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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

1.9
Impact Factor 2025
3.7
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1.9
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3.7
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  • Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice

    Nana Bao, Min Zhang, Ming Tang, Ziyi Shen, Shenglin Wang, Guohui Jiang
    20-04-2026
    https://doi.org/10.4081/ejh.2026.4548
    774
    PDF: 442
    Raw data: 66
    HTML: 25
  • CCL18 promotes endometriosis by increasing endometrial cell migration and neuroangiogenesis

    Yangying Peng, Shaojie Ding, Ping Xu, Xueyan Zhang, Jianzhang Wang, Tiantian Li, Liyun Liao, Xinmei Zhang
    06-08-2024
    https://doi.org/10.4081/ejh.2024.4052
    1183
    PDF: 799
    HTML: 50
  • Impact of Histochemistry on biomedical research: looking through the articles published in a long-established histochemical journal

    C. Pellicciari
    30-12-2014
    https://doi.org/10.4081/ejh.2014.2474
    2512
    PDF: 730
    HTML: 827
  • Deletion of osteopontin in non-small cell lung cancer cells affects bone metabolism by regulating miR-34c/Notch1 axis: a clue to bone metastasis

    Jing Guo, Chang-Yong Tong, Jian-Guang Shi, Xin-Jian Li, Xue-Qin Chen
    26-07-2023
    https://doi.org/10.4081/ejh.2023.3631
    1509
    PDF: 852
    HTML: 37
  • Dipeptidylpeptidase-­IV, a key enzyme for the degradation of incretins and neuropeptides: activity and expression in the liver of lean and obese rats

    E. Tarantola, V. Bertone, G. Milanesi, E. Capelli, A. Ferrigno, D. Neri, M. Vairetti, S. Barni, I. Freitas
    e41
    08-10-2012
    https://doi.org/10.4081/ejh.2012.e41
    1855
    PDF: 936
    HTML: 1094
  • Differential antigen expression between human apocrine sweat glands and eccrine sweat glands

    Manxiu Cao, Lei Zhang, Jiaqi Chen, Cangyu Wang, Junhong Zhao, Xiang Liu, Yongjing Yan, Yue Tang, Zixiu Chen, Haihong Li
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3559
    2697
    PDF: 1133
    HTML: 69
  • Pre-treatment with galectin-1 attenuates lipopolysaccharide-induced myocarditis by regulating the Nrf2 pathway

    Liying Shen, Kongjie Lu, Zhenfeng Chen, Yingwei Zhu, Cong Zhang, Li Zhang
    07-12-2023
    https://doi.org/10.4081/ejh.2023.3816
    1313
    PDF: 782
    HTML: 44
  • Downregulation of S100 calcium-binding A4 (S100A4) ameliorates hepatic fibrosis via regulating Wnt/β-catenin signaling pathway

    Chixian Zhang, Kai Bai, Dexu Li
    14-04-2025
    https://doi.org/10.4081/ejh.2025.4186
    1560
    PDF: 561
    HTML: 42
  • The role of miR-143-3p/FNDC1 axis on the progression of non-small cell lung cancer

    Zhanshu Ma, Qi Gao, Wenjing Xin, Lei Wang, Yan Chen, Chang Su, Songyan Gao, Ruiling Sun
    03-05-2023
    https://doi.org/10.4081/ejh.2023.3577
    2199
    PDF: 666
    HTML: 40
  • Changes in subcellular localization of visfatin in human colorectal HCT-116 carcinoma cell line after cytochalasin B treatment

    R.J. Bułdak, M. Skonieczna, Ł. Bułdak, N. Matysiak, Ł. Mielańczyk, G. Wyrobiec, M. Kukla, M. Michalski, K. Żwirska-Korczala
    12-09-2014
    https://doi.org/10.4081/ejh.2014.2408
    2198
    PDF: 857
    HTML: 586
  • Tanshinone IIA attenuates hepatic stellate cell activation, oxidative stress, and liver fibrosis by inhibiting YAP signaling

    Dan Wang, Qingquan Tan, Qing Zheng, Yanling Ma, Li Feng
    17-06-2025
    https://doi.org/10.4081/ejh.2025.4218
    1798
    PDF: 695
    HTML: 40
  • Expression of the HPV18/E6 oncoprotein induces DNA damage

    Elva I. Cortés Gutiérrez, Catalina Garcí­a-Vielma, Adriana Aguilar-Lemarroy, Veronica Vallejo-Ruí­z, Patricia Piña-Sánchez, Pablo Zapata-Benavides, Jaime Gosalvez
    15-06-2017
    https://doi.org/10.4081/ejh.2017.2773
    2070
    PDF: 869
    HTML: 218
  • Developmental expression of inositol 1, 4, 5-trisphosphate receptor in the post-natal rat cochlea

    W.J. Liu, J. Yang
    21-04-2015
    https://doi.org/10.4081/ejh.2015.2486
    2400
    PDF: 838
    HTML: 1041
  • Ghrelin reduces cerebral ischemic injury in rats by reducing M1 microglia/macrophages

    Rong Tian, Gengsheng Mao
    12-01-2022
    https://doi.org/10.4081/ejh.2022.3350
    1910
    PDF: 1011
    HTML: 47
  • Erratum - Autophagic degradation of farnesylated prelamin A as a therapeutic approach to lamin-linked progeria

    V. Cenni, C. Capanni, M. Columbaro, M. Ortolani, M.R. D'Apice, G. Novelli, M. Fini, S. Marmiroli, E. Scarano, N.M. Maraldi, S. Squarzoni, S. Prencipe, G. Lattanzi
    e42
    19-12-2013
    https://doi.org/10.4081/ejh.2013.e42
    2624
    PDF: 665
    HTML: 191
  • Effects of piperlonguminine on lung injury in severe acute pancreatitis via the TLR4/NF-κB pathway

    Qian Hu, Ran Tao, Xiaoyun Hu, Haibo Wu, Jianjun Xu
    20-03-2023
    https://doi.org/10.4081/ejh.2023.3639
    1381
    PDF: 826
    HTML: 29
  • An improved method for preparation of mouse retinal cryosections

    Ling Li, Yongqiong Lin, Fang Yang, Tongdan Zou, Jialiang Yang, Houbin Zhang
    03-09-2020
    https://doi.org/10.4081/ejh.2020.3154
    2445
    PDF: 1464
    Supplementary: 204
    HTML: 667
  • Histochemistry in biology and medicine: a message from the citing journals

    Carlo Pellicciari
    23-12-2015
    https://doi.org/10.4081/ejh.2015.2610
    3322
    PDF: 932
    HTML: 904
  • Novel monoclonal antibodies against Pdx1 reveal feedback regulation of Pdx1 protein levels

    T. Galbo, I. L Pedersen, T. Fløyel, C. H. Bang-Berthelsen, P. Serup, O. D Madsen, J. Hald
    e19
    15-04-2010
    https://doi.org/10.4081/ejh.2010.e19
    1661
    PDF: 1021
    HTML: 3353
  • Investigating conversion of endplate chondrocytes induced by intermittent cyclic mechanical unconfined compression in three-dimensional cultures

    H.G. Xu, W. Zhang, Q. Zheng, Y.F. Yu, L.F. Deng, H. Wang, P. Liu, M. Zhang
    17-07-2014
    https://doi.org/10.4081/ejh.2014.2415
    1821
    PDF: 989
    HTML: 380
  • Novel understanding on genetic mechanisms of enteric neuropathies leading to severe gut dysmotility

    Francesca Bianco, Giulia Lattanzio, Luca Lorenzini, Chiara Diquigiovanni, Maurizio Mazzoni, Paolo Clavenzani, Laura Calzà, Luciana Giardino, Catia Sternini, Elena Bonora, Roberto De Giorgio
    25-11-2021
    https://doi.org/10.4081/ejh.2021.3289
    2717
    PDF: 1457
    HTML: 63
  • DNMT1 regulates IL-6- and TGF-β1-induced epithelial mesenchymal transition in prostate epithelial cells

    Hui Xu, Yanbo Chen, Qi Chen, Huan Xu, Yanxia Wang, Jiao Yu, Juan Zhou, Zhong Wang, Bing Xu
    03-05-2017
    https://doi.org/10.4081/ejh.2017.2775
    2797
    PDF: 1104
    HTML: 195
  • The role of miRNA-29b1 on the hypoxia-induced apoptosis in mammalian cardiomyocytes

    Bo Dai, Hailin Liu, Dingmin Juan, Kaize Wu, Ruhao Cao
    27-06-2024
    https://doi.org/10.4081/ejh.2024.4021
    1171
    PDF: 749
    HTML: 35
  • The Qi-Bang-Yi-Shen formula ameliorates renal dysfunction and fibrosis in rats with diabetic kidney disease via regulating PI3K/AKT, ERK and PPARγ signaling pathways

    Zhi Wang, Guihua Jian, Teng Chen, Yiping Chen, Junhui Li, Niansong Wang
    01-03-2023
    https://doi.org/10.4081/ejh.2023.3648
    5215
    PDF: 1200
    HTML: 49
  • Elastofibroma dorsi: a histochemical and immunohistochemical study

    A. Di Vito, E. Scali, G. Ferraro, C. Mignogna, I. Presta, C. Camastra, C. Palmieri, G. Donato, T. Barni
    19-02-2015
    https://doi.org/10.4081/ejh.2015.2459
    2851
    PDF: 990
    HTML: 1110
  • Folic acid promotes autophagy to relieve metabolism-associated fatty liver disease by regulating NRF2

    Yu Wen, Juan Luo, Chunjing Shi, Jie Wu
    03-11-2025
    https://doi.org/10.4081/ejh.2025.4309
    1140
    PDF: 656
    HTML: 45
  • miR-1270 enhances the proliferation, migration, and invasion of osteosarcoma via targeting cingulin

    Yang Liu, Weichun Guo, Shuo Fang, Bin He, Xiaohai Li, Li Fan
    07-12-2021
    https://doi.org/10.4081/ejh.2021.3237
    1853
    PDF: 648
    HTML: 37
  • Histochemistry as an irreplaceable approach for investigating functional cytology and histology

    C. Pellicciari
    e41
    19-12-2013
    https://doi.org/10.4081/ejh.2013.e41
    3475
    PDF: 968
    HTML: 414
  • E-cadherin inhibits the proliferation and migration of human colorectal cancer cells through Hippo signaling pathway

    Zhijing Wang, Xiaohua Qin, Shanshan Liu, Yilei Wen, Bikan Lan, Hantao Liao, Haixian Wei
    26-05-2025
    https://doi.org/10.4081/ejh.2025.4196
    1623
    PDF: 649
    HTML: 26
  • Knockdown of ARHGAP30 inhibits ovarian cancer cell proliferation, migration, and invasiveness by suppressing the PI3K/AKT/mTOR signaling pathway

    Xiaoyan Chu, Jun Lou, Yun Yi, Linlin Zhong, Ouping Huang
    11-05-2023
    https://doi.org/10.4081/ejh.2023.3653
    1585
    PDF: 764
    HTML: 48
  • Visnagin ameliorates myocardial ischemia/reperfusion injury through the promotion of autophagy and the inhibition of apoptosis

    Hai-rong Fu, Xiao-shan Li, Yong-hui Zhang, Bin-bin Feng, Lian-hong Pan
    07-09-2020
    https://doi.org/10.4081/ejh.2020.3131
    1390
    PDF: 991
    HTML: 20
  • Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

    Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou
    06-08-2025
    https://doi.org/10.4081/ejh.2025.4228
    1534
    PDF: 787
    HTML: 31
  • Quercetin reverses 5-fluorouracil resistance in colon cancer cells by modulating the NRF2/HO-1 pathway

    Zhongzhu Tang, Lei Wang, Yunwang Chen, Xiaomin Zheng, Runyu Wang, Bingxue Liu, Shiqi Zhang, Huimin Wang
    07-08-2023
    https://doi.org/10.4081/ejh.2023.3719
    2380
    PDF: 1130
    HTML: 35
  • Reelin expression in human liver of patients with chronic hepatitis C infection

    Simone Carotti, Giuseppe Perrone, Michelina Amato, Umberto Vespasiani Gentilucci, Daniela Righi, Maria Francesconi, Claudio Pellegrini, Francesca Zalfa, Maria Zingariello, Antonio Picardi, Andrea Onetti Muda, Sergio Morini
    17-03-2017
    https://doi.org/10.4081/ejh.2017.2745
    3446
    PDF: 1061
    HTML: 372
  • Cadmium influences the 5-Fluorouracil cytotoxic effects on breast cancer cells

    Y. Asara, J. A. Marchal, P. Bandiera, V. Mazzarello, L. G. Delogu, M. A. Sotgiu, A. Montella, R. Madeddu
    e1
    20-01-2012
    https://doi.org/10.4081/ejh.2012.e1
    1949
    PDF: 968
    HTML: 4627
  • Propofol alleviates M1 polarization and neuroinflammation of microglia in a subarachnoid hemorrhage model in vitro, by targeting the miR-140-5p/TREM-1/NF-κB signaling axis

    Lan Wang, Zhenyu Fan, Haijin Wang, Shougui Xiang
    17-09-2024
    https://doi.org/10.4081/ejh.2024.4034
    1382
    PDF: 767
    HTML: 20
  • Sodium hyaluronate promotes proliferation, autophagy, and migration of corneal epithelial cells by downregulating miR-18a in the course of corneal epithelial injury

    Yingzhuo Guo, Hua Wang
    15-06-2023
    https://doi.org/10.4081/ejh.2023.3663
    1650
    PDF: 714
    Supplementary: 147
    HTML: 33
  • Characterization of kynurenine pathway in patients with diarrhea-predominant irritable bowel syndrome

    Pingping Li, Jimin Zheng, Yun Bai, Dingxin Wang, Zijin Cui, Yueqin Li, Jian Zhang, Yuzhen Wang
    19-06-2020
    https://doi.org/10.4081/ejh.2020.3132
    2373
    PDF: 1234
    HTML: 27
  • Immunohistochemical localization of periostin in human gingiva

    T. Cobo, A. Obaya, S. Cal, L. Solares, R. Cabo, J.A. Vega, J. Cobo
    29-09-2015
    https://doi.org/10.4081/ejh.2015.2548
    2329
    PDF: 847
    HTML: 504
  • Clathrin-dependent endocytosis of membrane-bound RANKL in differentiated osteoclasts

    P. Narducci, R. Bortul, R. Bareggi, V. Nicolin
    e6
    08-03-2010
    https://doi.org/10.4081/ejh.2010.e6
    1840
    PDF: 599
    HTML: 6113
  • SRSF3 promotes the generation of XBP1s to stabilize autophagy and enhance hypoxia adaptation in glioma

    Bohu Liu, Xiaoran Zhang, Jintao Tian, Xiaobin Huang, Xuhui Li, Jinxi Zhao, Zhenghu Xu, Jun Pu
    03-03-2026
    https://doi.org/10.4081/ejh.2026.4530
    615
    PDF: 504
    HTML: 18
  • RXRα is upregulated in first trimester endometrial glands of spontaneous abortions unlike LXR and PPARγ

    J. Knabl, A. Vattai, R. Hüttenbrenner, S. Hutter, M. Karsten, U. Jeschke
    02-11-2016
    https://doi.org/10.4081/ejh.2016.2665
    2291
    PDF: 1136
    HTML: 325
  • miR-132 regulates the expression of synaptic proteins in APP/PS1 transgenic mice through C1q

    Nan Xu, Ang-Di Li, Li-Li Ji, Yao Ye, Zhen-Yu Wang, Lei Tong
    03-05-2019
    https://doi.org/10.4081/ejh.2019.3008
    3038
    PDF: 1267
    HTML: 29
  • Porphyromonas gingivalis lipopolysaccharide stimulation in human periodontal ligament stem cells: role of epigenetic modifications to the inflammation

    Francesca Diomede, Soundara Rajan Thangavelu, Ilaria Merciaro, Monica D'Orazio, Placido Bramanti, Emanuela Mazzon, Oriana Trubiani
    25-08-2017
    https://doi.org/10.4081/ejh.2017.2826
    3218
    PDF: 1374
    HTML: 153
  • P03 | ALTERED NEUROTRANSMISSION AND METABOLISM IN A GFAP R239C ZEBRAFISH MODEL OF ALEXANDER DISEASE S. Candiani1|2, M. Bozzo1, V. Bazzurro1, D. Bellitto3, A. Tripi1, S. Ferrando1, G. Rosa1, T. Bacchetti3 | 1Dept. of Biology, University of Genova, Italy; 2RCCS Azienda Ospedaliera Metropolitana, Genova, Italy; 3UO Proteomica e Spettrometria di Massa, IRCCS Ospedale Policlinico San Martino, Genova, Italy

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4699
    170
    PDF: 55
  • Effects mediated by the α7 nicotinic acetylcholine receptor on cell proliferation and migration in rat adipose-derived stem cells

    Marta Pernarella, Roberta Piovesana, Carlo Matera, Alessandro Faroni, Mario Fiore, Luciana Dini, Adam J. Reid, Clelia Dallanoce, Ada Maria Tata
    30-10-2020
    https://doi.org/10.4081/ejh.2020.3159
    1676
    PDF: 692
    HTML: 21
  • The Feulgen reaction: from pink-magenta to rainbow fluorescent at the Maffo Vialli’s School of Histochemistry

    Giuliano Mazzini
    22-02-2024
    https://doi.org/10.4081/ejh.2024.3971
    1744
    PDF: 570
    HTML: 21
  • MALAT1 regulates hypertrophy of cardiomyocytes by modulating the miR-181a/HMGB2 pathway

    Feng Chen, Wenfeng Li, Dandan Zhang, Youlin Fu, Wenjin Yuan, Gang Luo, Fuwei Liu, Jun Luo
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3426
    1580
    PDF: 1004
    HTML: 38
  • Cancer cell-derived exosomal miR-34a inhibits the malignant progression of pancreatic adenocarcinoma cells by restraining the M2 polarization of macrophages

    Kui Long, Xiang Kui, Qingbin Zeng, Wenzhi Dong
    17-04-2025
    https://doi.org/10.4081/ejh.2025.4176
    1594
    PDF: 703
    Supplementary: 143
    HTML: 51
  • New bitongling (NBTL) ameliorates rheumatoid arthritis in rats through inhibiting JAK2/STAT3 signaling pathway

    Xiang Li, Yu Xie, An Kang, Yue Wang
    17-02-2021
    https://doi.org/10.4081/ejh.2021.3202
    2647
    PDF: 1098
    HTML: 33
  • Astragaloside IV inhibits nasopharyngeal carcinoma progression by inhibiting SATB2/Wnt/PD-L1 pathway and enhancing the killing activity of T cells

    Yinping Zeng, Jiajun Huang, Tingting Duan, Xiaofeng Wang
    28-05-2026
    https://doi.org/10.4081/ejh.2026.4540
    433
    PDF: 305
    HTML: 15
  • Adipose mesenchymal stem cells-derived extracellular vesicles exert their preferential action in damaged central sites of SOD1 mice rather than peripherally

    Ermanna Turano, Federica Virla, Ilaria Scambi, Sylwia Dabrowska, Oluwamolakun Bankole, Raffaella Mariotti
    04-07-2024
    https://doi.org/10.4081/ejh.2024.4040
    2204
    PDF: 734
    HTML: 32
  • Polydatin reverses oxidation low lipoprotein (oxLDL)-induced apoptosis of human umbilical vein endothelial cells via regulating the miR-26a-5p/BID axis

    Dajie Wang, Zhaofeng Zhou, Liang Yuan
    20-09-2022
    https://doi.org/10.4081/ejh.2022.3505
    1466
    PDF: 674
    HTML: 51
  • Deleted in Liver Cancer 2 (DLC2) protein expression in hepatocellular carcinoma

    Dominika Wolosz, Agnieszka Walczak, Grzegorz Szparecki, Michal Dwojak, Magdalena Winiarska, Ewa Wolinska, Barbara Gornicka
    18-02-2019
    https://doi.org/10.4081/ejh.2019.2981
    1571
    PDF: 815
    HTML: 41
  • Genetic deletion of P-selectin prevents fibrosis development by inhibiting the neutrophil megakaryocyte emperipolesis in the Gata1low mouse model for myelofibrosis

    Francesca Arciprete, Viola Velardi, Antonio Di Virgilio, Paola Verachi, Claudio Carta, Giulia Pozzi, Vincenzo Roberti, Giorgio Vivacqua, Rosalba Rana, Maria Zingariello
    16-12-2025
    https://doi.org/10.4081/ejh.2025.4427
    888
    PDF: 433
    HTML: 16
  • Different fusion tags affect the activity of ubiquitin overexpression on spastin protein stability

    Jianyu Zou, Zhenbin Cai, Zhi Liang , Yaozhong Liang, Guowei Zhang, Jie Yang, Yunlong Zhang, Hongsheng Lin, Minghui Tan
    07-12-2021
    https://doi.org/10.4081/ejh.2021.3352
    1852
    PDF: 866
    HTML: 44
  • The possible prognostic role of histone deacetylase and transforming growth factor β/Smad signaling in high grade gliomas treated by radio-chemotherapy: a preliminary immunohistochemical study

    Roberta Sferra, Simona Pompili, Claudio Festuccia, Francesco Marampon, Giovanni L. Gravina, Luca Ventura, Ernesto Di Cesare, Sara Cicchinelli, Eugenio Gaudio, Antonella Vetuschi
    16-05-2017
    https://doi.org/10.4081/ejh.2017.2732
    2801
    PDF: 1093
    HTML: 163
  • 28 | 3D MORPHO-FUNCTIONAL RECONSTRUCTION OF THE PREPUBERTAL MOUSE OVARY COMBINING NANO-COMPUTED TOMOGRAPHY AND CONFOCAL IMAGING A. Fantinato1|4, G. Fiorentino1|4, A. Parrilli2, G. Brazzale1, V. Merico1, P. Rebuzzini1, D. Cimadomo1|3, S. Garagna1, M. Zuccotti1 | 1Dept. of Biology and Biotechnology, University of Pavia, Italy; 2Empa-Swiss Federal Laboratories for Materials Science and Technology, Switzerland; 3IVIRMA Global Research Alliance, Genera, Clinica Valle Giulia, Italy; 4Equal contribution

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4646
    117
    PDF: 57
  • DPY30 promotes the growth and survival of osteosarcoma cell by regulating the PI3K/AKT signal pathway

    Gong Cheng, Fengmin An, Zhilin Cao, Mingdi Zheng, Zhongyuan Zhao, Hao Wu
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3413
    1424
    PDF: 722
    Supplementary: 120
    HTML: 43
  • Leptin affects filopodia and cofilin in NK-92 cells in a dose- and time-dependent manner

    Jana Oswald, Maximilian Büttner, Simon Jasinski-Bergner, Roland Jacobs, Philip Rosenstock, Heike Kielstein
    26-01-2018
    https://doi.org/10.4081/ejh.2018.2848
    3448
    PDF: 1270
    HTML: 126
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
Nana Bao et al.
20 April 2026
Vol. 70 No. 2 (2026)
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells
Huina Su et al.
21 April 2026
Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

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