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Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou

06-08-2025

https://doi.org/10.4081/ejh.2025.4228

1492

PDF: 766

HTML: 25
Emodin improves renal fibrosis in chronic kidney disease by regulating mitochondrial homeostasis through the mediation of peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC-1α)

Liuchang Feng, Zaoqiang Lin, Zeyong Tang, Lin Zhu, Shu Xu, Xi Tan, Xinyuan Wang, Jianling Mai, Qinxiang Tan

13-05-2024

https://doi.org/10.4081/ejh.2024.3917

2171

PDF: 923

HTML: 57
Independent and interactive roles of hirudin and HMGB1 interference in protecting renal function by regulating autophagy, apoptosis, and kidney injury in chronic kidney disease

Ying Li, Xuan Gao, Yao Chen, Huihui Li, Jing Tang, Wei Sun

07-04-2025

https://doi.org/10.4081/ejh.2025.4182

1291

PDF: 780

HTML: 51
Downregulation of S100 calcium-binding A4 (S100A4) ameliorates hepatic fibrosis via regulating Wnt/β-catenin signaling pathway

Chixian Zhang, Kai Bai, Dexu Li

14-04-2025

https://doi.org/10.4081/ejh.2025.4186

1513

PDF: 549

HTML: 35
Localization of avβ6 integrin-TGF-β1/Smad3, mTOR and PPARγ in experimental colorectal fibrosis

G. Latella, A. Vetuschi, R. Sferra, S. Speca, E. Gaudio

e40

04-12-2013

https://doi.org/10.4081/ejh.2013.e40

3845

PDF: 1077

HTML: 638
Molecular characterization of nephron progenitors and their early epithelial derivative structures in the nephrogenic zone of the canine fetal kidney

Rawah Faraj, Angela Irizarry-Alfonzo, Pawan Puri

23-09-2019

https://doi.org/10.4081/ejh.2019.3049

1647

PDF: 882

HTML: 63
Combination of tolvaptan and valsartan improves cardiac and renal functions in doxorubicin-induced heart failure in mice

Fengqin Yan, Hong Zhu, Yingxia He, Qinqin Wu, Xiaoyu Duan

11-11-2022

https://doi.org/10.4081/ejh.2022.3563

1898

PDF: 934

Supplementary: 155

HTML: 38
The Qi-Bang-Yi-Shen formula ameliorates renal dysfunction and fibrosis in rats with diabetic kidney disease via regulating PI3K/AKT, ERK and PPARγ signaling pathways

Zhi Wang, Guihua Jian, Teng Chen, Yiping Chen, Junhui Li, Niansong Wang

01-03-2023

https://doi.org/10.4081/ejh.2023.3648

5153

PDF: 1189

HTML: 48
Interaction between sphingosine kinase/sphingosine 1 phosphate and transforming growth factor-β/Smads pathways in experimental intestinal fibrosis. An in vivo immunohistochemical study

Roberta Sferra, Simona Pompili, Luca Ventura, Caroline Dubuquoy, Silvia Speca, Eugenio Gaudio, Giovanni Latella, Antonella Vetuschi

31-07-2018

https://doi.org/10.4081/ejh.2018.2956

2063

PDF: 1036

Supplementary: 232

HTML: 49
Species diversity regarding the presence of proximal tubular progenitor cells of the kidney

J. Hansson, A.E. Ericsson, H. Axelson, M.E. Johansson

05-02-2016

https://doi.org/10.4081/ejh.2016.2567

2080

PDF: 812

Supplementary: 322

HTML: 374
Receptor-mediated endocytosis of lysozyme in renal proximal tubules of the frog Rana temporaria

E.V. Seliverstova, N.P. Prutskova

13-04-2015

https://doi.org/10.4081/ejh.2015.2482

2607

PDF: 870

HTML: 1138
Aberrant DKK3 expression in the oral leukoplakia and oral submucous fibrosis: a comparative immunohistochemical study

T. Al-dhohorah, M. Mashrah, Z. Yao, J. Huang

16-06-2016

https://doi.org/10.4081/ejh.2016.2629

2843

PDF: 896

HTML: 351
Histochemical characterization of TDAG51 in endothelial remodeling and angiogenesis following myocardial infarction via PI3K-AKT signaling

Kaizheng Liu, Jinyu Pan, Quan Liu, Yang Huang, Liqun Shang, Yi Zhang, Jinming Wen, Huayang Li, Zhongkai Wu

15-06-2026

https://doi.org/10.4081/ejh.2026.4569

239

PDF: 184

HTML: 8
Immunohistochemical detection of putative pathogenetic factors in adhesions of infants: a pilot study

Arvis Pauliņš, Anna Junga, Māra Pilmane

10-02-2026

https://doi.org/10.4081/ejh.2026.4438

343

PDF: 476

HTML: 12
Expression of Ser729 phosphorylated PKCepsilon in experimental crescentic glomerulonephritis: an immunohistochemical study

V.N. Karavana, H. Gakiopoulou, E.A. Lianos

15-04-2014

https://doi.org/10.4081/ejh.2014.2308

2278

PDF: 987

HTML: 650
Subcellular localization and distribution of the reduced folate carrier in normal rat tissues

M. Hinken, S. Halwachs, C. Kneuer, W. Honscha

e3

27-01-2011

https://doi.org/10.4081/ejh.2011.e3

1977

PDF: 762

HTML: 5832
Assessment of metal contaminants in non-small cell lung cancer by EDX microanalysis

M. Scimeca, A. Orlandi, I. Terrenato, S. Bischetti, E. Bonanno

12-09-2014

https://doi.org/10.4081/ejh.2014.2403

3651

PDF: 1070

HTML: 486
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells

Huina Su, Ruiqiong Ma, Dehui Su, Cheng Tan, Ye Zhu, Xin Yang

21-04-2026

https://doi.org/10.4081/ejh.2026.4537

1044

PDF: 633

HTML: 23
Expressions of ZNF436, β-catenin, EGFR, and CMTM5 in breast cancer and their clinical significances

Zhi Chen, Na Cui, Ji-sen Zhao, Jian-fei Wu, Fang Ma, Cong Li, Xian-yi Liu

20-01-2021

https://doi.org/10.4081/ejh.2021.3173

2447

PDF: 875

Supplementary: 210

HTML: 22
Immunolocalization of endocan during the endothelial-mesenchymal transition process

L. M. Carrillo, E. Arciniegas, H. R. Rojas, R. E. Ramirez

e13

01-06-2011

https://doi.org/10.4081/ejh.2011.e13

1501

PDF: 607

HTML: 1395
Autofluorescence spectroscopy and imaging: a tool for biomedical research and diagnosis

A.C. Croce, G. Bottiroli

12-12-2014

https://doi.org/10.4081/ejh.2014.2461

15160

PDF: 6266

HTML: 8015
Impact of Histochemistry on biomedical research: looking through the articles published in a long-established histochemical journal

C. Pellicciari

30-12-2014

https://doi.org/10.4081/ejh.2014.2474

2471

PDF: 720

HTML: 826
Aortic dissection is associated with reduced polycystin-1 expression, an abnormality that leads to increased ERK phosphorylation in vascular smooth muscle cells

J. Feng, S. Ge, L. Zhang, H. Che, C. Liang

16-12-2016

https://doi.org/10.4081/ejh.2016.2711

2716

PDF: 1192

HTML: 315
Different iron-handling in inflamed small and large cholangiocytes and in small and large-duct type intrahepatic cholangiocarcinoma

Romina Mancinelli, Antimo Cutone, Luigi Rosa, Maria Stefania Lepanto, Paolo Onori, Luigi Pannarale, Antonio Franchitto, Eugenio Gaudio, Piera Valenti

19-10-2020

https://doi.org/10.4081/ejh.2020.3156

1821

PDF: 814

HTML: 26
Is there still room for novelty, in histochemical papers?

Carlo Pellicciari

16-12-2016

https://doi.org/10.4081/ejh.2016.2758

3011

PDF: 750

HTML: 284
Histochemistry in biology and medicine: a message from the citing journals

Carlo Pellicciari

23-12-2015

https://doi.org/10.4081/ejh.2015.2610

3291

PDF: 920

HTML: 901
Decreased expression of Met during differentiation in rat lung

T. Kato, K. Oka, T. Nakamura, A. Ito

01-02-2016

https://doi.org/10.4081/ejh.2016.2575

1708

PDF: 835

Supplementary: 343

HTML: 287
Radioprotective potential of histamine on rat small intestine and uterus

E. Carabajal, N. Massari, M. Croci, D. J. Martinel Lamas, J. P. Prestifilippo, R. M. Bergoc, E. S. Rivera, V. A. Medina

e48

18-12-2012

https://doi.org/10.4081/ejh.2012.e48

1462

PDF: 789

HTML: 914
Colchicine alleviates severe acute pancreatitis in rats by inhibiting acinar cell ferroptosis via LCN2/MAPK/ERK signaling axis

Liu Yang, Xiaoyi Zheng, Yang Zhang, Yue Li, Lei Li, Feng Liu

11-05-2026

https://doi.org/10.4081/ejh.2026.4557

490

PDF: 752

Supplementary: 51

HTML: 8
Histochemistry as an irreplaceable approach for investigating functional cytology and histology

C. Pellicciari

e41

19-12-2013

https://doi.org/10.4081/ejh.2013.e41

3454

PDF: 965

HTML: 413
Activation of the renin-angiotensin system in mice aggravates mechanical loading-induced knee osteoarthritis

Kotaro Yamagishi, Ichiro Tsukamoto, Fumihisa Nakamura, Kazuhiko Hashimoto, Kazuhiro Ohtani, Masao Akagi

24-07-2018

https://doi.org/10.4081/ejh.2018.2930

2085

PDF: 1147

HTML: 166
Changes in muscularis propria of anterior vaginal wall in women with pelvic organ prolapse

A. Vetuschi, A. D'Alfonso, R. Sferra, D. Zanelli, S. Pompili, F. Patacchiola, E. Gaudio, G. Carta

16-02-2016

https://doi.org/10.4081/ejh.2016.2604

2455

PDF: 997

HTML: 635
Immunoreactivity of thymosin beta 4 in human foetal and adult genitourinary tract

S. Nemolato, T. Cabras, M.U. Fanari, F. Cau, D. Fanni, C. Gerosa, B. Manconi, I. Messana, M. Castagnola, G. Faa

e43

13-10-2010

https://doi.org/10.4081/ejh.2010.e43

1548

PDF: 618

HTML: 998
Hepatocyte growth factor intervention to reduce myocardial injury and improve cardiac function on diabetic myocardial infarction rats

Zaiyong Zhang, Cheng Long, Yufeng Guan, Mingcai Song

30-07-2020

https://doi.org/10.4081/ejh.2020.3142

1464

PDF: 804

HTML: 24
miR-199a-5p inhibited HIF-1α to suppress the proliferation, migration, and differentiation of cardiac stem cells

Sha Li, Cuigai Zhang, Yanping Liu, Cuiqiao Meng, Yang Xie, Shuren Li

22-09-2025

https://doi.org/10.4081/ejh.2025.4239

611

PDF: 471

Supplementary: 76

HTML: 24
circRNA-79530 regulates Twist-mediated mitochondrial damage via sponging miR-214 affecting hypoxia/reoxygenation-induced injury in H9c2 cardiomyocytes

Ziyang Yu, Wenbo Xu, Yirong Teng, Tingting Li, Ren Guo, Ju Li, Xichen Li, Yanping Li, Yinglu Hao

22-08-2025

https://doi.org/10.4081/ejh.2025.4230

448

PDF: 374

HTML: 14
Astragalus Ⅳ ameliorates the dry eye injury in rabbit model via MUC1-ErbB1 pathway

Li Chu, Suhong Ma, Zhiwei Chen, Wenfu Cao

01-04-2021

https://doi.org/10.4081/ejh.2021.3198

1921

PDF: 1038

HTML: 28
Effects of miR-939 and miR-376A on ulcerative colitis using a decoy strategy to inhibit NF-κB and NFAT expression

Yongwei Lin, Zhipeng Zhou, Lang Xie, Yongsheng Huang, Zhenghua Qiu, Lili Ye, Chunhui Cui

15-02-2022

https://doi.org/10.4081/ejh.2022.3316

1984

PDF: 797

HTML: 33
Resveratrol mediates mitochondrial function through the sirtuin 3 pathway to improve abnormal metabolic remodeling in atrial fibrillation

Yuejuan Cao, Li Cui, Shaoyong Tuo, Hongze Liu, Shaonan Cui

24-04-2024

https://doi.org/10.4081/ejh.2024.4004

2145

PDF: 657

HTML: 28
Overexpression of GPER1 suppressed esophageal carcinoma growth via activating cAMP pathway

Hongmei Yin, Xiumei Han, Qun Zhang, Duojie Li, Fan Wang

26-01-2026

https://doi.org/10.4081/ejh.2026.4422

777

PDF: 446

Supplementary: 68

Original gels: 71

HTML: 26
Increased expression of STAT3 and SOCS3 in placenta from hyperglycemic rats

Vanessa Dela Justina, Sebastian San Martin, Daniela López-Espíndola, Alecsander F. M. Bressan, Raiany Alves de Freitas, Ana Maria Lopes de Passos, Juan Varas, Victor V. Lima, Fernanda R. Giachini

30-10-2019

https://doi.org/10.4081/ejh.2019.3054

1352

PDF: 884

HTML: 37
NR4A3 suppresses bladder cancer progression by modulating autophagy via the PI3K/AKT/mTOR pathway

Li Fan, Feng Xu, Shouyong Liu, Ding Wu, Suchun Wang, Xin Pan, Yulin Zhou, Le Qu, Wenquan Zhou

30-06-2025

https://doi.org/10.4081/ejh.2025.4221

1222

PDF: 543

HTML: 26
Transmission electron microscopy for nanomedicine: novel applications for long-established techniques

Manuela Malatesta

09-12-2016

https://doi.org/10.4081/ejh.2016.2751

2501

PDF: 1573

HTML: 270
Ferritin expression in the periodontal tissues of primates

Wenxue Huang, Wei Li, Juan Liu, Jianxia Hou, Huanxin Meng

03-09-2019

https://doi.org/10.4081/ejh.2019.3046

1381

PDF: 772

HTML: 24
Ozone and procaine increase secretion of platelet-derived factors in platelet-rich plasma

Chiara Rita Inguscio, Barbara Cisterna, Maria Assunta Lacavalla, Franco Donati, Osvaldo Angelini, Gabriele Tabaracci, Manuela Malatesta

10-10-2023

https://doi.org/10.4081/ejh.2023.3879

4839

PDF: 839

HTML: 32
Low ozone concentrations do not exert cytoprotective effects on tamoxifen-treated breast cancer cells in vitro

Chiara Rita Inguscio, Flavia Carton, Barbara Cisterna, Manuela Rizzi, Francesca Boccafoschi, Gabriele Tabaracci, Manuela Malatesta

09-09-2024

https://doi.org/10.4081/ejh.2024.4106

1997

PDF: 345

HTML: 17
Docetaxel-resistant triple-negative breast cancer cell-derived exosomal lncRNA LINC00667 reduces the chemosensitivity of breast cancer cells to docetaxel via targeting miR-200b-3p/Bcl-2 axis

Jindong Li, Jie Kang, Weiyan Liu, Jiazhe Liu, Gaofeng Pan, Anwei Mao, Qing Zhang, Jingfeng Lu, Junbin Ding, Hongchang Li

25-10-2022

https://doi.org/10.4081/ejh.2022.3529

1870

PDF: 911

HTML: 41

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