17th International Conference of Histochemistry and Cytochemistry, 2025

All Items

• PATHOMICS – A NOVEL OMICS APPROACH FOR HISTOPATHOLOGY P. Boor^1,2 | ¹Institute of Pathology, RWTH Aachen University Hospital, Aachen, Germany; Electron Microscopy Facility, RWTH Aachen University Hospital, Aachen, Germany; ²Division of Nephrology and Immunology, RWTH Aachen University Hospital, Aachen, Germany

  https://doi.org/10.4081/ejh.2025.4284

  254

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• P66 | FROM INNERVATION TO STEROIDOGENIC DEFECT: IMPLICATIONS OF CGRP IN THE PATHOPHYSIOLOGY OF POLYCYSTIC OVARY SYNDROME L. Sallicandro¹, R. Gentile², B. Filová³, S. Polakovičová³, A. Biagini¹, F. Ballarino⁴, D. Del Bianco⁴, I. Varga⁵, A. Malvasi⁶, B. Fioretti² | ¹Department of Medicine and Surgery, University of Perugia, Perugia, Italy; ²Department of Chemistry, Biology and Biotechnologies, University of Perugia, Italy; ³Department of Histology and Embriology, Comenius University, Bratislava, Slovakia; ⁴Department of Chemistry, Biology and Biotechnologies, University of Perugia, Italy; ⁵Department of Histology and Embriology, Comenius University, Bratislava, Slovakia; ⁶Department of Biomedical Sciences and Human Oncology, Obstetrics and Gynecology Unit, University of Bari Aldo Moro, Bari, Italy

  https://doi.org/10.4081/ejh.2025.4391

  437

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• P33 | IMPACT OF CYCLIN C EXPRESSION ON THE AGGRESSIVENESS OF A549 NON-SMALL CELL LUNG CANCER CELLS V. Havryliuk | Department of Histology and Embryology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Poland

  https://doi.org/10.4081/ejh.2025.4353

  252

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• P01 | PUTATIVE EFFECTS OF THE HYDROGEL-STEM CELL-MELATONIN COMBINATION WITH OR WITHOUT A SCAFFOLD TO TREAT THIOACETAMIDE-INDUCED LIVER DEGENERATION IN RAT G. Ozgun¹, D. Yucel², M. Kolgazi³, S. Ozer⁴, N. Tozun⁵, S. Arbak⁶ | ¹Dept of Medical Biotechnology, Institute of health sciences, Acibadem Univ, Istanbul, Türkiye; ²Dept. of Histology and Embryology, School of Medicine, Acibadem Univ, Istanbul, Türkiye; ³Dept. of Physiology, School of Medicine, Acibadem Univ., Istanbul, Türkiye; ⁴Animal Application and Research Center, Acibadem Univ. Istanbul, Türkiye; ⁵Dept. of Gastroenterology, School of Medicine, Acibadem Univ., Istanbul, Türkiye; ⁶Dept. of Histology and Embryology, School of Medicine, Acibadem Univ., Istanbul, Türkiye

  https://doi.org/10.4081/ejh.2025.4321

  256

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• ACCELERATING DISCOVERY TOGETHER: A COMMUNITY APPROACH TO ANTIBODY VALIDATION AND MULTIPLEXED IMAGING A. Radtke | Leica Microsystems

  https://doi.org/10.4081/ejh.2025.4285

  238

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• P67 | EMERGING ROLE OF NUCLEAR PHOSPHOLIPASE C BETA 1 AS POTENTIAL BIOMARKER IN LUNG CANCER S. Salucci¹, I. Versari¹, S. Burattini², D. Montecchio³, I. Faenza¹ | ¹Department of Biomedical and NeuroMotor Sciences, University of Bologna, Bologna, Italy; ²Department of Biomolecular Sciences, University of Urbino Carlo Bo, Urbino, Italy; ³Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy

  https://doi.org/10.4081/ejh.2025.4392

  389

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• P34 | ADJUDIN-INDUCED MODEL IN RATS REVEALS HIPPO SIGNALING PATHWAY ACTIVITY IN THE TESTIS İ. İnanç¹, O. Bender², A. Atalay², E. Erdemli¹ | ¹Ankara University, Faculty of Medicine, Department of Histology and Embryology, Ankara, Türkiye; ²Ankara University, Biotechnology Institute, Ankara, Türkiye

  https://doi.org/10.4081/ejh.2025.4354

  407

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• P02 | THE C-C CHEMOKINE-RECEPTOR 2 (CCR2)/CCL2 AXIS PARTICIPATE IN PLATELET FUNCTION IN MYELOFIBROSIS F. Arciprete¹, V. Velardi¹, G. Pozzi², C. Carubbi³, S. Cortellazzi³, A.M. Vannucchi⁴, M. Vitale⁵, R.A. Rana¹, G. Vivacqua¹, E. Masselli³, M. Zingariello¹ | ¹Unit of Microscopic and Ultrastructural Anatomy, University Campus Bio-Medico, Rome, Italy; ²Anatomy Unit, Department of Medicine and Surgery (DiMeC), University of Parma, Parma, Italy; ³Anatomy Unit, Department of Medicine and Surgery (DiMeC), University of Parma, Parma, Italy; ⁴Center Research and Innovation of Myeloproliferative Neoplasm, University Hospital Careggi, University of Florence, Florence, Italy; ⁵San Raffaele University, Milano, Italy

  https://doi.org/10.4081/ejh.2025.4322

  416

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• ANIMAL MODELS FOR LINEAGE TRACING IN (CELL) TRANSDIFFERENTIATION S. Cinti | Center for The Study of Obesity. Marche Polytechnic University, Ancona, Italy

  https://doi.org/10.4081/ejh.2025.4286

  220

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• P68 | EARLY EFFECTS OF MECHANOACUSTIC FOCUSED VIBRATION (MFV) ON PRIMARY HUMAN SATELLITE CELLS ISOLATED FROM YOUNG AND OLDER INDIVIDUALS S. Sancilio¹, G. Stati¹, E.S. Di Filippo², S. Fulle², R. Di Pietro¹ | ¹Department of Medicine and Aging Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy; ²Department of Neuroscience Imaging and Clinical Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy

  https://doi.org/10.4081/ejh.2025.4393

  332

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• P35 | EARLY LIFE STRESS CAN CAUSE CHANGES IN THE HIPPO SIGNALING PATHWAY IN RAT OVARIES İ. İnanç¹, E. Baysal¹, O. Bender², A. Atalay², E. Erdemli¹ | ¹Ankara University, Faculty of Medicine, Department of Histology and Embryology, Ankara, Türkiye; ²Ankara University, Biotechnology Institute, Ankara, Türkiye

  https://doi.org/10.4081/ejh.2025.4355

  221

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• P03 | THE ROLE OF FILAMIN A IN REGULATING BREAST CANCER CELL BEHAVIOR AND TUMOR MICROENVIRONMENT INTERACTIONS W. Arendt¹, P. Zawadka¹, M. Hałas-Wiśniewska¹, M. Gagat², M. Izdebska¹ | ¹ Department of Histology and Embryology, Faculty of Medicine, Ludwik Rydygier Collegium Medicum in Bydgoszcz Nicolaus Copernicus University in Toruń, Poland; ²Department of Histology and Embryology, Faculty of Medicine, Ludwik Rydygier Collegium Medicum in Bydgoszcz Nicolaus Copernicus University in Toruń; Faculty of Medicine, Collegium Medicum, Mazovian Academy in Płock, Poland

  https://doi.org/10.4081/ejh.2025.4323

  242

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• ANIMAL MODELS OF METASTATIC CANCER - ADVANCED IMAGE ANALYSIS FOR DISSECTION OF DRIVING SIGNALING PATHWAYS S. Alberti | University of Messina, Messina, Italy

  https://doi.org/10.4081/ejh.2025.4287

  251

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• P69 | MICROPLASTICS AND ATHEROSCLEROSIS: EVIDENCE OF MICROPLASTICS IN CAROTID ATHEROSCLEROTIC PLAQUES R. Sciarrillo¹, V. Gallicchio¹, A. Lallo¹, F. Carrella¹, D. Barbarisi², A. Falzarano¹, M. De Falco³, F. Flora², A. Peluso², S. Piccolo², L. Flora² | ¹Department of Science and Technologies, University of Sannio, Italy; ²Vascular Surgery, Hospital of National Importance San Giuseppe Moscati, Italy; ³Department of Biology, University of Naples, Italy

  https://doi.org/10.4081/ejh.2025.4394

  491

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• P36 | BIOLOGICAL ROLE OF DNA G-QUADRUPLEX DURING LIVER REGENERATION AFTER PARTIAL HEPATECTOMY T. Ishizuka, K. M. Aung, T. Kubota, B. Lkham-Erdene, K. Kai, Y. Hishikawa | Department of Anatomy, Histochemistry and Cell Biology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan

  https://doi.org/10.4081/ejh.2025.4358

  248

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• P04 | CYTOCHEMICAL AND BIOLOGICAL EFFECT OF BIORESONANCE IN IRRITABLE BOWEL SYNDROME G. Barassi¹, M. Panunzio², P.E. Gallenga¹ | ¹Center for Physiotherapy, Rehabilitation and Re-Education (Ce.Fi.R.R.), Venue “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy; ²Responsible Research Hospital, Campobasso, Italy

  https://doi.org/10.4081/ejh.2025.4324

  312

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• THE USE OF BIOMIMETIC 2D AND 3D UROTHELIAL IN VITRO MODELS WITH MOLECULAR, MORPHOLOGICAL AND FUNCTIONAL CHARACTERISTICS OF NORMAL AND CANCEROUS BLADDER TISSUE AS AN ALTERNATIVE METHOD IN PRECLINICAL STUDIES M.E. Kreft¹, L. Tratnjek¹, A. Janev¹, N. Resnik¹, U. Cerkvenik¹, U. D. Jerman¹, G. Markovič¹, T.Ž. Ramuta¹, T. Višnjar¹, Ž. Sardoč¹, A.Punčuh¹, S. Kralj², M. Čemažar³, P. Veranič¹ |¹Institute of Cell Biology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia; ²Department for Materials Synthesis, Jožef Stefan Institute, Ljubljana, Slovenia; ³Institute of Oncology Ljubljana, Ljubljana, Slovenia

  https://doi.org/10.4081/ejh.2025.4288

  304

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• P70 | TRICHOSANTHIN TARGETS WNT/NF-KB PATHWAYS TO ATTENUATE PSORIATIC INFLAMMATION AND KERATINOCYTE HYPERPROLIFERATION K. Wang¹, W. Li¹, Z. Ying¹, C. Li², O. Sha¹ | ¹Department of Anatomy and Histology, School of Basic Medical Sciences, Shenzhen University Medical School, Shenzhen, China; ²Department of Anatomy, Shantou University Medical College, Shantou, China

  https://doi.org/10.4081/ejh.2025.4395

  407

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• P37 | THE ROLE OF ACTIN-BINDING PROTEINS IN ENDOMETRIOSIS W. Arendt¹, M. Hałas-Wiśniewska¹, M. Gagat², M. Izdebska¹ | ¹Department of Histology and Embryology, Faculty of Medicine, Nicolaus Copernicus University in Toruń, Collegium Medicum in Bydgoszcz, Poland; ²Department of Histology and Embryology, Faculty of Medicine, Nicolaus Copernicus University in Toruń, Collegium Medicum in Bydgoszcz, Poland; Faculty of Medicine, Collegium Medicum, Mazovian Academy in Płock, Poland

  https://doi.org/10.4081/ejh.2025.4359

  267

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• P05 | ENTERIC NERVOUS SYSTEM NEUROPLASTICITY IN COLON OF ANIMAL MODELS OF OBESITY V. Bellitto¹, I. Martinelli², G. Nittari², S.K. Tayebati², D. Tomassoni¹ | ¹School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy; ²School of Medicinal and Health Products Sciences, University of Camerino, Camerino, Italy

  https://doi.org/10.4081/ejh.2025.4325

  238

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• FROM BULK TO SELECTIVE: A JOURNEY THROUGH THE PHYSIOLOGICAL RELEVANCE OF AUTOPHAGY C. Settembre^1,2 | ¹ University of Naples Federico II, Naples, Italy; ²Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy

  https://doi.org/10.4081/ejh.2025.4290

  229

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• P71 | THE EXTRACELLULAR VESICLE POPULATIONS UNDERWENT ALTERATIONS SUBSEQUENT TO THE PRETREATMENT OF ADIPOSE-DERIVED STEM CELLS WITH MELATONIN RECEPTOR AGONIST B. Sikora, K. Pogoda-Mieszczak, E. Bogunia, A. Skubis-Sikora, P. Czekaj | Department of Cytophysiology, Faculty of Medical Sciences in Katowice, Medical University of Silesia in Katowice, Poland

  https://doi.org/10.4081/ejh.2025.4396

  372

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• P38 | THE ROLE OF SPEXIN IN COLORECTAL CANCER J. Kiezun¹, J. Godlewski¹, M. Kiezun², M. Gudelska¹, K. Kisielewska¹, A. E. Kowalczyk¹, B. E. Krazinski¹ | ¹Department of Anatomy and Histology, School of Medicine, Collegium Medicum, University of Warmia and Mazury in Olsztyn, Poland; ²Department of Animal Anatomy and Physiology, Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, Poland

  https://doi.org/10.4081/ejh.2025.4360

  268

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• P06 | MICROGRAVITY-INDUCED CHANGES IN CYTOSKELETON STRUCTURE OF TCAM-2 CELLS M. Berardini¹, L. Gesualdi¹, A. Di Pauli¹, M. Signore², S. Broccolucci¹, F. Ferranti³, M. Bizzarri⁴, M. Tafani⁴, G. Ricci⁵, A. Catizone¹ | ¹Dept of Anatomy, Histology, Forensic-Medicine and Orthopedics,“Sapienza” University of Rome, Rome, Italy; ²RPPA Unit, Proteomics Area, Core Facilities, Istituto Superiore di Sanità, Rome, Italy; ³Human Spaceflight and Scientific Research Unit, Italian Space Agency, Rome, Italy; ⁴Dept of Experimental Medicine “Sapienza” University of Rome, Rome, Italy; ⁵Dept of Experimental Medicine, Università degli Studi della Campania “Luigi Vanvitelli”, Naples, Italy

  https://doi.org/10.4081/ejh.2025.4326

  263

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• ROLE OF MITOCHONDRIAL METABOLISM AND CONTACT SITES IN CANCER CELL DEATH AND SURVIVAL F. Severin, A. Ruzza, F. Vianello, E. Zaltron, I. Celotti, M. Scavezzon, S. Toffanin, C. Bastianello, L. Leanza | Department of Biology, University of Padova, Padova, Italy

  https://doi.org/10.4081/ejh.2025.4291

  311

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• P72 | A SWAB NEGATIVE PATIENT AFTER SARS-COV-2 INFECTION DISPLAYS INCREASE OF VEGF AND FIBRONECTIN ASSOCIATED WITH ALTERATIONS OF INTERCELLULAR JUNCTIONS C. Simioni¹, J.M. Sanz², R. Gafà³, G. Cenacchi⁴, S. Occhionorelli³, R. Rizzo⁵, D. Bortolotti⁵, A. Passaro³, L.M. Neri³ | ¹Department of Life Sciences and Biotechnology, University of Ferrara, Italy; ²Department of Chemical, Pharmaceutical and Agricultural, Sciences, University of Ferrara, Italy; ³Department of Translational Medicine, University of Ferrara, Italy; ⁴Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum University of Bologna, Italy; ⁵Department of Environmental and Prevention Sciences, University of Ferrara, Italy

  https://doi.org/10.4081/ejh.2025.4397

  377

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• P40 | VOLUME ELECTRON MICROSCOPY REVEALS SPECIFIC FEATURES OF MITOTIC CELLS IN THE PINEAL ORGAN OF THE DOMESTIC TURKEY B. Lewczuk, N. Szyryńska, M. Prusik | Department of Histology and Embryology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Poland

  https://doi.org/10.4081/ejh.2025.4362

  244

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• P07 | DISRUPTED GUT-VASCULAR BARRIER AND INFLAMMATORY REMODELING IN MNGIE: A SPATIAL TRANSCRIPTOMIC AND HISTOLOGICAL STUDY S. Blando¹, E. Boschetti¹, I. Neri¹, L. Caporali², C. Fiorini², D. Ormanbekova², C. Malagelada³, I. Rusciano¹, V. Carelli², R. De Giorgio⁴, L. Manzoli¹, S. Ratti¹ | ¹Center of Clinical Surgical Molecular and Experimental Anatomy Alma Mater Studiorum, University of Bologna, Italy; ²IRCCS Institute of Neurological Sciences of Bologna, Neurogenetics Program, Bologna, Italy; ³Departament de Medicina, Universitat Autonoma de Barcelona, Barcelona, Spain; ⁴Department of Translational Medicine, University of Ferrara, Ferrara, Italy

  https://doi.org/10.4081/ejh.2025.4327

  231

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• THE EFFECT OF MUTANT HUNTINGTIN ON CLEAVAGE OF CREST BY CALPAIN-2 AND ITS CYTOTOXITY Y. Zhang, T. Peng, H. Li | Department of Histology and Embryology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China

  https://doi.org/10.4081/ejh.2025.4292

  241

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• P73 | ANALYSIS OF SAPK/JNK PATHWAY IN DOXORUBICIN INDUCED ADIPOSE-DERIVED STEM CELL CYTOTOXICITY A. Skubis-Sikora, B. Sikora, K. Pogoda-Mieszczak, E. Bogunia, P. Czekaj | Department of Cytophysiology, Chair of Histology and Embryology, Faculty of Medical Sciences in Katowice, Medical University of Silesia in Katowice, Poland

  https://doi.org/10.4081/ejh.2025.4398

  368

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• P41 | INVOLVEMENT OF THE DOLPHIN’S MELON IN IMMUNE FUNCTION G.P. Lombardo¹, A. Miller², L. Spiccia¹, V. Natale¹, F. Pellicanò¹, G. Squadrito¹, E. R. Lauriano¹ | ¹Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina; ²Department of Veterinary Sciences, University of Messina, Messina, Italy

  https://doi.org/10.4081/ejh.2025.4363

  265

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• P08 | COMBINED EFFECTS OF NONYLPHENOL AND STEROID HORMONES ON HUMAN PROSTATE CELL LINE S. Boccia¹, A. Mileo², F. Carrella³, R. Sciarrillo⁴, A. Capaldo¹, M. De Falco⁵ | ¹Dept. of Biology, University Federico II of Naples, Naples, Italy; ²Dept. of Medicine and Health Sciences, University of Molise, Campobasso, Italy; ³Dept. of Science and Technologies, University of Sannio, Benevento, Italy; ⁴Dept. of Science and Technologies, University of Sannio, Benevento, Italy; ⁵Dept. of Biology, University Federico II of Naples,; National Institute of Biostructures and Biosystems (INBB), Rome, Italy

  https://doi.org/10.4081/ejh.2025.4328

  252

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• HACAT CELLS AS A 2D EXPERIMENTAL DIFFERENTIATING MODEL TO ANALYZE THE EARLY BIOLOGICAL EFFECTS INDUCED BY A PSORIATIC PROINFLAMMATORY MICROENVIRONMENT: CELL PROLIFERATION, DIFFERENTIATION AND FERROPTOSIS F. Riva¹, S. Recalcati², E. Gammella², D. Daluiso¹, F. Prignano³, E. Donetti² | ¹Dept. Public Health, Experimental and Forensic Medicine; Histology and Embryology Unit, University of Pavia, Pavia, Italy; ²Dept. Biomedical Sciences for Health, University of Milan, Milan, Italy; ³Dept. Health Sciences, Section of Dermatology, University of Florence, Florence, Italy

  https://doi.org/10.4081/ejh.2025.4293

  282

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• P74 | EXPRESSION OF PISCIDIN, TLR-4, ERK2 AND P-P38 MAPK IN THE ZEBRAFISH GUT EXPOSED TO PCB-126 AND POSSIBLE PROTECTIVE EFFECTS OF GINESTEIN L. Spiccia¹, A. Miller², G.P. Lombardo¹, V. Natale¹, F. Pellicanò¹, S. Marino¹, A. Nunnari¹, A. Migliorato³, E.R. Laurian¹ | ¹Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina, Italy; ²Department of Veterinary Sciences, University of Messina, Messina, Italy; ³Department of Biomedical and Dental Sciences and Morphofunctional Images, University of Messina, Messina, Italy

  https://doi.org/10.4081/ejh.2025.4399

  347

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• P42 | PANCREATIC CANCER STEM CELLS AND FUNCTIONAL CHARACTERIZATION OF MIR-216A-5P G. Fenu¹, C.G. Lison², F. Etzi³, A. Pisano³, C. Farace³, A. Sabalic³, D. Tutedde³, J.A. Marchal⁴, R. Madeddu⁵ | ¹Department of Biomedical Science, University of Sassari, 07100 Sassari, Italy; ²Instituto de Investigación Biosanitaria ibs.GRANADA, University Hospitals of Granada-University of Granada, Granada, Spain; ³Department of Biomedical Science, University of Sassari, Sassari, Italy; ⁴Instituto de Investigación Biosanitaria ibs. GRANADA, University Hospitals of Granada-University of Granada, Granada, Spain; ⁵Department of Biomedical Science, University of Sassari, Sassari, Italy

  https://doi.org/10.4081/ejh.2025.4364

  242

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• P09 | EFFECTS OF NUTLIN-3A ACTIVITY ON 2D AND 3D RETINOBLASTOMA MODELS F. Bompan¹, R. Foschi², A. Dipinto³, F. Casciano², G. Lodi⁴, A. Sanvido⁵, P. Severi⁴, L. Giari¹, L. C. Cosenza⁵, R. Voltan², A. Romani⁴ | ¹Department of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy; ²Department of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy; LTTA Centre, University of Ferrara, Ferrara, Italy; ³Department of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy; ⁴Department of Translational Medicine, University of Ferrara, Ferrara, Italy; LTTA Centre, University of Ferrara, Ferrara, Italy; ⁵Department of Translational Medicine, University of Ferrara, Ferrara, Italy

  https://doi.org/10.4081/ejh.2025.4329

  241

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• FROM CLOUD TO BEDSIDE C. Tacchetti^1,2 | ¹Medical School & S.RACE (San-Raffaele Artificial Intelligence Center);Vita-Salute University San Raffaele, Milan, Italy; ²Experimental Imaging Center, IRCCS Hospital San Raffaele, Milan, Italy

  https://doi.org/10.4081/ejh.2025.4294

  261

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