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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

2.1
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2.1
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  • Propofol alleviates M1 polarization and neuroinflammation of microglia in a subarachnoid hemorrhage model in vitro, by targeting the miR-140-5p/TREM-1/NF-κB signaling axis

    Lan Wang, Zhenyu Fan, Haijin Wang, Shougui Xiang
    17-09-2024
    https://doi.org/10.4081/ejh.2024.4034
    1052
    PDF: 506
    HTML: 7
  • Dexmedetomidine attenuates neuroinflammation and microglia activation in LPS-stimulated BV2 microglia cells through targeting circ-Shank3/miR-140-3p/TLR4 axis

    Guangbao He, Yibo He, Hongwei Ni, Kai Wang, Yijun Zhu, Yang Bao
    26-07-2023
    https://doi.org/10.4081/ejh.2023.3766
    1760
    PDF: 1153
    HTML: 13
  • Ghrelin reduces cerebral ischemic injury in rats by reducing M1 microglia/macrophages

    Rong Tian, Gengsheng Mao
    12-01-2022
    https://doi.org/10.4081/ejh.2022.3350
    1723
    PDF: 835
    HTML: 35
  • Ion channels alterations in the forebrain of high-fat diet fed rats

    Proshanta Roy, Ilenia Martinelli, Michele Moruzzi, Federica Maggi, Consuelo Amantini, Maria Vittoria Micioni Di Bonaventura, Carlo Cifani, Francesco Amenta, Seyed Khosrow Tayebati, Daniele Tomassoni
    23-11-2021
    https://doi.org/10.4081/ejh.2021.3305
    2064
    PDF: 1050
    HTML: 29
  • GAIT CHARACTERIZATION IN A MOUSE MODEL OF CHRONIC MILD STRESS- AND 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE-INDUCED NEUROINFLAMMATION Serinelli FC1, Kashyrina M2, De Nuccio F2, Panaro MA3, Cianciulli A3, Ruggiero M3, Porro C4, Ichas F5, Nicolardi N1 and Lofrumento DD1 | 1Department of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, Lecce, Italy; 2Department of Experimental Medicine, University of Salento, Lecce, Italy; 3Department of Biosciences, Biotechnologies and Environment, University of Bari, Italy; 4Department of Clinical and Experimental Medicine, University of Foggia, Italy; 5Institut des Maladies Neurodégénératives, CNRS, Université de Bordeaux, France

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4497
    173
  • A PRECLINICAL STUDY ON THE MODULATION OF THE MICROBIOTA–GUT–BRAIN AXIS BY A FUNCTIONAL SNACK PROMOTING HEALTHY AGING Bellitto V1, Grasselli F1, Martinelli I2, Nittari G2, Vittadini E1, Eleuteri AM1, Tayebati SK2, Bonfili L1 and Tomassoni D1 | 1School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy; 2School of Medicinal and Health Products Sciences, University of Camerino, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4465
    256
  • A NOVEL DRUG TARGETTING THE INFLAMMASOME AMELYORATES AD PATHOLOGY IN THE MURINE MODEL 5xFAD Chicote J1, Rosano V1, Mezzanotte M1, Bertinaria M2, Marini E2, Vercelli A1 and Stanga S1 | 1Neuroscience Institute Cavalieri Ottolenghi, Department of Neuroscience Rita Levi Montalcini, University of Turin, Italy; 2Department of Drug Science and Technology, University of Turin, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4485
    177
  • GLIAL INFLAMMASOME ACTIVATION AND BLOOD-BRAIN BARRIER BREAKDOWN IN AGE-RELATED NEURODEGENERATION Errede M1, Girolamo F1, d’Amati A1,2, de Giorgis M1, Lorusso L1, Pierucci C3, Bernardini N3, Pellegrini C3, Virgintino D1 and Annese T2 | 1University of Bari, Department of Translational Biomedicine and Neuroscience – Human Anatomy and Histology Unit, Bari, Italy; 2Libera Università del Mediterraneo (LUM) Giuseppe Degennaro University, Department of Medicine and Surgery, Bari, Italy; 3University of Pisa, Department of Clinical and Experimental Medicine - Unit of Histology and Medical Embryology, Pisa, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4460
    265
  • P17 | INTERMITTENT FASTING AND FUCOIDAN ADMINISTRATION AMELIORATE THE EFFECT OF TYPE 2 DIABETES ON ENTERIC NERVOUS SYSTEM IN RATS A.M. Cırık¹, B. Erdem¹, E. Akar ¹, E. Akkuş¹, Ö. İleri-Meşe², H. Maraş², Z.N. Özdemir-Kumral³, M. Yüksel⁴, Ö.T. Çilingir-Kaya² | 1Marmara Uni School of Medicine, Istanbul, Türkiye; 2Department of Histology and Embryology, Marmara Uni School of Medicine, Türkiye; 3Department of Physiology, Marmara Uni Faculty of Medicine, Türkiye; 4Department of Medical Laboratory Techniques, Vocational School of Health Services, Marmara Uni, Türkiye

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4337
    149
  • Long noncoding RNA Meg3 mediates ferroptosis induced by oxygen and glucose deprivation combined with hyperglycemia in rat brain microvascular endothelial cells, through modulating the p53/GPX4 axis

    Cheng Chen, Yan Huang, Pingping Xia, Fan Zhang, Longyan Li, E Wang, Qulian Guo, Zhi Ye
    30-09-2021
    https://doi.org/10.4081/ejh.2021.3224
    3289
    PDF: 1821
    HTML: 37
  • LOCUS COERULEUS STRUCTURAL INTEGRITY IS ASSOCIATED WITH CIRCULATING SOLUBLE AXL IN ALZHEIMER’S DISEASE Galgani A1, Scotto M2, Mary A3, Lombardo F4, Martini N4, Siciliano G5, Ceravolo R5, Heneka MT3,6 and Giorgi FS1,7 | 1Department of Translational Research and of New Surgical and Medical Technologies, University of Pisa, Pisa, Italy; 2Laboratory of Medical Science, Institute of Life Sciences, Scuola Superiore Sant’Anna, Pisa, Italy; 3Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg; 4Department of Radiology, Fondazione Toscana “G. Monasterio”, Pisa, Italy; 5Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; 6Division of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, USA; 7I.R.C.C.S. Stella Maris, Calambrone, Pisa, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4467
    235
  • Effects of piperlonguminine on lung injury in severe acute pancreatitis via the TLR4/NF-κB pathway

    Qian Hu, Ran Tao, Xiaoyun Hu, Haibo Wu, Jianjun Xu
    20-03-2023
    https://doi.org/10.4081/ejh.2023.3639
    1137
    PDF: 669
    HTML: 21
  • Forever particles: histochemistry in the plasticene age

    Beatrice Camia, Andrea Casasco, Manuela Monti
    01-08-2025
    https://doi.org/10.4081/ejh.2025.4226
    794
    PDF: 415
    HTML: 38
  • SHORT-TERM EXPOSURE TO PARTICULATE MATTER TRIGGERS SELECTIVE MOLECULAR AND BEHAVIORAL ALTERATIONS IN A MOUSE MODEL OF MULTIPLE SCLEROSIS Bonato M1,2, Montarolo F1,2, Cerrato V1,2, Parolisi R1,2, Abbadessa G3, Caudana M3, Di Cintio N1,2, De Francia S3, Bertolotto A2,4, Buffo A1,2, and Boda E1,2 | 1Dept. of Neuroscience Rita Levi Montalcini, University of Turin, Turin, Italy; 2Neuroscience Institute Cavalieri Ottolenghi, Orbassano (Turin), Italy; 3Department of Clinical and Biological Sciences, University of Turin, Orbassano (Turin), Italy; 4Koelliker Hospital, Turin, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4482
    216
  • Adipose mesenchymal stem cells-derived extracellular vesicles exert their preferential action in damaged central sites of SOD1 mice rather than peripherally

    Ermanna Turano, Federica Virla, Ilaria Scambi, Sylwia Dabrowska, Oluwamolakun Bankole, Raffaella Mariotti
    04-07-2024
    https://doi.org/10.4081/ejh.2024.4040
    1916
    PDF: 539
    HTML: 17
  • 2D vs 3D morphological analysis of dorsal root ganglia in health and painful neuropathy

    Valentina Alda Carozzi, Chiara Salio, Virginia Rodriguez-Menendez, Elisa Ciglieri, Francesco Ferrini
    19-10-2021
    https://doi.org/10.4081/ejh.2021.3276
    2819
    PDF: 1611
    Video 1: 224
    Video 2: 267
    HTML: 22
  • The possible alleviating effect of garlic supplement on the neural retina in a rat model of hypercholesterolemia: a histological and immunohistochemical study

    Eetmad A. Arafat, Eman M.I. Youssef, Hanaa A. Khalaf
    16-12-2021
    https://doi.org/10.4081/ejh.2021.3322
    1143
    PDF: 506
    HTML: 19
  • NEUROBIOLOGY OF SUICIDE: MORPHOLOGICAL ASSESSMENT OF MICROGLIAL NETWORK IN HUMAN POST-MORTEM PREFRONTAL CORTEX Tambuzzi S1, Bertolotto N2, Massari S2, Madaschi L3, Alini M2, Brandolese D2, Ubezio MC1, Cattaneo C1 and Amadeo A2 | 1Institute of Forensic Medicine, Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy; 2Department of Biosciences, Università degli Studi di Milano, Milan, Italy; 3UNITECH NOLIMITS, Università degli Studi di Milano, Milan, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4459
    243
  • Mast cells in meningiomas

    Antonio D'Amati, Roberto Tamma, Tiziana Annese, Anna Rizzi, Domenico Ribatti
    18-04-2024
    https://doi.org/10.4081/ejh.2024.3973
    1354
    PDF: 386
    HTML: 24
  • Cannabinoid CB2 receptors are involved in the protection of RAW264.7 macrophages against the oxidative stress: an in vitro study

    Sabrina Giacoppo, Agnese Gugliandolo, Oriana Trubiani, Federica Pollastro, Gianpaolo Grassi, Placido Bramanti, Emanuela Mazzon
    23-01-2017
    https://doi.org/10.4081/ejh.2017.2749
    5908
    PDF: 1320
    HTML: 396
  • miR-1270 enhances the proliferation, migration, and invasion of osteosarcoma via targeting cingulin

    Yang Liu, Weichun Guo, Shuo Fang, Bin He, Xiaohai Li, Li Fan
    07-12-2021
    https://doi.org/10.4081/ejh.2021.3237
    1404
    PDF: 541
    HTML: 23
  • Endothelial barrier antigen-immunoreactivity is conversely associated with blood-brain barrier dysfunction after embolic stroke in rats

    J. Pelz, W. Härtig, C. Weise, C. Hobohm, D. Schneider, M. Krueger, J. Kacza, D. Michalski
    e38
    18-12-2013
    https://doi.org/10.4081/ejh.2013.e38
    3347
    PDF: 792
    HTML: 231
  • A PILOT STUDY TO INVESTIGATE THE ANTIAGING EFFECTS OF THE OLIVE POMACE BY-PRODUCT ON THE BRAIN OF DROSOPHILA MELANOGASTER Makladissi S1†, Tomassoni D2†*, Nardin T3, Bellitto V2, Cappelli A2, Di Cara F1‡ and Beghelli D2‡ | 1Department of Microbiology and Immunology, Faculty of Medicine, Dalhousie University, Halifax, NS, Canada; 2School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, MC, Italy ; 3Chemical Unit Oenological Vines Agri-food - Technology Transfer Centre Foundation Edmund Mach, TN, Italy †These authors equally contributed. ‡These authors share the authorship

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4513
    177
  • Mucin1 relieves acute lung injury by inhibiting inflammation and oxidative stress

    Chunlin Ye, Bin Xu, Jie Yang, Yunkun Liu, Zhikai Zeng, Lingchun Xia, Quanjin Li, Guowen Zou
    02-12-2021
    https://doi.org/10.4081/ejh.2021.3331
    2422
    PDF: 1397
    HTML: 35
  • High glucose inhibits neural differentiation by excessive autophagy via peroxisome proliferator-activated receptor gamma

    Yin Pan, Di Qiu, Shu Chen, Xiaoxue Han, Ruiman Li
    11-05-2023
    https://doi.org/10.4081/ejh.2023.3691
    1198
    PDF: 824
    HTML: 21
  • An ex vivo study on immunohistochemical localization of MMP-7 and MMP-9 in temporomandibular joint discs with internal derangement

    C. Loreto, R. Leonardi, G. Musumeci, G. Pannone, S. Castorina
    e12
    15-04-2013
    https://doi.org/10.4081/ejh.2013.e12
    2758
    PDF: 817
    HTML: 429
  • Spatio-temporal course of macrophage-like cell accumulation after experimental embolic stroke depending on treatment with tissue plasminogen activator and its combination with hyperbaric oxygenation

    D. Michalski, M. Heindl, J. Kacza, F. Laignel, L. Küppers-Tiedt, D. Schneider, J. Grosche, J. Boltze, M. Löhr, C. Hobohm, W. Härtig
    e14
    09-05-2012
    https://doi.org/10.4081/ejh.2012.14
    6584
    PDF: 744
    HTML: 10423
  • KAEMPFEROL TARGETS LIPID BALANCE, ENDOCANNABINOID PATHWAYS, AND PPAR-α IN THE RAT CEREBRAL CORTEX AFTER TRANSIENT BILATERAL COMMON CAROTID ARTERY OCCLUSION AND REPERFUSION Serra MP#, Carta G#, Murru E, Boi M, Manca C, Lai Y, Cabboi M, Carta A, Banni S* and Quartu M* | Department of Biomedical Sciences, University of Cagliari, Italy #equal contribution; *co-seniorship

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4475
    232
  • Glyphosate, AMPA and glyphosate-based herbicide exposure leads to GFAP, PCNA and caspase-3 increased immunoreactive area on male offspring rat hypothalamus

    Ewing Duque-Díaz, Hernán Hurtado Giraldo, Linda P. Rocha-Muñoz, Rafael Coveñas
    13-10-2022
    https://doi.org/10.4081/ejh.2022.3428
    1601
    HTML: 68
    PDF: 760
  • Organotypic spinal cord cultures: An in vitro 3D model to preliminary screen treatments for spinal muscular atrophy

    Marina Boido, Elena De Amicis, Katia Mareschi, Franca Fagioli, Alessandro Vercelli
    04-11-2021
    https://doi.org/10.4081/ejh.2021.3294
    2123
    PDF: 836
    HTML: 24
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Vol. 70 No. 1 (2026)
Low ozone concentrations promote in vitro preservation of explanted articular cartilage: an ultrastructural study
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26 January 2026
Vol. 70 No. 1 (2026)
Overexpression of GPER1 suppressed esophageal carcinoma growth via activating cAMP pathway
Hongmei Yin et al.
26 January 2026

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European Journal of Histochemistry

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