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Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou

06-08-2025

https://doi.org/10.4081/ejh.2025.4228

1338

PDF: 664

HTML: 23
Emodin improves renal fibrosis in chronic kidney disease by regulating mitochondrial homeostasis through the mediation of peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC-1α)

Liuchang Feng, Zaoqiang Lin, Zeyong Tang, Lin Zhu, Shu Xu, Xi Tan, Xinyuan Wang, Jianling Mai, Qinxiang Tan

13-05-2024

https://doi.org/10.4081/ejh.2024.3917

2033

PDF: 858

HTML: 50
Independent and interactive roles of hirudin and HMGB1 interference in protecting renal function by regulating autophagy, apoptosis, and kidney injury in chronic kidney disease

Ying Li, Xuan Gao, Yao Chen, Huihui Li, Jing Tang, Wei Sun

07-04-2025

https://doi.org/10.4081/ejh.2025.4182

1211

PDF: 719

HTML: 49
Downregulation of S100 calcium-binding A4 (S100A4) ameliorates hepatic fibrosis via regulating Wnt/β-catenin signaling pathway

Chixian Zhang, Kai Bai, Dexu Li

14-04-2025

https://doi.org/10.4081/ejh.2025.4186

1343

PDF: 487

HTML: 32
Localization of avβ6 integrin-TGF-β1/Smad3, mTOR and PPARγ in experimental colorectal fibrosis

G. Latella, A. Vetuschi, R. Sferra, S. Speca, E. Gaudio

e40

04-12-2013

https://doi.org/10.4081/ejh.2013.e40

3783

PDF: 1022

HTML: 633
Molecular characterization of nephron progenitors and their early epithelial derivative structures in the nephrogenic zone of the canine fetal kidney

Rawah Faraj, Angela Irizarry-Alfonzo, Pawan Puri

23-09-2019

https://doi.org/10.4081/ejh.2019.3049

1615

PDF: 827

HTML: 61
Combination of tolvaptan and valsartan improves cardiac and renal functions in doxorubicin-induced heart failure in mice

Fengqin Yan, Hong Zhu, Yingxia He, Qinqin Wu, Xiaoyu Duan

11-11-2022

https://doi.org/10.4081/ejh.2022.3563

1759

PDF: 882

Supplementary: 132

HTML: 35
The Qi-Bang-Yi-Shen formula ameliorates renal dysfunction and fibrosis in rats with diabetic kidney disease via regulating PI3K/AKT, ERK and PPARγ signaling pathways

Zhi Wang, Guihua Jian, Teng Chen, Yiping Chen, Junhui Li, Niansong Wang

01-03-2023

https://doi.org/10.4081/ejh.2023.3648

4241

PDF: 1088

HTML: 45
Interaction between sphingosine kinase/sphingosine 1 phosphate and transforming growth factor-β/Smads pathways in experimental intestinal fibrosis. An in vivo immunohistochemical study

Roberta Sferra, Simona Pompili, Luca Ventura, Caroline Dubuquoy, Silvia Speca, Eugenio Gaudio, Giovanni Latella, Antonella Vetuschi

31-07-2018

https://doi.org/10.4081/ejh.2018.2956

2007

PDF: 990

Supplementary: 211

HTML: 48
Species diversity regarding the presence of proximal tubular progenitor cells of the kidney

J. Hansson, A.E. Ericsson, H. Axelson, M.E. Johansson

05-02-2016

https://doi.org/10.4081/ejh.2016.2567

2041

PDF: 772

Supplementary: 310

HTML: 372
Receptor-mediated endocytosis of lysozyme in renal proximal tubules of the frog Rana temporaria

E.V. Seliverstova, N.P. Prutskova

13-04-2015

https://doi.org/10.4081/ejh.2015.2482

2535

PDF: 834

HTML: 1137
Aberrant DKK3 expression in the oral leukoplakia and oral submucous fibrosis: a comparative immunohistochemical study

T. Al-dhohorah, M. Mashrah, Z. Yao, J. Huang

16-06-2016

https://doi.org/10.4081/ejh.2016.2629

2763

PDF: 863

HTML: 348
Histochemical characterization of TDAG51 in endothelial remodeling and angiogenesis following myocardial infarction via PI3K-AKT signaling

Kaizheng Liu, Jinyu Pan, Quan Liu, Yang Huang, Liqun Shang, Yi Zhang, Jinming Wen, Huayang Li, Zhongkai Wu

15-06-2026

https://doi.org/10.4081/ejh.2026.4569

98

PDF: 93

HTML: 1
Immunohistochemical detection of putative pathogenetic factors in adhesions of infants: a pilot study

Arvis Pauliņš, Anna Junga, Māra Pilmane

10-02-2026

https://doi.org/10.4081/ejh.2026.4438

283

PDF: 359

HTML: 8
Expression of Ser729 phosphorylated PKCepsilon in experimental crescentic glomerulonephritis: an immunohistochemical study

V.N. Karavana, H. Gakiopoulou, E.A. Lianos

15-04-2014

https://doi.org/10.4081/ejh.2014.2308

2241

PDF: 929

HTML: 647
Subcellular localization and distribution of the reduced folate carrier in normal rat tissues

M. Hinken, S. Halwachs, C. Kneuer, W. Honscha

e3

27-01-2011

https://doi.org/10.4081/ejh.2011.e3

1926

PDF: 729

HTML: 5664
Assessment of metal contaminants in non-small cell lung cancer by EDX microanalysis

M. Scimeca, A. Orlandi, I. Terrenato, S. Bischetti, E. Bonanno

12-09-2014

https://doi.org/10.4081/ejh.2014.2403

3591

PDF: 1009

HTML: 482
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells

Huina Su, Ruiqiong Ma, Dehui Su, Cheng Tan, Ye Zhu, Xin Yang

21-04-2026

https://doi.org/10.4081/ejh.2026.4537

705

PDF: 473

HTML: 11
Expressions of ZNF436, β-catenin, EGFR, and CMTM5 in breast cancer and their clinical significances

Zhi Chen, Na Cui, Ji-sen Zhao, Jian-fei Wu, Fang Ma, Cong Li, Xian-yi Liu

20-01-2021

https://doi.org/10.4081/ejh.2021.3173

2357

PDF: 828

Supplementary: 188

HTML: 19
Immunolocalization of endocan during the endothelial-mesenchymal transition process

L. M. Carrillo, E. Arciniegas, H. R. Rojas, R. E. Ramirez

e13

01-06-2011

https://doi.org/10.4081/ejh.2011.e13

1457

PDF: 575

HTML: 1358
Autofluorescence spectroscopy and imaging: a tool for biomedical research and diagnosis

A.C. Croce, G. Bottiroli

12-12-2014

https://doi.org/10.4081/ejh.2014.2461

14442

PDF: 6056

HTML: 7984
Impact of Histochemistry on biomedical research: looking through the articles published in a long-established histochemical journal

C. Pellicciari

30-12-2014

https://doi.org/10.4081/ejh.2014.2474

2422

PDF: 697

HTML: 823
Aortic dissection is associated with reduced polycystin-1 expression, an abnormality that leads to increased ERK phosphorylation in vascular smooth muscle cells

J. Feng, S. Ge, L. Zhang, H. Che, C. Liang

16-12-2016

https://doi.org/10.4081/ejh.2016.2711

2651

PDF: 1141

HTML: 311
Different iron-handling in inflamed small and large cholangiocytes and in small and large-duct type intrahepatic cholangiocarcinoma

Romina Mancinelli, Antimo Cutone, Luigi Rosa, Maria Stefania Lepanto, Paolo Onori, Luigi Pannarale, Antonio Franchitto, Eugenio Gaudio, Piera Valenti

19-10-2020

https://doi.org/10.4081/ejh.2020.3156

1761

PDF: 771

HTML: 24
Is there still room for novelty, in histochemical papers?

Carlo Pellicciari

16-12-2016

https://doi.org/10.4081/ejh.2016.2758

2894

PDF: 726

HTML: 283
Histochemistry in biology and medicine: a message from the citing journals

Carlo Pellicciari

23-12-2015

https://doi.org/10.4081/ejh.2015.2610

3219

PDF: 886

HTML: 897
Decreased expression of Met during differentiation in rat lung

T. Kato, K. Oka, T. Nakamura, A. Ito

01-02-2016

https://doi.org/10.4081/ejh.2016.2575

1675

PDF: 781

Supplementary: 317

HTML: 281
Radioprotective potential of histamine on rat small intestine and uterus

E. Carabajal, N. Massari, M. Croci, D. J. Martinel Lamas, J. P. Prestifilippo, R. M. Bergoc, E. S. Rivera, V. A. Medina

e48

18-12-2012

https://doi.org/10.4081/ejh.2012.e48

1371

PDF: 735

HTML: 912
Colchicine alleviates severe acute pancreatitis in rats by inhibiting acinar cell ferroptosis via LCN2/MAPK/ERK signaling axis

Liu Yang, Xiaoyi Zheng, Yang Zhang, Yue Li, Lei Li, Feng Liu

11-05-2026

https://doi.org/10.4081/ejh.2026.4557

327

PDF: 480

Supplementary: 39

HTML: 5
Histochemistry as an irreplaceable approach for investigating functional cytology and histology

C. Pellicciari

e41

19-12-2013

https://doi.org/10.4081/ejh.2013.e41

3419

PDF: 902

HTML: 409
Changes in muscularis propria of anterior vaginal wall in women with pelvic organ prolapse

A. Vetuschi, A. D'Alfonso, R. Sferra, D. Zanelli, S. Pompili, F. Patacchiola, E. Gaudio, G. Carta

16-02-2016

https://doi.org/10.4081/ejh.2016.2604

2354

PDF: 942

HTML: 631
Immunoreactivity of thymosin beta 4 in human foetal and adult genitourinary tract

S. Nemolato, T. Cabras, M.U. Fanari, F. Cau, D. Fanni, C. Gerosa, B. Manconi, I. Messana, M. Castagnola, G. Faa

e43

13-10-2010

https://doi.org/10.4081/ejh.2010.e43

1513

PDF: 596

HTML: 966
Hepatocyte growth factor intervention to reduce myocardial injury and improve cardiac function on diabetic myocardial infarction rats

Zaiyong Zhang, Cheng Long, Yufeng Guan, Mingcai Song

30-07-2020

https://doi.org/10.4081/ejh.2020.3142

1418

PDF: 759

HTML: 18
miR-199a-5p inhibited HIF-1α to suppress the proliferation, migration, and differentiation of cardiac stem cells

Sha Li, Cuigai Zhang, Yanping Liu, Cuiqiao Meng, Yang Xie, Shuren Li

22-09-2025

https://doi.org/10.4081/ejh.2025.4239

511

PDF: 356

Supplementary: 58

HTML: 21
Activation of the renin-angiotensin system in mice aggravates mechanical loading-induced knee osteoarthritis

Kotaro Yamagishi, Ichiro Tsukamoto, Fumihisa Nakamura, Kazuhiko Hashimoto, Kazuhiro Ohtani, Masao Akagi

24-07-2018

https://doi.org/10.4081/ejh.2018.2930

2043

PDF: 1083

HTML: 161
circRNA-79530 regulates Twist-mediated mitochondrial damage via sponging miR-214 affecting hypoxia/reoxygenation-induced injury in H9c2 cardiomyocytes

Ziyang Yu, Wenbo Xu, Yirong Teng, Tingting Li, Ren Guo, Ju Li, Xichen Li, Yanping Li, Yinglu Hao

22-08-2025

https://doi.org/10.4081/ejh.2025.4230

393

PDF: 313

HTML: 9
Astragalus Ⅳ ameliorates the dry eye injury in rabbit model via MUC1-ErbB1 pathway

Li Chu, Suhong Ma, Zhiwei Chen, Wenfu Cao

01-04-2021

https://doi.org/10.4081/ejh.2021.3198

1852

PDF: 971

HTML: 25
Increased expression of STAT3 and SOCS3 in placenta from hyperglycemic rats

Vanessa Dela Justina, Sebastian San Martin, Daniela López-Espíndola, Alecsander F. M. Bressan, Raiany Alves de Freitas, Ana Maria Lopes de Passos, Juan Varas, Victor V. Lima, Fernanda R. Giachini

30-10-2019

https://doi.org/10.4081/ejh.2019.3054

1302

PDF: 845

HTML: 33
NR4A3 suppresses bladder cancer progression by modulating autophagy via the PI3K/AKT/mTOR pathway

Li Fan, Feng Xu, Shouyong Liu, Ding Wu, Suchun Wang, Xin Pan, Yulin Zhou, Le Qu, Wenquan Zhou

30-06-2025

https://doi.org/10.4081/ejh.2025.4221

983

PDF: 477

HTML: 21
Transmission electron microscopy for nanomedicine: novel applications for long-established techniques

Manuela Malatesta

09-12-2016

https://doi.org/10.4081/ejh.2016.2751

2431

PDF: 1531

HTML: 268
Ferritin expression in the periodontal tissues of primates

Wenxue Huang, Wei Li, Juan Liu, Jianxia Hou, Huanxin Meng

03-09-2019

https://doi.org/10.4081/ejh.2019.3046

1349

PDF: 735

HTML: 21
Ozone and procaine increase secretion of platelet-derived factors in platelet-rich plasma

Chiara Rita Inguscio, Barbara Cisterna, Maria Assunta Lacavalla, Franco Donati, Osvaldo Angelini, Gabriele Tabaracci, Manuela Malatesta

10-10-2023

https://doi.org/10.4081/ejh.2023.3879

4598

PDF: 790

HTML: 27
Low ozone concentrations do not exert cytoprotective effects on tamoxifen-treated breast cancer cells in vitro

Chiara Rita Inguscio, Flavia Carton, Barbara Cisterna, Manuela Rizzi, Francesca Boccafoschi, Gabriele Tabaracci, Manuela Malatesta

09-09-2024

https://doi.org/10.4081/ejh.2024.4106

1939

PDF: 308

HTML: 14
Docetaxel-resistant triple-negative breast cancer cell-derived exosomal lncRNA LINC00667 reduces the chemosensitivity of breast cancer cells to docetaxel via targeting miR-200b-3p/Bcl-2 axis

Jindong Li, Jie Kang, Weiyan Liu, Jiazhe Liu, Gaofeng Pan, Anwei Mao, Qing Zhang, Jingfeng Lu, Junbin Ding, Hongchang Li

25-10-2022

https://doi.org/10.4081/ejh.2022.3529

1798

PDF: 839

HTML: 38
Effects of miR-939 and miR-376A on ulcerative colitis using a decoy strategy to inhibit NF-κB and NFAT expression

Yongwei Lin, Zhipeng Zhou, Lang Xie, Yongsheng Huang, Zhenghua Qiu, Lili Ye, Chunhui Cui

15-02-2022

https://doi.org/10.4081/ejh.2022.3316

1884

PDF: 751

HTML: 29
Resveratrol mediates mitochondrial function through the sirtuin 3 pathway to improve abnormal metabolic remodeling in atrial fibrillation

Yuejuan Cao, Li Cui, Shaoyong Tuo, Hongze Liu, Shaonan Cui

24-04-2024

https://doi.org/10.4081/ejh.2024.4004

1981

PDF: 521

HTML: 25
Overexpression of GPER1 suppressed esophageal carcinoma growth via activating cAMP pathway

Hongmei Yin, Xiumei Han, Qun Zhang, Duojie Li, Fan Wang

26-01-2026

https://doi.org/10.4081/ejh.2026.4422

674

PDF: 396

Supplementary: 52

Original gels: 57

HTML: 17

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