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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

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  • DNA breakage detection-fluorescence in situ hybridization (DBD-FISH) in buccal cells

    E. I. Cortés-Gutiérrez, M. I. Davila-Rodríguez, J. L. Fernández, C. López-Fernández, J. Gosalvez
    e49
    28-12-2012
    https://doi.org/10.4081/ejh.2012.e49
    1534
    PDF: 545
    HTML: 213
  • The Feulgen reaction: from pink-magenta to rainbow fluorescent at the Maffo Vialli’s School of Histochemistry

    Giuliano Mazzini
    22-02-2024
    https://doi.org/10.4081/ejh.2024.3971
    1547
    PDF: 483
    HTML: 13
  • miR-129-5p regulates HMGB1/RAGE axis to inhibit pyroptosis and ameliorate cervical epithelial cell deterioration

    Huafang Wang, Dilidaer Sidike, Pan Liu, Longge Suo, Huerxidan Niyazi
    23-09-2025
    https://doi.org/10.4081/ejh.2025.4238
    427
    PDF: 328
    HTML: 11
  • A modified Verhoeff-van Gieson elastin histochemical stain to enable pulmonary arterial hypertension model characterization

    K.R. Percival, Z. A. Radi
    11-02-2016
    https://doi.org/10.4081/ejh.2016.2588
    3383
    PDF: 1289
    HTML: 1549
  • Lectins as versatile tools to explore cellular glycosylation

    Susan Brooks
    29-01-2024
    https://doi.org/10.4081/ejh.2024.3959
    2666
    PDF: 1196
    HTML: 48
  • Investigation of seasonal changes in lipid synthesis and metabolism-related genes in the oviduct of Chinese brown frog (Rana dybowskii)

    Yankun Wang, Yuning Liu, Yawei Wang, Ao Zhang, Wenqian Xie, Haolin Zhang, Qiang Weng, Meiyu Xu
    20-12-2023
    https://doi.org/10.4081/ejh.2023.3890
    1299
    PDF: 660
    HTML: 23
  • Quantification of morphology of canine circumanal gland tumors: a fractal based study

    I.C. Šoštarić-Zuckermann, K. Severin, M. Huzak, M. Hohšteter, A. Gudan Kurilj, B. Artuković, A. Džaja, Ž. Grabarević
    11-04-2016
    https://doi.org/10.4081/ejh.2016.2609
    1872
    PDF: 719
    HTML: 381
  • Atorvastatin reduces calcification in valve interstitial cells via the NF-κB signalling pathway by promoting Atg5-mediated autophagy

    Menghui Chen, Su Liu
    12-04-2024
    https://doi.org/10.4081/ejh.2024.3983
    1290
    PDF: 570
    HTML: 23
  • Histological analysis of the dermal and hypodermal layers of the face and correlation with high-frequency 24 MHz ultrasonography and elastosonography

    Sheila Veronese, Ezio Costa, Antonella Portuese, Riccardo Ossanna, Andrea Sbarbati
    12-04-2024
    https://doi.org/10.4081/ejh.2024.3912
    1508
    PDF: 807
    HTML: 20
  • Cancer stem cell markers ALDH1 and CD44+/CD24- phenotype and their prognosis impact in invasive ductal carcinoma

    Iris Rabinovich, Ana Paula Martins Sebastião, Rubens Silveira Lima, Cícero de Andrade Urban, Eduardo Schunemann Junior, Karina Furlan Anselmi, Selene Elifio-Esposito, Lucia de Noronha, Andréa Novais Moreno-Amaral
    03-09-2018
    https://doi.org/10.4081/ejh.2018.2943
    2939
    PDF: 1083
    HTML: 38
  • Vagal afferent projections from the pharyngeal jaw of the cichlid Nile tilapia (Oreochromis niloticus)

    Kosuke Imura, Akihito Takeda , Masato Endo, Masanori Nasu, Kengo Funakoshi
    21-10-2025
    https://doi.org/10.4081/ejh.2025.4248
    382
    PDF: 245
    HTML: 40
  • Immunohistochemical detection of putative pathogenetic factors in adhesions of infants: a pilot study

    Arvis Pauliņš, Anna Junga, Māra Pilmane
    10-02-2026
    https://doi.org/10.4081/ejh.2026.4438
    267
    PDF: 213
    HTML: 3
  • Identification of 5-hydroxytryptamine-producing cells by detection of fluorescence in paraffin-embedded tissue sections

    Y. Kaneko, N. Onda, Y. Watanabe, M. Shibutani
    29-09-2016
    https://doi.org/10.4081/ejh.2016.2684
    2221
    PDF: 826
    HTML: 310
  • Ferroptosis resistance cooperates with cellular senescence in the overt stage of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

    Antonella Vetuschi, Alfredo Cappariello, Paolo Onori, Eugenio Gaudio, Giovanni Latella, Simona Pompili, Roberta Sferra
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3391
    3644
    PDF: 1895
    HTML: 58
  • Management of autofluorescence in formaldehyde-fixed myocardium: choosing the right treatment

    Zhao Zhang, Hongming Fan, William Richardson, Bruce Z. Gao, Tong Ye
    02-10-2023
    https://doi.org/10.4081/ejh.2023.3812
    1935
    PDF: 1000
    Supplementary: 124
    HTML: 33
  • Characterization of PD-1/PD-L1 immune checkpoint expression in soft tissue sarcomas

    Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Masao Akagi
    02-07-2021
    https://doi.org/10.4081/ejh.2021.3203
    3104
    PDF: 932
    HTML: 32
  • Immunohistochemical analysis of YB-1 expression in the developing mouse eye

    Alexander Forian Nass, Hella Wolf, Saadettin Sel , Thomas Kalinski, Norbert Nass
    03-11-2025
    https://doi.org/10.4081/ejh.2025.4244
    1508
    PDF: 243
    HTML: 22
  • An improved and cost-effective methodology for the reduction of autofluorescence in direct immunofluorescence studies on formalin-fixed paraffin-embedded tissues

    MS Viegas, TC Martins, F Seco, A do Carmo
    59-66
    30-06-2009
    https://doi.org/10.4081/1013
    2122
    PDF: 1688
  • Ontogenic development of corticotrophs in fetal buffalo (Bubalus bubalis) pituitary gland

    M. A. Sandhu, A. A. Saeed, M. S. Khilji, R. H. Pasha, N. Mukhtar, M. S. Anjum
    30-01-2014
    https://doi.org/10.4081/ejh.2014.2292
    3393
    PDF: 687
    HTML: 629
  • Folic acid promotes autophagy to relieve metabolism-associated fatty liver disease by regulating NRF2

    Yu Wen, Juan Luo, Chunjing Shi, Jie Wu
    03-11-2025
    https://doi.org/10.4081/ejh.2025.4309
    820
    PDF: 538
    HTML: 33
  • Immunohistochemical expression and clinicopathological assessment of PD-1, PD-L1, NY-ESO-1, and MAGE-A4 expression in highly aggressive soft tissue sarcomas

    Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Ryosuke Kakinoki, Masao Akagi
    22-04-2022
    https://doi.org/10.4081/ejh.2022.3393
    1301
    PDF: 713
    HTML: 24
  • The matrix stiffness is increased in the eutopic endometrium of adenomyosis patients: a study based on atomic force microscopy and histochemistry

    Xiaowen Wang, Wenbin Cai, Ting Liang, Hui Li, Yingjie Gu, Xiaojiao Wei, Hong Zhang, Xiaojun Yang
    04-12-2024
    https://doi.org/10.4081/ejh.2024.4131
    1932
    PDF: 490
    HTML: 55
  • Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice

    Nana Bao, Min Zhang, Ming Tang, Ziyi Shen, Shenglin Wang, Guohui Jiang
    20-04-2026
    https://doi.org/10.4081/ejh.2026.4548
    355
    PDF: 252
    Raw data: 38
    HTML: 14
  • Clinicopathological assessment of PD-1/PD-L1 immune checkpoint expression in desmoid tumors

    Kazuhiko Hashimoto, Shunji Nishimura, Yu Shinyashiki, Tomohiko Ito, Ryosuke Kakinoki, Masao Akagi
    26-04-2023
    https://doi.org/10.4081/ejh.2023.3688
    906
    PDF: 536
    HTML: 21
  • Histological and histochemical characterization of the musk gland in forest musk deer (Moschus berezovskii): a preliminary study

    Qianyi Wang, Chunyu Han, Dong Zhang, Yuning Liu, Yunyun Gao, Haolin Zhang, Defu Hu
    10-07-2025
    https://doi.org/10.4081/ejh.2025.4216
    605
    PDF: 338
    HTML: 41
  • Mucosubstances in the porcine gastrointestinal tract: Fixation, staining and quantification

    Juliane Rieger, Barbara Drewes, Hana Hünigen, Johanna Plendl
    24-06-2019
    https://doi.org/10.4081/ejh.2019.3030
    1592
    PDF: 883
    HTML: 35
  • Degenerative effects in rat eyes after experimental ocular hypertension

    G. Scarsella, M. Nebbioso, S. Stefanini, N. Pescosolido
    e42
    08-10-2012
    https://doi.org/10.4081/ejh.2012.e42
    1540
    PDF: 595
    HTML: 202
  • Guilu Erxian oral liquid mitigates oxidative damage in spermatogonial cells via miR-6739-5p modulation and PI3K/AKT pathway activation: a functional histocytochemical study

    Zefeng Sun, Xinrong Fan, Zhenquan Liu
    02-10-2025
    https://doi.org/10.4081/ejh.2025.4253
    384
    PDF: 338
    HTML: 37
  • Mammaglobin, GATA-binding protein 3 (GATA3), and epithelial growth factor receptor (EGFR) expression in different breast cancer subtypes and their clinical significance

    Xin Kong, Qi Wang, Jie Li, Ming Li, Fusheng Deng, Chuanying Li
    07-04-2022
    https://doi.org/10.4081/ejh.2022.3315
    1596
    PDF: 802
    Supplementary: 154
    HTML: 17
  • Effect of Danggui Buxue decoction on hypoxia-induced injury of retinal Müller cells in vitro

    Xilin Ge, Caoxin Huang, Wenting Chen, Chen Yang, Wenfang Huang, Jia Li, Shuyu Yang
    25-11-2024
    https://doi.org/10.4081/ejh.2024.4140
    2000
    PDF: 635
    HTML: 26
  • Immunohistochemical expression of heparanase isoforms and syndecan-1 proteins in colorectal adenomas

    J. Waisberg, T.R. Theodoro, L.L. Matos, F.B. Orlandi, R.L. Serrano, G.T. Saba, M.A.S. Pinhal
    17-02-2016
    https://doi.org/10.4081/ejh.2016.2590
    2411
    PDF: 772
    HTML: 464
  • SRSF3 promotes the generation of XBP1s to stabilize autophagy and enhance hypoxia adaptation in glioma

    Bohu Liu, Xiaoran Zhang, Jintao Tian, Xiaobin Huang, Xuhui Li, Jinxi Zhao, Zhenghu Xu, Jun Pu
    03-03-2026
    https://doi.org/10.4081/ejh.2026.4530
    480
    PDF: 372
    HTML: 8
  • SerpinB3 administration protects liver against ischemia-reperfusion injury

    Cristian Turato, Mariapia Vairetti, Marta Cagna, Alessandra Biasiolo, Andrea Ferrigno, Santina Quarta, Mariagrazia Ruvoletto, Silvia De Siervi, Patrizia Pontisso, Laura Giuseppina Di Pasqua
    28-10-2022
    https://doi.org/10.4081/ejh.2022.3561
    1312
    PDF: 756
    HTML: 34
  • Targeting EphA2 suppresses the proliferation, migration and invasion of endometriosis via the AMPK signaling pathway

    Chaoyi Yang, Shujun Wang, Mengru Li, Xiangli Pang, Aili Tan
    17-06-2025
    https://doi.org/10.4081/ejh.2025.4168
    549
    PDF: 341
    HTML: 15
  • Dipeptidylpeptidase-­IV, a key enzyme for the degradation of incretins and neuropeptides: activity and expression in the liver of lean and obese rats

    E. Tarantola, V. Bertone, G. Milanesi, E. Capelli, A. Ferrigno, D. Neri, M. Vairetti, S. Barni, I. Freitas
    e41
    08-10-2012
    https://doi.org/10.4081/ejh.2012.e41
    1743
    PDF: 857
    HTML: 1086
  • How to stain nucleic acids and proteins in Miller spreads

    Lorena Zannino, Marco Biggiogera
    25-02-2022
    https://doi.org/10.4081/ejh.2022.3364
    2090
    PDF: 539
    HTML: 51
  • Developmental characteristics of cutaneous telocytes in late embryos of the silky fowl

    Hao Li, Junliang Chen, Wenjun You, Yizhen Xu, Yaqiong Ye, Haiquan Zhao, Junxing Li, Hui Zhang
    15-10-2024
    https://doi.org/10.4081/ejh.2024.4089
    1700
    PDF: 373
    HTML: 10
  • Characterizing the activation of the Wnt signaling pathway in hilar cholangiocarcinoma using a tissue microarray approach

    W. Chen, J. Liang, L. Huang, J. Cai, Y. Lei, J. Lai, L. Liang, K. Zhang
    09-02-2016
    https://doi.org/10.4081/ejh.2016.2536
    1865
    PDF: 858
    HTML: 342
  • Back to the future: improving storage of Golgi-stained mouse brain

    Fabrizio De Luca
    05-03-2026
    https://doi.org/10.4081/ejh.2026.4532
    337
    PDF: 229
    HTML: 20
  • Glyphosate, AMPA and glyphosate-based herbicide exposure leads to GFAP, PCNA and caspase-3 increased immunoreactive area on male offspring rat hypothalamus

    Ewing Duque-Díaz, Hernán Hurtado Giraldo, Linda P. Rocha-Muñoz, Rafael Coveñas
    13-10-2022
    https://doi.org/10.4081/ejh.2022.3428
    1829
    HTML: 69
    PDF: 810
  • Tanshinone IIA attenuates hepatic stellate cell activation, oxidative stress, and liver fibrosis by inhibiting YAP signaling

    Dan Wang, Qingquan Tan, Qing Zheng, Yanling Ma, Li Feng
    17-06-2025
    https://doi.org/10.4081/ejh.2025.4218
    1323
    PDF: 552
    HTML: 26
  • Comparison of different histological protocols for the preservation and quantification of the intestinal mucus layer in pigs

    Ilen Röhe, Friedrich Joseph Hüttner, Johanna Plendl, Barbara Drewes, Jürgen Zentek
    05-02-2018
    https://doi.org/10.4081/ejh.2018.2874
    4087
    PDF: 1748
    HTML: 268
  • A spectrofluorometric analysis to evaluate transcutaneous biodistribution of fluorescent nanoparticulate gel formulations

    Enrica Cappellozza, Federico Boschi, Maddalena Sguizzato, Elisabetta Esposito, Rita Cortesi, Manuela Malatesta, Laura Calderan
    07-02-2022
    https://doi.org/10.4081/ejh.2022.3321
    1671
    PDF: 669
    HTML: 23
  • Low ozone concentrations do not exert cytoprotective effects on tamoxifen-treated breast cancer cells in vitro

    Chiara Rita Inguscio, Flavia Carton, Barbara Cisterna, Manuela Rizzi, Francesca Boccafoschi, Gabriele Tabaracci, Manuela Malatesta
    09-09-2024
    https://doi.org/10.4081/ejh.2024.4106
    1710
    PDF: 298
    HTML: 11
  • Sox9 expression in canine epithelial skin tumors

    E. Fantinato, L. Milani, G. Sironi
    09-07-2015
    https://doi.org/10.4081/ejh.2015.2514
    3155
    PDF: 878
    HTML: 406
  • Imaging and spectral analysis of autofluorescence patterns in larval head structures of mosquito vectors

    Francesca Scolari, Alessandro Girella, Anna Cleta Croce
    20-09-2022
    https://doi.org/10.4081/ejh.2022.3462
    1664
    PDF: 602
    HTML: 58
  • Knockdown of miR-411-3p induces M2 macrophage polarization and promotes colorectal cancer progression by regulation of MMP7

    Tianliang Bai, Ping Li, Yabin Liu, Bindan Cai, Gang Li, Wenbin Wang, Rui Yan, Xiangkui Zheng, Shangkun Du
    05-05-2025
    https://doi.org/10.4081/ejh.2025.4178
    887
    PDF: 391
    Supplementary: 49
    HTML: 48
  • Histochemistry through the years, browsing a long-established journal: novelties in traditional subjects

    C. Pellicciari
    e51
    16-12-2010
    https://doi.org/10.4081/ejh.2010.e51
    1495
    PDF: 733
    HTML: 3892
  • IMAGING THE LYSOSOME IN CELLULAR SYSTEMS FOR DRUG DISCOVERY AND SCREENING V.A. Baldassarro1, M. Galeotti2, E. Satanassi3, L. Giardino1, L. Calzà4, C. Quadalti4 | 1DIMEVET, University of Bologna, Italy; 2IRET Foundation, Ozzano dell’Emilia, Bologna, Italy; 3Interdepartmental Centre for Industrial Research in Health Sciences and Technology ICIR-HST, University of Bologna, Ozzano dell’Emilia, Bologna, Italy; 4Fabit, University of Bologna, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4308
    289
  • Evaluation of biocompatibility, osteointegration and biomechanical properties of the new Calcemex® cement: An in vivo study

    Tommaso Maluta, Umberto Lavagnolo, Lydia Segalla, Nicholas Elena, Paolo Bernardi, Daniele Degl'Innocenti, Andrea Sbarbati, Bruno Magnan
    27-01-2022
    https://doi.org/10.4081/ejh.2022.3313
    1481
    PDF: 632
    HTML: 23
  • Identification of mechanism of the oncogenic role of FGFR1 in papillary thyroid carcinoma

    Xiong Bing Li, Jia Li Li, Chao Wang, Yong Zhang, Jing Li
    22-07-2024
    https://doi.org/10.4081/ejh.2024.4048
    2094
    PDF: 1088
    HTML: 19
  • Infection with CagA-positive Helicobacter pylori strain containing three EPIYA C phosphorylation sites is associated with more severe gastric lesions in experimentally infected Mongolian gerbils (Meriones unguiculatus)

    M. Ferreira Júnior, S.A. Batista, P.V.T. Vidigal, A.A.C. Cordeiro, F.M.S. Oliveira, L.O. Prata, A.E.T. Diniz, C.M. Barral, R.C. Barbuto, A.D. Gomes, I.D. Araújo, D.M.M. Queiroz, M.V. Caliari
    27-04-2015
    https://doi.org/10.4081/ejh.2015.2489
    2185
    PDF: 789
    Supplementary: 318
    HTML: 564
  • Histopathological and immunofluorescent characterization of post-sepsis immune dysregulation in a clinically relevant mouse model

    Haoran Tang, Chen Liao, Ning Tang, Hui Li, Yi Liu, Lingling Wang, Zongfang Ren
    12-02-2026
    https://doi.org/10.4081/ejh.2026.4435
    472
    PDF: 334
    HTML: 11
  • Anatomical insights into the proximal aponeurosis of the long head of the biceps femoris

    Carmela Julia Mantecón-Tagarro, Eri Nanizawa, Munekazu Naito, Shun Otsuka, Huub Maas, Yasuo Kawakami
    13-05-2025
    https://doi.org/10.4081/ejh.2025.4165
    907
    PDF: 493
    HTML: 36
  • The Bromodomain testis-specific gene (Brdt) characterization and expression in gilthead seabream, Sparus aurata, and European seabass, Dicentrarchus labrax

    M. Úbeda-Manzanaro, J.B. Ortiz-Delgado, C. Sarasquete
    02-05-2016
    https://doi.org/10.4081/ejh.2016.2638
    1718
    PDF: 821
    HTML: 335
  • Transgenesis techniques - Principles and protocols

    CarloAlberto Redi
    e28
    07-06-2010
    https://doi.org/10.4081/ejh.2010.e28
    1088
    PDF: 528
    HTML: 193
  • Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

    Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou
    06-08-2025
    https://doi.org/10.4081/ejh.2025.4228
    1162
    PDF: 533
    HTML: 18
  • Adipose mesenchymal stem cells-derived extracellular vesicles exert their preferential action in damaged central sites of SOD1 mice rather than peripherally

    Ermanna Turano, Federica Virla, Ilaria Scambi, Sylwia Dabrowska, Oluwamolakun Bankole, Raffaella Mariotti
    04-07-2024
    https://doi.org/10.4081/ejh.2024.4040
    2031
    PDF: 609
    HTML: 20
  • Effects of lead pollution on Ammonia parkinsoniana (foraminifera): ultrastructural and microanalytical approaches

    F. Frontalini, D. Curzi, F.M. Giordano, J.M. Bernhard, E. Falcieri, R. Coccioni
    30-01-2015
    https://doi.org/10.4081/ejh.2015.2460
    2502
    PDF: 867
    HTML: 1119
  • Clinicopathological assessment of cancer/testis antigens NY‑ESO‑1 and MAGE‑A4 in osteosarcoma

    Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Naohiro Oka, Ryosuke Kakinoki, Masao Akagi
    23-06-2022
    https://doi.org/10.4081/ejh.2022.3377
    1737
    PDF: 880
    HTML: 24
  • Independent and interactive roles of hirudin and HMGB1 interference in protecting renal function by regulating autophagy, apoptosis, and kidney injury in chronic kidney disease

    Ying Li, Xuan Gao, Yao Chen, Huihui Li, Jing Tang, Wei Sun
    07-04-2025
    https://doi.org/10.4081/ejh.2025.4182
    1173
    PDF: 704
    HTML: 44
  • Dexmedetomidine attenuates neuroinflammation and microglia activation in LPS-stimulated BV2 microglia cells through targeting circ-Shank3/miR-140-3p/TLR4 axis

    Guangbao He, Yibo He, Hongwei Ni, Kai Wang, Yijun Zhu, Yang Bao
    26-07-2023
    https://doi.org/10.4081/ejh.2023.3766
    1994
    PDF: 1268
    HTML: 16
  • NR4A3 suppresses bladder cancer progression by modulating autophagy via the PI3K/AKT/mTOR pathway

    Li Fan, Feng Xu, Shouyong Liu, Ding Wu, Suchun Wang, Xin Pan, Yulin Zhou, Le Qu, Wenquan Zhou
    30-06-2025
    https://doi.org/10.4081/ejh.2025.4221
    890
    PDF: 454
    HTML: 17
  • Ion channels alterations in the forebrain of high-fat diet fed rats

    Proshanta Roy, Ilenia Martinelli, Michele Moruzzi, Federica Maggi, Consuelo Amantini, Maria Vittoria Micioni Di Bonaventura, Carlo Cifani, Francesco Amenta, Seyed Khosrow Tayebati, Daniele Tomassoni
    23-11-2021
    https://doi.org/10.4081/ejh.2021.3305
    2196
    PDF: 1092
    HTML: 39
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
Nana Bao et al.
20 April 2026
Vol. 70 No. 2 (2026)
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells
Huina Su et al.
21 April 2026
Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

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