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miR-129-5p regulates HMGB1/RAGE axis to inhibit pyroptosis and ameliorate cervical epithelial cell deterioration

Huafang Wang, Dilidaer Sidike, Pan Liu, Longge Suo, Huerxidan Niyazi

23-09-2025

https://doi.org/10.4081/ejh.2025.4238

441

PDF: 359

HTML: 13
Pre-treatment with galectin-1 attenuates lipopolysaccharide-induced myocarditis by regulating the Nrf2 pathway

Liying Shen, Kongjie Lu, Zhenfeng Chen, Yingwei Zhu, Cong Zhang, Li Zhang

07-12-2023

https://doi.org/10.4081/ejh.2023.3816

1213

PDF: 702

HTML: 37
Porphyromonas gingivalis lipopolysaccharide stimulation in human periodontal ligament stem cells: role of epigenetic modifications to the inflammation

Francesca Diomede, Soundara Rajan Thangavelu, Ilaria Merciaro, Monica D'Orazio, Placido Bramanti, Emanuela Mazzon, Oriana Trubiani

25-08-2017

https://doi.org/10.4081/ejh.2017.2826

3101

PDF: 1309

HTML: 142
Dexmedetomidine attenuates neuroinflammation and microglia activation in LPS-stimulated BV2 microglia cells through targeting circ-Shank3/miR-140-3p/TLR4 axis

Guangbao He, Yibo He, Hongwei Ni, Kai Wang, Yijun Zhu, Yang Bao

26-07-2023

https://doi.org/10.4081/ejh.2023.3766

2065

PDF: 1293

HTML: 21
MyD88/ERK/NFkB pathways and pro-inflammatory cytokines release in periodontal ligament stem cells stimulated by Porphyromonas gingivalis

Francesca Diomede, Maria Zingariello, Marcos F.X.B. Cavalcanti, Ilaria Merciaro, Jacopo Pizzicannella, Natalia de Isla, Sergio Caputi, Patrizia Ballerini, Oriana Trubiani

24-05-2017

https://doi.org/10.4081/ejh.2017.2791

3310

PDF: 1383

HTML: 153
Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function

Zhijiang Chen, Huili Wang, Bin Hu, Xinxin Chen, Meiyu Zheng, Lili Liang, Juanjuan Lyu, Qiyi Zeng

21-06-2022

https://doi.org/10.4081/ejh.2022.3412

2516

PDF: 1426

HTML: 33
Decreased VEGFA alleviates the symptoms of LPS-induced sepsis in a mouse model by inhibiting glycolysis and thereby regulating the polarization of macrophages

Jun Lin, Liping Jiang, Kun Guo, Ning Feng

22-12-2022

https://doi.org/10.4081/ejh.2023.3528

2020

PDF: 1235

Supplementary: 135

HTML: 39
Adipose-derived stem cells promote the recovery of intestinal barrier function by inhibiting the p38 MAPK signaling pathway

Mei Yang, Wangbin Xu, Chaofu Yue, Rong Li, Xian Huang, Yongjun Yan, Qinyong Yan, Shisheng Liu, Yuan Liu, Qiaolin Li

21-01-2025

https://doi.org/10.4081/ejh.2025.4158

1843

PDF: 592

Supplementary Figure: 89

HTML: 61
Pretreatment with interleukin-15 attenuates inflammation and apoptosis by inhibiting NF-κB signaling in sepsis-induced myocardial dysfunction

Chaojie He, Yi Yu, Feifan Wang, Wudi Li, Hui Ni, Meixiang Xiang

29-04-2024

https://doi.org/10.4081/ejh.2024.4019

1917

PDF: 713

HTML: 28
Mucin1 relieves acute lung injury by inhibiting inflammation and oxidative stress

Chunlin Ye, Bin Xu, Jie Yang, Yunkun Liu, Zhikai Zeng, Lingchun Xia, Quanjin Li, Guowen Zou

02-12-2021

https://doi.org/10.4081/ejh.2021.3331

2599

PDF: 1487

HTML: 40
Cryptotanshinone alleviates DSS-induced colitis in mouse by regulating the balance of Treg/Th17 cells and M1 macrophage activation

Lin Liu, Wei Huang, Yu Wu, Guanlong Ye, Jing Zhang, Tong Shen, Changjuan Ouyang

19-02-2026

https://doi.org/10.4081/ejh.2026.4436

588

PDF: 333

HTML: 13
Different iron-handling in inflamed small and large cholangiocytes and in small and large-duct type intrahepatic cholangiocarcinoma

Romina Mancinelli, Antimo Cutone, Luigi Rosa, Maria Stefania Lepanto, Paolo Onori, Luigi Pannarale, Antonio Franchitto, Eugenio Gaudio, Piera Valenti

19-10-2020

https://doi.org/10.4081/ejh.2020.3156

1728

PDF: 769

HTML: 24
Effects of piperlonguminine on lung injury in severe acute pancreatitis via the TLR4/NF-κB pathway

Qian Hu, Ran Tao, Xiaoyun Hu, Haibo Wu, Jianjun Xu

20-03-2023

https://doi.org/10.4081/ejh.2023.3639

1257

PDF: 736

HTML: 26
Erratum - Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function

Zhijiang Chen, Huili Wang, Bin Hu, Xinxin Chen, Meiyu Zheng, Lili Liang, Juanjuan Lyu, Qiyi Zeng

20-06-2023

https://doi.org/10.4081/ejh.2023.3794

790

PDF: 491

HTML: 21
Placental mesenchymal stem cell exosomes drive macrophage M2 polarization via the miR-146a-5p/TRAF6 axis to ameliorate preeclampsia

Xiaoli Liu, Ruiyue Li, Junjie Sun, Yuanpei Yang, Lina Hu

17-11-2025

https://doi.org/10.4081/ejh.2025.4426

936

PDF: 500

HTML: 19
P52 | MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL EVALUATION OF THE ANTI-INFLAMMATORY AND ANTIOXIDANT PROPERTIES OF HEMP EXTRACTS ON THE LIVER OF RATS INVOLVED IN INFLAMMATION CAUSED BY LPS A. Miller¹, M. Kotanska², M. Bednarski², G.P. Lombardo³, V. Natale³, G. Pirracchio³, L. Spiccia³, S. Pergolizzi³, G. Rizzo⁴, E.R. Lauriano³ | ¹Department of Veterinary Sciences, University of Messina, Messina, Italy; ²Department of Pharmacological Screening, Jagiellonian University Medical College, Kraków, Poland: ³Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina, Italy; ⁴Department of Clinical and Experimental Medicine, University of Messina, Italy

21-08-2025

https://doi.org/10.4081/ejh.2025.4374

288
P21 | INVOLVEMENT OF TELOCYTES IN CARDIAC INFLAMMATION CAUSED BY LPS IN MICE AND THE POTENTIAL ANTI-INFLAMMATORY ROLE OF CANNABIS SATIVA L. A. Miller¹, G.P. Lombardo², A. Nunnari², G. Pirracchio², M. Kotańska³, C. Condurso⁴, E.R. Lauriano², S. Pergolizzi² | ¹Dept. for the Promotion of Human Sciences and Quality of life, San Raffaele University, Rome, Italy; ²Dept. of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Italy; ³Dept. of Pharmacological Screening, Jagiellonian University Medical; College, Kraków, Poland; ⁴Dept of Veterinary Sciences, University of Messina, Italy

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

https://doi.org/10.4081/ejh.2026.4717

60

PDF: 5
Histopathological and immunofluorescent characterization of post-sepsis immune dysregulation in a clinically relevant mouse model

Haoran Tang, Chen Liao, Ning Tang, Hui Li, Yi Liu, Lingling Wang, Zongfang Ren

12-02-2026

https://doi.org/10.4081/ejh.2026.4435

540

PDF: 354

HTML: 14
Propofol alleviates M1 polarization and neuroinflammation of microglia in a subarachnoid hemorrhage model in vitro, by targeting the miR-140-5p/TREM-1/NF-κB signaling axis

Lan Wang, Zhenyu Fan, Haijin Wang, Shougui Xiang

17-09-2024

https://doi.org/10.4081/ejh.2024.4034

1214

PDF: 632

HTML: 13
Knockdown of miR-411-3p induces M2 macrophage polarization and promotes colorectal cancer progression by regulation of MMP7

Tianliang Bai, Ping Li, Yabin Liu, Bindan Cai, Gang Li, Wenbin Wang, Rui Yan, Xiangkui Zheng, Shangkun Du

05-05-2025

https://doi.org/10.4081/ejh.2025.4178

942

PDF: 401

Supplementary: 52

HTML: 50
Developmental characteristics of cutaneous telocytes in late embryos of the silky fowl

Hao Li, Junliang Chen, Wenjun You, Yizhen Xu, Yaqiong Ye, Haiquan Zhao, Junxing Li, Hui Zhang

15-10-2024

https://doi.org/10.4081/ejh.2024.4089

1735

PDF: 389

HTML: 14
ECRG4 expression in normal rat tissues: expression study and literature review

A. Porzionato, M. Rucinski, V. Macchi, G. Sarasin, L.K. Malendowicz, R. De Caro

18-05-2015

https://doi.org/10.4081/ejh.2015.2458

3049

PDF: 1173

Supplementary: 388

HTML: 1015
DNMT1 regulates IL-6- and TGF-β1-induced epithelial mesenchymal transition in prostate epithelial cells

Hui Xu, Yanbo Chen, Qi Chen, Huan Xu, Yanxia Wang, Jiao Yu, Juan Zhou, Zhong Wang, Bing Xu

03-05-2017

https://doi.org/10.4081/ejh.2017.2775

2708

PDF: 1032

HTML: 184
An emerging potential therapeutic target for osteoporosis: LncRNA H19/miR-29a-3p axis

Ziqi Li, Zhinan Hong, Yuesheng Zheng, Yongwei Dong, Wei He, Yingjia Yuan, Junbiao Guo

06-11-2020

https://doi.org/10.4081/ejh.2020.3155

1591

PDF: 740

HTML: 13
Tumor cells-derived exosomal PD-L1 promotes the growth and invasion of lung cancer cells in vitro via mediating macrophages M2 polarization

Xiangjun Lu, Jian Shen, Siyuan Huang, Dongdong Liu, Haitao Wang

01-08-2023

https://doi.org/10.4081/ejh.2023.3784

2043

PDF: 884

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Deubiquitinase USP14 is upregulated in Crohn's disease and inhibits the NOD2 pathway mediated inflammatory response in vitro

Mengling Li, Yan Zhao, Jiayi Zhang, Wang Jiang, Siyuan Peng, Jinyue Hu, Yueming Shen

09-09-2024

https://doi.org/10.4081/ejh.2024.4101

1308

PDF: 442

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Altered alkaline phosphatase activity in obese Zucker rats liver respect to lean Zucker and Wistar rats discussed in terms of all putative roles ascribed to the enzyme

V. Bertone, E. Tarantola, A. Ferrigno, E. Gringeri, S. Barni, M. Vairetti, I. Freitas

e5

08-02-2011

https://doi.org/10.4081/ejh.2011.e5

1479

PDF: 799

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P65 | (YS) INVESTIGATING THE EFFECTS OF THE SECRETOME FROM HUMAN AMNIOTIC MESENCHYMAL STROMAL CELLS ON INFLAMMASOME ACTIVATION M. Rossi¹, M. Magatti², P. Romele², E. Vertua², E. Giuzzi², S. Farigu², L. Marelli², B. Rapuzzi², S. De Munari², A. Silini², O. Parolini³ | ¹Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, and Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy; ²Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy; ³Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy & Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy

21-08-2025

https://doi.org/10.4081/ejh.2025.4390

266
Characterization of PD-1/PD-L1 immune checkpoint expression in soft tissue sarcomas

Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Masao Akagi

02-07-2021

https://doi.org/10.4081/ejh.2021.3203

3115

PDF: 944

HTML: 37
Quantitative, structural and molecular changes in neuroglia of aging mammals: A review

Ennio Pannese

23-06-2021

https://doi.org/10.4081/ejh.2021.3249

1726

PDF: 858

HTML: 18
Enhancement of immunohistochemical detection of Salmonella in tissues of experimentally infected pigs

J. Rieger, P. Janczyk, H. HÃ¼nigen, J. Plendl

09-07-2015

https://doi.org/10.4081/ejh.2015.2516

2543

PDF: 965

HTML: 1034
Tumor cell-derived exosomal lncRNA LOC441178 inhibits the tumorigenesis of esophageal carcinoma through suppressing macrophage M2 polarization

Jiangmu Chen, Zongchi Chen, Weitao Hu, Daxing Cai

14-10-2022

https://doi.org/10.4081/ejh.2022.3510

1314

PDF: 681

HTML: 38
Pretreatment with geniposide mitigates myocardial ischemia/reperfusion injury by modulating inflammatory response through TLR4/NF-κB pathway

Yanmei Yao, Leqing Lin, Wenxue Tang, Yueliang Shen, Fayu Chen, Ning Li, Baiyong Wang

08-09-2023

https://doi.org/10.4081/ejh.2023.3742

1177

PDF: 484

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From the intestinal mucosal barrier to the enteric neuromuscular compartment: an integrated overview on the morphological changes in Parkinson’s disease

Carolina Pellegrini, Vanessa D'Antongiovanni, Chiara Ippolito, Cristina Segnani, Luca Antonioli, Matteo Fornai, Nunzia Bernardini

22-11-2021

https://doi.org/10.4081/ejh.2021.3278

1543

PDF: 854

HTML: 42
Contribution of intestinal smooth muscle to Crohn's disease fibrogenesis

C. Severi, R. Sferra, A. Scirocco, A. Vetuschi, N. Pallotta, A. Pronio, R. Caronna, G. Di Rocco, E. Gaudio, E. Corazziari, P. Onori

17-12-2014

https://doi.org/10.4081/ejh.2014.2457

2961

PDF: 1155

HTML: 436
Ghrelin reduces cerebral ischemic injury in rats by reducing M1 microglia/macrophages

Rong Tian, Gengsheng Mao

12-01-2022

https://doi.org/10.4081/ejh.2022.3350

1836

PDF: 910

HTML: 41
73 | PROTECTIVE ROLE FOR OLEOYLETHANOLAMIDE IN THE HUMAN BRAIN: EFFECTS ON THE MODULATION OF NEUROINFLAMMATION AND INSULIN RESISTANCE IN HUMAN ASTROCYTES Lucia Sileo¹, Giulia Scanavino¹, Silvana Gaetani², Ada MariaTata¹ | ¹Dept. of Biology and Biotechnologies "Charles Darwin", University of Rome "Sapienza", Rome, Italy; ²Dept. of Physiology and Pharmacology “Vittorio Erspamer”, University of Rome "Sapienza", Rome, Italy

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

https://doi.org/10.4081/ejh.2026.4691

64

PDF: 10
Upregulation of cardiac NO/NOS system during short-term hypoxia and the subsequent reoxygenation period

A. Rus, M.L. Del Moral, F. Molina, M.A. Peinado

e17

17-05-2011

https://doi.org/10.4081/ejh.2011.e17

1202

PDF: 537

HTML: 1409
The possible alleviating effect of garlic supplement on the neural retina in a rat model of hypercholesterolemia: a histological and immunohistochemical study

Eetmad A. Arafat, Eman M.I. Youssef, Hanaa A. Khalaf

16-12-2021

https://doi.org/10.4081/ejh.2021.3322

1311

PDF: 563

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Cannabinoid CB2 receptors are involved in the protection of RAW264.7 macrophages against the oxidative stress: an in vitro study

Sabrina Giacoppo, Agnese Gugliandolo, Oriana Trubiani, Federica Pollastro, Gianpaolo Grassi, Placido Bramanti, Emanuela Mazzon

23-01-2017

https://doi.org/10.4081/ejh.2017.2749

6046

PDF: 1365

HTML: 402
Visnagin ameliorates myocardial ischemia/reperfusion injury through the promotion of autophagy and the inhibition of apoptosis

Hai-rong Fu, Xiao-shan Li, Yong-hui Zhang, Bin-bin Feng, Lian-hong Pan

07-09-2020

https://doi.org/10.4081/ejh.2020.3131

1292

PDF: 942

HTML: 15
Identification of 5-hydroxytryptamine-producing cells by detection of fluorescence in paraffin-embedded tissue sections

Y. Kaneko, N. Onda, Y. Watanabe, M. Shibutani

29-09-2016

https://doi.org/10.4081/ejh.2016.2684

2239

PDF: 835

HTML: 311
P10 | BIOLOGICAL ACTIVITIES OF CITRUS LIMON-, VITIS VINIFERA- AND ACTINIDIA DELICIOSA-DERIVED EXTRACELLULAR VESICLES ON HUMAN CACO-2 CELLS M. Destino, E. Carata, B.A. Tenuzzo, E. Panzarini | Department of Biological and Environmental Sciences and Technologies (Di.S.Te.B.A.), University of Salento, Lecce, Italy

GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA

22-06-2026

https://doi.org/10.4081/ejh.2026.4706

60

PDF: 5
Expressions of TLR4, MyD88, IRAK4 and NF-κΒ in the oviduct of Chinese brown frog (Rana dybowskii)

Yue Zhang, Ao Zhang, Yue Zhao, Xiaohang Feng, Yuyao Sheng, Haolin Zhang, Qiang Weng, Meiyu Xu

25-09-2019

https://doi.org/10.4081/ejh.2019.3050

1108

PDF: 555

HTML: 19
Toll-like receptor 4 expression in the epithelium of inflammatory periapical lesions. An immunohistochemical study

R. Leonardi, R.E. Perrotta, C. Loreto, G. Musumeci, S. Crimi, J.N. dos Santos, M.C. Rusu, P. Bufo, E. Barbato, G. Pannone

26-10-2015

https://doi.org/10.4081/ejh.2015.2547

1877

PDF: 1064

HTML: 358
Bovine pericardium membrane, gingival stem cells, and ascorbic acid: a novel team in regenerative medicine

Jacopo Pizzicannella, Guya D. Marconi, Sante D. Pierdomenico, Marcos F.X.B. Cavalcanti, Francesca Diomede, Oriana Trubiani

25-09-2019

https://doi.org/10.4081/ejh.2019.3064

1713

PDF: 841

HTML: 24
Expression and role of cocaine-amphetamine regulated transcript (CART) in the proliferation of biliary epithelium

Arianna Casini, Giorgio Vivacqua, Rosa Vaccaro, Anastasia Renzi, Stefano Leone, Luigi Pannarale, Antonio Franchitto, Paolo Onori, Romina Mancinelli, Eugenio Gaudio

19-10-2023

https://doi.org/10.4081/ejh.2023.3846

1750

PDF: 660

HTML: 33

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