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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

1.9
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1.9
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  • Imaging techniques in nanomedical research

    Laura Calderan, Manuela Malatesta
    01-07-2020
    https://doi.org/10.4081/ejh.2020.3151
    2096
    PDF: 838
    HTML: 24
  • Transmission electron microscopy for nanomedicine: novel applications for long-established techniques

    Manuela Malatesta
    09-12-2016
    https://doi.org/10.4081/ejh.2016.2751
    2445
    PDF: 1548
    HTML: 268
  • Assessing the interactions between nanoparticles and biological barriers in vitro: a new challenge for microscopy techniques in nanomedicine

    Flavia Carton, Manuela Malatesta
    24-11-2022
    https://doi.org/10.4081/ejh.2022.3603
    1191
    PDF: 494
    HTML: 22
  • Fluorescence and electron microscopy to visualize the intracellular fate of nanoparticles for drug delivery

    M. Costanzo, F. Carton, A. Marengo, G. Berlier, B. Stella, S. Arpicco, M. Malatesta
    14-04-2016
    https://doi.org/10.4081/ejh.2016.2640
    3284
    PDF: 1413
    HTML: 600
  • Diaminobenzidine photoconversion is a suitable tool for tracking the intracellular location of fluorescently labelled nanoparticles at transmission electron microscopy

    M. Malatesta, M. Giagnacovo, M. Costanzo, B. Conti, I. Genta, R. Dorati, V. Galimberti, M. Biggiogera, C. Zancanaro
    e20
    16-04-2012
    https://doi.org/10.4081/ejh.2012.20
    1876
    PDF: 1035
    HTML: 4363
  • Histochemistry for nanomedicine: Novelty in tradition

    Manuela Malatesta
    27-12-2021
    https://doi.org/10.4081/ejh.2021.3376
    1188
    PDF: 499
    HTML: 21
  • Embedding cell monolayers to investigate nanoparticle-plasmalemma interactions at transmission electron microscopy

    Manuela Costanzo, Manuela Malatesta
    28-03-2019
    https://doi.org/10.4081/ejh.2019.3026
    1820
    PDF: 805
    HTML: 47
  • Energy Dispersive X-ray (EDX) microanalysis: A powerful tool in biomedical research and diagnosis

    Manuel Scimeca, Simone Bischetti, Harpreet Kaur Lamsira, Rita Bonfiglio, Elena Bonanno
    15-03-2018
    https://doi.org/10.4081/ejh.2018.2841
    15295
    PDF: 7260
    HTML: 515
  • Internalized chitosan nanoparticles persist for long time in cultured cells

    M. Malatesta, S. Grecchi, E. Chiesa, B. Cisterna, M. Costanzo, C. Zancanaro
    18-02-2015
    https://doi.org/10.4081/ejh.2015.2492
    2296
    PDF: 950
    HTML: 450
  • A new method for the direct tracking of in vivo lignin nanocapsules in Eragrostis tef (Poaceae) tissues

    Sara Falsini, Corrado Tani, Silvia Schiff, Cristina Gonnelli, Ilaria Clemente, Sandra Ristori, Alessio Papini
    26-03-2020
    https://doi.org/10.4081/ejh.2020.3112
    2119
    PDF: 664
    HTML: 22
  • Overview of the optical properties of fluorescent nanoparticles for optical imaging

    Federico Boschi, Francesco De Sanctis
    29-08-2017
    https://doi.org/10.4081/ejh.2017.2830
    1843
    PDF: 841
    HTML: 76
  • Alcian blue staining to track the intracellular fate of hyaluronic-acid-based nanoparticles at transmission electron microscopy

    Flavia Carton, Mathieu Repellin, Giovanna Lollo, Manuela Malatesta
    12-12-2019
    https://doi.org/10.4081/ejh.2019.3086
    2362
    PDF: 1140
    HTML: 23
  • An ex vivo experimental system to track fluorescent nanoparticles inside skeletal muscle

    Laura Calderan, Flavia Carton, Ilaria Andreana, Valeria Bincoletto, Silvia Arpicco, Barbara Stella, Manuela Malatesta
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3596
    1276
    PDF: 687
    HTML: 40
  • A spectrofluorometric analysis to evaluate transcutaneous biodistribution of fluorescent nanoparticulate gel formulations

    Enrica Cappellozza, Federico Boschi, Maddalena Sguizzato, Elisabetta Esposito, Rita Cortesi, Manuela Malatesta, Laura Calderan
    07-02-2022
    https://doi.org/10.4081/ejh.2022.3321
    1725
    PDF: 696
    HTML: 25
  • In vivo imaging techniques: a new era for histochemical analysis

    A. Busato, P. Fumene Feruglio, P.P. Parnigotto, P. Marzola, A. Sbarbati
    28-11-2016
    https://doi.org/10.4081/ejh.2016.2725
    2113
    PDF: 925
    HTML: 285
  • Simultaneous ultrastructural analysis of fluorochrome-photoconverted diaminobenzidine and gold immunolabeling in cultured cells

    M. Malatesta, C. Zancanaro, M. Costanzo, B. Cisterna, C. Pellicciari
    e26
    16-09-2013
    https://doi.org/10.4081/ejh.2013.e26
    2472
    PDF: 698
    HTML: 306
  • Elemental analysis of histological specimens: a method to unmask nano asbestos fibers

    M. Scimeca, A. Pietroiusti, F. Milano, L. Anemona, A. Orlandi, L.T. Marsella, E. Bonanno
    01-02-2016
    https://doi.org/10.4081/ejh.2016.2573
    2543
    PDF: 1645
    HTML: 409
  • Image by <a href="https://pixabay.com/users/spotsoflight-6345617/?utm_source=link-attribution&amp;utm_medium=referral&amp;utm_campaign=image&amp;utm_content=2744729">Monika Robak</a> from <a href="https://pixabay.com//?utm_source=link-attribution&amp;utm_medium=referral&amp;utm_campaign=image&amp;utm_content=2744729">Pixabay</a>

    The contribution of immunohistochemistry to the development of hydrogels for skin repair and regeneration

    Flavia Carton
    23-02-2023
    https://doi.org/10.4081/ejh.2023.3679
    2015
    PDF: 1006
    HTML: 47
  • Ultrastructural histochemistry in biomedical research: Alive and kicking

    Manuela Malatesta
    07-11-2018
    https://doi.org/10.4081/ejh.2018.2990
    2000
    PDF: 744
    HTML: 31
  • Comparison between Lipofectamine RNAiMAX and GenMute transfection agents in two cellular models of human hepatoma

    Clarissa Berardo, Veronica Siciliano, Laura G. Di Pasqua, Plinio Richelmi, Mariapia Vairetti, Andrea Ferrigno
    06-08-2019
    https://doi.org/10.4081/ejh.2019.3048
    3164
    PDF: 1961
    HTML: 36
  • 59 | ZEBRAFISH EMBRYOS AS A MODEL FOR IN VIVO EVALUATION OF NANOPARTICLE AND VESICLE BASED DELIVERY SYSTEMS A. Piersanti1, A. Tesoriere1, F. Sernesi1, S. Pozzo2, Grigoletto3, G. Adamo4, A. Bongiovanni4, G. Pasut3, F. Mancin2, N. Tiso1, F. Argenton1 | 1Department of Biology, University of Padova, Padova, Italy; 2Department of Chemistry, University of Padova, Italy; 3Department of Pharmaceutical Sciences, University of Padova, Italy; 4Institute for Research and Biomedical Innovation (IRIB) - National Research Council of Italy (CNR), Palermo, Italy

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4677
    48
    PDF: 27
  • Is there still room for novelty, in histochemical papers?

    Carlo Pellicciari
    16-12-2016
    https://doi.org/10.4081/ejh.2016.2758
    2941
    PDF: 732
    HTML: 283
  • Histochemistry as an irreplaceable approach for investigating functional cytology and histology

    C. Pellicciari
    e41
    19-12-2013
    https://doi.org/10.4081/ejh.2013.e41
    3427
    PDF: 935
    HTML: 409
  • 15 | BEYOND SURVIVAL: INNATE IMMUNE READOUTS IN ZEBRAFISH FOR ADVANCED BIOMATERIALS ASSESSMENT. C. Bragato, P. Bonfanti, A. Colombo, M. Gualtieri, P. Mantecca | Dept. of Earth and Environmental Sciences, University of Milano-Bicocca, Italy

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4633
    186
    PDF: 39
  • Histochemistry as a versatile research toolkit in biological research, not only an applied discipline in pathology

    Carlo Pellicciari
    21-12-2018
    https://doi.org/10.4081/ejh.2018.3006
    2180
    PDF: 826
    HTML: 28
  • Immunocytochemical detection of dentin matrix proteins in primary teeth from patients with dentinogenesis imperfecta associated with osteogenesis imperfecta

    G. Orsini, A. Majorana, A. Mazzoni, A. Putignano, M. Falconi, A. Polimeni, L. Breschi
    01-12-2014
    https://doi.org/10.4081/ejh.2014.2405
    2272
    PDF: 1309
    HTML: 550
  • 49 | TWEEN 60-COATED COPPER NANOPARTICLES FOR BIOMEDICAL APPLICATION: CHARACTERIZATION AND IN VITRO EVALUATION S. Mariano1|2, S.C. Resta3, G.C. Carbone1|2, A. Talà3, D. Manno1|2, A. Serra1|2, G. Quarta1|2, E. Panzarini3, L. Calcagnile1|2 | 1Department of Mathematics and Physics, University of Salento, Lecce, Italy; 2CEDAD (Center of Applied Physics, Datation and Diagnostics), Department of Mathematics and Physics, University of Salento, Lecce, Italy; 3Department of Biological and Environmental Sciences and Technologies (Di.S.Te.B.A.), University of Salento, Lecce, Italy

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4667
    89
    PDF: 29
  • Fine structural detection of calcium ions by photoconversion

    V. Poletto, V. Galimberti, G. Guerra, V. Rosti, F. Moccia, M. Biggiogera
    10-08-2016
    https://doi.org/10.4081/ejh.2016.2695
    1832
    PDF: 783
    Supplementary: 312
    HTML: 139
  • Visualizing endocytotic pathways at transmission electron microscopy via diaminobenzidine photo-oxidation by a fluorescent cell-membrane dye

    S. Grecchi, M. Malatesta
    22-10-2014
    https://doi.org/10.4081/ejh.2014.2449
    2554
    PDF: 1051
    Supplementary: 314
    HTML: 717
  • Changes in subcellular localization of visfatin in human colorectal HCT-116 carcinoma cell line after cytochalasin B treatment

    R.J. Bułdak, M. Skonieczna, Ł. Bułdak, N. Matysiak, Ł. Mielańczyk, G. Wyrobiec, M. Kukla, M. Michalski, K. Żwirska-Korczala
    12-09-2014
    https://doi.org/10.4081/ejh.2014.2408
    2143
    PDF: 831
    HTML: 580
  • FLOW CYTOMETRY FOR THE ANALYSIS OF MICRO/ NANOPARTICLES: CURRENT APPLICATIONS AND CHALLENGES S. Amalfitano | National Research Council of Italy - Water Research Institute (CNR-IRSA) – Montelibretti, Rome, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4301
    210
  • Dentin matrix protein 1 and dentin sialophosphoprotein in human sound and carious teeth: an immunohistochemical and colorimetric assay

    D. Martini, A. Trirè, L. Breschi, A. Mazzoni, G. Teti, M. Falconi, A. Ruggeri Jr
    e32
    29-10-2013
    https://doi.org/10.4081/ejh.2013.e32
    5930
    PDF: 1519
    HTML: 976
  • Calcified tissue histochemistry: from microstructures to nanoparticles

    E Bonucci
    1-10
    29-06-2009
    https://doi.org/10.4081/921
    1035
    PDF: 1048
  • P20 | SE4SAFE: A ONE HEALTH APPROACH TO ASSESS THE SAFETY OF BIOGENIC SELENIUM NANOPARTICLES A. Mileo1, S. Boccia2, B Sgangarella Valvano3, T. Pannulo4, F. Esposito4, L. Saviano4, G. Libralato4, M. De Falco4 | 1Dept. of Life Sciences, Health and Health Professions, Link Campus University, Rome, Italy; 2Dept. of Mental and Physical Health and Preventive Medicine, University of Campania “Luigi Vanvitelli”, Naples, Italy; 3Dept. of Medicine and Health Sciences “Vincenzo Tiberio”, University of Molise, Campobasso, Italy; 4Dept. of Biology, University of Naples Federico II, Naples, Italy

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4716
    104
    PDF: 17
  • Polydatin reverses oxidation low lipoprotein (oxLDL)-induced apoptosis of human umbilical vein endothelial cells via regulating the miR-26a-5p/BID axis

    Dajie Wang, Zhaofeng Zhou, Liang Yuan
    20-09-2022
    https://doi.org/10.4081/ejh.2022.3505
    1389
    PDF: 627
    HTML: 47
  • Tanshinone IIA attenuates hepatic stellate cell activation, oxidative stress, and liver fibrosis by inhibiting YAP signaling

    Dan Wang, Qingquan Tan, Qing Zheng, Yanling Ma, Li Feng
    17-06-2025
    https://doi.org/10.4081/ejh.2025.4218
    1560
    PDF: 605
    HTML: 30
  • Forever particles: histochemistry in the plasticene age

    Beatrice Camia, Andrea Casasco, Manuela Monti
    01-08-2025
    https://doi.org/10.4081/ejh.2025.4226
    1428
    PDF: 591
    HTML: 59
  • microRNA-16-5p suppresses cell proliferation and angiogenesis in colorectal cancer by negatively regulating forkhead box K1 to block the PI3K/Akt/mTOR pathway

    Xin Huang, Xuan Xu, Huajing Ke, Xiaolin Pan, Jiaoyu Ai, Ruyi Xie, Guilian Lan, Yang Hu, Yao Wu
    10-05-2022
    https://doi.org/10.4081/ejh.2022.3333
    2033
    PDF: 939
    HTML: 31
  • On the future contents of a small journal of histochemistry

    C. Pellicciari
    e51
    10-12-2012
    https://doi.org/10.4081/ejh.2012.e51
    2589
    PDF: 995
    HTML: 942
  • Pretreatment with interleukin-15 attenuates inflammation and apoptosis by inhibiting NF-κB signaling in sepsis-induced myocardial dysfunction

    Chaojie He, Yi Yu, Feifan Wang, Wudi Li, Hui Ni, Meixiang Xiang
    29-04-2024
    https://doi.org/10.4081/ejh.2024.4019
    1977
    PDF: 732
    HTML: 28
  • Astragaloside IV inhibits nasopharyngeal carcinoma progression by inhibiting SATB2/Wnt/PD-L1 pathway and enhancing the killing activity of T cells

    Yinping Zeng, Jiajun Huang, Tingting Duan, Xiaofeng Wang
    28-05-2026
    https://doi.org/10.4081/ejh.2026.4540
    320
    PDF: 247
    HTML: 9
  • Incubation under fluid dynamic conditions markedly improves the structural preservation in vitro of explanted skeletal muscles

    Flavia Carton, Laura Calderan, Manuela Malatesta
    28-11-2017
    https://doi.org/10.4081/ejh.2017.2862
    1670
    PDF: 655
    HTML: 115
  • Pre-treatment with galectin-1 attenuates lipopolysaccharide-induced myocarditis by regulating the Nrf2 pathway

    Liying Shen, Kongjie Lu, Zhenfeng Chen, Yingwei Zhu, Cong Zhang, Li Zhang
    07-12-2023
    https://doi.org/10.4081/ejh.2023.3816
    1232
    PDF: 720
    HTML: 37
  • Impact of Histochemistry on biomedical research: looking through the articles published in a long-established histochemical journal

    C. Pellicciari
    30-12-2014
    https://doi.org/10.4081/ejh.2014.2474
    2439
    PDF: 706
    HTML: 823
  • Ferritin expression in the periodontal tissues of primates

    Wenxue Huang, Wei Li, Juan Liu, Jianxia Hou, Huanxin Meng
    03-09-2019
    https://doi.org/10.4081/ejh.2019.3046
    1354
    PDF: 746
    HTML: 21
  • Colchicine alleviates severe acute pancreatitis in rats by inhibiting acinar cell ferroptosis via LCN2/MAPK/ERK signaling axis

    Liu Yang, Xiaoyi Zheng, Yang Zhang, Yue Li, Lei Li, Feng Liu
    11-05-2026
    https://doi.org/10.4081/ejh.2026.4557
    375
    PDF: 500
    Supplementary: 42
    HTML: 5
  • Increased number of intestinal villous M cells in levamisole - pretreated weaned pigs experimentally infected with F4ac+ enterotoxigenic Escherichia coli strain

    H. Valpotić, A. Kovšca Janjatović, G. Lacković, F. Božić, V. Dobranić, D. Svoboda, I. Valpotić, M. Popović
    e18
    01-07-2010
    https://doi.org/10.4081/ejh.2010.e18
    1651
    PDF: 647
    HTML: 1223
  • Ultrastructural analysis of different human mesenchymal stem cells after in vitro expansion: a technical review

    M. Miko, L. Danisovic, A. Majidi, I. Varga
    26-10-2015
    https://doi.org/10.4081/ejh.2015.2528
    2673
    PDF: 881
    HTML: 841
  • Long noncoding RNA H19 accelerates tenogenic differentiation by modulating miR-140-5p/VEGFA signaling

    You-Jie Liu, Hua-Jun Wang, Zhao-Wen Xue, Lek-Hang Cheang, Man-Seng Tam, Ri-Wang Li, Jie-Ruo Li, Hui-Ge Hou, Xiao-Fei Zheng
    07-09-2021
    https://doi.org/10.4081/ejh.2021.3297
    1884
    PDF: 974
    Supplementary: 176
    HTML: 27
  • Quantum dots-based multiplexed immunohistochemistry of protein expression in human prostate cancer cells

    C Shi, G Zhou, Y Zhu, Y Su, T Cheng, HE Zhau, LWK Chung
    127-134
    14-08-2009
    https://doi.org/10.4081/1202
    1116
    PDF: 1133
  • P09 | EFFECTS OF NUTLIN-3A ACTIVITY ON 2D AND 3D RETINOBLASTOMA MODELS F. Bompan1, R. Foschi2, A. Dipinto3, F. Casciano2, G. Lodi4, A. Sanvido5, P. Severi4, L. Giari1, L. C. Cosenza5, R. Voltan2, A. Romani4 | 1Department of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy; 2Department of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy; LTTA Centre, University of Ferrara, Ferrara, Italy; 3Department of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy; 4Department of Translational Medicine, University of Ferrara, Ferrara, Italy; LTTA Centre, University of Ferrara, Ferrara, Italy; 5Department of Translational Medicine, University of Ferrara, Ferrara, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4329
    192
  • Effects of lead pollution on Ammonia parkinsoniana (foraminifera): ultrastructural and microanalytical approaches

    F. Frontalini, D. Curzi, F.M. Giordano, J.M. Bernhard, E. Falcieri, R. Coccioni
    30-01-2015
    https://doi.org/10.4081/ejh.2015.2460
    2627
    PDF: 909
    HTML: 1125
  • Twenty years of histochemistry in the third millennium, browsing the scientific literature

    Carlo Pellicciari
    29-12-2020
    https://doi.org/10.4081/ejh.2020.3213
    1429
    PDF: 554
    HTML: 15
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
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20 April 2026
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Huina Su et al.
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Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
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European Journal of Histochemistry

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