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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

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  • Toll-like receptor 4 expression in the epithelium of inflammatory periapical lesions. An immunohistochemical study

    R. Leonardi, R.E. Perrotta, C. Loreto, G. Musumeci, S. Crimi, J.N. dos Santos, M.C. Rusu, P. Bufo, E. Barbato, G. Pannone
    26-10-2015
    https://doi.org/10.4081/ejh.2015.2547
    1783
    PDF: 1025
    HTML: 352
  • Dexmedetomidine attenuates neuroinflammation and microglia activation in LPS-stimulated BV2 microglia cells through targeting circ-Shank3/miR-140-3p/TLR4 axis

    Guangbao He, Yibo He, Hongwei Ni, Kai Wang, Yijun Zhu, Yang Bao
    26-07-2023
    https://doi.org/10.4081/ejh.2023.3766
    1760
    PDF: 1153
    HTML: 13
  • Mucin1 relieves acute lung injury by inhibiting inflammation and oxidative stress

    Chunlin Ye, Bin Xu, Jie Yang, Yunkun Liu, Zhikai Zeng, Lingchun Xia, Quanjin Li, Guowen Zou
    02-12-2021
    https://doi.org/10.4081/ejh.2021.3331
    2422
    PDF: 1397
    HTML: 35
  • MyD88/ERK/NFkB pathways and pro-inflammatory cytokines release in periodontal ligament stem cells stimulated by Porphyromonas gingivalis

    Francesca Diomede, Maria Zingariello, Marcos F.X.B. Cavalcanti, Ilaria Merciaro, Jacopo Pizzicannella, Natalia de Isla, Sergio Caputi, Patrizia Ballerini, Oriana Trubiani
    24-05-2017
    https://doi.org/10.4081/ejh.2017.2791
    3097
    PDF: 1326
    HTML: 148
  • Effects of piperlonguminine on lung injury in severe acute pancreatitis via the TLR4/NF-κB pathway

    Qian Hu, Ran Tao, Xiaoyun Hu, Haibo Wu, Jianjun Xu
    20-03-2023
    https://doi.org/10.4081/ejh.2023.3639
    1137
    PDF: 669
    HTML: 21
  • Pretreatment with geniposide mitigates myocardial ischemia/reperfusion injury by modulating inflammatory response through TLR4/NF-κB pathway

    Yanmei Yao, Leqing Lin, Wenxue Tang, Yueliang Shen, Fayu Chen, Ning Li, Baiyong Wang
    08-09-2023
    https://doi.org/10.4081/ejh.2023.3742
    1004
    PDF: 441
    HTML: 18
  • Inhibition of HMGB1 suppresses inflammation and catabolism in temporomandibular joint osteoarthritis via NF-κB signaling pathway

    Yan Yan Li, Ya Ping Feng, Li Liu, Jin Ke, Xing Long
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3357
    1613
    PDF: 1048
    HTML: 23
  • Propofol alleviates M1 polarization and neuroinflammation of microglia in a subarachnoid hemorrhage model in vitro, by targeting the miR-140-5p/TREM-1/NF-κB signaling axis

    Lan Wang, Zhenyu Fan, Haijin Wang, Shougui Xiang
    17-09-2024
    https://doi.org/10.4081/ejh.2024.4034
    1052
    PDF: 506
    HTML: 7
  • ECRG4 expression in normal rat tissues: expression study and literature review

    A. Porzionato, M. Rucinski, V. Macchi, G. Sarasin, L.K. Malendowicz, R. De Caro
    18-05-2015
    https://doi.org/10.4081/ejh.2015.2458
    2844
    PDF: 1129
    Supplementary: 362
    HTML: 1011
  • circRNA-79530 regulates Twist-mediated mitochondrial damage via sponging miR-214 affecting hypoxia/reoxygenation-induced injury in H9c2 cardiomyocytes

    Ziyang Yu, Wenbo Xu, Yirong Teng, Tingting Li, Ren Guo, Ju Li, Xichen Li, Yanping Li, Yinglu Hao
    22-08-2025
    https://doi.org/10.4081/ejh.2025.4230
    318
    PDF: 235
    HTML: 4
  • Polydatin reverses oxidation low lipoprotein (oxLDL)-induced apoptosis of human umbilical vein endothelial cells via regulating the miR-26a-5p/BID axis

    Dajie Wang, Zhaofeng Zhou, Liang Yuan
    20-09-2022
    https://doi.org/10.4081/ejh.2022.3505
    1207
    PDF: 570
    HTML: 37
  • DNMT1 regulates IL-6- and TGF-β1-induced epithelial mesenchymal transition in prostate epithelial cells

    Hui Xu, Yanbo Chen, Qi Chen, Huan Xu, Yanxia Wang, Jiao Yu, Juan Zhou, Zhong Wang, Bing Xu
    03-05-2017
    https://doi.org/10.4081/ejh.2017.2775
    2632
    PDF: 951
    HTML: 170
  • Effects of miR-939 and miR-376A on ulcerative colitis using a decoy strategy to inhibit NF-κB and NFAT expression

    Yongwei Lin, Zhipeng Zhou, Lang Xie, Yongsheng Huang, Zhenghua Qiu, Lili Ye, Chunhui Cui
    15-02-2022
    https://doi.org/10.4081/ejh.2022.3316
    1783
    PDF: 707
    HTML: 24
  • Study on the mechanism of Shenling Baizhu powder on the pathogenesis of pregnancy complicated with non-alcoholic fatty liver, based on PI3K/AKT/mTOR signal pathway

    Yao Le, Zhijun Wang, Qian Zhang, Ling Miao, Xiaohong Wang, Guorong Han
    17-09-2024
    https://doi.org/10.4081/ejh.2024.4093
    2122
    PDF: 513
    HTML: 41
  • Placental mesenchymal stem cell exosomes drive macrophage M2 polarization via the miR-146a-5p/TRAF6 axis to ameliorate preeclampsia

    Xiaoli Liu, Ruiyue Li, Junjie Sun, Yuanpei Yang, Lina Hu
    17-11-2025
    https://doi.org/10.4081/ejh.2025.4426
    616
    PDF: 363
    HTML: 13
  • P52 | MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL EVALUATION OF THE ANTI-INFLAMMATORY AND ANTIOXIDANT PROPERTIES OF HEMP EXTRACTS ON THE LIVER OF RATS INVOLVED IN INFLAMMATION CAUSED BY LPS A. Miller1, M. Kotanska2, M. Bednarski2, G.P. Lombardo3, V. Natale3, G. Pirracchio3, L. Spiccia3, S. Pergolizzi3, G. Rizzo4, E.R. Lauriano3 | 1Department of Veterinary Sciences, University of Messina, Messina, Italy; 2Department of Pharmacological Screening, Jagiellonian University Medical College, Kraków, Poland: 3Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina, Italy; 4Department of Clinical and Experimental Medicine, University of Messina, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4374
    244
  • Sodium hyaluronate promotes proliferation, autophagy, and migration of corneal epithelial cells by downregulating miR-18a in the course of corneal epithelial injury

    Yingzhuo Guo, Hua Wang
    15-06-2023
    https://doi.org/10.4081/ejh.2023.3663
    1201
    PDF: 578
    Supplementary: 95
    HTML: 23
  • Low ozone concentrations stimulate cytoskeletal organization, mitochondrial activity and nuclear transcription

    M. Costanzo, B. Cisterna, A. Vella, T. Cestari, V. Covi, G. Tabaracci, M. Malatesta
    21-04-2015
    https://doi.org/10.4081/ejh.2015.2515
    2989
    PDF: 965
    HTML: 407
  • Deubiquitinase USP14 is upregulated in Crohn's disease and inhibits the NOD2 pathway mediated inflammatory response in vitro

    Mengling Li, Yan Zhao, Jiayi Zhang, Wang Jiang, Siyuan Peng, Jinyue Hu, Yueming Shen
    09-09-2024
    https://doi.org/10.4081/ejh.2024.4101
    1167
    PDF: 389
    HTML: 9
  • From the intestinal mucosal barrier to the enteric neuromuscular compartment: an integrated overview on the morphological changes in Parkinson’s disease

    Carolina Pellegrini, Vanessa D'Antongiovanni, Chiara Ippolito, Cristina Segnani, Luca Antonioli, Matteo Fornai, Nunzia Bernardini
    22-11-2021
    https://doi.org/10.4081/ejh.2021.3278
    1391
    PDF: 803
    HTML: 36
  • P74 | EXPRESSION OF PISCIDIN, TLR-4, ERK2 AND P-P38 MAPK IN THE ZEBRAFISH GUT EXPOSED TO PCB-126 AND POSSIBLE PROTECTIVE EFFECTS OF GINESTEIN L. Spiccia1, A. Miller2, G.P. Lombardo1, V. Natale1, F. Pellicanò1, S. Marino1, A. Nunnari1, A. Migliorato3, E.R. Laurian1 | 1Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina, Italy; 2Department of Veterinary Sciences, University of Messina, Messina, Italy; 3Department of Biomedical and Dental Sciences and Morphofunctional Images, University of Messina, Messina, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4399
    208
  • Pretreatment with interleukin-15 attenuates inflammation and apoptosis by inhibiting NF-κB signaling in sepsis-induced myocardial dysfunction

    Chaojie He, Yi Yu, Feifan Wang, Wudi Li, Hui Ni, Meixiang Xiang
    29-04-2024
    https://doi.org/10.4081/ejh.2024.4019
    1720
    PDF: 521
    HTML: 16
  • Can the AGE/RAGE/ERK signalling pathway and the epithelial-to-mesenchymal transition interact in the pathogenesis of chronic rhinosinusitis with nasal polyps?

    Antonella Vetuschi, Simon Pompili, Gian Piero Di Marco, Federico Calvaruso, Enz Iacomino, Lidia Angelosante, Claudio Festuccia, Alessandro Colapietro, Roberta Sferra
    23-01-2020
    https://doi.org/10.4081/ejh.2020.3079
    2023
    PDF: 1151
    HTML: 15
  • Investigation of seasonal changes in lipid synthesis and metabolism-related genes in the oviduct of Chinese brown frog (Rana dybowskii)

    Yankun Wang, Yuning Liu, Yawei Wang, Ao Zhang, Wenqian Xie, Haolin Zhang, Qiang Weng, Meiyu Xu
    20-12-2023
    https://doi.org/10.4081/ejh.2023.3890
    1148
    PDF: 612
    HTML: 19
  • Porphyromonas gingivalis lipopolysaccharide stimulation in human periodontal ligament stem cells: role of epigenetic modifications to the inflammation

    Francesca Diomede, Soundara Rajan Thangavelu, Ilaria Merciaro, Monica D'Orazio, Placido Bramanti, Emanuela Mazzon, Oriana Trubiani
    25-08-2017
    https://doi.org/10.4081/ejh.2017.2826
    2978
    PDF: 1239
    HTML: 136
  • Forever particles: histochemistry in the plasticene age

    Beatrice Camia, Andrea Casasco, Manuela Monti
    01-08-2025
    https://doi.org/10.4081/ejh.2025.4226
    794
    PDF: 415
    HTML: 38
  • Pre-treatment with galectin-1 attenuates lipopolysaccharide-induced myocarditis by regulating the Nrf2 pathway

    Liying Shen, Kongjie Lu, Zhenfeng Chen, Yingwei Zhu, Cong Zhang, Li Zhang
    07-12-2023
    https://doi.org/10.4081/ejh.2023.3816
    1073
    PDF: 634
    HTML: 26
  • Astragaloside IV augments anti-PD-1 therapy to suppress tumor growth in lung cancer by remodeling the tumor microenvironment

    Tao Wu, Shikui Wu, Hui Gao, Haolei Liu, Jun Feng, Ge Yin
    23-10-2024
    https://doi.org/10.4081/ejh.2024.4098
    2040
    PDF: 395
    HTML: 17
  • Histopathological and immunofluorescent characterization of post-sepsis immune dysregulation in a clinically relevant mouse model

    Haoran Tang, Chen Liao, Ning Tang, Hui Li, Yi Liu, Lingling Wang, Zongfang Ren
    12-02-2026
    https://doi.org/10.4081/ejh.2026.4435
    299
    PDF: 239
    HTML: 4
  • Ghrelin reduces cerebral ischemic injury in rats by reducing M1 microglia/macrophages

    Rong Tian, Gengsheng Mao
    12-01-2022
    https://doi.org/10.4081/ejh.2022.3350
    1723
    PDF: 835
    HTML: 35
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Vol. 70 No. 1 (2026)
Low ozone concentrations promote in vitro preservation of explanted articular cartilage: an ultrastructural study
Giada Remoli et al.
26 January 2026
Vol. 70 No. 1 (2026)
Overexpression of GPER1 suppressed esophageal carcinoma growth via activating cAMP pathway
Hongmei Yin et al.
26 January 2026

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European Journal of Histochemistry

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