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• Senescence-associated ß-galactosidase staining over the lifespan differs in a short- and a long-lived fish species

  Simon Schöfer, Sylvia Laffer, Stefanie Kirchberger, Michael Kothmayer, Renate Löhnert, Elmar E. Ebner, Klara Weipoltshammer, Martin Distel, Oliver Pusch, Christian Schöfer

  29-02-2024

  https://doi.org/10.4081/ejh.2024.3977

  1887

  PDF: 992

  Supplementary: 90

  HTML: 75
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  Premature senescence in primary muscle cultures of myotonic dystrophy type 2 is not associated with p16 induction

  L.V. Renna, R. Cardani, A. Botta, G. Rossi, B. Fossati, E. Costa, G. Meola

  22-10-2014

  https://doi.org/10.4081/ejh.2014.2444

  2297

  PDF: 1003

  HTML: 476
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  Ferroptosis resistance cooperates with cellular senescence in the overt stage of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

  Antonella Vetuschi, Alfredo Cappariello, Paolo Onori, Eugenio Gaudio, Giovanni Latella, Simona Pompili, Roberta Sferra

  21-06-2022

  https://doi.org/10.4081/ejh.2022.3391

  3068

  PDF: 1795

  HTML: 42
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  Nuclear damages and oxidative stress: new perspectives for laminopathies

  G. Lattanzi, S. Marmiroli, A. Facchini, N.M. Maraldi

  e45

  18-10-2012

  https://doi.org/10.4081/ejh.2012.e45

  1901

  PDF: 838

  HTML: 198
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  Lectin-like, oxidized low-density lipoprotein receptor-1-deficient mice show resistance to age-related knee osteoarthritis

  Kazuhiko Hashimoto, Yutaka Oda, Fumihisa Nakamura, Ryosuke Kakinoki, Masao Akagi

  14-02-2017

  https://doi.org/10.4081/ejh.2017.2762

  2845

  PDF: 890

  HTML: 238
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  Autophagic processes increase during senescence in cultured sheep neurons and astrocytes

  Vittorio Farina, Gianluca Lepore, Francesca Biagi, Marcella Carcupino, Marco Zedda

  03-04-2018

  https://doi.org/10.4081/ejh.2018.2891

  2264

  PDF: 624

  HTML: 20
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  Autophagic degradation of farnesylated prelamin A as a therapeutic approach to lamin-linked progeria

  V. Cenni, C. Capanni, M. Columbaro, M. Ortolani, M.R. D'Apice, G. Novelli, M. Fini, S. Marmiroli, E. Scarano, N.M. Maraldi, S. Squarzoni, S. Prencipe, G. Lattanzi

  e36

  19-10-2011

  https://doi.org/10.4081/ejh.2011.e36

  2540

  PDF: 1000
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  Cultured myoblasts from patients affected by myotonic dystrophy type 2 exhibit senescence-related features: ultrastructural evidence

  M. Malatesta, M. Giagnacovo, L.V. Renna, R. Cardani, G. Meola, C. Pellicciari

  e26

  21-09-2011

  https://doi.org/10.4081/ejh.2011.e26

  1980

  PDF: 710
• 

  ECRG4 expression in normal rat tissues: expression study and literature review

  A. Porzionato, M. Rucinski, V. Macchi, G. Sarasin, L.K. Malendowicz, R. De Caro

  18-05-2015

  https://doi.org/10.4081/ejh.2015.2458

  2777

  PDF: 1117

  Supplementary: 357

  HTML: 1010
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  Skeletal muscle features in myotonic dystrophy and sarcopenia: do similar nuclear mechanisms lead to skeletal muscle wasting?

  M. Malatesta

  e36

  10-08-2012

  https://doi.org/10.4081/ejh.2012.e36

  1573

  PDF: 790
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  The hematopoietic stem cells supportive megakaryocytes as shapers of the bone marrow niche

  Francesca Arciprete, Viola Velardi, Paola Verachi, Claudio Carta, Antonio Di Virgilio, Vincenzo Roberti, Giorgio Vivacqua, Rosalba Rana, Maria Zingariello

  16-12-2025

  https://doi.org/10.4081/ejh.2025.4424

  405

  PDF: 187

  HTML: 4
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  Immunohistochemical detection of putative pathogenetic factors in adhesions of infants: a pilot study

  Arvis Pauliņš, Anna Junga, Māra Pilmane

  10-02-2026

  https://doi.org/10.4081/ejh.2026.4438

  115

  PDF: 87

  HTML: 0
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  Immunofluorescent localization of ubiquitin and proteasomes in nucleolar vacuoles of soybean root meristematic cells

  D. Stępiński

  e13

  30-05-2012

  https://doi.org/10.4081/ejh.2012.13

  1043

  PDF: 424

  HTML: 1739
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  Overexpression of hsa_circ_0001861 inhibits pulmonary fibrosis through targeting miR-296-5p/BCL-2 binding component 3 axis

  Tao Wu, Shikui Wu, Hailu Jiao, Jun Feng, Xiang Zeng

  02-10-2023

  https://doi.org/10.4081/ejh.2023.3839

  1219

  PDF: 700

  HTML: 29

• p53 and telomerase control rat myocardial tissue response to hypoxia and ageing

  A. Cataldi, S. Zara, M. Rapino, M. Zingariello, V. di Giacomo, A. Antonucci

  e25

  09-12-2009

  https://doi.org/10.4081/ejh.2009.e25

  1246

  PDF: 708
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  LOX-1 deficient mice show resistance to zymosan-induced arthritis

  Kazuhiko Hashimoto, Yutaka Oda, Koichi Nakagawa, Terumasa Ikeda, Kazuhiro Ohtani, Masao Akagi

  22-01-2018

  https://doi.org/10.4081/ejh.2018.2847

  1882

  PDF: 822

  HTML: 70
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  Stem cells and aging - methods and protocols

  Carlo Alberto Redi

  br14

  01-10-2013

  https://doi.org/10.4081/ejh.2013.br14

  2126

  PDF: 408
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  The expression of Sirtuins 1 and 4 in peripheral blood leukocytes from patients with type 2 diabetes

  R. Song, W. Xu, Y. Chen, Z. Li, Y. Zeng, Y. Fu

  e10

  21-03-2011

  https://doi.org/10.4081/ejh.2011.e10

  1886

  PDF: 606

  HTML: 912
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  Impact of Histochemistry on biomedical research: looking through the articles published in a long-established histochemical journal

  C. Pellicciari

  30-12-2014

  https://doi.org/10.4081/ejh.2014.2474

  2140

  PDF: 645

  HTML: 806
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  Is there still room for novelty, in histochemical papers?

  Carlo Pellicciari

  16-12-2016

  https://doi.org/10.4081/ejh.2016.2758

  2607

  PDF: 678

  HTML: 278
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  Expression of Ser729 phosphorylated PKCepsilon in experimental crescentic glomerulonephritis: an immunohistochemical study

  V.N. Karavana, H. Gakiopoulou, E.A. Lianos

  15-04-2014

  https://doi.org/10.4081/ejh.2014.2308

  2089

  PDF: 841

  HTML: 642
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  Aortic dissection is associated with reduced polycystin-1 expression, an abnormality that leads to increased ERK phosphorylation in vascular smooth muscle cells

  J. Feng, S. Ge, L. Zhang, H. Che, C. Liang

  16-12-2016

  https://doi.org/10.4081/ejh.2016.2711

  2506

  PDF: 942

  HTML: 297

• THE CHEMISTRY OF NUTRACEUTICALS: DRIVING HEALTH INNOVATIONS AND SHAPING NEW PARADIGMS M. Micucci | Department of Biomolecular Sciences, Urbino University “Carlo Bo”, Urbino, Italy

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4317

  181
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  The earthworm Dendrobaena veneta (Annelida): A new experimental-organism for photobiomodulation and wound healing

  Andrea Amaroli, Sara Ferrando, Marina Pozzolini, Lorenzo Gallus, Steven Parker, Stefano Benedicenti

  09-02-2018

  https://doi.org/10.4081/ejh.2018.2867

  2011

  PDF: 884

  HTML: 54
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  Histochemistry as an irreplaceable approach for investigating functional cytology and histology

  C. Pellicciari

  e41

  19-12-2013

  https://doi.org/10.4081/ejh.2013.e41

  3263

  PDF: 802

  HTML: 407
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  Therapeutic effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles on ovarian functions through the PI3K/Akt cascade in mice with premature ovarian failure

  Nan Li, Xue Fan, Lihong Liu, Yanbing Liu

  27-07-2023

  https://doi.org/10.4081/ejh.2023.3506

  1430

  PDF: 921

  HTML: 16

• The histochemical profile of the rat extensor digitorum longus muscle differentiates after birth and dedifferentiates in senescence

  M Lehnert, H Laurer, B Maier, J Frank, I Marzi, W-I Steudel, A Mautes

  111-118

  10-08-2009

  https://doi.org/10.4081/1132

  527

  PDF: 426
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  Histochemistry in biology and medicine: a message from the citing journals

  Carlo Pellicciari

  23-12-2015

  https://doi.org/10.4081/ejh.2015.2610

  2981

  PDF: 833

  HTML: 889

• P13 | MORPHO-FUNCTIONAL DIFFERENCES IN THE GUT OF AGED MICE WITH THE POSSIBLE EFFECTS OF ANTI-INFLAMMATORY TREATMENTS A. Casini¹, S. Leone¹, R. Mancinelli¹, R. Vaccaro¹, M. Catalano², G. D’Alessandro², A. Rinaldi², A. Reccagni², G. Vivacqua³, A. Franchitto⁴, P. Onori¹, C. Limatola², E. Gaudio¹ | ¹Department of Anatomical, Histological, Forensic Medicine and Orthopaedics Sciences, Sapienza University of Rome, Italy; ²Department of Physiology and Pharmacology, Sapienza University of Rome, Italy; ³Department of Medicine and Surgery, University Campus BioMedico of Rome, Italy; ⁴Department of Movement, Human and Health Sciences, Division of Health Sciences, University of Rome «Foro Italico», Rome,Italy

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4333

  128
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  The Qi-Bang-Yi-Shen formula ameliorates renal dysfunction and fibrosis in rats with diabetic kidney disease via regulating PI3K/AKT, ERK and PPARγ signaling pathways

  Zhi Wang, Guihua Jian, Teng Chen, Yiping Chen, Junhui Li, Niansong Wang

  01-03-2023

  https://doi.org/10.4081/ejh.2023.3648

  2401

  PDF: 940

  HTML: 39
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  Tibialis anterior muscle needle biopsy and sensitive biomolecular methods: a useful tool in myotonic dystrophy type 1

  S. Iachettini, R. Valaperta, A. Marchesi, A. Perfetti, G. Cuomo, B. Fossati, L. Vaienti, E. Costa, G. Meola, R. Cardani

  26-10-2015

  https://doi.org/10.4081/ejh.2015.2562

  1865

  PDF: 882

  HTML: 389
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  Forever particles: histochemistry in the plasticene age

  Beatrice Camia, Andrea Casasco, Manuela Monti

  01-08-2025

  https://doi.org/10.4081/ejh.2025.4226

  667

  PDF: 346

  HTML: 24
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  Luminescence and fluorescence of essential oils. Fluorescence imaging in vivo of wild chamomile oil

  F. Boschi, M. Fontanella, L. Calderan, A. Sbarbati

  e18

  16-06-2011

  https://doi.org/10.4081/ejh.2011.e18

  1119

  PDF: 914

  HTML: 1453
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  Protective effect of different antioxidant agents in UVB-irradiated keratinocytes

  Sara Salucci, Sabrina Burattini, Francesca Buontempo, Alberto Maria Martelli, Elisabetta Falcieri, Michela Battistelli

  18-09-2017

  https://doi.org/10.4081/ejh.2017.2784

  2284

  PDF: 956

  HTML: 173
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  Immunohistochemical study of doublecortin and nucleostemin in canine brain

  E. De Nevi, P. Marco-Salazar, D. Fondevila, E. Blasco, L. Pérez, M. Pumarola

  e9

  20-03-2013

  https://doi.org/10.4081/ejh.2013.e9

  2333

  PDF: 652

  HTML: 277
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  Tanshinone IIA attenuates hepatic stellate cell activation, oxidative stress, and liver fibrosis by inhibiting YAP signaling

  Dan Wang, Qingquan Tan, Qing Zheng, Yanling Ma, Li Feng

  17-06-2025

  https://doi.org/10.4081/ejh.2025.4218

  736

  PDF: 347

  HTML: 18
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  The possible prognostic role of histone deacetylase and transforming growth factor β/Smad signaling in high grade gliomas treated by radio-chemotherapy: a preliminary immunohistochemical study

  Roberta Sferra, Simona Pompili, Claudio Festuccia, Francesco Marampon, Giovanni L. Gravina, Luca Ventura, Ernesto Di Cesare, Sara Cicchinelli, Eugenio Gaudio, Antonella Vetuschi

  16-05-2017

  https://doi.org/10.4081/ejh.2017.2732

  2529

  PDF: 947

  HTML: 149
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  Quantitative, structural and molecular changes in neuroglia of aging mammals: A review

  Ennio Pannese

  23-06-2021

  https://doi.org/10.4081/ejh.2021.3249

  1518

  PDF: 787

  HTML: 14
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  Histochemistry through the years, browsing a long-established journal: novelties in traditional subjects

  C. Pellicciari

  e51

  16-12-2010

  https://doi.org/10.4081/ejh.2010.e51

  1389

  PDF: 690

  HTML: 3869

• GLIAL INFLAMMASOME ACTIVATION AND BLOOD-BRAIN BARRIER BREAKDOWN IN AGE-RELATED NEURODEGENERATION Errede M¹, Girolamo F¹, d’Amati A^1,2, de Giorgis M¹, Lorusso L¹, Pierucci C³, Bernardini N³, Pellegrini C³, Virgintino D¹ and Annese T² | ¹University of Bari, Department of Translational Biomedicine and Neuroscience – Human Anatomy and Histology Unit, Bari, Italy; ²Libera Università del Mediterraneo (LUM) Giuseppe Degennaro University, Department of Medicine and Surgery, Bari, Italy; ³University of Pisa, Department of Clinical and Experimental Medicine - Unit of Histology and Medical Embryology, Pisa, Italy

  12-12-2025

  https://doi.org/10.4081/ejh.2025.4460

  230
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  DNA damage and repair in differentiation of stem cells and cells of connective cell lineages: A trigger or a complication?

  Nikolajs Sjakste, Una Riekstiņa

  03-05-2021

  https://doi.org/10.4081/ejh.2021.3236

  2750

  PDF: 1279

  HTML: 78
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  Expression and role of cocaine-amphetamine regulated transcript (CART) in the proliferation of biliary epithelium

  Arianna Casini, Giorgio Vivacqua, Rosa Vaccaro, Anastasia Renzi, Stefano Leone, Luigi Pannarale, Antonio Franchitto, Paolo Onori, Romina Mancinelli, Eugenio Gaudio

  19-10-2023

  https://doi.org/10.4081/ejh.2023.3846

  1586

  PDF: 594

  HTML: 24
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  Structural and functional alterations of the cell nucleus in skeletal muscle wasting: the evidence in situ

  M. Malatesta, G. Meola

  e44

  19-10-2010

  https://doi.org/10.4081/ejh.2010.e44

  1425

  PDF: 566

  HTML: 591