17th International Conference of Histochemistry and Cytochemistry, 2025

All Items

• P72 | A SWAB NEGATIVE PATIENT AFTER SARS-COV-2 INFECTION DISPLAYS INCREASE OF VEGF AND FIBRONECTIN ASSOCIATED WITH ALTERATIONS OF INTERCELLULAR JUNCTIONS C. Simioni¹, J.M. Sanz², R. Gafà³, G. Cenacchi⁴, S. Occhionorelli³, R. Rizzo⁵, D. Bortolotti⁵, A. Passaro³, L.M. Neri³ | ¹Department of Life Sciences and Biotechnology, University of Ferrara, Italy; ²Department of Chemical, Pharmaceutical and Agricultural, Sciences, University of Ferrara, Italy; ³Department of Translational Medicine, University of Ferrara, Italy; ⁴Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum University of Bologna, Italy; ⁵Department of Environmental and Prevention Sciences, University of Ferrara, Italy

  https://doi.org/10.4081/ejh.2025.4397

  225

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• P40 | VOLUME ELECTRON MICROSCOPY REVEALS SPECIFIC FEATURES OF MITOTIC CELLS IN THE PINEAL ORGAN OF THE DOMESTIC TURKEY B. Lewczuk, N. Szyryńska, M. Prusik | Department of Histology and Embryology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Poland

  https://doi.org/10.4081/ejh.2025.4362

  151

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• P07 | DISRUPTED GUT-VASCULAR BARRIER AND INFLAMMATORY REMODELING IN MNGIE: A SPATIAL TRANSCRIPTOMIC AND HISTOLOGICAL STUDY S. Blando¹, E. Boschetti¹, I. Neri¹, L. Caporali², C. Fiorini², D. Ormanbekova², C. Malagelada³, I. Rusciano¹, V. Carelli², R. De Giorgio⁴, L. Manzoli¹, S. Ratti¹ | ¹Center of Clinical Surgical Molecular and Experimental Anatomy Alma Mater Studiorum, University of Bologna, Italy; ²IRCCS Institute of Neurological Sciences of Bologna, Neurogenetics Program, Bologna, Italy; ³Departament de Medicina, Universitat Autonoma de Barcelona, Barcelona, Spain; ⁴Department of Translational Medicine, University of Ferrara, Ferrara, Italy

  https://doi.org/10.4081/ejh.2025.4327

  138

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• THE EFFECT OF MUTANT HUNTINGTIN ON CLEAVAGE OF CREST BY CALPAIN-2 AND ITS CYTOTOXITY Y. Zhang, T. Peng, H. Li | Department of Histology and Embryology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China

  https://doi.org/10.4081/ejh.2025.4292

  146

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• P73 | ANALYSIS OF SAPK/JNK PATHWAY IN DOXORUBICIN INDUCED ADIPOSE-DERIVED STEM CELL CYTOTOXICITY A. Skubis-Sikora, B. Sikora, K. Pogoda-Mieszczak, E. Bogunia, P. Czekaj | Department of Cytophysiology, Chair of Histology and Embryology, Faculty of Medical Sciences in Katowice, Medical University of Silesia in Katowice, Poland

  https://doi.org/10.4081/ejh.2025.4398

  224

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• P41 | INVOLVEMENT OF THE DOLPHIN’S MELON IN IMMUNE FUNCTION G.P. Lombardo¹, A. Miller², L. Spiccia¹, V. Natale¹, F. Pellicanò¹, G. Squadrito¹, E. R. Lauriano¹ | ¹Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina; ²Department of Veterinary Sciences, University of Messina, Messina, Italy

  https://doi.org/10.4081/ejh.2025.4363

  169

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• P08 | COMBINED EFFECTS OF NONYLPHENOL AND STEROID HORMONES ON HUMAN PROSTATE CELL LINE S. Boccia¹, A. Mileo², F. Carrella³, R. Sciarrillo⁴, A. Capaldo¹, M. De Falco⁵ | ¹Dept. of Biology, University Federico II of Naples, Naples, Italy; ²Dept. of Medicine and Health Sciences, University of Molise, Campobasso, Italy; ³Dept. of Science and Technologies, University of Sannio, Benevento, Italy; ⁴Dept. of Science and Technologies, University of Sannio, Benevento, Italy; ⁵Dept. of Biology, University Federico II of Naples,; National Institute of Biostructures and Biosystems (INBB), Rome, Italy

  https://doi.org/10.4081/ejh.2025.4328

  151

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• HACAT CELLS AS A 2D EXPERIMENTAL DIFFERENTIATING MODEL TO ANALYZE THE EARLY BIOLOGICAL EFFECTS INDUCED BY A PSORIATIC PROINFLAMMATORY MICROENVIRONMENT: CELL PROLIFERATION, DIFFERENTIATION AND FERROPTOSIS F. Riva¹, S. Recalcati², E. Gammella², D. Daluiso¹, F. Prignano³, E. Donetti² | ¹Dept. Public Health, Experimental and Forensic Medicine; Histology and Embryology Unit, University of Pavia, Pavia, Italy; ²Dept. Biomedical Sciences for Health, University of Milan, Milan, Italy; ³Dept. Health Sciences, Section of Dermatology, University of Florence, Florence, Italy

  https://doi.org/10.4081/ejh.2025.4293

  158

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• P74 | EXPRESSION OF PISCIDIN, TLR-4, ERK2 AND P-P38 MAPK IN THE ZEBRAFISH GUT EXPOSED TO PCB-126 AND POSSIBLE PROTECTIVE EFFECTS OF GINESTEIN L. Spiccia¹, A. Miller², G.P. Lombardo¹, V. Natale¹, F. Pellicanò¹, S. Marino¹, A. Nunnari¹, A. Migliorato³, E.R. Laurian¹ | ¹Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina, Italy; ²Department of Veterinary Sciences, University of Messina, Messina, Italy; ³Department of Biomedical and Dental Sciences and Morphofunctional Images, University of Messina, Messina, Italy

  https://doi.org/10.4081/ejh.2025.4399

  208

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• P42 | PANCREATIC CANCER STEM CELLS AND FUNCTIONAL CHARACTERIZATION OF MIR-216A-5P G. Fenu¹, C.G. Lison², F. Etzi³, A. Pisano³, C. Farace³, A. Sabalic³, D. Tutedde³, J.A. Marchal⁴, R. Madeddu⁵ | ¹Department of Biomedical Science, University of Sassari, 07100 Sassari, Italy; ²Instituto de Investigación Biosanitaria ibs.GRANADA, University Hospitals of Granada-University of Granada, Granada, Spain; ³Department of Biomedical Science, University of Sassari, Sassari, Italy; ⁴Instituto de Investigación Biosanitaria ibs. GRANADA, University Hospitals of Granada-University of Granada, Granada, Spain; ⁵Department of Biomedical Science, University of Sassari, Sassari, Italy

  https://doi.org/10.4081/ejh.2025.4364

  151

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• P09 | EFFECTS OF NUTLIN-3A ACTIVITY ON 2D AND 3D RETINOBLASTOMA MODELS F. Bompan¹, R. Foschi², A. Dipinto³, F. Casciano², G. Lodi⁴, A. Sanvido⁵, P. Severi⁴, L. Giari¹, L. C. Cosenza⁵, R. Voltan², A. Romani⁴ | ¹Department of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy; ²Department of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy; LTTA Centre, University of Ferrara, Ferrara, Italy; ³Department of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy; ⁴Department of Translational Medicine, University of Ferrara, Ferrara, Italy; LTTA Centre, University of Ferrara, Ferrara, Italy; ⁵Department of Translational Medicine, University of Ferrara, Ferrara, Italy

  https://doi.org/10.4081/ejh.2025.4329

  158

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• FROM CLOUD TO BEDSIDE C. Tacchetti^1,2 | ¹Medical School & S.RACE (San-Raffaele Artificial Intelligence Center);Vita-Salute University San Raffaele, Milan, Italy; ²Experimental Imaging Center, IRCCS Hospital San Raffaele, Milan, Italy

  https://doi.org/10.4081/ejh.2025.4294

  156

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• P75 | MICROBIOTA-GUT-BRAIN AXIS IN AN AUTISM SPECTRUM DISORDER ANIMAL MODEL F. Sulas¹, G. Cominelli¹, G. Favero^1,2, D. Pinto^2,3, F. Rinaldi^2,3, R. Rezzani^1,2,4 | ¹Anatomy and Physiopathology Division, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy; ²Interdepartmental University Center of Research Adaption and Regeneration of Tissues and Organs (ARTO), University of Brescia, Brescia, Italy; ³Human Microbiome Advanced Project Institute, Milan, Italy; ⁴Italian Society for the Study of Orofacial Pain (Società Italiana Studio Dolore Orofacciale - SISDO), Brescia, Italy

  https://doi.org/10.4081/ejh.2025.4400

  250

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• P43 | NEW INSIGHTS IN THE ACTIVATION OF FERROPTOSIS PROCESS DURING LIVER FIBROSIS R. Mancinelli¹, S. Leone¹, A. Casini¹, R. Vaccaro¹, M. Tagliafierro¹, F.M. Bassi¹, E. Bocci¹, S. Vitale¹, A. Franchitto², L. Pannarale¹, P. Onori¹, E. Gaudio¹ | ¹Department of Anatomical, Histological, Forensic Medicine and Orthopaedics Sciences, Sapienza University of Rome, Italy; ²Division of Health Sciences, Department of Movement, Human and Health Sciences, University of Rome Foro Italico, Italy

  https://doi.org/10.4081/ejh.2025.4365

  175

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• P10 | ELECTRON MICROSCOPY-ADAPTED PHTHALOCYANINE AND VON KOSSA HISTOCHEMISTRY: A POWERFUL TOOL TO STUDY AORTIC VALVE CALCIFICATION IN AD HOC MODELS AND ACTUAL DISEASE A. Bonetti, M. Contin, M. Marchini, F. Ortolani | Department of Medicine, University of Udine, Udine, Italy

  https://doi.org/10.4081/ejh.2025.4330

  143

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• USE OF HIGH-DEFINITION IMAGING FLOW CYTOMETRY AND A.I. TO ENUMERATE AND CHARACTERISE CIRCULATING TUMOUR CELLS S. Saravi¹, S. Panfilov², E. Karteris² | ¹College of Health, Medicine and Life Sciences, Brunel University of London, UK; ²College of Health, Medicine and Life Sciences, Brunel University of London, UK

  https://doi.org/10.4081/ejh.2025.4295

  146

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• P76 | PERICAPILLARY SPACES IN THE SHEEP PINEAL GLAND – 2D AND 3D ANALYSIS N. Szyrynska, B. Lewczuk | Department of Histology and Embryology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Poland

  https://doi.org/10.4081/ejh.2025.4402

  264

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• P44 | CROSSTALK AMONG NEURONS, MUSCLE AND BONE: HUMAN NEUROMUSCULAR JUNCTION ON A CHIP M. Gatti^1,2, F. Beretti², M. Malenchini², M. Y. Follo¹, F. Mancarella³, F. Bonafè³, F. Gherardini⁴, T. Maraldi² | ¹Department of Biomedical and Neuromotor Science, Cellular Signalling Laboratory, University of Bologna, Italy; ²Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy; ³Istituto per lo Studio dei Materiali Nanostrutturati (ISMN), National Research Council (CNR), Bologna, Italy; ⁴Department of Engineering “Enzo Ferrari”, University of Modena and Reggio Emilia, Modena, Italy

  https://doi.org/10.4081/ejh.2025.4366

  137

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• P11 | DOMINO TRANSPLANTATION IN MNGIE: IS THE LIVER A SUITABLE GRAFT? E. Boschetti¹, I. Neri¹, S. Blando¹, C. Malagelada², L. Caporali³, R. D’Angelo⁴, R. Rinaldi⁴, S. Mongiorgi¹, V. Carelli³, R. De Giorgio⁵, L. Manzoli¹, S. Ratti¹ | ¹Center of Clinical Surgical Molecular and Experimental Anatomy Alma Mater Studiorum – University of Bologna, Italy; ²Digestive System Research Unit, University Hospital Vall d’Hebron; Barcelona, Spain; ³IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy; ⁴IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; ⁵Department of Translational Medicine, University of Ferrara, Ferrara, Italy

  https://doi.org/10.4081/ejh.2025.4331

  166

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• SUMOYLATION AS AN EARLY ADAPTIVE MECHANISM IN THE PROTEOMIC RESPONSE OF HUMAN GERM CELLS TO SIMULATED MICROGRAVITY A. Di Pauli¹, G. Ricci², M. Crescenzi³, M. A. Mariggiò⁴, C. Morabito⁴, L. Gesualdi¹, M. Berardini¹, F. Ferranti⁵, M. Signore⁶, A. Catizone¹ | ¹Department of Anatomy, Histology, Forensic-Medicine and Orthopedics, Section of Histology and Embryology, «Sapienza» University, Rome, Italy; ²Department of Experimental Medicine, University «Luigi Vanvitelli», Naples, Italy; ³Core Facilities, Italian National Institute of Health, Rome, Italy; ⁴Department of Neuroscience, Imaging and Clinical Sciences CAST, «G. d’Annunzio» University, Chieti, Italy; ⁵Human Spaceflight and Scientific Research Unit, Italian Space Agency, Rome, Italy; ⁶RPPA unit, Proteomics, Italian National Institute of Health, Rome, Italy

  https://doi.org/10.4081/ejh.2025.4296

  167

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• P77 | MEMBRANE SKELETAL PROTEIN, MEMBRANE PALMITOYLATED PROTEIN 6 (MPP6), IN MOUSE CEREBRAL SYNAPSES N. Terada¹, Y. Saitoh², S. Motofuji³, A. Kamijo⁴, T. Suzuki⁵, T. Yoshizawa⁶, T. Sakamoto⁷, K. Kametani⁸ | ¹Health Science Division, Shinshu University Graduate School of Medicine, Science and Technology, Japan; ²Center for Medical Education, Teikyo University of Science, Japan; ³Division of Biosciences, Teikyo University of Science Graduate School of Science & Engineering, Japan; ⁴Division of Basic & Clinical Medicine, Nagano College of Nursing, Japan; ⁵Department of Molecular and Cellular Physiology, Shinshu University Academic Assembly Institute of Medicine, Japan; ⁶Division of Animal Research, Research Center for Advanced Science and Technology, Shinshu University, Japan; ⁷Department of Cancer Biology, Institute of Biomedical Science, Kansai Medical University, Japan; ⁸Health Science Division, Shinshu University Graduate School of Medicine, Science and Technology, Japan

  https://doi.org/10.4081/ejh.2025.4403

  156

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• P45 | TARGETING PRELAMIN A PROCESSING TO SENSITIZE GLIOBLASTOMA CELLS TO OXIDATIVE STRESS M.V. Marvi¹, C. Evangelisti¹, I. Rusciano¹, I. Neri¹, L.I. Cocco¹, L. Manzoli¹, C. Capanni², S. Ratti¹ | ¹Cellular Signalling Laboratory, Anatomy Center, Department of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum-University of Bologna, Bologna, Italy; ²CNR Institute of Molecular Genetics «Luigi Luca Cavalli-Sforza», Unit of Bologna, Bologna, Italy / IRCCS Rizzoli Orthopedi, Institute, Bologna, Italy

  https://doi.org/10.4081/ejh.2025.4367

  174

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• P12 | VISUALIZING NUCLEAR ARCHITECTURE DURING MAMMAL ERYTHROPOIESIS C. Casali, M. Cavallo, S. Bellei, A. Diaf, L. Giulini, D. Tunesi, G. Milanesi, M. Biggiogera | Department of Biology and Biotechnology “L. Spallanzani”, University of Pavia, Pavia, Italy

  https://doi.org/10.4081/ejh.2025.4332

  161

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• FROM PIXELS TO DIAGNOSIS: A DEEP LEARNING FRAMEWORK FOR HISTOPATHOLOGICAL IMAGE ANALYSIS IN CANINE TESTICULAR PATHOLOGY L. Riccio¹, E. Formisano², M. De Falco³, S. Balsamo³, P. Formisano⁴, E. Di Napoli¹, G. Piegari¹, O. Paciello¹, L. Rosati³ | ¹Department of Veterinary Medicine and Animal Production, University of Naples “Federico II”, Naples, Italy; ²Department of Cognitive Neuroscience, Faculty of Psychology, Universiteit Maastricht, Postbus 616, The Netherlands; ³Department of Biology, University of Naples Federico II, Naples, Italy; ⁴Department of Translational Medicine, University Federico II, Naples, Italy

  https://doi.org/10.4081/ejh.2025.4297

  143

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• P78 | THE ROLE OF EXTRACELLULAR VESICLES DERIVED FROM MESENCHYMAL STROMAL CELLS IN MYOFIBER REGENERATION A. Longhin¹, V. Gatta², G. Teti², C. Sassoli³, F. Chellini³, A. Tani³, M. Parigi³, R. Garella³, F. Palmieri³, R. Squecco³, M. Mattioli Belmonte⁴, C. Licini⁴, A. La Contana⁴, S. Zecchi Orlandini³, M. Falconi¹ | ¹Dep. Medical and Surgical Sciences, University of Bologna, Bologna, Italy; ²Dep. Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy; ³Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; ⁴Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Italy

  https://doi.org/10.4081/ejh.2025.4404

  192

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• P46 | ANALYSIS OF AQUAPORIN-2 MUTANT MICE T. Matsuzaki¹, H. Yamamoto¹, K. Sasaki², H. Kogo¹, A. Iizuka-Kogo¹, M. Ikezawa¹, Y. Tajika¹ | ¹Dept. of Anatomy and Cell Biology, Graduate School of Medicine, Gunma University, Maebashi, Japan; ²Bioresource Center, Graduate School of Medicine, Gunma University, Maebashi; Faculty of Bioresources and Environmental Science, Ishikawa Prefectural University, Nonoichi, Japan

  https://doi.org/10.4081/ejh.2025.4368

  220

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• P13 | MORPHO-FUNCTIONAL DIFFERENCES IN THE GUT OF AGED MICE WITH THE POSSIBLE EFFECTS OF ANTI-INFLAMMATORY TREATMENTS A. Casini¹, S. Leone¹, R. Mancinelli¹, R. Vaccaro¹, M. Catalano², G. D’Alessandro², A. Rinaldi², A. Reccagni², G. Vivacqua³, A. Franchitto⁴, P. Onori¹, C. Limatola², E. Gaudio¹ | ¹Department of Anatomical, Histological, Forensic Medicine and Orthopaedics Sciences, Sapienza University of Rome, Italy; ²Department of Physiology and Pharmacology, Sapienza University of Rome, Italy; ³Department of Medicine and Surgery, University Campus BioMedico of Rome, Italy; ⁴Department of Movement, Human and Health Sciences, Division of Health Sciences, University of Rome «Foro Italico», Rome,Italy

  https://doi.org/10.4081/ejh.2025.4333

  138

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• THE MYSTERY OF INTERMEDIATE FILAMENTS: STRUCTURAL PERSPECTIVE O. Medalia | Deparment of Biochemistry, University of Zurich, Switzerland

  https://doi.org/10.4081/ejh.2025.4298

  136

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• P79 | AN INNOVATIVE FUNCTIONAL COOKIE MODULATES THE MUCOSA AND MYENTERIC PLEXUS IN THE GUT OF 3xTg-AD MOUSE MODEL OF ALZHEIMER’S DISEASE V. Bellitto¹, F. Grasselli¹, L. Lucernoni¹, I. Martinelli², E. Vittadini¹, A.M. Eleuteri¹, L. Bonfili¹, S.K. Tayebati², D. Tomassoni¹ | ¹School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy; ²School of Medicinal Sciences and Health Products, University of Camerino, Camerino, Italy

  https://doi.org/10.4081/ejh.2025.4405

  211

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• P47 | ASSESSMENT OF THE ANTI-INFLAMMATORY AND ANTIFIBROTIC EFFECTS OF HUMAN AMNIOTIC EPITHELIAL CELLS AFTER THEIR INTRATRACHEAL ADMINISTRATION IN A MOUSE MODEL OF BLEOMYCIN-INDUCED PULMONARY FIBROSIS E. Kolanko, A. Mazurski, A. Prusek, E. Bogunia, M. Hermyt, P. Czekaj | Department of Cytophysiology, Medical University of Silesia, Katowice, Poland

  https://doi.org/10.4081/ejh.2025.4369

  238

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• P14 | THE ROLE OF CHROMATIN REORGANIZATION IN HYPOXIA ADAPTATION M. Cavallo¹, C. Casali¹, L. Giulini¹, A. Dia¹, D. Tunesi¹, G. Milanesi¹, G. Mazzini², M. Biggiogera¹ | ¹Department of Biology and Biotechnology “L. Spallanzani”, University of Pavia, Pavia; Italy; ²Institute of Molecular Genetics, National Research Council (IGMCNR), Pavia, Italy

  https://doi.org/10.4081/ejh.2025.4334

  154

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• DOMAINS AND SIGNALLING PATHWAYS IN THE NUCLEUS L. Cocco | Department of Biomedical & Neuromotor Sciences, University of Bologna Medical School, Bologna. Italy

  https://doi.org/10.4081/ejh.2025.4299

  151

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• P80 | MITOCHONDRIA-LYSOSOME INTERACTIONS: EMERGING PLAYERS IN GLIOMA L. Zeppa¹, M.B. Morelli², C. Aguzzi², M. Giangrossi², M. Nabissi², G. Cameli², G. Santoni², S.K. Tayebati², V. Bellitto¹, D. Tomassoni¹, C. Amantini¹ | ¹School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy; ²School of Pharmacy, University of Camerino, Camerino, Italy

  https://doi.org/10.4081/ejh.2025.4406

  252

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• P48 | NEW STRATEGIES TO IMPROVE THE RESPONSE OF AML CELLS TO TARGETED THERAPIES BY OVERCOMING THE PROTECTIVE EFFECT OF THE BONE MARROW MESENCHYMAL STEM CELLS G. Mazzanti¹, F. Liccardo², L. Pace¹, M. Marcotulli³, L. Lafrate³, G. Cidonio³, T. Ottone⁴, S. Travaglini⁴, M.T. Voso⁴, V. Fulci⁵, M. Sampaolesi¹, F. Fazi¹, S. Masciarelli¹ | ¹Department of Anatomical, Histological, Forensic Medicine and Orthopedics Sciences and Medical Embryology, Section of Histology Sapienza University of Rome, Rome, Italy; ²Centre de Recherches en Cancérologie de Toulouse, Inserm/ U1037, Université de Toulouse, Toulouse, France; ³Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, Rome, Italy; ⁴Department of Biomedicine and Prevention, University of Tor Vergata, Rome, Italy; ⁵Department of Molecular Medicine, Sapienza, University of Rome, Rome, Italy

  https://doi.org/10.4081/ejh.2025.4370

  207

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• P15 | PHB/JAK/H3Y41PH AXIS REGULATES MEIOTIC RECOMBINATION IN SPERMATOGENESIS H. Chen¹, L. Zhang¹, W. Tan-Tai¹, M. Liu², H. Shi³, W. O⁴, P.A. Martin-DeLeon⁵ | ¹Department of Anatomy, Histology & Embryology, Shanghai Medical College, Fudan University, Shanghai, China; ²State Key Laboratory of Molecular Biology, Chinese Academy of Sciences-University of Chinese Academy of Sciences, Shanghai, China; ³NHC Key Lab of Reproduction Regulation, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai, China; ⁴School of Biomedical Sciences, The University of Hong Kong, Hong Kong SAR, China; ⁵Department of Biological Sciences, University of Delaware, Newark, USA

  https://doi.org/10.4081/ejh.2025.4335

  154

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• LIPID DROPLETS AND NUCLEAR LIPID DYNAMICS T. Fujimoto | Research Institute for Diseases of Old Age, Juntendo University Graduate School of Medicine, Tokyo, Japan.

  https://doi.org/10.4081/ejh.2025.4300

  148

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• LEVERAGING ORGANOID TECHNOLOGIES TO CHARACTERIZE DYNAMIC TUMOR CELL STATES DRIVING TREATMENT RESISTANCE IN PANCREATIC CANCER A. Papargyriou^1-6, M. Najajreh^1-4, D.P. Cook⁷, C.H. Maurer^1,2, S. Bärthel⁸, P. Putze⁸, H.A. Messal⁹, S.K. Ravichandran^1-3, T. Richter¹⁰, M. Knolle¹¹, T. Metzler¹², A.R. Shastri^1,2,3, R. Öllinger¹³, J. Jasper^1,2,3, L. Schmidleitner^1,2,3, C.Schneeweis⁸, H. Ishikawa-Ankerhold¹⁴, T. Engleitner¹³, S. Dobiasch¹⁵, I. Heid, M.D. Luecken¹⁶, K. Steiger¹², G. Kaissis¹¹, J. Van Rheenen⁹, F.J. Theis¹⁰, D. Saur⁸, R. Rad¹³, M. Reichert^{1,2,3,4,5,17,18} | ¹Translational Pancreatic Cancer Research Center, Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar, Technical University of Munich, Germany; ²Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar, Technical University of Munich, Germany; ³Center for Functional Protein Assemblies, Technical University of Munich, Garching, Germany; ⁴Center for Organoid Systems (COS), Technical University of Munich, Garching, Germany; ⁵Bavarian Cancer Research Center (BZKF), Munich, Germany; ⁶Institute of Stem Cell Research, Helmholtz Center Munich, Neuherberg, Germany; ⁷University of Ottawa, Faculty of Medicine, Department of Cellular and Molecular Medicine, Ottawa, ON, Canada; ⁸Chair for Translational Cancer Research and Institute of Experimental Cancer Therapy, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Germany; ⁹Division of Molecular Pathology, Oncode Institute, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX, Amsterdam, The Netherlands. ¹⁰Institute of Computational Biology, Helmholtz Center Munich, Neuherberg, Germany; ¹¹Institute of Diagnostic and Interventional Radiology, Klinikum rechts der Isar München, Technical University of Munich, Germany; ¹²Comparative Experimental Pathology, Institut für Allgemeine Pathologie und Pathologische Anatomie, School of Medicine, Technical University of Munich, Germany; ¹³Institute of Molecular Oncology and Functional Genomics, School of Medicine, Technical University of Munich, Germany; ¹⁴Department of Medicine I, University Hospital of the LudwigMaximilians-University Munich, Germany; ¹⁵Department of Radiation Oncology, Technical University of Munich, Germany; ¹⁶Institute of Lung Health and Immunity (LHI), Helmholtz Munich, Comprehensive Pneumology Center (CPC-M), Germany; Member of the German Center for Lung Research (DZL); ¹⁷German Cancer Consortium (DKTK), Munich, Germany; ¹⁸Munich Institute of Biomedical Engineering (MIBE), Technical University of Munich, Germany

  https://doi.org/10.4081/ejh.2025.4289

  235

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