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IMMUNOLOGICAL MECHANISMS IN REGENERATIVE MEDICINE: A LESSON FROM THE HUMAN PLACENTA O. Parolini1,2 | 1Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy; 2Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy
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Long noncoding RNA H19 accelerates tenogenic differentiation by modulating miR-140-5p/VEGFA signaling
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P02 | THE C-C CHEMOKINE-RECEPTOR 2 (CCR2)/CCL2 AXIS PARTICIPATE IN PLATELET FUNCTION IN MYELOFIBROSIS F. Arciprete1, V. Velardi1, G. Pozzi2, C. Carubbi3, S. Cortellazzi3, A.M. Vannucchi4, M. Vitale5, R.A. Rana1, G. Vivacqua1, E. Masselli3, M. Zingariello1 | 1Unit of Microscopic and Ultrastructural Anatomy, University Campus Bio-Medico, Rome, Italy; 2Anatomy Unit, Department of Medicine and Surgery (DiMeC), University of Parma, Parma, Italy; 3Anatomy Unit, Department of Medicine and Surgery (DiMeC), University of Parma, Parma, Italy; 4Center Research and Innovation of Myeloproliferative Neoplasm, University Hospital Careggi, University of Florence, Florence, Italy; 5San Raffaele University, Milano, Italy
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P78 | THE ROLE OF EXTRACELLULAR VESICLES DERIVED FROM MESENCHYMAL STROMAL CELLS IN MYOFIBER REGENERATION A. Longhin1, V. Gatta2, G. Teti2, C. Sassoli3, F. Chellini3, A. Tani3, M. Parigi3, R. Garella3, F. Palmieri3, R. Squecco3, M. Mattioli Belmonte4, C. Licini4, A. La Contana4, S. Zecchi Orlandini3, M. Falconi1 | 1Dep. Medical and Surgical Sciences, University of Bologna, Bologna, Italy; 2Dep. Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy; 3Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; 4Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Italy
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P07 | DISRUPTED GUT-VASCULAR BARRIER AND INFLAMMATORY REMODELING IN MNGIE: A SPATIAL TRANSCRIPTOMIC AND HISTOLOGICAL STUDY S. Blando1, E. Boschetti1, I. Neri1, L. Caporali2, C. Fiorini2, D. Ormanbekova2, C. Malagelada3, I. Rusciano1, V. Carelli2, R. De Giorgio4, L. Manzoli1, S. Ratti1 | 1Center of Clinical Surgical Molecular and Experimental Anatomy Alma Mater Studiorum, University of Bologna, Italy; 2IRCCS Institute of Neurological Sciences of Bologna, Neurogenetics Program, Bologna, Italy; 3Departament de Medicina, Universitat Autonoma de Barcelona, Barcelona, Spain; 4Department of Translational Medicine, University of Ferrara, Ferrara, Italy
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