71st Congress of the Italian Embryological Group-Italian Society of Development and Cell Biology (GEI-SIBSC)

• 01 | OVERCOMING HORMONAL BARRIERS TO CARDIAC REGENERATION G. D’Uva^1|2 | ¹Department of Medical and Surgical Sciences; ²IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4619

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• 02 | MODELING NON-CELL AUTONOMOUS MECHANISMS IN THE ALS PERIPHERAL NERVOUS SYSTEM A. Romano^1|2|3 | ¹Dept. of Life Sciences, Health and Health Professions, Link Campus University, Rome, Italy; ²Neuropathology Unit, Institute of Experimental Neurology, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy; ³CNR NANOTEC - Institute of Nanotechnology, Lecce, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4620

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• 03 | DISTINCTIVE HOMEOSTATIC BALANCE IN CHILDHOOD OBESITY AND ITS RELATIONSHIP WITH BONE HEALTH Maria Felicia Faienza | Pediatric Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari Aldo Moro, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4621

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• 04 | MODULATION OF NEUROINFLAMMATION IN IL-1BETA-INDUCED HUMAN ASTROCYTES: EFFECTS OF GREEN LEAVES AND RHIZOMES EXTRACT FROM POSIDONIA OCEANICA (L.) DELILE G. Abruscato¹, L. Sileo², G. Scanavino², C. Guerriero², M. Mauro¹, M. Vazzana^1|3, V. Arizza^1|3, C. Luparello^1|3, A.M.Tata² | ¹Dept. of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; ²Dept. of Biology and Biotechnologies Charles Darwin, Sapienza- University of Rome, Italy; ³National Biodiversity Future Center (NBFC), Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4622

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• 05 | MITOCHONDRIA DANCE WITH LIGHT: HOW WAVELENGTH CHOREOGRAPHS RESPIRASOMA, NITRIC OXIDE AND OXIDATIVE PHOSPHORYLATION Andrea Amaroli¹, Matilde Balbi², Silvia Ravera^2|3 | ¹Dept. of Earth, Environmental and Life Sciences, University of Genoa, Italy; ²Dept. of Experimental Medicine, University of Genoa, Italy; ³IRCCS Azienda Ospedaliera Metropolitana, Genova, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4623

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• 06 | OBESITY-INDUCED TESTICULAR DYSFUNCTION: PROTECTIVE ROLES OF THYROID HORMONES IN HIGH-FAT DIET-FED RATS M.R. Ambruosi¹, A. Biasi¹, M. Vigliotti², N. Scopigno², F. Cioffi², M. Venditti¹ | ¹Dept. Experimental Medicine, University of Campania “Luigi Vanvitelli”, Naples, Italy; ²Dept. of Science and Technology, University of Sannio, Benevento, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4624

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• 07 | FROM GUT MICROBIOTA TO GONADS: BUTYRATE MITIGATES PFAS–PESTICIDE MIXTURE TOXICITY IN ZEBRAFISH SPERMATOGENESIS M. Lombó, N. Baldoni, C. Giommi, O. Carnevali | Dept. of Life and Environmental Sciences, Polytechnic University of Marche, Ancona, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4625

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• 08 | HUMAN ADIPOSE STEM CELLS: IMPACT OF DONORS’ AGE ON CELL PROPERTIES AND BEHAVIOUR Ludovica Barone¹, Federica Rossi¹, Federico Tamborini¹, Christina Pagiatakis^1|2, Roberto Papait^1|2, Rosalba Gornati¹ | ¹Dept of Biotechnology and Life Sciences, University of Insubria, Varese, Italy; ²Dept of Cardiovascular Medicine, IRCCS Humanitas Research Hospital, Rozzano (MI), Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4626

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• 09 | MODULATION OF ETOSIS BY BIOACTIVE EXTRACTS DERIVED FROM MARINE RESOURCES AND AGRI-FOOD BY-PRODUCTS F. Bellistrì¹, G. Abruscato¹, M. Perlotti¹, A. Lo Muzzo¹, C. Gargano¹, F. Longo¹, M. Mauro¹, R. Chiarelli¹, V. Arizza^1|3, C. Luparello^1|3, G. Sarà^2|3, M. Vazzana^1|3 | ¹Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; ²Department of Earth and Marine Sciences, Palermo, Italy; ³National Biodiversity Future Center, Palermo, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4627

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• 10 | ASSESSING RECOVERY FROM HYDROCARBON SPILL EXPOSURE IN MEDITERRANEAN MUSSEL MYTILUS GALLOPROVINCIALIS: A MULTI-BIOMARKER APPROACH F. Bertini¹, L. Scirè Calabrisotto¹, L. Bisanti¹, C. La Corte¹, M. Dara¹, M. Staropoli¹, L. T. Marcianò², G. Santaluna², L. Greco¹, R. Chiarelli³, V. Catania¹, D. Parrinello¹, M. Cammarata¹, M.G. Parisi¹ | ¹Dept. of Earth and Marine Sciences, University of Palermo, Italy; ²Dept. of Earth and Marine Sciences, University of Palermo, Italy; ³Dept. of Biological, Chemical and Pharmaceutical Sciences and Technology, University of Palermo, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4628

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• 11 | FROM SIGNALING TO STRUCTURE: TYPE 1 DIABETES DISRUPTS ACTIN NETWORKS IN TESTIS AND SPERMATOZOA A. Biasi¹, M. R. Ambruosi¹, S. Falvo², S. Minucci¹, M. Venditti¹ | ¹Dept of Experimental Medicine, University of Campania “L. Vanvitelli”; ²Dept. of Environmental Biological and Pharmaceutical Sciences and Technologies, University of Campania “L. Vanvitelli”, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4629

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• 12 | IMPACT OF COCAINE ON GASTROINTESTINAL BARRIER INTEGRITY S. Boccia¹, B. Sgangarella Valvano², A. Mileo³, A. Nebbioso⁴, A. De Luca¹, A. Capaldo⁵, M. De Falco^5|6 | ¹Dept. of Mental and Physical Health and Preventive Medicine, University of Campania “Luigi Vanvitelli”, Naples, Italy; ²Dept. of Medicine and Health Sciences “Vincenzo Tiberio”, University of Molise, Campobasso, Italy; ³Dept. of Life Sciences, Health and Health Professions, Link Campus University, Rome, Italy; ⁴Dept. of Precision Medicine, University of Campania Luigi Vanvitelli, Naples, Italy; ⁵Dept. of Biology, University of Naples Federico II, Naples, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4630

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• 13 | MULTI-OMICS DISSECTION OF TRANSCRIPTIONAL AND EPIGENETIC REMODELING DURING CARDIAC AGING Daniele Bonisolo¹, Simone Serio², Christina Pagiatakis^1|2, Rosalba Gornati¹, Giovanni Bernardini¹, Roberto Papait^1|2 | ¹Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy; ²Department of Cardiovascular Medicine, IRCCS Humanitas Research Hospital, Rozzano (MI), Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4631

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• 14 | NR2F1 MODULATES ACTIVATION DYNAMICS AND MAINTENANCE OF THE ADULT MURINE HIPPOCAMPAL NEURAL STEM CELL POOL S. Bonzano^1|2, A. Lippolis^1|2, S. Quaresima³, V. Manzini³, E. Dallorto^1|2, E. Cacci³, P. Peretto^1|2, M. Studer⁴, V. Licursi⁵, G. Lupo³, S. De Marchis^1|2 | ¹Dept. of Life Sciences and Systems Biology (DBIOS), Univ. of Turin, Italy; ²Neuroscience Institute Cavalieri Ottolenghi (NICO), Orbassano (Turin), Italy; ³Dept. of Biology and Biotechnologies Charles Darwin, Sapienza Univ. of Rome, Italy; ⁴Univ. Côte d'Azur, CNRS, Inserm, iBV, Nice, France; ⁵Institute of Molecular Biology and Pathology (IBPM), National Research Council (CNR), Rome, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4632

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• 15 | BEYOND SURVIVAL: INNATE IMMUNE READOUTS IN ZEBRAFISH FOR ADVANCED BIOMATERIALS ASSESSMENT. C. Bragato, P. Bonfanti, A. Colombo, M. Gualtieri, P. Mantecca | Dept. of Earth and Environmental Sciences, University of Milano-Bicocca, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4633

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• 16 | EXTRACELLULAR VESICLES RELEASED BY CUMULUS CELLS CONTRIBUTE TO THE ACQUISITION OF MOUSE OOCYTE’S DEVELOPMENTAL COMPETENCE Giulia Brazzale¹, Mario Zanoni¹, Valeria Merico¹, Giulia Fiorentino¹, Paola Rebuzzini¹, Andrea Fantinato¹, Margherita Isernia¹, Sergio Comincini¹, Danilo Cimadomo^1|2, Maurizio Zuccotti¹ | ¹Dept. of Biology and Biotechnology, University of Pavia, Italy; ²IVIRMA Global Research Alliance, IVIRMA Italia, Rome, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4634

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• 17 | EXPLORING THE FUNCTIONAL ROLE OF THE PROTEOGLYCAN ESM1 IN THE BREAST CANCER TUMOR MICROENVIRONMENT E. Peri¹, S. Feo^1|2, E. Roz³, A. D’Ascola⁴, P. Cancemi^1|2 | ¹Department of Biological Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Italy; ²Experimental Center of Onco Biology (COBS), Palermo, Italy; ³La Maddalena Hospital III Level Oncological Department, Palermo, Italy; ⁴Department of Clinical and Experimental Medicine, University of Messina, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4635

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• 18 | EARLY-DIFFERENTIATED C2C12 MYOTUBES RELEASE A PRO-TROPHIC SECRETOME THAT MODULATES NSC-34 MATURATION: IMPLICATIONS FOR NEUROMUSCULAR CROSSTALK IN AMYOTROPHIC LATERAL SCLEROSIS E. Carata, M. Muci, E. Panzarini | Dept. of Biological and Environmental Sciences and Technologies, University of Salento, Lecce, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4636

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• 19 | ADRENERGIC MODULATION OF THE HYPOTHALAMIC-PITUITARY-THYROID AXIS IN THE LIZARD PODARCIS SICULUS Francesca Carrella¹, Assunta Lallo¹, Stefania Boccia², Maria De Falco^3|4, Rosaria Sciarrillo¹ | ¹Department of Science and Technologies, University of Sannio, Benevento, Italy; ²Department of Mental and Physical Health and Preventive Medicine, University of Campania “Luigi Vanvitelli”, Naples, Italy; ³Department of Biology, University of Naples “Federico II”, Naples, Italy; ⁴National Institute of Biostructures and Biosystems (INBB), Rome, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4637

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• 20 | REPRODUCTIVE DYNAMICS AND PHYSIOLOGICAL CONDITION IN DIFFERENT SIZE CLASSES OF COMMON SOLE (SOLEA SOLEA) FROM THE NORTH-CENTRAL ADRIATIC SEA G. Chemello¹, L. Tortora¹, C. Santoni¹, E. Giorgini¹, S. Colella², G. Gioacchini¹ | ¹Dept. of Life and Environmental Science, Polytechnic University of Marche, Italy; ²National Research Council (CNR), Institute for Marine Biological Resources and Biotechnology (IRBIM), Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4638

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• 21 | ARSENIC-INDUCED OXIDATIVE AND CELLULAR STRESS IN THE FRESHWATER SNAIL LYMNAEA STAGNALIS T. Chianese, S. Balsamo, R. Leandri, D. Modano, K. Power, R. Scudiero, A. Capaldo | Dept. of Biology, University of Naples Federico II, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4639

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• 22 | TRANSCRIPTIONAL AND POST-TRANSLATIONAL NETWORKS COORDINATE SELECTIVE AUTOPHAGY TO MAINTAIN ORGANELLE HOMEOSTASIS K. Hartfelt¹, M. Petraroia², T. Persichini², M. Colasanti², C. Di Malta³, F. Cecconi⁴, V. Cianfanelli² | ¹Unit of Cell Stress and Survival, Danish Cancer Institute, Copenhagen, Denmark; ²Dept. of Science, University Roma TRE, Rome, Italy; ³Telethon Institute of Genetics and Medicine, Naples, Italy; ⁴Dept. of Basic Biotechnological Sciences, Intensive Care and Perioperative Clinics Research, Catholic University of the Sacred Heart, Rome, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4640

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• 23 | BIOFUNCTIONALIZED ELECTROSPUN FIBERS FOR SKIN REGENERATION E. Coccia¹, R. Imperatore¹, E. Mula^1|2, M. Paolucci¹ | ¹Dept. of Sciences and Technologies, University of Sannio, Benevento, Italy; ²Dept. of Organic and Inorganic Chemistry, University of Alcalà, Alcalà de Henares, Spain

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4641

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• 24 | ADMINISTRATION OF BRANCHED-CHAIN AMINO ACIDS AND DI-ALANINE MITIGATES MUSCLE ATROPHY IN A MOUSE MODEL OF CANCER CACHEXIA M. Colardo¹, N. Martella¹, M. Varone¹, D. Pensabene¹, G. Caretti², G. Bianchini³, A. Aramini³, M. Segatto¹ | ¹Dept. of Biosciences and Territory, University of Molise, Italy; ²Dept. of Biosciences, University of Milan, Italy; ³Research & Early Development, Dompé Farmaceutici S.p.A., L’Aquila, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4642

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• 25 | ENHANCING IN VITRO FOLLICULOGENESIS THROUGH OVARIAN TISSUE-ENDOTHELIAL CELL CO-CULTURE: 3D MAPPING OF NEO-CAPILLARY GROWTH AND MATURATION V. De Gregorio¹, A. Candela¹, V. Genovese², M. Cimmino^1|2, R. Talevi¹, R. Gualtieri¹ | ¹Department of Biology, University of Naples Federico II, Naples, Italy; ²IVF RED srl, Caserta, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4643

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• 26 | ASSESSING DEVELOPMENTAL TOXICITY OF PSYCHOACTIVE POLLUTANTS USING XENOPUS LAEVIS AS A MODEL S. Di Marino, C. Fogliano, C.M. Motta, B. Avallone, R. Carotenuto | Dept. of Biology, University of Naples Federico II, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4644

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• 27 | CELLULAR AND MOLECULAR MECHANISMS OF GADOLINIUM TOXICITY IN SERTOLI CELLS Sara Falvo¹, Giulia Grillo¹, Gabriella Chieffi Baccari¹, Giuseppe Petito¹, Massimo Venditti², Maria Maddalena Di Fiore¹, Tiziana Cappello³, Maria Maisano³, Alessandra Santillo¹ | ¹Dept of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania L. Vanvitelli, Caserta, Italy; ²Dept of Experimental Medicine, University of Campania L. Vanvitelli, Napoli, Italy; ³Dept of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4645

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• 28 | 3D MORPHO-FUNCTIONAL RECONSTRUCTION OF THE PREPUBERTAL MOUSE OVARY COMBINING NANO-COMPUTED TOMOGRAPHY AND CONFOCAL IMAGING A. Fantinato^1|4, G. Fiorentino^1|4, A. Parrilli², G. Brazzale¹, V. Merico¹, P. Rebuzzini¹, D. Cimadomo^1|3, S. Garagna¹, M. Zuccotti¹ | ¹Dept. of Biology and Biotechnology, University of Pavia, Italy; ²Empa-Swiss Federal Laboratories for Materials Science and Technology, Switzerland; ³IVIRMA Global Research Alliance, Genera, Clinica Valle Giulia, Italy; ⁴Equal contribution

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4646

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• 29 | IL-17 FAMILY IN POMACEA CANALICULATA: FIRST EVIDENCE OF A EXCLUSIVE NEURAL-SPECIFIC MEMBER A. Ferri¹, S. Sacchi¹, C. Losi², N. Franchi¹, U. Rosani³, D. Malagoli^1|4 | ¹Dept. of Life Science, University of Modena and Reggio Emilia, Italy; ²Dept. of Chemical and Geological Sciences, University of Modena and Reggio Emilia, Italy; ³Dept. of Biology, University of Padova, Italy; ⁴NBFC, National Biodiversity Future Center, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4647

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• 30 | NANO-COMPUTED TOMOGRAPHY 3D MAPPING OF PRIMARY-TO-PREOVULATORY FOLLICLES IN THE MOUSE OVARY ACROSS LIFESPAN G. Fiorentino^1|9, A. Fantinato^1|9, A. Parrilli², T. Marzi³, C. Alippi^3|4, R. Bellazzi⁵, L. Rienzi^6|7, F.M. Ubaldi⁸, A. Vaiarelli⁸, G. Brazzale¹, V. Merico¹, P. Rebuzzini¹, D. Cimadomo^1|7, S. Garagna¹, M. Zuccotti¹ | ¹Dept. of Biology and Biotechnology, University of Pavia, Italy; ²Empa-Swiss Federal Laboratories for Materials Science and Technology, Switzerland; ³Faculty of Informatics, Università della Svizzera italiana, Switzerland; ⁴Dept. of Electronics, Information, and Bioengineering, Politecnico di Milano, Italy; ⁵Dept. of Computer, Electrical and Biomedical Engineering, University of Pavia, Italy; ⁶Dept. of Biomolecular Sciences, University of Urbino, Italy; ⁷IVIRMA Global Research Alliance, IVIRMA Italia, Italy; ⁸IVIRMA Global Research Alliance, Clinica Valle Giulia, Italy; ⁹Equal contribution

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4648

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• 31 | LOSS OF IMPG2 PARALOGS LEADS TO RETINAL DEGENERATION IN ZEBRAFISH DOUBLE KNOCK-OUT MODEL C. Fogliano¹, A. Cumplido Mayoral², L. Balasco², S. Casarosa^2|3, B. Avallone¹ | ¹Dept. of Biology, University of Naples Federico II, Italy ²Dept. of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Italy; ³Center for Medical Sciences, University of Trento, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4649

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• 32 | CONTROLLING COMPLEMENT FROM IMMUNITY TO DEVELOPMENT Filippo Bertolasi¹, Sandro Sacchi¹, Alessandro Vezzi², Gabriele Sales², Anita Ferri¹, Davide Malagoli^1|3, Nicola Franchi¹ | ¹Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy; ²Department of Biology, University of Padova, Italy; ³National Biodiversity Future Center (NBFC), Palermo, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4650

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• 33 | GADOLINIUM AND REPRODUCTIVE HEALTH IN NON-TARGET ORGANISMS: EVIDENCE FROM MYTILUS GALLOPROVINCIALIS SPECIES M. Galati¹, S. Falvo², G. Vinci¹, G. De Marco¹, V. Parrino¹, T. Cappello¹, A. Santillo², M. Maisano¹ | ¹Dept. of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; ²Dept. of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania L. Vanvitelli, Caserta, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4651

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• 34 | CYTOTOXIC EFFECTS OF SICILIAN GRAPE SEED OILS ON CANCER CELLS D. Ganci¹, G. Abruscato², R. Chiarelli¹, M. Mauro^1|2, V. Arizza^1|2, M. Vazzana^1|2, C. Luparello^1|2 | ¹Dept. of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Italy; ²NFBC, National Biodiversity Future Center, Palermo, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4652

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• 35 | DISSECTING THE REGIONAL ORGANIZATION OF WIRING AND VOLUME TRANSMISSION IN THE SEROTONERGIC SYSTEM G. Gianni, M. Picchi, S. Nazzi, S. Migliarini, N. Barsotti, M. Pasqualetti | Department of Biology, University of Pisa, Italy

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4653

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• 36 | A 3D HUMAN OSTEOBLAST SPHEROID MODEL REVEALS ENDOCRINE DISRUPTOR OSTEOTOXICITY AND THE EFFECTS OF POSTBIOTICS Christian Giommi^1|2, Fiorenza Sella¹, Marta Lombó^1|2|3, Oliana Carnevali^1|2 | ¹Dept. of Life and Environmental Sciences, Polytechnic University of Marche, Ancona, Italy; ²INBB-Biostructures and Biosystems National Institute, Rome, Italy; ³Dept. of Molecular Biology, Universidad de León, Spain

  GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

  https://doi.org/10.4081/ejh.2026.4654

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• 37 | INVESTIGATING THE ROLE OF NR2F1 IN NEURAL STEM CELL QUIESCENCE AND ACTIVATION IN THE ADULT SUBVENTRICULAR ZONE Iacono F.¹, Licursi V.², Quaresima S.¹, Manzini V.², Felli A.¹, Lippolis A.^3|4, Miranda Banos M.E.¹, Cacci E.¹, Peretto P.^3|4, Studer M.⁵, De Marchis S.^3|4, Lupo G.¹, Bonzano S.^3|4 | ¹Department of Biology e Biotechnologies Charles Darwin, Sapienza University of Rome, Italy; ²Institute of Molecular Biology and Pathology (IBPM), National Research Council (CNR), Rome, Italy; ³Department of Life Sciences and Systems Biology (DBIOS), University of Turin, Italy; ⁴Neuroscience Institute Cavalieri Ottolenghi (NICO), Regione Gonzole 10, Orbassano (TO), Italy; ⁵Univ. Côte d'Azur (UniCA), CNRS, Inserm, Institut de Biologie Valrose (iBV), Nice, France

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• 38 | NATURAL ANTIOXIDANTS IN THE FIGHT AGAINST OVARIAN CANCER: IN VITRO EFFECTS OF POLYPHENOLS Lorenzo Ibello, Filomena Mottola, Maria Teresa Gentile, Ilaria Palmieri, Lucia Rocco | Dipartimento di Scienze e Tecnologie Ambientali, Biologiche e Farmaceutiche, Università degli Studi della Campania “Luigi Vanvitelli”, Caserta, Italy

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• 39 | ENVIRONMENTAL FACTORS INFLUENCE THE PROTECTIVE EFFICACY OF BRASSICA OLERACEA EXTRACTS ON INTESTINAL AND HEPATIC HOMEOSTASIS IN ZEBRAFISH R. Imperatore¹, I. Šola², E. Coccia¹, R. Sciarrillo¹, M. Paolucci¹ | ¹Dept. of Sciences and Technologies, University of Sannio, Benevento, Italy; ²Department of Biology, Faculty of Science, University of Zagreb, Croatia

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  https://doi.org/10.4081/ejh.2026.4657

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• 40 | PREIMPLANTATION EMBRYO MORPHOLOGICAL FEATURES AS NON-INVASIVE MARKERS OF DEVELOPMENT TO BLASTOCYST M. Isernia^1|7, A. Fantinato^1|7, L. Corso^2|7, E. Kayar², G. Fiorentino¹, G. Nicora², M. Meseguer³, M. Taggi⁴, F. Innocenti⁴, G. Coticchio⁴, A. Vaiarelli⁵, L. Rienzi^4|6, R. Bellazzi², M. Zuccotti¹, D. Cimadomo^1|4 | ¹Dept. of Biology and Biotechnology, University of Pavia, Italy; ²Dept. of Electrical, Computer and Biomedical Engineering, University of Pavia, Italy; ³IVIRMA Global Research Alliance, IVI Valencia, Spain; ⁴IVIRMA Global Research Alliance, IVIRMA Italia, Italy; ⁵IVIRMA Global Research Alliance, Genera, Clinica Valle Giulia, Italy; ⁶Dept. of Biomolecular Sciences, University of Urbino, Italy; ⁷these authors contributed equally

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• 41 | IMPACT OF POLYETHYLENE MICROPLASTICS ON INTESTINE, OVARY AND BRAIN OF ZEBRAFISH A. La Pietra, A.R. Bianchi, B. Berman, T. Mobilio, A. Chirico, G. Imbimbo, A. De Maio, I. Ferrandino | Dept. of Biology, University of Naples Federico II, Italy

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  https://doi.org/10.4081/ejh.2026.4659

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• 42 | IMPACT OF MICROPLASTICS AND BISPHENOL A, ALONE AND ABSORBED ON MPS, ON MYTILUS EDULIS EMBRYOS G. La Pusata¹, C. Lefebvre², M. Galati¹, E. Pulvirenti³, V. Parrino¹, G.O. Conti³, M. Ferrante³, M. Maisano¹, J. Cachot², T. Cappello¹ | ¹Dept. of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; ²University of Bordeaux, Laboratory EPOC, UMR 5805, Pessac, France; ³Dept. of Medical, Surgical Sciences and Advanced Technologies G.F. Ingrassia, University of Catania, Italy

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  https://doi.org/10.4081/ejh.2026.4660

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• 43 | OVERVIEW OF EFFECTS OF ENDOCRINE-DISRUPTING CHEMICALS (EDCS) ON THE MORPHOPHYSIOLOGY OF THE THYROID GLAND IN REPTILES: EVIDENCE FROM LACERTIDE PODARCIS SICULUS Assunta Lallo¹, Francesca Carrella¹, Roberta Imperatore¹, Benedetta Sangarella Valvano⁴, Maria De Falcob³, Rosaria Sciarrillo¹ | ¹Department of Science and Technologies, University of Sannio, Benevento, Italy; ²Department of Biology, University of Naples “Federico II”, Naples, Italy; ³National Institute of Biostructures and Biosystems (INBB), Rome, Italy; ⁴Dept. of Medicine and Health Sciences “Vincenzo Tiberio”, University of Molise, Campobasso, Italy

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  https://doi.org/10.4081/ejh.2026.4661

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• 44 | CHARACTERIZATION OF IMMUNE CELLS IN THE ADIPOSE TISSUE OF OBESE MICE TREATED WITH ANTI-OBESITY THERAPIES G.P. Lombardo¹, A. Nunnari¹, A. Miller², M. Kotańska³, S. Fiorentino¹, E.R. Lauriano¹ | ¹Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Italy; ²Department for the Promotion of Human Sciences and Quality of Life, San Raffaele University, Rome, Italy; ³Department of Pharmacodynamics, Jagiellonian University, Medical College, Medyczna 9, Krakow, Poland

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  https://doi.org/10.4081/ejh.2026.4662

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• 45 | HEMOLYMPH REPOPULATION AFTER WITHDRAWAL INVOLVES CIRCULATING AND KIDNEY-RESIDENT HEMOCYTE POPULATIONS IN THE SNAIL POMACEA CANALICULATA C. Losi¹, A. Ferri², S. Sacchi², M. Montanari², G. Sansalone², D. Malagoli^2|3 | ¹Models and Methods for Material and Environmental Sciences PhD Course, Dept. of Chemical and Geological Sciences, University of Modena and Reggio Emilia, Italy; ²Dept. of Life Sciences, University of Modena and Reggio Emilia, Italy; ³NBFC-National Biodiversity Future Center, Palermo, Italy

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  https://doi.org/10.4081/ejh.2026.4663

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• 46 | DEFINING FAM46C-DEPENDENT LIPID REMODELLING IN CELLULAR HOMEOSTASIS Isidora Alempijevic¹, Federica De Grossi¹, Annarita Miluzio¹, Ivan Ferrari¹, Elisa Arsuffi¹, Marilena Mancino¹, Stefano Biffo^1|2, Nicola Manfrini^1|2 | ¹INGM, Istituto Nazionale Genetica Molecolare Romeo ed Enrica Invernizzi, Milan, Italy; ²Department of Biosciences, University of Milan, Italy

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  https://doi.org/10.4081/ejh.2026.4664

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• 47 | SYNERGISTIC LUNG TOXICITY OF PM2.5 AND ENNIATIN B1 IN A CO-CULTURE MODEL S. Marchetti¹, F. Caloni², P. Mantecca¹, M. Gualtieri¹ | ¹POLARIS Research Centre, Dept. of Earth and Environmental Sciences, University of Milano-Bicocca, Italy; ²Dept. of Environmental Science and Policy, Università degli Studi di Milano, Italy

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  https://doi.org/10.4081/ejh.2026.4665

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• 48 | ENHANCING ANGIOGENESIS IN HIRUDO VERBANA USING NANOSTRUCTURED SCAFFOLDS PRIMED WITH HUMAN DENTAL PULP STEM CELL SECRETOME G. Marcolli¹, S. Zorzetto¹, N. Baranzini^1|2, L. Pulze^1|2, L. Barone¹, F. Rossi¹, R. Gornati¹, A. Grimaldi^1|2 | ¹Dept. of Biotechnology and Life Sciences, University of Insubria, Varese, Italy; ²Italian Leech Farm (ILFARM) S.r.l, Varese, Italy

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  https://doi.org/10.4081/ejh.2026.4666

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• 49 | TWEEN 60-COATED COPPER NANOPARTICLES FOR BIOMEDICAL APPLICATION: CHARACTERIZATION AND IN VITRO EVALUATION S. Mariano^1|2, S.C. Resta³, G.C. Carbone^1|2, A. Talà³, D. Manno^1|2, A. Serra^1|2, G. Quarta^1|2, E. Panzarini³, L. Calcagnile^1|2 | ¹Department of Mathematics and Physics, University of Salento, Lecce, Italy; ²CEDAD (Center of Applied Physics, Datation and Diagnostics), Department of Mathematics and Physics, University of Salento, Lecce, Italy; ³Department of Biological and Environmental Sciences and Technologies (Di.S.Te.B.A.), University of Salento, Lecce, Italy

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  https://doi.org/10.4081/ejh.2026.4667

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• 50 | DECIPHERING THE ROLE OF ULK1 IN THE BIOLOGY OF GLIOBLASTOMA MULTIFORME N. Martella¹, D. Gargano¹, G. Trotto¹, A. Ioni², M. Calvitto¹, G. Sferra¹, M. Segatto¹, M. Catalano², C. Limatola², J. Dengjel³, S. Di Bartolomeo¹ | ¹Dept. of Biosciences and Territory, University of Molise, Italy; ²Dept. of Physiology and Pharmacology, Sapienza University of Rome, Italy; ³Dept. of Department of Biology, University of Fribourg, Switzerland

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  https://doi.org/10.4081/ejh.2026.4668

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• 51 | DEVELOPMENTAL TOXICITY OF DIBUTYLPFTALATE ALONE AND IN MIXTURE WITH SUB-TERATOGENIC CONCENTRATIONS OF ETHANOL: PRELIMINARY RESULTS ON XENOPUS LAEVIS EMBRYOS (R-FETAX) E. Menegola¹, F. Metruccio², R. Bacchetta¹, M. Battistoni¹, F. Di Renzo¹ | ¹Dept of Environmental Science and Policy Università degli Studi di Milano, Italy; ²ICPS, ASST Fatebenefratelli Sacco, Milan, Italy

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  https://doi.org/10.4081/ejh.2026.4669

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• 52 | EFFECTS OF DIETARY FRUCTOSE ON DUODENAL MUCIN GLYCOSYLATION AND MUCUS PRODUCTION IN MICE FED A HIGH-FAT DIET D. Mentino¹, A. Provera², C. Vecchio², A. Antonioli², A.N. Sheferaw², N. Taldone¹, R. Vitale³, C. Passamonti⁴, S. Fensore⁵, F. Prodam², S. Sutti², M. Mastrodonato^1|6, M. F. Faienza³ | ¹Department of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, Italy; ²Department of Health Sciences, University of Piemonte Orientale, Novara, Italy; ³ Department of Mathematics, University of Luxembourg, Belval Esch-sur-Alzette, Luxembourg; ⁴Department of Socio-Economic, Managerial and Statistical Studies, University of Chieti-Pescara, 3Pediatric Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari Aldo Moro, Italy; ⁶National Research Council of Italy (CNR) - Water Research Institute (IRSA),Taranto, Italy

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  https://doi.org/10.4081/ejh.2026.4670

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• 53 | CYTOTOXIC EFFECTS OF NANOPLASTICS ON THE MALE GONADS OF MYTILUS GALLOPROVINCIALIS Migliaccio Vincenzo¹, Romano Rossana², Luigi Rosati³, Lionetti Lillà¹, Motta Chiara Maria³, Palma Simoniello² | ¹Dept. Chemistry and Biology “Adolfo Zambelli” University of Salerno, Italy; ²Dept. of Science and Technology, University Parthenope, Napoli, Italy; ³Dept. of Biology, University of Naples Federico II, Napoli, Italy

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  https://doi.org/10.4081/ejh.2026.4671

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• 54 | RODLET-LIKE CELLS IN THE YELLOW-LEGGED GULL (LARUS MICHAHELLIS): FIRST EXPLORATORY STUDY OF THE INTESTINAL IMMUNE SYSTEM A. Nunnari¹, A. Miller², G.P. Lombardo¹, F. Grosso³, M. Aragona³, E.R. Lauriano¹ | ¹Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina, Italy; ²Department for the Promotion of Human Sciences and Quality of life, San Raffaele University, Rome, Italy; ³Department of Veterinary Sciences, University of Messina, Italy

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  https://doi.org/10.4081/ejh.2026.4672

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• 55 | A SELF-FOLDING HUMAN NEURAL TUBE MODEL USING 4D SMART SCAFFOLDS C. Dell’Amico¹, I. Chiesa², A. Toffano¹, A. Esposito², P. Mancini², C. Magliaro², A. Louvi³, C. De Maria², M. Onorati¹ | ¹Department of Biology, Unit of Cell, Molecular, and Developmental Biology, University of Pisa, Italy; ²Department of Information Engineering and Research Center Enrico Piaggio, University of Pisa, Italy; ³Departments of Neurosurgery and Neuroscience, Yale School of Medicine, New Haven, USA

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  https://doi.org/10.4081/ejh.2026.4673

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• 56 | THE CARDIAC ENHANCER RNA CHHEAF PRESERVES HEART FUNCTION DURING STRESS ADAPTATION VIA RTN4-DEPENDENT AUTOPHAGY C. Pagiatakis, S. Serio, D. Bonisolo, A. Romanò, G. Bernardini, R. Gornati, R. Papait | Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy

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  https://doi.org/10.4081/ejh.2026.4674

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• 57 | PUNICA GRANATUM-DERIVED EXTRACELLULAR VESICLES EFFECTS ON AN IN VITRO GASTROINTESTINAL BARRIER MODEL OF INTESTINAL INFLAMMATION Mariano Stefania¹, Carata Elisabetta², Moris Destino², Bernardetta Anna Tenuzzo², Panzarini Elisa² | ¹Department of Mathematics and Physics “E. De Giorgi”, University of Salento, Lecce, Italy; ²Department of Biological Sciences and Technologies, University of Salento, Lecce, Italy

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  https://doi.org/10.4081/ejh.2026.4675

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• 58 | AN EX VIVO GRAFTING PLATFORM TO DISSECT TISSUE-DEPENDENT GUIDANCE OF SEROTONERGIC AXONS M. Picchi¹, M. Hingorani², S. Migliarini¹, S. Nazzi¹, G. Gianni¹, N. Barsotti¹, S. Janusonis², M. Pasqualetti¹ | ¹Department of Biology, University of Pisa, Italy; ²Department of Psychological and Brain Sciences, University of California Santa Barbara, USA

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  https://doi.org/10.4081/ejh.2026.4676

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• 59 | ZEBRAFISH EMBRYOS AS A MODEL FOR IN VIVO EVALUATION OF NANOPARTICLE AND VESICLE BASED DELIVERY SYSTEMS A. Piersanti¹, A. Tesoriere¹, F. Sernesi¹, S. Pozzo², Grigoletto³, G. Adamo⁴, A. Bongiovanni⁴, G. Pasut³, F. Mancin², N. Tiso¹, F. Argenton¹ | ¹Department of Biology, University of Padova, Padova, Italy; ²Department of Chemistry, University of Padova, Italy; ³Department of Pharmaceutical Sciences, University of Padova, Italy; ⁴Institute for Research and Biomedical Innovation (IRIB) - National Research Council of Italy (CNR), Palermo, Italy

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  https://doi.org/10.4081/ejh.2026.4677

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• 60 | CELLULAR DYSHOMEOSTASIS AND REDOX IMBALANCE INDUCED BY CANTHARIDIN IN GLIOBLASTOMA MODELS R. Proietti, V. D’Ezio, A. Presaghi, L. Salsedo, A. Sperati, M.A. Bologna, M. Colasanti, T. Persichini | Dept. of Science, Roma Tre University, Rome, Italy

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  https://doi.org/10.4081/ejh.2026.4678

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• 61 | ROTENONE-INDUCED OXIDATIVE STRESS TRIGGERS PEROXISOMAL ALTERATIONS IN BV-2 MICROGLIAL CELLS F. Rendina¹, A. Valenza¹, M. Muzzi², D. Pensabene², A. Fracassi³, M. Segatto², S. Moreno^1|3 | ¹Dept. of Science, University Roma Tre, Rome, Italy. ²Dept. of Biosciences and Territory, University of Molise, Pesche, Italy. ³Dept. of Neurology, UTMB, Galveston, TX, USA

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  https://doi.org/10.4081/ejh.2026.4679

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• 62 | APPLICATION OF AN AI-BASED WORKFLOW FOR THE ASSESSMENT OF TESTICULAR DAMAGE IN DOGS Lorenzo Riccio^1|2, Maria De Falco², Nicola Ambrosio³, Angelo Spada³, Francesca Del Porto², Cristina Marchetti², Orlando Paciello¹, Luigi Rosati² | ¹Dept. of Veterinary Medicine and Animal Productions, University of Naples Federico II, Italy; ²Dept. of Biology, University of Naples Federico II, Italy; ³ASL Napoli 2 Nord, Italy

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  https://doi.org/10.4081/ejh.2026.4680

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• 63 | EVOLUTIONARY STRATEGIES OF CARDIAC GROWTH: THE ICEFISH HEART AS A MODEL TO CONTRAST PATHOLOGICAL CELLULAR MALADAPTATION N. Romano¹, R. Gaetani², M. Gerdol³, C. Bidoli³, M. Mercola4 E. Messina² | ¹Dept. of Life Sciences, Health and Health Professions, Link Campus University, Rome, Italy; ²Dept. of Molecular Medicine, Sapienza University, Rome, Italy; ³Dept. of Life Sciences, University of Trieste, Italy; ⁴Dept. of Medicine and Cardiovascular Institute, Stanford University, Palo Alto, CA, USA

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  https://doi.org/10.4081/ejh.2026.4681

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• 64 | UNDERSTANDING PROPERTIES OF NEURAL STEM CELLS ISOLATED FROM A MONOGENIC MOUSE MODEL OF AUTISM EXPRESSING THE R451C NLGN3 MUTATION F. Salvadori, T. Diamanti, L. Santini, S. D’Angelo, F. Serafini, M. Fidaleo, G. Lupo, A. De Jaco, E. Cacci | Department of Biology and Biotechnology “Charles Darwin”, Sapienza University of Rome, Italy

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  https://doi.org/10.4081/ejh.2026.4682

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• 65 | EFFECTS OF ENVIRONMENTAL TEMPERATURE VARIATION AND BDNF MODULATION ON THE SPATIO-TEMPORAL SHOALING BEHAVIOUR OF ADULT ZEBRAFISH (DANIO RERIO) REVEALED BY TWO- AND THREE-DIMENSIONAL ANALYSIS A.S. Sanchez Garcia¹, F. Frabetti², G. Brighi², G. Tedeschi^3|4, A. Racca⁵, E. Alleva⁵, M. Toni¹ | ¹Dept. of Biology and Biotechnologies “Charles Darwin”, Rome, Italy; ²Dept. of Medical and Surgical Sciences, Bologna, Italy; ³Dept. of Veterinary Medicine and Animal Science, University of Milan, Italy; ⁴CRC “Innovation for Well-Being and Environment”, University of Milan, Italy; ⁵Centre for Behavioural Sciences and Mental Health, Rome, Italy

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  https://doi.org/10.4081/ejh.2026.4683

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• 66 | THE EVOLUTION OF NEURONAL SCALING IN AMNIOTES G. Sansalone¹, S. Castiglione², G. Girardi², P. Dell’Albani¹, P. Raia¹ | ¹Department of Life Sciences, University of Modena and Reggio Emilia, Italy; ²DiSTAR, Università di Napoli Federico II, Naples, Italy

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  https://doi.org/10.4081/ejh.2026.4684

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• 67 | DYNAMICS AND INTRACELLULAR TRAFFICKING OF M2R-DUALSTERIC AGONIST COMPLEX INTO GLIOBLASTOMA CELLS G. Scanavino¹, C. Metelli¹, L. Sileo¹, C. Dallanoce², Matera², AM. Tata¹ | ¹Dept. of Biology and Biotechnology, University of Rome “Sapienza”, Italy; ²Dept. of Pharmaceutical Sciences, University of Milan, Italy

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  https://doi.org/10.4081/ejh.2026.4685

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• 68 | RESILIENCE ASSOCIATED WITH DEFECTS IN VITAMIN B12 METABOLISM: BALANCING BETWEEN HOMEOSTASIS AND DISEASE E. Selita¹, E. Tomaselli², G. Di Matteo³, L. Mannina³, M. Rossi^2|4, D. Passeri^2|4, L. Angeloni^2|4, M. Fidaleo^1|4 | ¹Dept of Biology and Biotechnology, Charles Darwin, University of Rome Sapienza, Italy; ²Dept of Basic and Applied Sciences for Engineering, Sapienza University of Rome, Italy; ³Dept of Chemistry and Technology of Drugs, Sapienza University of Rome, Italy; ⁴Research Centre for Nanotechnology for Engineering of Sapienza (CNIS), Sapienza University of Rome, Italy

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  https://doi.org/10.4081/ejh.2026.4686

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• 69 | ALCL3 TREATMENTS INDUCED MORPHOLOGICAL AND MICROSCOPICAL ALTERATIONS IN PELOPHYLAX LESSONAE EMBRYOS D. Semeraro¹, G. Scillitani¹, D. Mentino¹, M.V. Guglielmi², R. Rossi³, M. Mastrodonato¹ | ¹Dept. Biosciences, Biotechnology and Environment (DBBA), University of Bari Aldo Moro, Italy; ²National Interuniversity Consortium for Marine Sciences (CoNISMa), Rome, Italy; ³Dept. of Pecision and Regenerative Medicine and Ionian Area (DIMEPRE-J), University of Bari Aldo Moro, Italy

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  https://doi.org/10.4081/ejh.2026.4687

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• 70 | IMPACTS OF ANTHROPOGENIC NOISE ON CEPHALOCHORDATES E. Serafini¹, M. Bozzo¹, E. Bosi¹, V. Bazzurro¹, G. Blumer², E. Rodriguéz Quintana³, N. P. Torres Águila³, G. Sabbadin⁴, E. Panarari⁵, S. Norland⁶, M. Pestarino¹, S. Ravera⁷, V. Zaffaroni-Caorsi⁸, I. Guarneri⁹, R. M. Alsina-Pagès¹⁰, I. Nou-Plana¹⁰, G. Zambon⁸, R. Pennati², S. Candiani¹ | ¹DISTAV, University of Genoa, Italy; ²ESP University of Milano, Italy; ³Dep. de Genètica, Microbiologia i Estadística and IRBio, Universitat de Barcelona, Spain; ⁴DiBio, University of Padua, Italy; ⁵SZN, Naples, Italy; ⁶Michael Sars Centre, University of Bergen, Norway; ⁷DIMES, University of Genoa, Italy; ⁸DISAT, University of Milano-Bicocca, Italy; ⁹CNR-ISMAR, Venice, Italy; ¹⁰HER, Universitat Ramon Llull - La Salle, Barcelona, Spain

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  https://doi.org/10.4081/ejh.2026.4688

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• 71 | EFFECT OF DI-N-BUTYL PHTHALATE ON ADIPOGENESIS B. Sgangarella Valvano¹, S. Boccia², A. Mileo³, C. Pivonello⁴, G. Guerra¹, A. De Luca², M. De Falco^5|6 | ¹Dept. of Medicine and Health Sciences “Vincenzo Tiberio”, University of Molise, Campobasso, Italy; ²Dept. of Mental and Physical Health and Preventive Medicine, University of Campania “Luigi Vanvitelli”, Naples, Italy; ³Dept. of Life Sciences, Health and Health Professions, Link Campus University, Rome, Italy; ⁴Dept. of Public Health, University of Naples Federico II, Naples, Italy; ⁵Dept. of Biology, University of Naples Federico II, Naples, Italy; ⁶National Institute of Biostructures and Biosystems (INBB), Rome, Italy

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• 72 | BACULUM ONTOGENY IN WILD VIETNAMESE PRIMATES REVEALED BY MICRO-CT, 3D MORPHOMETRICS, AND INTERNAL MICROARCHITECTURE F. Spani¹, G. Franceschini², M. Carosi², T. Nadler³, M. Colasanti² | ¹Dept. of Science and Bio-Technology, Università Campus Bio-Medico di Roma, Italy; ²Dept. of Sciences, Roma Tre University, Italy; ³Three Monkeys Wildlife Conservancy, Vietnam

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• 73 | PROTECTIVE ROLE FOR OLEOYLETHANOLAMIDE IN THE HUMAN BRAIN: EFFECTS ON THE MODULATION OF NEUROINFLAMMATION AND INSULIN RESISTANCE IN HUMAN ASTROCYTES Lucia Sileo¹, Giulia Scanavino¹, Silvana Gaetani², Ada MariaTata¹ | ¹Dept. of Biology and Biotechnologies "Charles Darwin", University of Rome "Sapienza", Rome, Italy; ²Dept. of Physiology and Pharmacology “Vittorio Erspamer”, University of Rome "Sapienza", Rome, Italy

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• 74 | IMPACT OF IVERMECTIN ON THE GONADS OF THE MARINE MUSSEL MYTILUS GALLOPROVINCIALIS AND REPERCUSSION ON THE EMBRYO DEVELOPMENT M. Terranova^1|2|3, G. La Pusata², N. Caruso^1|2, M. Galati², A. Fazio², T. Cappello², M. Maisano² | ¹Dept. of Earth and Marine Sciences, University of Palermo, Italy; ²Dept. of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Italy; ³National Biodiversity Future Center (NBFC), Palermo, Italy

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  https://doi.org/10.4081/ejh.2026.4692

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• 75 | Β-SITOSTEROL-D-GLUCOSIDE TRIGGERS INTESTINAL INFLAMMATION IN ZEBRAFISH LARVAE POSSIBLY LEADING TO NEURODEGENERATION THROUGH THE GUT-BRAIN AXIS Francesca Terrin¹, Sofia Faggin^2|3, Chiara Consorti⁴, Stefania Marcotti⁵, Paolo Bonaldo⁴, Maria Cecilia Giron², Nicoletta Plotegher¹, Luisa Dalla Valle¹ | ¹Department of Biology, University of Padova, Italy; ²Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Italy; ³Institute of Digestive Health Research (IRSD), Toulouse University, France; ⁴Department of Molecular Medicine, University of Padova, Italy; ⁵Randall Centre for Cell and Molecular Biophysics, King's College London, London; UK

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  https://doi.org/10.4081/ejh.2026.4693

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• 76 | DECODING THES PATHOGENESIS: HOW TTC37 SHAPES GUT HOMEOSTASIS AND PERISTALSIS A. Tesoriere¹, F. Sernesi¹, A. Piersanti¹, M. Gasparotto³, L. Dalla Valle¹, M. Cananzi², F. Argenton¹ | ¹University of Padova, Italy;²University Hospital of Padova, Italy; ³Central Institute of Mental Health, Mannheim, Germany

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  https://doi.org/10.4081/ejh.2026.4694

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• 77 | TARGETING P75NTR CORRECTS OXIDATIVE AND INFLAMMATORY IMBALANCES IN A CELLULAR MODEL OF RETT SYNDROME M. Varone, M. Colardo, N. Martella, D. Pensabene, E. Bisesto, M. Segatto | Dept of Biosciences and Territory, University of Molise, Pesche, Italy

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