 1350
    HTML: 22
  • Cancer cell-derived exosomal miR-34a inhibits the malignant progression of pancreatic adenocarcinoma cells by restraining the M2 polarization of macrophages

    Kui Long, Xiang Kui, Qingbin Zeng, Wenzhi Dong
    17-04-2025
    https://doi.org/10.4081/ejh.2025.4176
    1424
    PDF: 631
    Supplementary: 113
    HTML: 47
  • Low ozone concentrations do not exert cytoprotective effects on tamoxifen-treated breast cancer cells in vitro

    Chiara Rita Inguscio, Flavia Carton, Barbara Cisterna, Manuela Rizzi, Francesca Boccafoschi, Gabriele Tabaracci, Manuela Malatesta
    09-09-2024
    https://doi.org/10.4081/ejh.2024.4106
    1935
    PDF: 307
    HTML: 14
  • Combined lectin- and immuno-histochemistry (CLIH) for applications in cell biology and cancer diagnosis: Analysis of human urothelial carcinomas

    Daša Zupančič, Mateja Erdani Kreft, Igor Sterle, Rok Romih
    01-07-2020
    https://doi.org/10.4081/ejh.2020.3141
    1528
    PDF: 832
    Supplementary: 217
    HTML: 21
  • microRNA-16-5p suppresses cell proliferation and angiogenesis in colorectal cancer by negatively regulating forkhead box K1 to block the PI3K/Akt/mTOR pathway

    Xin Huang, Xuan Xu, Huajing Ke, Xiaolin Pan, Jiaoyu Ai, Ruyi Xie, Guilian Lan, Yang Hu, Yao Wu
    10-05-2022
    https://doi.org/10.4081/ejh.2022.3333
    1839
    PDF: 924
    HTML: 31
  • MiR-122-5p inhibits the epithelial mesenchymal transition of liver cancer cells by inducing hiPSCs to differentiate into hepatocyte-like cells

    Qianzhe Xing, Yanjie Xu, Ying Luo, Chenglong Li, Peng Wang, Bin Kang, Chengjun Lu
    06-05-2025
    https://doi.org/10.4081/ejh.2025.4190
    766
    PDF: 408
    HTML: 34
  • Downregulation of GMPS inhibited the proliferation of hepatocellular cancer cells via the regulation of STAT3/c-Myc pathway

    Zhibin Guo, Juan Yu, Jing Sun, Sheng Yang, Jiang Pu
    15-06-2026
    https://doi.org/10.4081/ejh.2026.4541
    102
    PDF: 101
    Supplementary: 16
    HTML: 0
  • MIAQuant, a novel system for automatic segmentation, measurement, and localization comparison of different biomarkers from serialized histological slices

    Elena Casiraghi, Mara Cossa, Veronica Huber, Licia Rivoltini, Matteo Tozzi, Antonello Villa, Barbara Vergani
    02-11-2017
    https://doi.org/10.4081/ejh.2017.2838
    2501
    PDF: 1213
    MIAQuant user Manual: 267
    MIAQuant source code: 343
    HTML: 77
  • Quercetin reverses 5-fluorouracil resistance in colon cancer cells by modulating the NRF2/HO-1 pathway

    Zhongzhu Tang, Lei Wang, Yunwang Chen, Xiaomin Zheng, Runyu Wang, Bingxue Liu, Shiqi Zhang, Huimin Wang
    07-08-2023
    https://doi.org/10.4081/ejh.2023.3719
    2107
    PDF: 1014
    HTML: 27
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
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20 April 2026
Vol. 70 No. 2 (2026)
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Huina Su et al.
21 April 2026
Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

is an Open Access, peer-reviewed journal published by PAGEPress®, Pavia, Italy. All credits and honors to PKP for their OJS.

pISSN: 1121-760X
eISSN: 2038-8306

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