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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

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  • Therapeutic effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles on ovarian functions through the PI3K/Akt cascade in mice with premature ovarian failure

    Nan Li, Xue Fan, Lihong Liu, Yanbing Liu
    27-07-2023
    https://doi.org/10.4081/ejh.2023.3506
    1697
    PDF: 1044
    HTML: 22
  • Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function

    Zhijiang Chen, Huili Wang, Bin Hu, Xinxin Chen, Meiyu Zheng, Lili Liang, Juanjuan Lyu, Qiyi Zeng
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3412
    2451
    PDF: 1401
    HTML: 31
  • Developmental immunolocalization of the Klotho protein in mouse kidney epithelial cells

    J.H. Song, M.Y. Lee, Y.J. Kim, S.R. Park, J. Kim, S.Y. Ryu, J.Y. Jung
    24-01-2014
    https://doi.org/10.4081/ejh.2014.2256
    3697
    PDF: 909
    HTML: 509
  • Dipeptidylpeptidase-IV activity and expression reveal decreased damage to the intrahepatic biliary tree in fatty livers submitted to subnormothermic machine-perfusion respect to conventional cold storage

    E. Tarantola, V. Bertone, G. Milanesi, C. Gruppi, A. Ferrigno, M. Vairetti, S. Barni, I. Freitas
    17-07-2014
    https://doi.org/10.4081/ejh.2014.2414
    1873
    PDF: 795
    HTML: 572
  • Expression patterns of α2,3-Sialyltransferase I and α2,6-Sialyltransferase I in human cutaneous epithelial lesions

    S.A. Ferreira, J.L.A. Vasconcelos, R.C.W.C. Silva, C.L.B. Cavalcanti, C.L. Bezerra, M.J.B.M. Rêgo, E.I.C. Beltrão
    e7
    14-02-2013
    https://doi.org/10.4081/ejh.2013.e7
    1507
    PDF: 741
    HTML: 232
  • Influence of surgical and chemical orchidectomy on weight and distribution of AChE-nerve fibres in thymuses of adult rats

    F. Dorko, D. Kluchová, A. Boleková, K. Lovasová, T. Špakovská, T. Borošová
    e22
    12-07-2011
    https://doi.org/10.4081/ejh.2011.e22
    1814
    PDF: 533
    HTML: 2515
  • Aortic dissection is associated with reduced polycystin-1 expression, an abnormality that leads to increased ERK phosphorylation in vascular smooth muscle cells

    J. Feng, S. Ge, L. Zhang, H. Che, C. Liang
    16-12-2016
    https://doi.org/10.4081/ejh.2016.2711
    2609
    PDF: 1000
    HTML: 307
  • The lncRNA MEG3 promotes trophoblastic cell growth and invasiveness in preeclampsia by acting as a sponge for miR-21, which regulates BMPR2 levels

    Huyi Liu, Xiangdao Cai , Jia Liu, Fengxiang Zhang , Andong He, Ruiman Li
    25-11-2021
    https://doi.org/10.4081/ejh.2021.3323
    1865
    PDF: 679
    HTML: 31
  • Colorimetric and fluorescent TRAP assays for visualising and quantifying fish osteoclast activity

    Lalith Prabha Ethiraj, En Lei Samuel Fong, Ranran Liu, Madelynn Chan, Christoph Winkler, Tom James Carney
    24-03-2022
    https://doi.org/10.4081/ejh.2022.3369
    2562
    PDF: 1606
    HTML: 95
  • Seasonal patterns of prolactin, prolactin receptor, and STAT5 expression in the ovaries of wild ground squirrels (Citellus dauricus Brandt)

    Qingjing Gao, Wenqian Xie, Wenjing Lu, Yuning Liu, Haolin Zhang, Yingying Han, Qiang Weng
    02-10-2023
    https://doi.org/10.4081/ejh.2023.3825
    958
    PDF: 504
    HTML: 27
  • Folliculostellate cells in pituitary pars distalis of male viscacha: immunohistochemical, morphometric and ultrastructural study

    M. Acosta, V. Filippa, F. Mohamed
    e1
    20-01-2010
    https://doi.org/10.4081/ejh.2010.e1
    10450
    PDF: 1072
    HTML: 15060
  • Immunoreactivity and a new staining method of monocarboxylate transporter 1 located in endothelial cells of cerebral vessels of human brain in distinguishing cerebral venules from arterioles

    Yuan Cao, Dong-Hui Ao, Chao Ma, Wen-Ying Qiu, Yi-Cheng Zhu
    01-10-2021
    https://doi.org/10.4081/ejh.2021.3306
    1488
    PDF: 781
    HTML: 25
    Supplementary: 132
  • Detection and characterisation of NAD(P)H-diaphorase activity in Dictyostelium discoideum cells (Protozoa)

    A. Amaroli, M.G. Chessa
    e47
    29-10-2012
    https://doi.org/10.4081/ejh.2012.e47
    1483
    PDF: 646
    HTML: 527
  • Immunolocalization of endocan during the endothelial-mesenchymal transition process

    L. M. Carrillo, E. Arciniegas, H. R. Rojas, R. E. Ramirez
    e13
    01-06-2011
    https://doi.org/10.4081/ejh.2011.e13
    1400
    PDF: 554
    HTML: 1348
  • Expressions of IL-6, TNF-α and NF-κB in the skin of Chinese brown frog (Rana dybowskii)

    Liqin Xi, Chen Wang, Pengyu Chen, Qi Yang, Ruiqi Hu, Haolin Zhang, Qiang Weng, Meiyu Xu
    19-10-2017
    https://doi.org/10.4081/ejh.2017.2834
    2416
    PDF: 873
    HTML: 64
  • Low ozone concentrations stimulate cytoskeletal organization, mitochondrial activity and nuclear transcription

    M. Costanzo, B. Cisterna, A. Vella, T. Cestari, V. Covi, G. Tabaracci, M. Malatesta
    21-04-2015
    https://doi.org/10.4081/ejh.2015.2515
    3061
    PDF: 1001
    HTML: 410
  • Cannabinoid CB2 receptors are involved in the protection of RAW264.7 macrophages against the oxidative stress: an in vitro study

    Sabrina Giacoppo, Agnese Gugliandolo, Oriana Trubiani, Federica Pollastro, Gianpaolo Grassi, Placido Bramanti, Emanuela Mazzon
    23-01-2017
    https://doi.org/10.4081/ejh.2017.2749
    6006
    PDF: 1354
    HTML: 400
  • Expression profile of the zinc transporter ZnT3 in taste cells of rat circumvallate papillae and its role in zinc release, a potential mechanism for taste stimulation

    Kentaro Nishida, Saho Bansho, Akiko Ikukawa, Teruyo Kubota, Akihiro Ohishi, Kazuki Nagasawa
    10-11-2022
    https://doi.org/10.4081/ejh.2022.3534
    1294
    PDF: 717
    Supplementary: 171
    HTML: 34
  • Immunohistochemical demonstration of keratins in the epidermal layers of the Malayan pangolin (Manis javanica), with remarks on the evolution of the integumental scale armour

    W. Meyer, M. Liumsiricharoen, A. Suprasert, L.G. Fleischer, M. Hewicker-Trautwein
    e27
    16-09-2013
    https://doi.org/10.4081/ejh.2013.e27
    3469
    PDF: 1154
    HTML: 517
  • Testicular expression of NGF, TrkA and p75 during seasonal spermatogenesis of the wild ground squirrel (Citellus dauricus Brandt)

    H. Zhang, Y. Wang, J. Zhang, L. Wang, Q. Li, X. Sheng, Y. Han, Z. Yuan, Q. Weng
    10-08-2015
    https://doi.org/10.4081/ejh.2015.2522
    1602
    PDF: 814
    HTML: 493
  • circRNA-79530 regulates Twist-mediated mitochondrial damage via sponging miR-214 affecting hypoxia/reoxygenation-induced injury in H9c2 cardiomyocytes

    Ziyang Yu, Wenbo Xu, Yirong Teng, Tingting Li, Ren Guo, Ju Li, Xichen Li, Yanping Li, Yinglu Hao
    22-08-2025
    https://doi.org/10.4081/ejh.2025.4230
    362
    PDF: 284
    HTML: 5
  • Effect of thyroxine on munc-18 and syntaxin-1 expression in dorsal hippocampus of adult-onset hypothyroid rats

    Y. Zhu, D. Ning, F. Wang, C. Liu, Y. Xu, X. Jia, D. Zhu
    e22
    22-05-2012
    https://doi.org/10.4081/ejh.2012.22
    1062
    PDF: 555
    HTML: 1352
  • Immunohistochemical localization of nerve fibers in the pseudocapsule of fibroids

    Y. Sun, L. Zhu, X. Huang, C. Zhou, X. Zhang
    08-05-2014
    https://doi.org/10.4081/ejh.2014.2249
    2741
    PDF: 925
    HTML: 1356
  • Extracellular vesicles from bone mesenchymal stem cells transport microRNA-206 into osteosarcoma cells and target NRSN2 to block the ERK1/2-Bcl-xL signaling pathway

    Alimu Keremu, Pazila Aila, Aikebaier Tusun , Maimaitiaili Abulikemu, Xiaoguang Zou
    22-06-2022
    https://doi.org/10.4081/ejh.2022.3394
    1940
    PDF: 1268
    HTML: 27
  • Leptin affects filopodia and cofilin in NK-92 cells in a dose- and time-dependent manner

    Jana Oswald, Maximilian Büttner, Simon Jasinski-Bergner, Roland Jacobs, Philip Rosenstock, Heike Kielstein
    26-01-2018
    https://doi.org/10.4081/ejh.2018.2848
    3314
    PDF: 1199
    HTML: 114
  • Deletion of osteopontin in non-small cell lung cancer cells affects bone metabolism by regulating miR-34c/Notch1 axis: a clue to bone metastasis

    Jing Guo, Chang-Yong Tong, Jian-Guang Shi, Xin-Jian Li, Xue-Qin Chen
    26-07-2023
    https://doi.org/10.4081/ejh.2023.3631
    1344
    PDF: 744
    HTML: 25
  • Endoplasmic reticulum stress contributed to inflammatory bowel disease by activating p38 MAPK pathway

    Yan Long, Yan Zhao, Xiaoqing Ma, Ya Zeng, Tian Hu, Weijie Wu, Chongtian Deng, Jinyue Hu, Yueming Shen
    23-05-2022
    https://doi.org/10.4081/ejh.2022.3415
    2272
    PDF: 1154
    HTML: 55
  • Subcellular distribution and expression of cofilin and ezrin in human colon adenocarcinoma cell lines with different metastatic potential

    D. Nowak, A. J. Mazur, A. Popow-Woźniak, A. Radwańska, H. G. Mannherz, M. Malicka-Błaszkiewicz
    e14
    13-04-2010
    https://doi.org/10.4081/ejh.2010.e14
    1731
    PDF: 636
    HTML: 2677
  • Degenerative effects in rat eyes after experimental ocular hypertension

    G. Scarsella, M. Nebbioso, S. Stefanini, N. Pescosolido
    e42
    08-10-2012
    https://doi.org/10.4081/ejh.2012.e42
    1532
    PDF: 592
    HTML: 202
  • Immunological detection of m- and µ-calpains in the skeletal muscle of Marchigiana cattle

    E. Varricchio, M.G. Russolillo, L. Maruccio, S. Velotto, G. Campanile, M. Paolucci, F. Russo
    e2
    14-01-2013
    https://doi.org/10.4081/ejh.2013.e2
    8035
    PDF: 740
    HTML: 529
  • Excitatory Amino Acid Transporter 5 is widely expressed in peripheral tissues

    A. Lee, A.R. Anderson, M. Stevens, S. Beasley, N.L. Barnett, D.V. Pow
    e11
    12-03-2013
    https://doi.org/10.4081/ejh.2013.e11
    2945
    PDF: 751
    Supplementary: 238
    HTML: 435
  • Expression of nestin, parvalbumin and otoferlin during cochlear development in the mouse: an immunofluorescence study

    Wenjing Liu, Yongchun Zhang, Cheng Liang, Shujuan Yang
    22-09-2025
    https://doi.org/10.4081/ejh.2025.4242
    573
    PDF: 447
    Supplementary: 47
    HTML: 9
  • Effects of chronic exposure to bisphenol A in adult female mice on social behavior, vasopressin system, and estrogen membrane receptor (GPER1)

    Brigitta Bonaldo, Antonino Casile, Martina Bettarelli, Stefano Gotti, GianCarlo Panzica, Marilena Marraudino
    10-11-2021
    https://doi.org/10.4081/ejh.2021.3272
    2287
    PDF: 1020
    HTML: 46
  • Protective effect of different antioxidant agents in UVB-irradiated keratinocytes

    Sara Salucci, Sabrina Burattini, Francesca Buontempo, Alberto Maria Martelli, Elisabetta Falcieri, Michela Battistelli
    18-09-2017
    https://doi.org/10.4081/ejh.2017.2784
    2450
    PDF: 992
    HTML: 185
  • New insights into the in situ microscopic visualization and quantification of inorganic polyphosphate stores by 4',6-diamidino-2-phenylindole (DAPI)-staining

    F.M. Gomes, I.B. Ramos, C. Wendt, W. Girard-Dias, W. De Souza, E.A. Machado, K. Miranda
    e34
    05-11-2013
    https://doi.org/10.4081/ejh.2013.e34
    4437
    PDF: 1970
    HTML: 602
  • Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice

    Nana Bao, Min Zhang, Ming Tang, Ziyi Shen, Shenglin Wang, Guohui Jiang
    20-04-2026
    https://doi.org/10.4081/ejh.2026.4548
    328
    PDF: 230
    Raw data: 37
    HTML: 14
  • Seasonal expression of androgen receptor, aromatase, and estrogen receptor alpha and beta in the testis of the wild ground squirrel (Citellus dauricus Brandt)

    Q. Li, F. Zhang, S. Zhang, X. Sheng, X. Han, Q. Weng, Z. Yuan
    17-02-2015
    https://doi.org/10.4081/ejh.2015.2456
    2442
    PDF: 847
    HTML: 708
  • Cartilage canals in newborn dogs: histochemical and immunohistochemical findings

    A. Di Giancamillo, M.E. Andreis, P. Taini, M.C. Veronesi, M. Di Giancamillo, S.C. Modina
    15-09-2016
    https://doi.org/10.4081/ejh.2016.2701
    1493
    PDF: 718
    Supplementary: 293
    HTML: 215
  • Are podoplanin and ezrin involved in the invasion process of the ameloblastomas?

    Y.F. Costa, K.C. Tjioe, S. Nonogaki, F.A. Soares, J.R. Pereira Lauris, D. Tostes Oliveira
    24-02-2015
    https://doi.org/10.4081/ejh.2015.2451
    1986
    PDF: 703
    HTML: 715
  • Immunoreactivity of thymosin beta 4 in human foetal and adult genitourinary tract

    S. Nemolato, T. Cabras, M.U. Fanari, F. Cau, D. Fanni, C. Gerosa, B. Manconi, I. Messana, M. Castagnola, G. Faa
    e43
    13-10-2010
    https://doi.org/10.4081/ejh.2010.e43
    1463
    PDF: 583
    HTML: 959
  • Phosphorylation mutation impairs the promoting effect of spastin on neurite outgrowth without affecting its microtubule severing ability

    Yunlong Zhang, Xin He, Jianyu Zou, Jie Yang, Ao Ma, Minghui Tan
    12-01-2023
    https://doi.org/10.4081/ejh.2023.3594
    1453
    PDF: 775
    HTML: 33
  • Expression of S100β during mouse cochlear development

    Wenjing Liu, Yongchun Zhang, Cheng Liang, Lizhong Su
    10-03-2025
    https://doi.org/10.4081/ejh.2025.4189
    1398
    PDF: 375
    Supplementary: 72
    HTML: 7
  • P41 | INVOLVEMENT OF THE DOLPHIN’S MELON IN IMMUNE FUNCTION G.P. Lombardo1, A. Miller2, L. Spiccia1, V. Natale1, F. Pellicanò1, G. Squadrito1, E. R. Lauriano1 | 1Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina; 2Department of Veterinary Sciences, University of Messina, Messina, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4363
    201
  • Tanshinone IIA attenuates hepatic stellate cell activation, oxidative stress, and liver fibrosis by inhibiting YAP signaling

    Dan Wang, Qingquan Tan, Qing Zheng, Yanling Ma, Li Feng
    17-06-2025
    https://doi.org/10.4081/ejh.2025.4218
    1280
    PDF: 536
    HTML: 26
  • Interindividual variability in the expression of surfactant protein A and B in the human lung during development

    F. Cau, E. Pisu, C. Gerosa, G. Senes, F. Ronchi, C. Botta, E. Di Felice, F. Uda, V. Marinelli, G. Faa, V. Fanos, C. Moretti, D. Fanni
    26-09-2016
    https://doi.org/10.4081/ejh.2016.2678
    2027
    PDF: 770
    Supplementary: 254
    HTML: 386
  • Differential expression of KCNQ1 K+ channel in tubular cells of frog kidney

    S. Ćirović, J. Marković-Lipkovski, J. Todorović, J. Nešović-Ostojić, M. Jović, S. Ilić, S. Tatić, D. Čemerikić
    e7
    08-02-2010
    https://doi.org/10.4081/ejh.2010.e7
    1657
    PDF: 484
    HTML: 3631
  • THE USE OF BIOMIMETIC 2D AND 3D UROTHELIAL IN VITRO MODELS WITH MOLECULAR, MORPHOLOGICAL AND FUNCTIONAL CHARACTERISTICS OF NORMAL AND CANCEROUS BLADDER TISSUE AS AN ALTERNATIVE METHOD IN PRECLINICAL STUDIES M.E. Kreft1, L. Tratnjek1, A. Janev1, N. Resnik1, U. Cerkvenik1, U. D. Jerman1, G. Markovič1, T.Ž. Ramuta1, T. Višnjar1, Ž. Sardoč1, A.Punčuh1, S. Kralj2, M. Čemažar3, P. Veranič1 |1Institute of Cell Biology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia; 2Department for Materials Synthesis, Jožef Stefan Institute, Ljubljana, Slovenia; 3Institute of Oncology Ljubljana, Ljubljana, Slovenia

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4288
    217
  • WT1 expression in the human fetus during development

    R. Ambu, L. Vinci, C. Gerosa, D. Fanni, E. Obinu, A. Faa, V. Fanos
    29-06-2015
    https://doi.org/10.4081/ejh.2015.2499
    2220
    PDF: 837
    HTML: 983
  • Quantitative evaluation of CART-containing cells in urinary bladder of rats with renovascular hypertension

    I. Janiuk, I. Kasacka
    13-04-2015
    https://doi.org/10.4081/ejh.2015.2446
    2158
    PDF: 655
    HTML: 397
  • STAT3 and SOCS3 expression patterns during murine placenta development

    S. San Martin, J. Fitzgerald, M. Weber, M. Párraga, T. Sáez, T.M. Zorn, U.R. Markert
    e19
    28-06-2013
    https://doi.org/10.4081/ejh.2013.e19
    3624
    PDF: 843
    HTML: 315
  • Regulatory roles of ACSL5 in the anti-tumor function of palmitic acid (C16:0) via the ERK signaling pathway

    Jiapei Lv, Wang Yanting, Shan Wei
    08-11-2023
    https://doi.org/10.4081/ejh.2023.3867
    2002
    PDF: 970
    HTML: 47
  • Celecoxib treatment does not alter recruitment and activation of osteoclasts in the initial phase of experimental tooth movement

    E.P. Carvalho-Filho, A.C. Stabile, E. Ervolino, M.B.S. Stuani, M.M. Iyomasa, M.J.A. Rocha
    e43
    08-10-2012
    https://doi.org/10.4081/ejh.2012.e43
    1583
    PDF: 688
    HTML: 435
  • Postnatal development of thalamic reticular nucleus projections to the anterior thalamic nuclei in rats

    Hitoshi Fujita, Kosuke Imura, Masahito Takiguchi, Kengo Funakoshi
    24-03-2022
    https://doi.org/10.4081/ejh.2022.3370
    1590
    PDF: 1048
    HTML: 32
  • E-cadherin inhibits the proliferation and migration of human colorectal cancer cells through Hippo signaling pathway

    Zhijing Wang, Xiaohua Qin, Shanshan Liu, Yilei Wen, Bikan Lan, Hantao Liao, Haixian Wei
    26-05-2025
    https://doi.org/10.4081/ejh.2025.4196
    1115
    PDF: 509
    HTML: 16
  • The usefulness of c-Kit in the immunohistochemical assessment of melanocytic lesions

    L. Pilloni, P. Bianco, E. DiFelice, S. Cabras, M.E. Castellanos, L. Atzori, C. Ferreli, P. Mulas, S. Nemolato, G. Faa
    e20
    07-06-2011
    https://doi.org/10.4081/ejh.2011.e20
    1309
    PDF: 693
    HTML: 9927
  • Optimization of the tartrate-resistant acid phosphatase detection by histochemical method

    M. J. Galvão, A. Santos, M. D. Ribeiro, A. Ferreira, F. Nolasco
    e1
    18-02-2011
    https://doi.org/10.4081/ejh.2011.e1
    1521
    PDF: 708
    HTML: 853
  • Cancer cell-derived exosomal miR-34a inhibits the malignant progression of pancreatic adenocarcinoma cells by restraining the M2 polarization of macrophages

    Kui Long, Xiang Kui, Qingbin Zeng, Wenzhi Dong
    17-04-2025
    https://doi.org/10.4081/ejh.2025.4176
    1342
    PDF: 597
    Supplementary: 109
    HTML: 44
  • Immunohistochemical study of subepidermal connective of molluscan integument

    S Corbetta, A Bairati, L Vitellaro Zuccarello
    259-72
    23-01-2010
    https://doi.org/10.4081/1688
    782
    PDF: 1222
  • Transient receptor potential canonical 3/5 attenuate endothelial damage-induced neointima formation without affecting endothelial cell proliferation

    Wenjun Zeng, Bei Liu, Lixia Yang, Ruiwei Guo
    19-11-2025
    https://doi.org/10.4081/ejh.2025.4311
    383
    PDF: 194
    HTML: 17
  • LOX-1 deficient mice show resistance to zymosan-induced arthritis

    Kazuhiko Hashimoto, Yutaka Oda, Koichi Nakagawa, Terumasa Ikeda, Kazuhiro Ohtani, Masao Akagi
    22-01-2018
    https://doi.org/10.4081/ejh.2018.2847
    2048
    PDF: 869
    HTML: 76
  • KISS1 and KISS1R expression in the human and rat carotid body and superior cervical ganglion

    A. Porzionato, G. Fenu, M. Rucinski, V. Macchi, A. Montella, L. K. Malendowicz, R. De Caro
    e14
    04-05-2011
    https://doi.org/10.4081/ejh.2011.e14
    1258
    PDF: 540
    HTML: 1057
  • Immunofluorescent characterization of non-myelinating Schwann cells and their interactions with immune cells in mouse mesenteric lymph node

    Zhongli Shi, Wayne K. Greene, Philip K. Nicholls, Dailun Hu, Janina E.E. Tirnitz-Parker, Qionglan Yuan, Changfu Yin, Bin Ma
    07-08-2017
    https://doi.org/10.4081/ejh.2017.2827
    2402
    PDF: 964
    HTML: 160
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
Nana Bao et al.
20 April 2026
Vol. 70 No. 2 (2026)
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells
Huina Su et al.
21 April 2026
Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

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