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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

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  • Nuclear factor-kB and nitric oxide synthases in red blood cells: good or bad in obesity? A preliminary study

    Monika Široká, Caterina Franco, Zuzana Guľašová, Zdenka Hertelyová, Vladimíra Tomečková, Luigi F. Rodella, Rita Rezzani
    21-01-2020
    https://doi.org/10.4081/ejh.2020.3081
    1844
    PDF: 886
    HTML: 22
  • Characterization of kynurenine pathway in patients with diarrhea-predominant irritable bowel syndrome

    Pingping Li, Jimin Zheng, Yun Bai, Dingxin Wang, Zijin Cui, Yueqin Li, Jian Zhang, Yuzhen Wang
    19-06-2020
    https://doi.org/10.4081/ejh.2020.3132
    2315
    PDF: 1209
    HTML: 25
  • Dipeptidylpeptidase-­IV, a key enzyme for the degradation of incretins and neuropeptides: activity and expression in the liver of lean and obese rats

    E. Tarantola, V. Bertone, G. Milanesi, E. Capelli, A. Ferrigno, D. Neri, M. Vairetti, S. Barni, I. Freitas
    e41
    08-10-2012
    https://doi.org/10.4081/ejh.2012.e41
    1822
    PDF: 907
    HTML: 1091
  • Folic acid promotes autophagy to relieve metabolism-associated fatty liver disease by regulating NRF2

    Yu Wen, Juan Luo, Chunjing Shi, Jie Wu
    03-11-2025
    https://doi.org/10.4081/ejh.2025.4309
    1019
    PDF: 615
    HTML: 39
  • Study on the mechanism of Shenling Baizhu powder on the pathogenesis of pregnancy complicated with non-alcoholic fatty liver, based on PI3K/AKT/mTOR signal pathway

    Yao Le, Zhijun Wang, Qian Zhang, Ling Miao, Xiaohong Wang, Guorong Han
    17-09-2024
    https://doi.org/10.4081/ejh.2024.4093
    2415
    PDF: 647
    HTML: 61
  • Developmental immunolocalization of the Klotho protein in mouse kidney epithelial cells

    J.H. Song, M.Y. Lee, Y.J. Kim, S.R. Park, J. Kim, S.Y. Ryu, J.Y. Jung
    24-01-2014
    https://doi.org/10.4081/ejh.2014.2256
    3830
    PDF: 972
    HTML: 513
  • Histochemistry and immunolocalisation of glucokinin in antidiabetic plants used in traditional Mexican medicine

    Guillermo Laguna-Hernández, Carlos A. Rio-Zamorano, Itzel G. Meneses-Ochoa, Alicia E. Brechú-Franco
    21-06-2017
    https://doi.org/10.4081/ejh.2017.2782
    2541
    PDF: 1017
    HTML: 374
  • β-catenin mediates the effect of GLP-1 receptor agonist on ameliorating hepatic steatosis induced by high fructose diet

    Zhe Gao, Guang-Yao Song, Lu-Ping Ren, Hui-Juan Ma, Bo-Qing Ma, Shu-Chun Chen
    15-09-2020
    https://doi.org/10.4081/ejh.2020.3160
    1781
    PDF: 901
    HTML: 22
  • Ion channels alterations in the forebrain of high-fat diet fed rats

    Proshanta Roy, Ilenia Martinelli, Michele Moruzzi, Federica Maggi, Consuelo Amantini, Maria Vittoria Micioni Di Bonaventura, Carlo Cifani, Francesco Amenta, Seyed Khosrow Tayebati, Daniele Tomassoni
    23-11-2021
    https://doi.org/10.4081/ejh.2021.3305
    2295
    PDF: 1179
    HTML: 47
  • Cadmium influences the 5-Fluorouracil cytotoxic effects on breast cancer cells

    Y. Asara, J. A. Marchal, P. Bandiera, V. Mazzarello, L. G. Delogu, M. A. Sotgiu, A. Montella, R. Madeddu
    e1
    20-01-2012
    https://doi.org/10.4081/ejh.2012.e1
    1912
    PDF: 952
    HTML: 4625
  • Colchicine alleviates severe acute pancreatitis in rats by inhibiting acinar cell ferroptosis via LCN2/MAPK/ERK signaling axis

    Liu Yang, Xiaoyi Zheng, Yang Zhang, Yue Li, Lei Li, Feng Liu
    11-05-2026
    https://doi.org/10.4081/ejh.2026.4557
    436
    PDF: 558
    Supplementary: 49
    HTML: 8
  • The Qi-Bang-Yi-Shen formula ameliorates renal dysfunction and fibrosis in rats with diabetic kidney disease via regulating PI3K/AKT, ERK and PPARγ signaling pathways

    Zhi Wang, Guihua Jian, Teng Chen, Yiping Chen, Junhui Li, Niansong Wang
    01-03-2023
    https://doi.org/10.4081/ejh.2023.3648
    4918
    PDF: 1167
    HTML: 47
  • Alarin regulates RyR2 and SERCA2 to improve cardiac function in heart failure with preserved ejection fraction

    Jinshuang Li, Dawei Xu, Ce Shi, Chunqi Cheng, Ziheng Xu, Xingjuan Gao, Yong Cheng
    28-10-2024
    https://doi.org/10.4081/ejh.2024.4122
    1610
    PDF: 630
    HTML: 24
  • Ferroptosis resistance cooperates with cellular senescence in the overt stage of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

    Antonella Vetuschi, Alfredo Cappariello, Paolo Onori, Eugenio Gaudio, Giovanni Latella, Simona Pompili, Roberta Sferra
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3391
    4141
    PDF: 1979
    HTML: 65
  • Activation of the renin-angiotensin system in mice aggravates mechanical loading-induced knee osteoarthritis

    Kotaro Yamagishi, Ichiro Tsukamoto, Fumihisa Nakamura, Kazuhiko Hashimoto, Kazuhiro Ohtani, Masao Akagi
    24-07-2018
    https://doi.org/10.4081/ejh.2018.2930
    2071
    PDF: 1135
    HTML: 165
  • 2D vs 3D morphological analysis of dorsal root ganglia in health and painful neuropathy

    Valentina Alda Carozzi, Chiara Salio, Virginia Rodriguez-Menendez, Elisa Ciglieri, Francesco Ferrini
    19-10-2021
    https://doi.org/10.4081/ejh.2021.3276
    3180
    PDF: 1750
    Video 1: 268
    Video 2: 316
    HTML: 31
  • Spinosin ameliorates osteoarthritis through enhancing the Nrf2/HO-1 signaling pathway

    Peipei Lu, Shuxiang Li, Caoyang Zhang, Xinyi Jiang, Jinghua Xiang, Hong Xu, Jian Dong, Kun Wang, Yuhua Shi
    22-05-2024
    https://doi.org/10.4081/ejh.2024.4033
    1319
    PDF: 571
    HTML: 22
  • Dynamic of lipid droplets and gene expression in response to β-aminoisobutyric acid treatment on 3T3-L1 cells

    Monica Colitti, Federico Boschi, Tommaso Montanari
    28-11-2018
    https://doi.org/10.4081/ejh.2018.2984
    1839
    PDF: 1153
    HTML: 53
  • Decreased VEGFA alleviates the symptoms of LPS-induced sepsis in a mouse model by inhibiting glycolysis and thereby regulating the polarization of macrophages

    Jun Lin, Liping Jiang, Kun Guo, Ning Feng
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3528
    2101
    PDF: 1292
    Supplementary: 154
    HTML: 43
  • Molecules implicated in glucose homeostasis are differentially expressed in the trachea of lean and obese Zucker rats

    F. Merigo, F. Boschi, C. Lasconi, D. Benati, A. Sbarbati
    01-02-2016
    https://doi.org/10.4081/ejh.2016.2557
    2782
    PDF: 796
    HTML: 724
  • Histopathological and immunofluorescent characterization of post-sepsis immune dysregulation in a clinically relevant mouse model

    Haoran Tang, Chen Liao, Ning Tang, Hui Li, Yi Liu, Lingling Wang, Zongfang Ren
    12-02-2026
    https://doi.org/10.4081/ejh.2026.4435
    656
    PDF: 408
    HTML: 18
  • The selective blockade of metabotropic glutamate receptor-5 attenuates fat accumulation in an in vitro model of benign steatosis

    Andrea Ferrigno, Clarissa Berardo, Laura Giuseppina Di Pasqua, Marta Cagna, Veronica Siciliano, Plinio Richelmi, Mariapia Vairetti
    10-11-2020
    https://doi.org/10.4081/ejh.2020.3175
    1950
    PDF: 1003
    Supplementary: 204
    HTML: 34
  • Immunohistochemical identification of resistin in the uterus of ewes subjected to different diets: Preliminary results

    Cecilia Dall'Aglio, Paola Scocco, Margherita Maranesi, Linda Petrucci, Gabriele Acuti, Elena De Felice, Francesca Mercati
    03-05-2019
    https://doi.org/10.4081/ejh.2019.3020
    1811
    PDF: 1338
    HTML: 48
  • Lipid droplets characterization in adipocyte differentiated 3T3-L1 cells: size and optical density distribution

    V. Rizzatti, F. Boschi, M. Pedrotti, E. Zoico, A. Sbarbati, M. Zamboni
    e24
    06-08-2013
    https://doi.org/10.4081/ejh.2013.e24
    5061
    PDF: 1971
    HTML: 400
  • Lectin-like, oxidized low-density lipoprotein receptor-1-deficient mice show resistance to age-related knee osteoarthritis

    Kazuhiko Hashimoto, Yutaka Oda, Fumihisa Nakamura, Ryosuke Kakinoki, Masao Akagi
    14-02-2017
    https://doi.org/10.4081/ejh.2017.2762
    3092
    PDF: 989
    HTML: 258
  • The expression of Sirtuins 1 and 4 in peripheral blood leukocytes from patients with type 2 diabetes

    R. Song, W. Xu, Y. Chen, Z. Li, Y. Zeng, Y. Fu
    e10
    21-03-2011
    https://doi.org/10.4081/ejh.2011.e10
    2124
    PDF: 699
    HTML: 980
  • Immunofluorescent localization of ubiquitin and proteasomes in nucleolar vacuoles of soybean root meristematic cells

    D. Stępiński
    e13
    30-05-2012
    https://doi.org/10.4081/ejh.2012.13
    1213
    PDF: 506
    HTML: 1871
  • Relationship between lipid droplets size and integrated optical density

    Federico Boschi, Vanni Rizzatti, Elena Zoico, Tommaso Montanari, Mauro Zamboni, Andrea Sbarbati, Monica Colitti
    25-03-2019
    https://doi.org/10.4081/ejh.2019.3017
    1786
    PDF: 807
    HTML: 32
  • High glucose inhibits neural differentiation by excessive autophagy via peroxisome proliferator-activated receptor gamma

    Yin Pan, Di Qiu, Shu Chen, Xiaoxue Han, Ruiman Li
    11-05-2023
    https://doi.org/10.4081/ejh.2023.3691
    1377
    PDF: 938
    HTML: 26
  • Altered alkaline phosphatase activity in obese Zucker rats liver respect to lean Zucker and Wistar rats discussed in terms of all putative roles ascribed to the enzyme

    V. Bertone, E. Tarantola, A. Ferrigno, E. Gringeri, S. Barni, M. Vairetti, I. Freitas
    e5
    08-02-2011
    https://doi.org/10.4081/ejh.2011.e5
    1527
    PDF: 829
    HTML: 3577
  • <a href="https://it.freepik.com/vettori/sfondo">Sfondo vettore creata da pikisuperstar - it.freepik.com</a>

    DNA damage and repair in differentiation of stem cells and cells of connective cell lineages: A trigger or a complication?

    Nikolajs Sjakste, Una Riekstiņa
    03-05-2021
    https://doi.org/10.4081/ejh.2021.3236
    3353
    PDF: 1455
    HTML: 93
  • Low ozone concentrations promote in vitro preservation of explanted articular cartilage: an ultrastructural study

    Giada Remoli, Chiara Rita Inguscio, Federico Boschi, Gabriele Tabaracci, Manuela Malatesta, Barbara Cisterna
    26-01-2026
    https://doi.org/10.4081/ejh.2026.4440
    1326
    PDF: 280
    HTML: 16
  • P66 | FROM INNERVATION TO STEROIDOGENIC DEFECT: IMPLICATIONS OF CGRP IN THE PATHOPHYSIOLOGY OF POLYCYSTIC OVARY SYNDROME L. Sallicandro1, R. Gentile2, B. Filová3, S. Polakovičová3, A. Biagini1, F. Ballarino4, D. Del Bianco4, I. Varga5, A. Malvasi6, B. Fioretti2 | 1Department of Medicine and Surgery, University of Perugia, Perugia, Italy; 2Department of Chemistry, Biology and Biotechnologies, University of Perugia, Italy; 3Department of Histology and Embriology, Comenius University, Bratislava, Slovakia; 4Department of Chemistry, Biology and Biotechnologies, University of Perugia, Italy; 5Department of Histology and Embriology, Comenius University, Bratislava, Slovakia; 6Department of Biomedical Sciences and Human Oncology, Obstetrics and Gynecology Unit, University of Bari Aldo Moro, Bari, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4391
    368
  • NANOVESICLES IN THE GUT–BRAIN AXIS: INSIGHTS FROM PROBIOTIC SUPPLEMENTATION IN IRRITABLE BOWEL SYNDROME C. Caruso Bavisotto, F. Cappello | Section of Human Anatomy, Department of Biomedicine, Neuroscience and Advanced Diagnostics (BIND), University of Palermo, Palermo, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4318
    355
  • Histochemical detection of GM1 ganglioside using cholera toxin-B subunit. Evaluation of critical factors optimal for in situ detection with special emphasis to acetone pre-extraction

    T. Petr, V. Šmíd, J. Šmídová, H. Hůlková, M. Jirkovská, M. Elleder, L. Muchová, L. Vitek, F. Šmíd
    e23
    12-05-2010
    https://doi.org/10.4081/ejh.2010.e23
    1358
    PDF: 672
    HTML: 1854
  • Cartilage canals in newborn dogs: histochemical and immunohistochemical findings

    A. Di Giancamillo, M.E. Andreis, P. Taini, M.C. Veronesi, M. Di Giancamillo, S.C. Modina
    15-09-2016
    https://doi.org/10.4081/ejh.2016.2701
    1585
    PDF: 758
    Supplementary: 324
    HTML: 218
  • Quantitative evaluation of CART-containing cells in urinary bladder of rats with renovascular hypertension

    I. Janiuk, I. Kasacka
    13-04-2015
    https://doi.org/10.4081/ejh.2015.2446
    2229
    PDF: 700
    HTML: 403
  • P05 | ENTERIC NERVOUS SYSTEM NEUROPLASTICITY IN COLON OF ANIMAL MODELS OF OBESITY V. Bellitto1, I. Martinelli2, G. Nittari2, S.K. Tayebati2, D. Tomassoni1 | 1School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy; 2School of Medicinal and Health Products Sciences, University of Camerino, Camerino, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4325
    180
  • Connexin 43 expression in human and mouse testes with impaired spermatogenesis

    M Kotula-Balak, A Hejmej, J Sadowska, B Bilinska
    261-268
    10-08-2009
    https://doi.org/10.4081/1150
    539
    PDF: 681
  • Decellularized omentum as novel biologic scaffold for reconstructive surgery and regenerative medicine

    A. Porzionato, M. M. Sfriso, V. Macchi, A. Rambaldo, G. Lago, L. Lancerotto, V. Vindigni, R. De Caro
    e4
    24-01-2013
    https://doi.org/10.4081/ejh.2013.e4
    2498
    PDF: 1154
    HTML: 1093
  • Establishment and biological characteristics of a Jingning chicken embryonic fibroblast bank

    C. Bai, D. Wang, C. Li, D. Jin, C. Li, W. Guan, Y. Ma
    e4
    29-03-2011
    https://doi.org/10.4081/ejh.2011.e4
    1963
    PDF: 770
    HTML: 6766
  • P31 | MORPHOLOGICAL AND ULTRASTRUCTURAL MARKERS OF RADIATION-INDUCED ADIPOSE TISSUE DAMAGE E. Guerra1, S. Lattanzio1, G. Furini2, G. Scabia2, E. Mota-Silva2, M. Maffei2, S. Cinti3, R. Di Pietro1 | 1Department of Medicine and Ageing Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy; 2CNR Institute of Clinical Physiology, Pisa, Italy; 3Department of Experimental and Clinical Medicine, Center of Obesity, Università Politecnica delle Marche (Polytechnic University of Marche), Ancona, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4351
    212
  • Low ozone concentrations promote adipogenesis in human adipose-derived adult stem cells

    Manuela Costanzo, Federico Boschi, Flavia Carton, Giamaica Conti, Viviana Covi, Gabriele Tabaracci, Andrea Sbarbati, Manuela Malatesta
    03-09-2018
    https://doi.org/10.4081/ejh.2018.2969
    2717
    PDF: 862
    Supplementary: 380
    HTML: 47
  • Benzo[a]pyrene impairs the migratory pattern of human gonadotropin-releasing-hormone-secreting neuroblasts

    Giulia Guarnieri, Matteo Becatti, Paolo Comeglio, Linda Vignozzi, Mario Maggi, Gabriella Barbara Vannelli, Annamaria Morelli
    13-08-2021
    https://doi.org/10.4081/ejh.2021.3282
    1566
    PDF: 611
    HTML: 23
  • Double-labelling of astrocytes containing GFAP and KYNA or GFAP and 3-HAA

    Overexpression of kynurenic acid and 3-hydroxyanthranilic acid after rat traumatic brain injury

    Arturo Mangas, Margarita Heredia, Adelaida Riolobos, Antonio de la Fuente, José María Criado, Javier Yajeya, Michel Geffard, Rafael Coveñas
    14-11-2018
    https://doi.org/10.4081/ejh.2018.2985
    2296
    PDF: 858
    HTML: 31
  • 24 | ADMINISTRATION OF BRANCHED-CHAIN AMINO ACIDS AND DI-ALANINE MITIGATES MUSCLE ATROPHY IN A MOUSE MODEL OF CANCER CACHEXIA M. Colardo1, N. Martella1, M. Varone1, D. Pensabene1, G. Caretti2, G. Bianchini3, A. Aramini3, M. Segatto1 | 1Dept. of Biosciences and Territory, University of Molise, Italy; 2Dept. of Biosciences, University of Milan, Italy; 3Research & Early Development, Dompé Farmaceutici S.p.A., L’Aquila, Italy

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4642
    117
    PDF: 42
  • An in situ hybridization study of the insulin-like growth factor system in developing condylar cartilage of the fetal mouse mandible

    S. Shibata, H. Fukuoka, R. Sato, T. Abe, Y. Suzuki
    e23
    23-05-2012
    https://doi.org/10.4081/ejh.2012.23
    2351
    PDF: 740
    HTML: 5759
  • P03 | ALTERED NEUROTRANSMISSION AND METABOLISM IN A GFAP R239C ZEBRAFISH MODEL OF ALEXANDER DISEASE S. Candiani1|2, M. Bozzo1, V. Bazzurro1, D. Bellitto3, A. Tripi1, S. Ferrando1, G. Rosa1, T. Bacchetti3 | 1Dept. of Biology, University of Genova, Italy; 2RCCS Azienda Ospedaliera Metropolitana, Genova, Italy; 3UO Proteomica e Spettrometria di Massa, IRCCS Ospedale Policlinico San Martino, Genova, Italy

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4699
    130
    PDF: 40
  • Inhibition of HMGB1 suppresses inflammation and catabolism in temporomandibular joint osteoarthritis via NF-κB signaling pathway

    Yan Yan Li, Ya Ping Feng, Li Liu, Jin Ke, Xing Long
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3357
    2218
    PDF: 1163
    HTML: 42
  • Immunohistochemical and ultrastructural visualization of different routes of oocyte elimination in adult rats

    M.L. Escobar Sánchez, O.M. Echeverría Martínez, G.H. Vázquez-Nin
    e17
    16-04-2012
    https://doi.org/10.4081/ejh.2012.17
    1924
    PDF: 856
    HTML: 9437
  • Morphology, clearing efficacy, and mTOR dependency of the organelle autophagoproteasome

    Fiona Limanaqi, Francesca Biagioni, Alessandra Salvetti, Stefano Puglisi-Allegra, Paola Lenzi, Francesco Fornai
    01-06-2021
    https://doi.org/10.4081/ejh.2021.3220
    1480
    PDF: 551
    HTML: 22
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
Nana Bao et al.
20 April 2026
Vol. 70 No. 2 (2026)
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells
Huina Su et al.
21 April 2026
Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

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