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Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou

06-08-2025

https://doi.org/10.4081/ejh.2025.4228

1654

PDF: 860

HTML: 63
Emodin improves renal fibrosis in chronic kidney disease by regulating mitochondrial homeostasis through the mediation of peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC-1α)

Liuchang Feng, Zaoqiang Lin, Zeyong Tang, Lin Zhu, Shu Xu, Xi Tan, Xinyuan Wang, Jianling Mai, Qinxiang Tan

13-05-2024

https://doi.org/10.4081/ejh.2024.3917

2428

PDF: 998

HTML: 90
Independent and interactive roles of hirudin and HMGB1 interference in protecting renal function by regulating autophagy, apoptosis, and kidney injury in chronic kidney disease

Ying Li, Xuan Gao, Yao Chen, Huihui Li, Jing Tang, Wei Sun

07-04-2025

https://doi.org/10.4081/ejh.2025.4182

1472

PDF: 882

HTML: 92
Downregulation of S100 calcium-binding A4 (S100A4) ameliorates hepatic fibrosis via regulating Wnt/β-catenin signaling pathway

Chixian Zhang, Kai Bai, Dexu Li

14-04-2025

https://doi.org/10.4081/ejh.2025.4186

1651

PDF: 635

HTML: 68
Localization of avβ6 integrin-TGF-β1/Smad3, mTOR and PPARγ in experimental colorectal fibrosis

G. Latella, A. Vetuschi, R. Sferra, S. Speca, E. Gaudio

e40

04-12-2013

https://doi.org/10.4081/ejh.2013.e40

3956

PDF: 1141

HTML: 670
Molecular characterization of nephron progenitors and their early epithelial derivative structures in the nephrogenic zone of the canine fetal kidney

Rawah Faraj, Angela Irizarry-Alfonzo, Pawan Puri

23-09-2019

https://doi.org/10.4081/ejh.2019.3049

1737

PDF: 948

HTML: 87
Combination of tolvaptan and valsartan improves cardiac and renal functions in doxorubicin-induced heart failure in mice

Fengqin Yan, Hong Zhu, Yingxia He, Qinqin Wu, Xiaoyu Duan

11-11-2022

https://doi.org/10.4081/ejh.2022.3563

2037

PDF: 1009

Supplementary: 199

HTML: 70
The Qi-Bang-Yi-Shen formula ameliorates renal dysfunction and fibrosis in rats with diabetic kidney disease via regulating PI3K/AKT, ERK and PPARγ signaling pathways

Zhi Wang, Guihua Jian, Teng Chen, Yiping Chen, Junhui Li, Niansong Wang

01-03-2023

https://doi.org/10.4081/ejh.2023.3648

5495

PDF: 1275

HTML: 91
Interaction between sphingosine kinase/sphingosine 1 phosphate and transforming growth factor-β/Smads pathways in experimental intestinal fibrosis. An in vivo immunohistochemical study

Roberta Sferra, Simona Pompili, Luca Ventura, Caroline Dubuquoy, Silvia Speca, Eugenio Gaudio, Giovanni Latella, Antonella Vetuschi

31-07-2018

https://doi.org/10.4081/ejh.2018.2956

2168

PDF: 1112

Supplementary: 289

HTML: 72
Species diversity regarding the presence of proximal tubular progenitor cells of the kidney

J. Hansson, A.E. Ericsson, H. Axelson, M.E. Johansson

05-02-2016

https://doi.org/10.4081/ejh.2016.2567

2236

PDF: 884

Supplementary: 375

HTML: 409
Receptor-mediated endocytosis of lysozyme in renal proximal tubules of the frog Rana temporaria

E.V. Seliverstova, N.P. Prutskova

13-04-2015

https://doi.org/10.4081/ejh.2015.2482

2734

PDF: 935

HTML: 1172
Discovering ferroptosis in biliary epithelium during liver fibrosis

Romina Mancinelli, Arianna Casini, Stefano Leone, Ludovica Ceci, Rosa Vaccaro, Antonella Di Sotto, Giorgio Vivacqua, Rosemarie Heyn, Ludovica Garro, Marco Tagliafierro, Filippo Maria Bassi, Emanuele Bocci, Andrea Bassi, Luigi Pannarale, Antonio Franchitto, Paolo Onori, Eugenio Gaudio

28-10-2026

https://doi.org/10.4081/ejh.2026.4615

124

PDF: 102

HTML: 3
Aberrant DKK3 expression in the oral leukoplakia and oral submucous fibrosis: a comparative immunohistochemical study

T. Al-dhohorah, M. Mashrah, Z. Yao, J. Huang

16-06-2016

https://doi.org/10.4081/ejh.2016.2629

2989

PDF: 970

HTML: 376
Histochemical characterization of TDAG51 in endothelial remodeling and angiogenesis following myocardial infarction via PI3K-AKT signaling

Kaizheng Liu, Jinyu Pan, Quan Liu, Yang Huang, Liqun Shang, Yi Zhang, Jinming Wen, Huayang Li, Zhongkai Wu

15-06-2026

https://doi.org/10.4081/ejh.2026.4569

349

PDF: 294

HTML: 52
Immunohistochemical detection of putative pathogenetic factors in adhesions of infants: a pilot study

Arvis Pauliņš, Anna Junga, Māra Pilmane

10-02-2026

https://doi.org/10.4081/ejh.2026.4438

443

PDF: 584

HTML: 52
Expression of Ser729 phosphorylated PKCepsilon in experimental crescentic glomerulonephritis: an immunohistochemical study

V.N. Karavana, H. Gakiopoulou, E.A. Lianos

15-04-2014

https://doi.org/10.4081/ejh.2014.2308

2445

PDF: 1070

HTML: 681
Subcellular localization and distribution of the reduced folate carrier in normal rat tissues

M. Hinken, S. Halwachs, C. Kneuer, W. Honscha

e3

27-01-2011

https://doi.org/10.4081/ejh.2011.e3

2167

PDF: 826

HTML: 5948
Assessment of metal contaminants in non-small cell lung cancer by EDX microanalysis

M. Scimeca, A. Orlandi, I. Terrenato, S. Bischetti, E. Bonanno

12-09-2014

https://doi.org/10.4081/ejh.2014.2403

3808

PDF: 1165

HTML: 519
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells

Huina Su, Ruiqiong Ma, Dehui Su, Cheng Tan, Ye Zhu, Xin Yang

21-04-2026

https://doi.org/10.4081/ejh.2026.4537

1347

PDF: 782

HTML: 79
Expressions of ZNF436, β-catenin, EGFR, and CMTM5 in breast cancer and their clinical significances

Zhi Chen, Na Cui, Ji-sen Zhao, Jian-fei Wu, Fang Ma, Cong Li, Xian-yi Liu

20-01-2021

https://doi.org/10.4081/ejh.2021.3173

2610

PDF: 940

Supplementary: 261

HTML: 55
Immunolocalization of endocan during the endothelial-mesenchymal transition process

L. M. Carrillo, E. Arciniegas, H. R. Rojas, R. E. Ramirez

e13

01-06-2011

https://doi.org/10.4081/ejh.2011.e13

1632

PDF: 674

HTML: 1432
Autofluorescence spectroscopy and imaging: a tool for biomedical research and diagnosis

A.C. Croce, G. Bottiroli

12-12-2014

https://doi.org/10.4081/ejh.2014.2461

15848

PDF: 6570

HTML: 8057
Impact of Histochemistry on biomedical research: looking through the articles published in a long-established histochemical journal

C. Pellicciari

30-12-2014

https://doi.org/10.4081/ejh.2014.2474

2666

PDF: 805

HTML: 865
Aortic dissection is associated with reduced polycystin-1 expression, an abnormality that leads to increased ERK phosphorylation in vascular smooth muscle cells

J. Feng, S. Ge, L. Zhang, H. Che, C. Liang

16-12-2016

https://doi.org/10.4081/ejh.2016.2711

2812

PDF: 1284

HTML: 353
Different iron-handling in inflamed small and large cholangiocytes and in small and large-duct type intrahepatic cholangiocarcinoma

Romina Mancinelli, Antimo Cutone, Luigi Rosa, Maria Stefania Lepanto, Paolo Onori, Luigi Pannarale, Antonio Franchitto, Eugenio Gaudio, Piera Valenti

19-10-2020

https://doi.org/10.4081/ejh.2020.3156

2000

PDF: 878

HTML: 59
Is there still room for novelty, in histochemical papers?

Carlo Pellicciari

16-12-2016

https://doi.org/10.4081/ejh.2016.2758

3306

PDF: 837

HTML: 318
Histochemistry in biology and medicine: a message from the citing journals

Carlo Pellicciari

23-12-2015

https://doi.org/10.4081/ejh.2015.2610

3495

PDF: 1008

HTML: 936
Decreased expression of Met during differentiation in rat lung

T. Kato, K. Oka, T. Nakamura, A. Ito

01-02-2016

https://doi.org/10.4081/ejh.2016.2575

1803

PDF: 924

Supplementary: 388

HTML: 323
Radioprotective potential of histamine on rat small intestine and uterus

E. Carabajal, N. Massari, M. Croci, D. J. Martinel Lamas, J. P. Prestifilippo, R. M. Bergoc, E. S. Rivera, V. A. Medina

e48

18-12-2012

https://doi.org/10.4081/ejh.2012.e48

1571

PDF: 868

HTML: 945
Colchicine alleviates severe acute pancreatitis in rats by inhibiting acinar cell ferroptosis via LCN2/MAPK/ERK signaling axis

Liu Yang, Xiaoyi Zheng, Yang Zhang, Yue Li, Lei Li, Feng Liu

11-05-2026

https://doi.org/10.4081/ejh.2026.4557

672

PDF: 1088

Supplementary: 87

HTML: 42
Histochemistry as an irreplaceable approach for investigating functional cytology and histology

C. Pellicciari

e41

19-12-2013

https://doi.org/10.4081/ejh.2013.e41

3566

PDF: 1062

HTML: 456
Activation of the renin-angiotensin system in mice aggravates mechanical loading-induced knee osteoarthritis

Kotaro Yamagishi, Ichiro Tsukamoto, Fumihisa Nakamura, Kazuhiko Hashimoto, Kazuhiro Ohtani, Masao Akagi

24-07-2018

https://doi.org/10.4081/ejh.2018.2930

2189

PDF: 1219

HTML: 206
Changes in muscularis propria of anterior vaginal wall in women with pelvic organ prolapse

A. Vetuschi, A. D'Alfonso, R. Sferra, D. Zanelli, S. Pompili, F. Patacchiola, E. Gaudio, G. Carta

16-02-2016

https://doi.org/10.4081/ejh.2016.2604

2595

PDF: 1093

HTML: 675
Immunoreactivity of thymosin beta 4 in human foetal and adult genitourinary tract

S. Nemolato, T. Cabras, M.U. Fanari, F. Cau, D. Fanni, C. Gerosa, B. Manconi, I. Messana, M. Castagnola, G. Faa

e43

13-10-2010

https://doi.org/10.4081/ejh.2010.e43

1654

PDF: 688

HTML: 1033
Hepatocyte growth factor intervention to reduce myocardial injury and improve cardiac function on diabetic myocardial infarction rats

Zaiyong Zhang, Cheng Long, Yufeng Guan, Mingcai Song

30-07-2020

https://doi.org/10.4081/ejh.2020.3142

1560

PDF: 856

HTML: 48
miR-199a-5p inhibited HIF-1α to suppress the proliferation, migration, and differentiation of cardiac stem cells

Sha Li, Cuigai Zhang, Yanping Liu, Cuiqiao Meng, Yang Xie, Shuren Li

22-09-2025

https://doi.org/10.4081/ejh.2025.4239

719

PDF: 654

Supplementary: 115

HTML: 57
circRNA-79530 regulates Twist-mediated mitochondrial damage via sponging miR-214 affecting hypoxia/reoxygenation-induced injury in H9c2 cardiomyocytes

Ziyang Yu, Wenbo Xu, Yirong Teng, Tingting Li, Ren Guo, Ju Li, Xichen Li, Yanping Li, Yinglu Hao

22-08-2025

https://doi.org/10.4081/ejh.2025.4230

544

PDF: 457

HTML: 44
Astragalus Ⅳ ameliorates the dry eye injury in rabbit model via MUC1-ErbB1 pathway

Li Chu, Suhong Ma, Zhiwei Chen, Wenfu Cao

01-04-2021

https://doi.org/10.4081/ejh.2021.3198

2037

PDF: 1128

HTML: 51
Effects of miR-939 and miR-376A on ulcerative colitis using a decoy strategy to inhibit NF-κB and NFAT expression

Yongwei Lin, Zhipeng Zhou, Lang Xie, Yongsheng Huang, Zhenghua Qiu, Lili Ye, Chunhui Cui

15-02-2022

https://doi.org/10.4081/ejh.2022.3316

2128

PDF: 851

HTML: 62
Resveratrol mediates mitochondrial function through the sirtuin 3 pathway to improve abnormal metabolic remodeling in atrial fibrillation

Yuejuan Cao, Li Cui, Shaoyong Tuo, Hongze Liu, Shaonan Cui

24-04-2024

https://doi.org/10.4081/ejh.2024.4004

2326

PDF: 732

HTML: 55
Overexpression of GPER1 suppressed esophageal carcinoma growth via activating cAMP pathway

Hongmei Yin, Xiumei Han, Qun Zhang, Duojie Li, Fan Wang

26-01-2026

https://doi.org/10.4081/ejh.2026.4422

904

PDF: 517

Supplementary: 109

Original gels: 121

HTML: 58
Increased expression of STAT3 and SOCS3 in placenta from hyperglycemic rats

Vanessa Dela Justina, Sebastian San Martin, Daniela López-Espíndola, Alecsander F. M. Bressan, Raiany Alves de Freitas, Ana Maria Lopes de Passos, Juan Varas, Victor V. Lima, Fernanda R. Giachini

30-10-2019

https://doi.org/10.4081/ejh.2019.3054

1461

PDF: 979

HTML: 65
NR4A3 suppresses bladder cancer progression by modulating autophagy via the PI3K/AKT/mTOR pathway

Li Fan, Feng Xu, Shouyong Liu, Ding Wu, Suchun Wang, Xin Pan, Yulin Zhou, Le Qu, Wenquan Zhou

30-06-2025

https://doi.org/10.4081/ejh.2025.4221

1384

PDF: 630

HTML: 56
Transmission electron microscopy for nanomedicine: novel applications for long-established techniques

Manuela Malatesta

09-12-2016

https://doi.org/10.4081/ejh.2016.2751

2681

PDF: 1659

HTML: 303
Ferritin expression in the periodontal tissues of primates

Wenxue Huang, Wei Li, Juan Liu, Jianxia Hou, Huanxin Meng

03-09-2019

https://doi.org/10.4081/ejh.2019.3046

1512

PDF: 838

HTML: 52
Ozone and procaine increase secretion of platelet-derived factors in platelet-rich plasma

Chiara Rita Inguscio, Barbara Cisterna, Maria Assunta Lacavalla, Franco Donati, Osvaldo Angelini, Gabriele Tabaracci, Manuela Malatesta

10-10-2023

https://doi.org/10.4081/ejh.2023.3879

5108

PDF: 1024

HTML: 64
Low ozone concentrations do not exert cytoprotective effects on tamoxifen-treated breast cancer cells in vitro

Chiara Rita Inguscio, Flavia Carton, Barbara Cisterna, Manuela Rizzi, Francesca Boccafoschi, Gabriele Tabaracci, Manuela Malatesta

09-09-2024

https://doi.org/10.4081/ejh.2024.4106

2180

PDF: 420

HTML: 43
Docetaxel-resistant triple-negative breast cancer cell-derived exosomal lncRNA LINC00667 reduces the chemosensitivity of breast cancer cells to docetaxel via targeting miR-200b-3p/Bcl-2 axis

Jindong Li, Jie Kang, Weiyan Liu, Jiazhe Liu, Gaofeng Pan, Anwei Mao, Qing Zhang, Jingfeng Lu, Junbin Ding, Hongchang Li

25-10-2022

https://doi.org/10.4081/ejh.2022.3529

2013

PDF: 1010

HTML: 80

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