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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

1.9
Impact Factor 2025
3.7
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1.9
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3.7
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  • DNMT1 regulates IL-6- and TGF-β1-induced epithelial mesenchymal transition in prostate epithelial cells

    Hui Xu, Yanbo Chen, Qi Chen, Huan Xu, Yanxia Wang, Jiao Yu, Juan Zhou, Zhong Wang, Bing Xu
    03-05-2017
    https://doi.org/10.4081/ejh.2017.2775
    2719
    PDF: 1046
    HTML: 185
  • Porphyromonas gingivalis lipopolysaccharide stimulation in human periodontal ligament stem cells: role of epigenetic modifications to the inflammation

    Francesca Diomede, Soundara Rajan Thangavelu, Ilaria Merciaro, Monica D'Orazio, Placido Bramanti, Emanuela Mazzon, Oriana Trubiani
    25-08-2017
    https://doi.org/10.4081/ejh.2017.2826
    3149
    PDF: 1318
    HTML: 144
  • PRMT1 arginine methyltransferase accumulates in cytoplasmic bodies that respond to selective inhibition and DNA damage

    J. Suchánková, S. Legartová, P. Sehnalová, S. Kozubek, S. Valente, D. Labella, A. Mai, C. Eckerich, F.O. Fackelmayer, D.V. Sorokin, E. Bartova
    02-05-2014
    https://doi.org/10.4081/ejh.2014.2389
    3131
    PDF: 765
    Supplementary: 321
    HTML: 814
  • Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model

    Juan Fan, Yu Ma, Liying Sun, Suhua Miao, Jianghong He
    20-04-2026
    https://doi.org/10.4081/ejh.2026.4533
    453
    PDF: 260
    HTML: 14
  • High WTAP expression level as a promising biomarker for poor prognosis in colorectal cancer: a pilot study

    Michela Relucenti, Claudia Tito, Paolo Mercantini, Emanuela Pilozzi, Claudio Barbaranelli, Loredana Cristiano, Daniela Savarese, Daniela Bastianelli, Francesco Fazi, Vincenzo Petrozza, Xiaobo Li, Rui Chen, Selenia Miglietta, Giuseppe Familiari
    16-12-2024
    https://doi.org/10.4081/ejh.2024.4145
    1425
    PDF: 588
    HTML: 9
  • ECRG4 expression in normal rat tissues: expression study and literature review

    A. Porzionato, M. Rucinski, V. Macchi, G. Sarasin, L.K. Malendowicz, R. De Caro
    18-05-2015
    https://doi.org/10.4081/ejh.2015.2458
    3093
    PDF: 1187
    Supplementary: 393
    HTML: 1018
  • Three dimensional analysis of histone methylation patterns in normal and tumor cell nuclei

    M Cremer, R Zinner, S Stein, H Albiez, B Wagler, C Cremer, T Cremer
    15-28
    29-06-2009
    https://doi.org/10.4081/855
    535
    PDF: 504
  • Localization of DNA methyltransferase-1 during oocyte differentiation, in vitro maturation and early embryonic development in cow

    V. Lodde, S. C. Modina, F. Franciosi, E. Zuccari, I. Tessaro, A. M. Luciano
    e24
    09-12-2009
    https://doi.org/10.4081/ejh.2009.e24
    1393
    PDF: 872
  • dCTP pyrophosphohydrase exhibits nucleic accumulation in multiple carcinomas

    Y. Zhang, W.Y. Ye, J.Q. Wang, S.J. Wang, P. Ji, G.Y. Zhou, G.P. Zhao, H.L. Ge, Y. Wang
    e29
    25-09-2013
    https://doi.org/10.4081/ejh.2013.e29
    3061
    PDF: 858
    HTML: 420
  • The possible prognostic role of histone deacetylase and transforming growth factor β/Smad signaling in high grade gliomas treated by radio-chemotherapy: a preliminary immunohistochemical study

    Roberta Sferra, Simona Pompili, Claudio Festuccia, Francesco Marampon, Giovanni L. Gravina, Luca Ventura, Ernesto Di Cesare, Sara Cicchinelli, Eugenio Gaudio, Antonella Vetuschi
    16-05-2017
    https://doi.org/10.4081/ejh.2017.2732
    2737
    PDF: 1047
    HTML: 156
  • DPY30 promotes the growth and survival of osteosarcoma cell by regulating the PI3K/AKT signal pathway

    Gong Cheng, Fengmin An, Zhilin Cao, Mingdi Zheng, Zhongyuan Zhao, Hao Wu
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3413
    1317
    PDF: 657
    Supplementary: 109
    HTML: 35
  • 68 | RESILIENCE ASSOCIATED WITH DEFECTS IN VITAMIN B12 METABOLISM: BALANCING BETWEEN HOMEOSTASIS AND DISEASE E. Selita1, E. Tomaselli2, G. Di Matteo3, L. Mannina3, M. Rossi2|4, D. Passeri2|4, L. Angeloni2|4, M. Fidaleo1|4 | 1Dept of Biology and Biotechnology, Charles Darwin, University of Rome Sapienza, Italy; 2Dept of Basic and Applied Sciences for Engineering, Sapienza University of Rome, Italy; 3Dept of Chemistry and Technology of Drugs, Sapienza University of Rome, Italy; 4Research Centre for Nanotechnology for Engineering of Sapienza (CNIS), Sapienza University of Rome, Italy

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4686
    85
    PDF: 26
  • KiSS1 inhibits growth and invasion of osteosarcoma cells through inhibition of the MAPK pathway

    Y. Zhang, Y.J. Tang, Z.H. Li, F. Pan, K. Huang, G.H. Xu
    e30
    29-10-2013
    https://doi.org/10.4081/ejh.2013.e30
    2859
    PDF: 717
    HTML: 315
  • Knockdown of ARHGAP30 inhibits ovarian cancer cell proliferation, migration, and invasiveness by suppressing the PI3K/AKT/mTOR signaling pathway

    Xiaoyan Chu, Jun Lou, Yun Yi, Linlin Zhong, Ouping Huang
    11-05-2023
    https://doi.org/10.4081/ejh.2023.3653
    1315
    PDF: 675
    HTML: 42
  • PDTC ameliorates neuropathic pain by inhibiting microglial activation via blockage of the TNFα-CX3CR1 pathway

    Xilei Li, Zhi Ye, Qulian Guo, E Wang, Yundan Pan
    12-03-2021
    https://doi.org/10.4081/ejh.2021.3184
    2220
    PDF: 923
    HTML: 21
  • Pleural mesothelioma from fluoro-edenite exposure: PACAP and PAC1 receptor. A preliminary report

    Claudia Lombardo, Grazia Maugeri, Agata Grazia D'Amico, Giuseppe Broggi, Rosario Caltabiano, Veronica Filetti, Serena Matera, Velia D'Agata, Carla Loreto
    02-05-2024
    https://doi.org/10.4081/ejh.2024.3994
    1623
    PDF: 526
    HTML: 33
  • Characterizing the activation of the Wnt signaling pathway in hilar cholangiocarcinoma using a tissue microarray approach

    W. Chen, J. Liang, L. Huang, J. Cai, Y. Lei, J. Lai, L. Liang, K. Zhang
    09-02-2016
    https://doi.org/10.4081/ejh.2016.2536
    1912
    PDF: 871
    HTML: 345
  • E-cadherin inhibits the proliferation and migration of human colorectal cancer cells through Hippo signaling pathway

    Zhijing Wang, Xiaohua Qin, Shanshan Liu, Yilei Wen, Bikan Lan, Hantao Liao, Haixian Wei
    26-05-2025
    https://doi.org/10.4081/ejh.2025.4196
    1264
    PDF: 554
    HTML: 20
  • Muc5ac mucin expression during rat skin development

    V. Ferretti, Á. Segal-Eiras, C.G. Barbeito, M.V. Croce
    20-02-2015
    https://doi.org/10.4081/ejh.2015.2462
    2538
    PDF: 849
    HTML: 721
  • The clinical significance of UBE2C gene in progression of renal cell carcinoma

    Zhiping Chen, Lanfeng Wang
    29-03-2021
    https://doi.org/10.4081/ejh.2021.3196
    1944
    PDF: 906
    HTML: 31
  • Immunofluorescent localization of ubiquitin and proteasomes in nucleolar vacuoles of soybean root meristematic cells

    D. Stępiński
    e13
    30-05-2012
    https://doi.org/10.4081/ejh.2012.13
    1196
    PDF: 476
    HTML: 1793
  • Essential Current Concepts in Stem Cell Biology

    Manuela Monti
    18-11-2020
    https://doi.org/10.4081/ejh.2020.3201
    2786
    PDF: 499
    HTML: 10
  • Expressions of ZNF436, β-catenin, EGFR, and CMTM5 in breast cancer and their clinical significances

    Zhi Chen, Na Cui, Ji-sen Zhao, Jian-fei Wu, Fang Ma, Cong Li, Xian-yi Liu
    20-01-2021
    https://doi.org/10.4081/ejh.2021.3173
    2363
    PDF: 833
    Supplementary: 188
    HTML: 19
  • Metallothionein expression and synthesis in the testis of the lizard Podarcis sicula under natural conditions and following estrogenic exposure

    Mariailaria Verderame, Ermelinda Limatola, Rosaria Scudiero
    03-05-2017
    https://doi.org/10.4081/ejh.2017.2777
    2037
    PDF: 714
    HTML: 163
  • Growth hormone inhibits the JAK/STAT3 pathway by regulating SOCS1 in endometrial cells in vitro: a clue to enhance endometrial receptivity in recurrent implantation failure

    Haixia Li, Ning Sun, Yaqiao Zhu, Wei Wang, Meihong Cai, Xiaohuan Luo, Wei Xia, Song Quan
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3580
    1700
    PDF: 985
    HTML: 50
  • Autophagic degradation of farnesylated prelamin A as a therapeutic approach to lamin-linked progeria

    V. Cenni, C. Capanni, M. Columbaro, M. Ortolani, M.R. D'Apice, G. Novelli, M. Fini, S. Marmiroli, E. Scarano, N.M. Maraldi, S. Squarzoni, S. Prencipe, G. Lattanzi
    e36
    19-10-2011
    https://doi.org/10.4081/ejh.2011.e36
    2886
    PDF: 1083
  • Role of Zip1 in the regulation of NPY expression by MLT to promote fracture healing in rats

    Junjun Shang, Bin Ma, Guiling Zhu, Penghong Dong, Chan Wang, Xiaochuan Gu, Ying Zi
    02-12-2020
    https://doi.org/10.4081/ejh.2020.3183
    1915
    PDF: 779
    HTML: 28
  • Identification of mechanism of the oncogenic role of FGFR1 in papillary thyroid carcinoma

    Xiong Bing Li, Jia Li Li, Chao Wang, Yong Zhang, Jing Li
    22-07-2024
    https://doi.org/10.4081/ejh.2024.4048
    2431
    PDF: 1364
    HTML: 22
  • Chromatin structure in situ: the contribution of DNA ultrastructural cytochemistry

    M. Derenzini, A. L. Olins, D. E. Olins
    24-01-2014
    https://doi.org/10.4081/ejh.2014.2307
    3685
    PDF: 1124
    Supplementary: 290
    HTML: 939
  • Docetaxel-resistant triple-negative breast cancer cell-derived exosomal lncRNA LINC00667 reduces the chemosensitivity of breast cancer cells to docetaxel via targeting miR-200b-3p/Bcl-2 axis

    Jindong Li, Jie Kang, Weiyan Liu, Jiazhe Liu, Gaofeng Pan, Anwei Mao, Qing Zhang, Jingfeng Lu, Junbin Ding, Hongchang Li
    25-10-2022
    https://doi.org/10.4081/ejh.2022.3529
    1806
    PDF: 841
    HTML: 38
  • Subcellular localization and distribution of the reduced folate carrier in normal rat tissues

    M. Hinken, S. Halwachs, C. Kneuer, W. Honscha
    e3
    27-01-2011
    https://doi.org/10.4081/ejh.2011.e3
    1930
    PDF: 731
    HTML: 5665
  • Digital PCR - Methods and Protocols

    Paolo Catarsi
    18-10-2019
    https://doi.org/10.4081/ejh.2019.3074
    2071
    PDF: 960
    HTML: 23
  • Role of water in chromosome spreading and swelling induced by acetic acid treatment: a FTIR spectroscopy study

    D. Ami, M. Di Segni, M. Forcella, V. Meraviglia, M. Baccarin, S.M. Doglia, G. Terzoli
    11-02-2014
    https://doi.org/10.4081/ejh.2014.2330
    3853
    PDF: 1016
    Supplementary: 271
    HTML: 729
  • PD-L1 expression with QR1 and E1L3N antibodies according to histological ovarian cancer subtype: A series of 232 cases

    Caroline Eymerit-Morin, Anna Ilenko, Thomas Gaillard, Justine Varinot, Eva Compérat, Sofiane Bendifallah, Emile Darai
    10-03-2021
    https://doi.org/10.4081/ejh.2021.3185
    1861
    PDF: 784
    HTML: 28
  • Colchicine alleviates severe acute pancreatitis in rats by inhibiting acinar cell ferroptosis via LCN2/MAPK/ERK signaling axis

    Liu Yang, Xiaoyi Zheng, Yang Zhang, Yue Li, Lei Li, Feng Liu
    11-05-2026
    https://doi.org/10.4081/ejh.2026.4557
    340
    PDF: 487
    Supplementary: 39
    HTML: 5
  • Aberrant DKK3 expression in the oral leukoplakia and oral submucous fibrosis: a comparative immunohistochemical study

    T. Al-dhohorah, M. Mashrah, Z. Yao, J. Huang
    16-06-2016
    https://doi.org/10.4081/ejh.2016.2629
    2775
    PDF: 865
    HTML: 348
  • Tumor cell-derived exosomal lncRNA LOC441178 inhibits the tumorigenesis of esophageal carcinoma through suppressing macrophage M2 polarization

    Jiangmu Chen, Zongchi Chen, Weitao Hu, Daxing Cai
    14-10-2022
    https://doi.org/10.4081/ejh.2022.3510
    1336
    PDF: 688
    HTML: 38
  • Histochemistry through the years, browsing a long-established journal: novelties in traditional subjects

    C. Pellicciari
    e51
    16-12-2010
    https://doi.org/10.4081/ejh.2010.e51
    1549
    PDF: 753
    HTML: 3896
  • Concomitant use of heat-shock protein 70, glutamine synthetase and glypican-3 is useful in diagnosis of HBV-related hepatocellular carcinoma with higher specificity and sensitivity

    Bita Moudi, Zahra Heidari, Hamidreza Mahmoudzadeh-Sagheb, Seyed-Moayed Alavian, Kamran B. Lankarani, Parisa Farrokh, Jens Randel Nyengaard
    29-01-2018
    https://doi.org/10.4081/ejh.2018.2859
    2317
    PDF: 1086
    HTML: 81
  • Senescence-associated ß-galactosidase staining over the lifespan differs in a short- and a long-lived fish species

    Simon Schöfer, Sylvia Laffer, Stefanie Kirchberger, Michael Kothmayer, Renate Löhnert, Elmar E. Ebner, Klara Weipoltshammer, Martin Distel, Oliver Pusch, Christian Schöfer
    29-02-2024
    https://doi.org/10.4081/ejh.2024.3977
    2282
    PDF: 1204
    Supplementary: 111
    HTML: 174
  • New bitongling (NBTL) ameliorates rheumatoid arthritis in rats through inhibiting JAK2/STAT3 signaling pathway

    Xiang Li, Yu Xie, An Kang, Yue Wang
    17-02-2021
    https://doi.org/10.4081/ejh.2021.3202
    2520
    PDF: 989
    HTML: 28
  • Immunohistochemical analysis of YB-1 expression in the developing mouse eye

    Alexander Forian Nass, Hella Wolf, Saadettin Sel , Thomas Kalinski, Norbert Nass
    03-11-2025
    https://doi.org/10.4081/ejh.2025.4244
    1591
    PDF: 260
    HTML: 25
  • Histochemistry for nucleic acid research: 60 years in the European Journal of Histochemistry

    Claudio Casali, Stella Siciliani, Lorena Zannino, Marco Biggiogera
    20-04-2022
    https://doi.org/10.4081/ejh.2022.3409
    1850
    PDF: 948
    HTML: 31
  • Protective effect of different antioxidant agents in UVB-irradiated keratinocytes

    Sara Salucci, Sabrina Burattini, Francesca Buontempo, Alberto Maria Martelli, Elisabetta Falcieri, Michela Battistelli
    18-09-2017
    https://doi.org/10.4081/ejh.2017.2784
    2529
    PDF: 1014
    HTML: 190
  • The role of miR-143-3p/FNDC1 axis on the progression of non-small cell lung cancer

    Zhanshu Ma, Qi Gao, Wenjing Xin, Lei Wang, Yan Chen, Chang Su, Songyan Gao, Ruiling Sun
    03-05-2023
    https://doi.org/10.4081/ejh.2023.3577
    2064
    PDF: 614
    HTML: 36
  • Ciliary neurotrophic factor (CNTF) and its receptor (CNTFRα) signal through MAPK/ERK pathway in human prostate tissues: a morphological and biomolecular study

    Sonia Fantone, Giovanni Tossetta, Rodolfo Montironi, Martina Senzacqua , Daniela Marzioni, Roberta Mazzucchelli
    19-10-2020
    https://doi.org/10.4081/ejh.2020.3147
    2166
    PDF: 805
    HTML: 22
  • Folic acid promotes autophagy to relieve metabolism-associated fatty liver disease by regulating NRF2

    Yu Wen, Juan Luo, Chunjing Shi, Jie Wu
    03-11-2025
    https://doi.org/10.4081/ejh.2025.4309
    905
    PDF: 565
    HTML: 35
  • Identification of abnormally high expression of POGZ as a new biomarker associated with a poor prognosis in osteosarcoma

    Sikuan Zheng, Yue Liu, Haohe Sun, Jingyu Jia, Tianlong Wu, Rui Ding, Xigao Cheng
    03-09-2021
    https://doi.org/10.4081/ejh.2021.3264
    2030
    PDF: 741
    Supplementary: 149
    HTML: 31
  • Expression of parafibromin in major renal cell tumors

    C. Cui, P. Lal, S. Master, Y. Ma, T. Baradet, Z. Bing
    e39
    23-10-2012
    https://doi.org/10.4081/ejh.2012.e39
    1514
    PDF: 664
    HTML: 226
  • miR-126 targeting GOLPH3 inhibits the epithelial-mesenchymal transition of gastric cancer BGC-823 cells and reduces cell invasion

    Jiancai Ouyang, Fuhu Song, He Li, Rui Yang, Haicheng Huang
    28-10-2020
    https://doi.org/10.4081/ejh.2020.3168
    1504
    PDF: 642
    HTML: 27
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
Nana Bao et al.
20 April 2026
Vol. 70 No. 2 (2026)
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells
Huina Su et al.
21 April 2026
Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

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pISSN: 1121-760X
eISSN: 2038-8306

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