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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

1.9
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3.7
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1.9
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3.7
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  • Histopathological and immunofluorescent characterization of post-sepsis immune dysregulation in a clinically relevant mouse model

    Haoran Tang, Chen Liao, Ning Tang, Hui Li, Yi Liu, Lingling Wang, Zongfang Ren
    12-02-2026
    https://doi.org/10.4081/ejh.2026.4435
    825
    PDF: 506
    HTML: 52
  • Pre-treatment with galectin-1 attenuates lipopolysaccharide-induced myocarditis by regulating the Nrf2 pathway

    Liying Shen, Kongjie Lu, Zhenfeng Chen, Yingwei Zhu, Cong Zhang, Li Zhang
    07-12-2023
    https://doi.org/10.4081/ejh.2023.3816
    1396
    PDF: 845
    HTML: 79
  • Extracellular vesicles from bone mesenchymal stem cells transport microRNA-206 into osteosarcoma cells and target NRSN2 to block the ERK1/2-Bcl-xL signaling pathway

    Alimu Keremu, Pazila Aila, Aikebaier Tusun , Maimaitiaili Abulikemu, Xiaoguang Zou
    22-06-2022
    https://doi.org/10.4081/ejh.2022.3394
    2307
    PDF: 1475
    HTML: 64
  • Astragalus Ⅳ ameliorates the dry eye injury in rabbit model via MUC1-ErbB1 pathway

    Li Chu, Suhong Ma, Zhiwei Chen, Wenfu Cao
    01-04-2021
    https://doi.org/10.4081/ejh.2021.3198
    2039
    PDF: 1128
    HTML: 51
  • Effects of miR-939 and miR-376A on ulcerative colitis using a decoy strategy to inhibit NF-κB and NFAT expression

    Yongwei Lin, Zhipeng Zhou, Lang Xie, Yongsheng Huang, Zhenghua Qiu, Lili Ye, Chunhui Cui
    15-02-2022
    https://doi.org/10.4081/ejh.2022.3316
    2129
    PDF: 851
    HTML: 62
  • Epidermal growth factor-like domain multiple 7 (EGFL7): Expression and possible effect on biliary epithelium growth in cholangiocarcinoma

    Caterina L. Mammola, Antonella Vetuschi, Luigi Pannarale, Roberta Sferra, Romina Mancinelli
    30-11-2018
    https://doi.org/10.4081/ejh.2018.2971
    1683
    PDF: 901
    Supplementary: 246
    HTML: 54
  • Umbilical cord mesenchymal stem cells inhibited inflammation of bronchial epithelial cells by regulating Hedgehog pathway

    Qiong Lin, Tianxing Yu, Xiaohua Li, Xin Lin, Yong Fan, Liyu Xu
    12-12-2023
    https://doi.org/10.4081/ejh.2023.3908
    1882
    PDF: 657
    HTML: 59
  • Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice

    Nana Bao, Min Zhang, Ming Tang, Ziyi Shen, Shenglin Wang, Guohui Jiang
    20-04-2026
    https://doi.org/10.4081/ejh.2026.4548
    954
    PDF: 538
    Raw data: 129
    HTML: 58
  • Unexpected distribution of KRIT1 inside the nucleus: new insight in a complex molecular pathway

    S. Marzo, V. Galimberti, M. Biggiogera
    11-03-2014
    https://doi.org/10.4081/ejh.2014.2358
    3380
    PDF: 763
    Supplementary: 357
    HTML: 325
  • Thrombin regulates the ability of Schwann cells to support neuritogenesis and to maintain the integrity of the nodes of Ranvier

    Elena Pompili, Viviana Ciraci, Stefano Leone, Valerio De Franchis, Pietro Familiari, Roberto Matassa, Giuseppe Familiari, Ada Maria Tata, Lorenzo Fumagalli, Cinzia Fabrizi
    30-03-2020
    https://doi.org/10.4081/ejh.2020.3109
    2288
    PDF: 1038
    HTML: 77
  • Phosphorylation mutation impairs the promoting effect of spastin on neurite outgrowth without affecting its microtubule severing ability

    Yunlong Zhang, Xin He, Jianyu Zou, Jie Yang, Ao Ma, Minghui Tan
    12-01-2023
    https://doi.org/10.4081/ejh.2023.3594
    1690
    PDF: 917
    HTML: 69
  • Immunohistochemical distribution of insulin-, glucagon- and somatostatin-containing cells in the pancreas of Lake Van fish (Alburnus tarichi Güldenstädt, 1814) (Cyprinidae)

    Burak Kaptaner
    25-02-2019
    https://doi.org/10.4081/ejh.2019.2999
    2240
    PDF: 898
    HTML: 58
  • Investigating conversion of endplate chondrocytes induced by intermittent cyclic mechanical unconfined compression in three-dimensional cultures

    H.G. Xu, W. Zhang, Q. Zheng, Y.F. Yu, L.F. Deng, H. Wang, P. Liu, M. Zhang
    17-07-2014
    https://doi.org/10.4081/ejh.2014.2415
    1899
    PDF: 1079
    HTML: 408
  • Expression and role of cocaine-amphetamine regulated transcript (CART) in the proliferation of biliary epithelium

    Arianna Casini, Giorgio Vivacqua, Rosa Vaccaro, Anastasia Renzi, Stefano Leone, Luigi Pannarale, Antonio Franchitto, Paolo Onori, Romina Mancinelli, Eugenio Gaudio
    19-10-2023
    https://doi.org/10.4081/ejh.2023.3846
    2045
    PDF: 799
    HTML: 73
  • Distribution of alpha-synuclein in normal human jejunum and its relations with the chemosensory and neuroendocrine system

    Arianna Casini, Romina Mancinelli, Caterina Loredana Mammola, Luigi Pannarale, Piero Chirletti, Paolo Onori, Rosa Vaccaro
    02-11-2021
    https://doi.org/10.4081/ejh.2021.3310
    3229
    PDF: 1345
    HTML: 122
  • The possible prognostic role of histone deacetylase and transforming growth factor β/Smad signaling in high grade gliomas treated by radio-chemotherapy: a preliminary immunohistochemical study

    Roberta Sferra, Simona Pompili, Claudio Festuccia, Francesco Marampon, Giovanni L. Gravina, Luca Ventura, Ernesto Di Cesare, Sara Cicchinelli, Eugenio Gaudio, Antonella Vetuschi
    16-05-2017
    https://doi.org/10.4081/ejh.2017.2732
    2924
    PDF: 1195
    HTML: 191
  • Premature senescence in primary muscle cultures of myotonic dystrophy type 2 is not associated with p16 induction

    L.V. Renna, R. Cardani, A. Botta, G. Rossi, B. Fossati, E. Costa, G. Meola
    22-10-2014
    https://doi.org/10.4081/ejh.2014.2444
    2627
    PDF: 1246
    HTML: 562
  • Erratum - Autophagic degradation of farnesylated prelamin A as a therapeutic approach to lamin-linked progeria

    V. Cenni, C. Capanni, M. Columbaro, M. Ortolani, M.R. D'Apice, G. Novelli, M. Fini, S. Marmiroli, E. Scarano, N.M. Maraldi, S. Squarzoni, S. Prencipe, G. Lattanzi
    e42
    19-12-2013
    https://doi.org/10.4081/ejh.2013.e42
    2696
    PDF: 724
    HTML: 219
  • Ontogenic development of corticotrophs in fetal buffalo (Bubalus bubalis) pituitary gland

    M. A. Sandhu, A. A. Saeed, M. S. Khilji, R. H. Pasha, N. Mukhtar, M. S. Anjum
    30-01-2014
    https://doi.org/10.4081/ejh.2014.2292
    3583
    PDF: 826
    HTML: 672
  • Hepatocyte growth factor intervention to reduce myocardial injury and improve cardiac function on diabetic myocardial infarction rats

    Zaiyong Zhang, Cheng Long, Yufeng Guan, Mingcai Song
    30-07-2020
    https://doi.org/10.4081/ejh.2020.3142
    1561
    PDF: 856
    HTML: 48
  • Brain morphological defects in prolidase deficient mice: first report

    V. Insolia, V.M. Piccolini
    17-09-2014
    https://doi.org/10.4081/ejh.2014.2417
    2283
    PDF: 820
    HTML: 355
  • Forever particles: histochemistry in the plasticene age

    Beatrice Camia, Andrea Casasco, Manuela Monti
    01-08-2025
    https://doi.org/10.4081/ejh.2025.4226
    1688
    PDF: 793
    HTML: 104
  • Autofluorescence spectroscopy and imaging: a tool for biomedical research and diagnosis

    A.C. Croce, G. Bottiroli
    12-12-2014
    https://doi.org/10.4081/ejh.2014.2461
    15860
    PDF: 6574
    HTML: 8058
  • E-cadherin inhibits the proliferation and migration of human colorectal cancer cells through Hippo signaling pathway

    Zhijing Wang, Xiaohua Qin, Shanshan Liu, Yilei Wen, Bikan Lan, Hantao Liao, Haixian Wei
    26-05-2025
    https://doi.org/10.4081/ejh.2025.4196
    1739
    PDF: 757
    HTML: 59
  • MyD88/ERK/NFkB pathways and pro-inflammatory cytokines release in periodontal ligament stem cells stimulated by Porphyromonas gingivalis

    Francesca Diomede, Maria Zingariello, Marcos F.X.B. Cavalcanti, Ilaria Merciaro, Jacopo Pizzicannella, Natalia de Isla, Sergio Caputi, Patrizia Ballerini, Oriana Trubiani
    24-05-2017
    https://doi.org/10.4081/ejh.2017.2791
    3634
    PDF: 1549
    HTML: 187
  • Localization of peripheral autonomic neurons innervating the boar urinary bladder trigone and neurochemical features of the sympathetic component

    L. Ragionieri, M. Botti, F. Gazza, C. Sorteni, R. Chiocchetti, P. Clavenzani, L. Bo, R. Panu
    e16
    06-05-2013
    https://doi.org/10.4081/ejh.2013.e16
    2652
    PDF: 1309
    HTML: 1071
  • Visnagin ameliorates myocardial ischemia/reperfusion injury through the promotion of autophagy and the inhibition of apoptosis

    Hai-rong Fu, Xiao-shan Li, Yong-hui Zhang, Bin-bin Feng, Lian-hong Pan
    07-09-2020
    https://doi.org/10.4081/ejh.2020.3131
    1480
    PDF: 1045
    HTML: 42
  • Ciliary neurotrophic factor (CNTF) and its receptor (CNTFRα) signal through MAPK/ERK pathway in human prostate tissues: a morphological and biomolecular study

    Sonia Fantone, Giovanni Tossetta, Rodolfo Montironi, Martina Senzacqua , Daniela Marzioni, Roberta Mazzucchelli
    19-10-2020
    https://doi.org/10.4081/ejh.2020.3147
    2336
    PDF: 944
    HTML: 60
  • Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function

    Zhijiang Chen, Huili Wang, Bin Hu, Xinxin Chen, Meiyu Zheng, Lili Liang, Juanjuan Lyu, Qiyi Zeng
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3412
    2833
    PDF: 1601
    HTML: 66
  • Immunolocalization of endocan during the endothelial-mesenchymal transition process

    L. M. Carrillo, E. Arciniegas, H. R. Rojas, R. E. Ramirez
    e13
    01-06-2011
    https://doi.org/10.4081/ejh.2011.e13
    1635
    PDF: 674
    HTML: 1432
  • Downregulation of SRPK2 promotes cell cycle arrest though E2F1 in non-small cell lung cancer

    Xin Li, Shaoyu Yang, Minna Zhang, Shuhuan Xie, Zefeng Xie
    11-12-2019
    https://doi.org/10.4081/ejh.2019.3067
    2399
    PDF: 1252
    HTML: 53
  • Twenty years of histochemistry in the third millennium, browsing the scientific literature

    Carlo Pellicciari
    29-12-2020
    https://doi.org/10.4081/ejh.2020.3213
    1565
    PDF: 635
    HTML: 44
  • Impact of Histochemistry on biomedical research: looking through the articles published in a long-established histochemical journal

    C. Pellicciari
    30-12-2014
    https://doi.org/10.4081/ejh.2014.2474
    2668
    PDF: 806
    HTML: 865
  • Dentin matrix protein 1 and dentin sialophosphoprotein in human sound and carious teeth: an immunohistochemical and colorimetric assay

    D. Martini, A. Trirè, L. Breschi, A. Mazzoni, G. Teti, M. Falconi, A. Ruggeri Jr
    e32
    29-10-2013
    https://doi.org/10.4081/ejh.2013.e32
    6166
    PDF: 1644
    HTML: 1015
  • 2D vs 3D morphological analysis of dorsal root ganglia in health and painful neuropathy

    Valentina Alda Carozzi, Chiara Salio, Virginia Rodriguez-Menendez, Elisa Ciglieri, Francesco Ferrini
    19-10-2021
    https://doi.org/10.4081/ejh.2021.3276
    3375
    PDF: 1884
    Video 1: 342
    Video 2: 383
    HTML: 54
  • Immunohistochemistry as a paramount tool in research of normal urothelium, bladder cancer and bladder pain syndrome

    Daša Zupančič, Rok Romih
    24-03-2021
    https://doi.org/10.4081/ejh.2021.3242
    2529
    PDF: 1452
    HTML: 54
  • Site-directed mutagenesis, in vivo electroporation and mass spectrometry in search for determinants of the subcellular targeting of Rab7b paralogue in the model eukaryote Paramecium octaurelia

    E. Wyroba, P. Kwaśniak, K. Miller, K. Kobyłecki, M. Osińska
    11-04-2016
    https://doi.org/10.4081/ejh.2016.2612
    2166
    PDF: 1239
    HTML: 374
  • The role of mutated SOD1 gene in synaptic stripping and MHC class I expression following nerve axotomy in ALS murine model

    Roman M. Kassa, Roberta Bonafede, Federico Boschi, Manuela Malatesta, Raffaella Mariotti
    17-05-2018
    https://doi.org/10.4081/ejh.2018.2904
    2426
    PDF: 849
    HTML: 57
  • Low ozone concentrations stimulate cytoskeletal organization, mitochondrial activity and nuclear transcription

    M. Costanzo, B. Cisterna, A. Vella, T. Cestari, V. Covi, G. Tabaracci, M. Malatesta
    21-04-2015
    https://doi.org/10.4081/ejh.2015.2515
    3472
    PDF: 1129
    HTML: 439
  • Super-resolution study of PIAS SUMO E3-ligases in hippocampal and cortical neurons

    Andrea Conz, Clara Alice Musi, Luca Russo, Tiziana Borsello, Luca Colnaghi
    11-08-2021
    https://doi.org/10.4081/ejh.2021.3241
    1879
    PDF: 873
    HTML: 43
  • Knockdown of miR-411-3p induces M2 macrophage polarization and promotes colorectal cancer progression by regulation of MMP7

    Tianliang Bai, Ping Li, Yabin Liu, Bindan Cai, Gang Li, Wenbin Wang, Rui Yan, Xiangkui Zheng, Shangkun Du
    05-05-2025
    https://doi.org/10.4081/ejh.2025.4178
    1311
    PDF: 550
    Supplementary: 119
    HTML: 99
  • CD44v6 expression in human skin keratinocytes as a possible mechanism for carcinogenesis associated with chronic arsenic exposure

    S. Huang, S. Guo, F. Guo, Q. Yang, X. Xiao, M. Murata, S. Ohnishi, S. Kawanishi, N. Ma
    e1
    14-01-2013
    https://doi.org/10.4081/ejh.2013.e1
    2412
    PDF: 1005
    HTML: 930
  • Reelin expression in human liver of patients with chronic hepatitis C infection

    Simone Carotti, Giuseppe Perrone, Michelina Amato, Umberto Vespasiani Gentilucci, Daniela Righi, Maria Francesconi, Claudio Pellegrini, Francesca Zalfa, Maria Zingariello, Antonio Picardi, Andrea Onetti Muda, Sergio Morini
    17-03-2017
    https://doi.org/10.4081/ejh.2017.2745
    3671
    PDF: 1114
    HTML: 398
  • Guilu Erxian oral liquid mitigates oxidative damage in spermatogonial cells via miR-6739-5p modulation and PI3K/AKT pathway activation: a functional histocytochemical study

    Zefeng Sun, Xinrong Fan, Zhenquan Liu
    02-10-2025
    https://doi.org/10.4081/ejh.2025.4253
    566
    PDF: 550
    HTML: 75
  • The role of galanin in the progression and prognosis of colorectal cancer: the unfinished story

    Zbigniew Kmiec, Jacek Kieżun, Bartlomiej E. Krazinski, Przemyslaw Kwiatkowski, Janusz Godlewski
    06-03-2024
    https://doi.org/10.4081/ejh.2024.3990
    1910
    PDF: 628
    HTML: 53
  • Histochemistry as an irreplaceable approach for investigating functional cytology and histology

    C. Pellicciari
    e41
    19-12-2013
    https://doi.org/10.4081/ejh.2013.e41
    3566
    PDF: 1064
    HTML: 456
  • A simplified immunohistochemical classification of skeletal muscle fibres in mouse

    M. Kammoun, I. Cassar-Malek, B. Meunier, B. Picard
    24-06-2014
    https://doi.org/10.4081/ejh.2014.2254
    5320
    PDF: 2003
    HTML: 1020
  • Mechanism of lovastatin in promoting ferroptosis of prostate cancer cells by regulating the mevalonate pathway

    Yanhong Xiao, Zhengdao Liu, Yougang Feng, Han Zhu, Bo Wang, Shulian Chen, Guobiao Liang
    23-07-2026
    https://doi.org/10.4081/ejh.2026.4575
    401
    PDF: 219
    HTML: 46
  • ON THE WAY TO A NEW MODEL OF NEURODEGENERATION? FIRST EVIDENCE OF THE EXPRESSION OF GATA1 IN THE BRAIN: CORRELATIONS WITH AGING, MITOCHONDRIAL DAMAGE AND SYNUCLEINOPATHY C. Caturano1, F. E. Bellomi1, F. Arciprete1, V. Velardi1, L. La Barbera2, M. Falchi3, M. Bacioglu4, R. Mancinelli5, M. D’Amelio2, M. Spillantini4, M. Zingariello1, G. Vivacqua1,6 | 1Laboratory of Microscopic and Ultrastructural Anatomy, Campus Biomedico University of Rome, Italy; 2Laboratory of Molecular Neuroscience - Campus Biomedico University of Rome, Italy; 3National Centre for HIV/AIDS Research, Istituto Superior di Sanità, Rome, Italy; 4Department of Clinical Neuroscience, The University of Cambridge, Cambridge, UK; 5Department of Anatomic, Histologic, Forensic Medicine and Locomotor Apparatus Science, Sapienza University of Rome, Italy; 6Department of Clinical Neuroscience, The University of Cambridge, Cambridge, UK

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4315
    418
  • The hematopoietic stem cells supportive megakaryocytes as shapers of the bone marrow niche

    Francesca Arciprete, Viola Velardi, Paola Verachi, Claudio Carta, Antonio Di Virgilio, Vincenzo Roberti, Giorgio Vivacqua, Rosalba Rana, Maria Zingariello
    16-12-2025
    https://doi.org/10.4081/ejh.2025.4424
    1327
    PDF: 434
    HTML: 53
  • Ion channels alterations in the forebrain of high-fat diet fed rats

    Proshanta Roy, Ilenia Martinelli, Michele Moruzzi, Federica Maggi, Consuelo Amantini, Maria Vittoria Micioni Di Bonaventura, Carlo Cifani, Francesco Amenta, Seyed Khosrow Tayebati, Daniele Tomassoni
    23-11-2021
    https://doi.org/10.4081/ejh.2021.3305
    2438
    PDF: 1277
    HTML: 77
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European Journal of Histochemistry

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