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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

1.9
Impact Factor 2025
3.7
CiteScore 2025
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1.9
Impact Factor 2025
3.7
CiteScore 2025
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  • Endoplasmic reticulum stress contributed to inflammatory bowel disease by activating p38 MAPK pathway

    Yan Long, Yan Zhao, Xiaoqing Ma, Ya Zeng, Tian Hu, Weijie Wu, Chongtian Deng, Jinyue Hu, Yueming Shen
    23-05-2022
    https://doi.org/10.4081/ejh.2022.3415
    2364
    PDF: 1172
    HTML: 58
  • Elevated caspase 3 expression correlates with severe inflammation in Crohn’s disease

    Nafie Sejdiu, Michael Naumann, Michael Vieth
    03-06-2026
    https://doi.org/10.4081/ejh.2026.4570
    140
    PDF: 74
    HTML: 4
  • Cryptotanshinone alleviates DSS-induced colitis in mouse by regulating the balance of Treg/Th17 cells and M1 macrophage activation

    Lin Liu, Wei Huang, Yu Wu, Guanlong Ye, Jing Zhang, Tong Shen, Changjuan Ouyang
    19-02-2026
    https://doi.org/10.4081/ejh.2026.4436
    556
    PDF: 326
    HTML: 12
  • Contribution of intestinal smooth muscle to Crohn's disease fibrogenesis

    C. Severi, R. Sferra, A. Scirocco, A. Vetuschi, N. Pallotta, A. Pronio, R. Caronna, G. Di Rocco, E. Gaudio, E. Corazziari, P. Onori
    17-12-2014
    https://doi.org/10.4081/ejh.2014.2457
    2951
    PDF: 1152
    HTML: 436
  • Deubiquitinase USP14 is upregulated in Crohn's disease and inhibits the NOD2 pathway mediated inflammatory response in vitro

    Mengling Li, Yan Zhao, Jiayi Zhang, Wang Jiang, Siyuan Peng, Jinyue Hu, Yueming Shen
    09-09-2024
    https://doi.org/10.4081/ejh.2024.4101
    1303
    PDF: 441
    HTML: 17
  • Effect of TNBS-induced colitis on enteric neuronal subpopulations in adult zebrafish

    Leen Uyttebroek, Casper Pype, Guy Hubens, Jean-Pierre Timmermans, Luc van Nassauw
    28-08-2020
    https://doi.org/10.4081/ejh.2020.3161
    2104
    PDF: 1224
    HTML: 22
  • From the intestinal mucosal barrier to the enteric neuromuscular compartment: an integrated overview on the morphological changes in Parkinson’s disease

    Carolina Pellegrini, Vanessa D'Antongiovanni, Chiara Ippolito, Cristina Segnani, Luca Antonioli, Matteo Fornai, Nunzia Bernardini
    22-11-2021
    https://doi.org/10.4081/ejh.2021.3278
    1538
    PDF: 852
    HTML: 42
  • Effects of miR-939 and miR-376A on ulcerative colitis using a decoy strategy to inhibit NF-κB and NFAT expression

    Yongwei Lin, Zhipeng Zhou, Lang Xie, Yongsheng Huang, Zhenghua Qiu, Lili Ye, Chunhui Cui
    15-02-2022
    https://doi.org/10.4081/ejh.2022.3316
    1862
    PDF: 745
    HTML: 29
  • Adipose-derived stem cells promote the recovery of intestinal barrier function by inhibiting the p38 MAPK signaling pathway

    Mei Yang, Wangbin Xu, Chaofu Yue, Rong Li, Xian Huang, Yongjun Yan, Qinyong Yan, Shisheng Liu, Yuan Liu, Qiaolin Li
    21-01-2025
    https://doi.org/10.4081/ejh.2025.4158
    1840
    PDF: 589
    Supplementary Figure: 89
    HTML: 60
  • Is mastocytic colitis a specific clinical-pathological entity?

    Filippo Vernia, Tiziana Tatti, Stefano Necozione, Annalisa Capannolo, Nicola Cesaro, Marco Magistroni, Marco Valvano, Simona Pompili, Roberta Sferra, Antonella Vetuschi, Giovanni Latella
    28-11-2022
    https://doi.org/10.4081/ejh.2022.3499
    1729
    PDF: 636
    HTML: 25
  • Identification of 5-hydroxytryptamine-producing cells by detection of fluorescence in paraffin-embedded tissue sections

    Y. Kaneko, N. Onda, Y. Watanabe, M. Shibutani
    29-09-2016
    https://doi.org/10.4081/ejh.2016.2684
    2235
    PDF: 835
    HTML: 311
  • Ferroptosis resistance cooperates with cellular senescence in the overt stage of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

    Antonella Vetuschi, Alfredo Cappariello, Paolo Onori, Eugenio Gaudio, Giovanni Latella, Simona Pompili, Roberta Sferra
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3391
    3708
    PDF: 1918
    HTML: 60
  • Histopathological and immunofluorescent characterization of post-sepsis immune dysregulation in a clinically relevant mouse model

    Haoran Tang, Chen Liao, Ning Tang, Hui Li, Yi Liu, Lingling Wang, Zongfang Ren
    12-02-2026
    https://doi.org/10.4081/ejh.2026.4435
    533
    PDF: 350
    HTML: 14
  • Characterization of kynurenine pathway in patients with diarrhea-predominant irritable bowel syndrome

    Pingping Li, Jimin Zheng, Yun Bai, Dingxin Wang, Zijin Cui, Yueqin Li, Jian Zhang, Yuzhen Wang
    19-06-2020
    https://doi.org/10.4081/ejh.2020.3132
    2210
    PDF: 1149
    HTML: 21
  • Localization of avβ6 integrin-TGF-β1/Smad3, mTOR and PPARγ in experimental colorectal fibrosis

    G. Latella, A. Vetuschi, R. Sferra, S. Speca, E. Gaudio
    e40
    04-12-2013
    https://doi.org/10.4081/ejh.2013.e40
    3756
    PDF: 1011
    HTML: 633
  • Cannabinoid CB2 receptors are involved in the protection of RAW264.7 macrophages against the oxidative stress: an in vitro study

    Sabrina Giacoppo, Agnese Gugliandolo, Oriana Trubiani, Federica Pollastro, Gianpaolo Grassi, Placido Bramanti, Emanuela Mazzon
    23-01-2017
    https://doi.org/10.4081/ejh.2017.2749
    6042
    PDF: 1364
    HTML: 402
  • Interaction between sphingosine kinase/sphingosine 1 phosphate and transforming growth factor-β/Smads pathways in experimental intestinal fibrosis. An in vivo immunohistochemical study

    Roberta Sferra, Simona Pompili, Luca Ventura, Caroline Dubuquoy, Silvia Speca, Eugenio Gaudio, Giovanni Latella, Antonella Vetuschi
    31-07-2018
    https://doi.org/10.4081/ejh.2018.2956
    1976
    PDF: 976
    Supplementary: 210
    HTML: 46
  • Novel understanding on genetic mechanisms of enteric neuropathies leading to severe gut dysmotility

    Francesca Bianco, Giulia Lattanzio, Luca Lorenzini, Chiara Diquigiovanni, Maurizio Mazzoni, Paolo Clavenzani, Laura Calzà, Luciana Giardino, Catia Sternini, Elena Bonora, Roberto De Giorgio
    25-11-2021
    https://doi.org/10.4081/ejh.2021.3289
    2457
    PDF: 1352
    HTML: 57
  • Effect of royal jelly on experimental colitis Induced by acetic acid and alteration of mast cell distribution in the colon of rats

    T. Karaca, F. Bayiroglu, M.U. Yoruk, S. Kaya, S. Uslu, B. Comba, L. Mis
    e35
    21-10-2010
    https://doi.org/10.4081/ejh.2010.e35
    3711
    PDF: 867
    HTML: 5317
  • Glycol methacrylate embedding for the histochemical study of the gastrointestinal tract of dogs naturally infected with Leishmania infantum

    A.J.W. Pinto, I.F.G. de Amorim, L.J. Pinheiro, I.M.V.M. Madeira, C.C. Souza, H. Chiarini-Garcia, M.V. Caliari, W.L. Tafuri
    26-10-2015
    https://doi.org/10.4081/ejh.2015.2546
    1756
    PDF: 735
    HTML: 1038
  • Expression of bone morphogenetic protein signaling pathway players in the jejunum and colon of adult rats

    Emma Cogo, Edwin Fouché, Charline Buisson, Adenike Omotoyinbo, Fabrice Pierre, Françoise Guéraud, Pascale Plaisancié
    21-08-2025
    https://doi.org/10.4081/ejh.2025.4174
    608
    PDF: 402
    HTML: 24
  • Immunohistochemical detection of putative pathogenetic factors in adhesions of infants: a pilot study

    Arvis Pauliņš, Anna Junga, Māra Pilmane
    10-02-2026
    https://doi.org/10.4081/ejh.2026.4438
    276
    PDF: 230
    HTML: 7
  • miR-19a targeting CLCA4 to regulate the proliferation, migration, and invasion of colorectal cancer cells

    Huiwen Li, Bo Huang
    10-03-2022
    https://doi.org/10.4081/ejh.2022.3381
    2083
    PDF: 707
    HTML: 28
  • The injury of serotonin on intestinal epithelium cell renewal of weaned diarrhoea mice

    Y. Dong, C. Yang, Z. Wang, Z. Qin, J. Cao, Y. Chen
    28-12-2016
    https://doi.org/10.4081/ejh.2016.2689
    2348
    PDF: 891
    HTML: 800
  • ECRG4 expression in normal rat tissues: expression study and literature review

    A. Porzionato, M. Rucinski, V. Macchi, G. Sarasin, L.K. Malendowicz, R. De Caro
    18-05-2015
    https://doi.org/10.4081/ejh.2015.2458
    3043
    PDF: 1172
    Supplementary: 386
    HTML: 1015
  • Autofluorescence spectroscopy and imaging: a tool for biomedical research and diagnosis

    A.C. Croce, G. Bottiroli
    12-12-2014
    https://doi.org/10.4081/ejh.2014.2461
    14269
    PDF: 6004
    HTML: 7973
  • High WTAP expression level as a promising biomarker for poor prognosis in colorectal cancer: a pilot study

    Michela Relucenti, Claudia Tito, Paolo Mercantini, Emanuela Pilozzi, Claudio Barbaranelli, Loredana Cristiano, Daniela Savarese, Daniela Bastianelli, Francesco Fazi, Vincenzo Petrozza, Xiaobo Li, Rui Chen, Selenia Miglietta, Giuseppe Familiari
    16-12-2024
    https://doi.org/10.4081/ejh.2024.4145
    1362
    PDF: 421
    HTML: 9
  • Substance P is overexpressed in cervical squamous cell carcinoma and promoted proliferation and invasion of cervical cancer cells in vitro

    Ying Wang, Shifa Yuan, Jing Ma, Hong Liu, Lizhen Huang, Fengzhen Zhang
    31-07-2023
    https://doi.org/10.4081/ejh.2023.3746
    1018
    PDF: 468
    HTML: 15
  • The possible prognostic role of histone deacetylase and transforming growth factor β/Smad signaling in high grade gliomas treated by radio-chemotherapy: a preliminary immunohistochemical study

    Roberta Sferra, Simona Pompili, Claudio Festuccia, Francesco Marampon, Giovanni L. Gravina, Luca Ventura, Ernesto Di Cesare, Sara Cicchinelli, Eugenio Gaudio, Antonella Vetuschi
    16-05-2017
    https://doi.org/10.4081/ejh.2017.2732
    2727
    PDF: 1015
    HTML: 155
  • BIOLOGICAL RESPONSE OF TREATMENT WITH SAFFRON PETAL EXTRACT ON CYTOKYNE-INDUCED OXIDATIVE STRESS AND INFLAMMATION IN THE CACO-2/THP1 COCOLTURE MODEL V. Panella1, F. De Cecco2, S. Franceschelli1, M. A. Maggi3, S. Bisti4, A. Bravo Nuevo5, D. D’Ardes1, F. Cipollone1, L. Speranza1 | 1Department of Medicine and Aging Sciences, University «G. D’Annunzio», Chieti; 2Italian Institute of Technology, Genoa, Italy; 3Hortus Novus, L’Aquila, Italy; 4National Institute of Biostructure and Biosystem, Rome, Italy; 5Department of Biomedical Sciences, Philadelphia College of Osteopathic Medicine (PCOM), Philadelphia, USA

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4320
    303
  • Localization of peripheral autonomic neurons innervating the boar urinary bladder trigone and neurochemical features of the sympathetic component

    L. Ragionieri, M. Botti, F. Gazza, C. Sorteni, R. Chiocchetti, P. Clavenzani, L. Bo, R. Panu
    e16
    06-05-2013
    https://doi.org/10.4081/ejh.2013.e16
    2482
    PDF: 1187
    HTML: 1040
  • The expression of innate immunity genes in Italian Crohn disease patients

    M Milanese, L Segat, N Marziliano, S Crovella
    199-202
    10-08-2009
    https://doi.org/10.4081/1142
    515
    PDF: 398
  • Effects of rutin on osteoblast MC3T3-E1 differentiation, ALP activity and Runx2 protein expression

    Xin-Wei Liu, Bin Ma, Ying Zi, Liang-Bi Xiang, Tian-Yu Han
    20-01-2021
    https://doi.org/10.4081/ejh.2021.3195
    3197
    PDF: 1501
    HTML: 33
  • Expression of S100β during mouse cochlear development

    Wenjing Liu, Yongchun Zhang, Cheng Liang, Lizhong Su
    10-03-2025
    https://doi.org/10.4081/ejh.2025.4189
    1436
    PDF: 392
    Supplementary: 75
    HTML: 9
  • miR-1270 enhances the proliferation, migration, and invasion of osteosarcoma via targeting cingulin

    Yang Liu, Weichun Guo, Shuo Fang, Bin He, Xiaohai Li, Li Fan
    07-12-2021
    https://doi.org/10.4081/ejh.2021.3237
    1539
    PDF: 580
    HTML: 27
  • Immunohistochemical expression of heparanase isoforms and syndecan-1 proteins in colorectal adenomas

    J. Waisberg, T.R. Theodoro, L.L. Matos, F.B. Orlandi, R.L. Serrano, G.T. Saba, M.A.S. Pinhal
    17-02-2016
    https://doi.org/10.4081/ejh.2016.2590
    2423
    PDF: 788
    HTML: 467
  • Knockdown of miR-411-3p induces M2 macrophage polarization and promotes colorectal cancer progression by regulation of MMP7

    Tianliang Bai, Ping Li, Yabin Liu, Bindan Cai, Gang Li, Wenbin Wang, Rui Yan, Xiangkui Zheng, Shangkun Du
    05-05-2025
    https://doi.org/10.4081/ejh.2025.4178
    927
    PDF: 400
    Supplementary: 52
    HTML: 50
  • Hsp10, Hsp70, and Hsp90 immunohistochemical levels change in ulcerative colitis after therapy

    G. Tomasello, C. Sciumé, F. Rappa, V. Rodolico, M. Zerilli, A. Martorana, G. Cicero, R. De Luca, P. Damiani, F.M. Accardo, M. Romeo, F. Farina, G. Bonaventura, G. Modica, G. Zummo, E. Conway de Macario, A.J.L. Macario, F. Cappello
    e38
    24-10-2011
    https://doi.org/10.4081/ejh.2011.e38
    2080
    PDF: 846
  • Comparison of different histological protocols for the preservation and quantification of the intestinal mucus layer in pigs

    Ilen Röhe, Friedrich Joseph Hüttner, Johanna Plendl, Barbara Drewes, Jürgen Zentek
    05-02-2018
    https://doi.org/10.4081/ejh.2018.2874
    4109
    PDF: 1757
    HTML: 276
  • Expression and role of cocaine-amphetamine regulated transcript (CART) in the proliferation of biliary epithelium

    Arianna Casini, Giorgio Vivacqua, Rosa Vaccaro, Anastasia Renzi, Stefano Leone, Luigi Pannarale, Antonio Franchitto, Paolo Onori, Romina Mancinelli, Eugenio Gaudio
    19-10-2023
    https://doi.org/10.4081/ejh.2023.3846
    1743
    PDF: 659
    HTML: 33
  • NADPH-diaphorase expression in the rat jejunum after intestinal ischemia/reperfusion

    A. Bolekova, T. Spakovska, D. Kluchova, S. Toth, J. Vesela
    e23
    13-07-2011
    https://doi.org/10.4081/ejh.2011.e23
    1601
    PDF: 648
    HTML: 1336
  • Low ozone concentrations do not exert cytoprotective effects on tamoxifen-treated breast cancer cells in vitro

    Chiara Rita Inguscio, Flavia Carton, Barbara Cisterna, Manuela Rizzi, Francesca Boccafoschi, Gabriele Tabaracci, Manuela Malatesta
    09-09-2024
    https://doi.org/10.4081/ejh.2024.4106
    1730
    PDF: 304
    HTML: 14
  • Twenty years of histochemistry in the third millennium, browsing the scientific literature

    Carlo Pellicciari
    29-12-2020
    https://doi.org/10.4081/ejh.2020.3213
    1375
    PDF: 539
    HTML: 15
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European Journal of Histochemistry

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pISSN: 1121-760X
eISSN: 2038-8306

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