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  Toll-like receptor 4 expression in the epithelium of inflammatory periapical lesions. An immunohistochemical study

  R. Leonardi, R.E. Perrotta, C. Loreto, G. Musumeci, S. Crimi, J.N. dos Santos, M.C. Rusu, P. Bufo, E. Barbato, G. Pannone

  26-10-2015

  https://doi.org/10.4081/ejh.2015.2547

  1797

  PDF: 1033

  HTML: 352
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  Dexmedetomidine attenuates neuroinflammation and microglia activation in LPS-stimulated BV2 microglia cells through targeting circ-Shank3/miR-140-3p/TLR4 axis

  Guangbao He, Yibo He, Hongwei Ni, Kai Wang, Yijun Zhu, Yang Bao

  26-07-2023

  https://doi.org/10.4081/ejh.2023.3766

  1822

  PDF: 1184

  HTML: 14
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  Mucin1 relieves acute lung injury by inhibiting inflammation and oxidative stress

  Chunlin Ye, Bin Xu, Jie Yang, Yunkun Liu, Zhikai Zeng, Lingchun Xia, Quanjin Li, Guowen Zou

  02-12-2021

  https://doi.org/10.4081/ejh.2021.3331

  2460

  PDF: 1414

  HTML: 37
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  MyD88/ERK/NFkB pathways and pro-inflammatory cytokines release in periodontal ligament stem cells stimulated by Porphyromonas gingivalis

  Francesca Diomede, Maria Zingariello, Marcos F.X.B. Cavalcanti, Ilaria Merciaro, Jacopo Pizzicannella, Natalia de Isla, Sergio Caputi, Patrizia Ballerini, Oriana Trubiani

  24-05-2017

  https://doi.org/10.4081/ejh.2017.2791

  3141

  PDF: 1342

  HTML: 149
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  Effects of piperlonguminine on lung injury in severe acute pancreatitis via the TLR4/NF-κB pathway

  Qian Hu, Ran Tao, Xiaoyun Hu, Haibo Wu, Jianjun Xu

  20-03-2023

  https://doi.org/10.4081/ejh.2023.3639

  1150

  PDF: 682

  HTML: 22
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  Pretreatment with geniposide mitigates myocardial ischemia/reperfusion injury by modulating inflammatory response through TLR4/NF-κB pathway

  Yanmei Yao, Leqing Lin, Wenxue Tang, Yueliang Shen, Fayu Chen, Ning Li, Baiyong Wang

  08-09-2023

  https://doi.org/10.4081/ejh.2023.3742

  1026

  PDF: 448

  HTML: 19
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  Inhibition of HMGB1 suppresses inflammation and catabolism in temporomandibular joint osteoarthritis via NF-κB signaling pathway

  Yan Yan Li, Ya Ping Feng, Li Liu, Jin Ke, Xing Long

  21-06-2022

  https://doi.org/10.4081/ejh.2022.3357

  1659

  PDF: 1066

  HTML: 26

• Propofol alleviates M1 polarization and neuroinflammation of microglia in a subarachnoid hemorrhage model in vitro, by targeting the miR-140-5p/TREM-1/NF-κB signaling axis

  Lan Wang, Zhenyu Fan, Haijin Wang, Shougui Xiang

  17-09-2024

  https://doi.org/10.4081/ejh.2024.4034

  1079

  PDF: 517

  HTML: 9
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  Polydatin reverses oxidation low lipoprotein (oxLDL)-induced apoptosis of human umbilical vein endothelial cells via regulating the miR-26a-5p/BID axis

  Dajie Wang, Zhaofeng Zhou, Liang Yuan

  20-09-2022

  https://doi.org/10.4081/ejh.2022.3505

  1225

  PDF: 573

  HTML: 37
• 

  DNMT1 regulates IL-6- and TGF-β1-induced epithelial mesenchymal transition in prostate epithelial cells

  Hui Xu, Yanbo Chen, Qi Chen, Huan Xu, Yanxia Wang, Jiao Yu, Juan Zhou, Zhong Wang, Bing Xu

  03-05-2017

  https://doi.org/10.4081/ejh.2017.2775

  2643

  PDF: 975

  HTML: 171
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  Effects of miR-939 and miR-376A on ulcerative colitis using a decoy strategy to inhibit NF-κB and NFAT expression

  Yongwei Lin, Zhipeng Zhou, Lang Xie, Yongsheng Huang, Zhenghua Qiu, Lili Ye, Chunhui Cui

  15-02-2022

  https://doi.org/10.4081/ejh.2022.3316

  1795

  PDF: 711

  HTML: 24
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  Study on the mechanism of Shenling Baizhu powder on the pathogenesis of pregnancy complicated with non-alcoholic fatty liver, based on PI3K/AKT/mTOR signal pathway

  Yao Le, Zhijun Wang, Qian Zhang, Ling Miao, Xiaohong Wang, Guorong Han

  17-09-2024

  https://doi.org/10.4081/ejh.2024.4093

  2166

  PDF: 547

  HTML: 42
• 

  ECRG4 expression in normal rat tissues: expression study and literature review

  A. Porzionato, M. Rucinski, V. Macchi, G. Sarasin, L.K. Malendowicz, R. De Caro

  18-05-2015

  https://doi.org/10.4081/ejh.2015.2458

  2876

  PDF: 1137

  Supplementary: 365

  HTML: 1013
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  circRNA-79530 regulates Twist-mediated mitochondrial damage via sponging miR-214 affecting hypoxia/reoxygenation-induced injury in H9c2 cardiomyocytes

  Ziyang Yu, Wenbo Xu, Yirong Teng, Tingting Li, Ren Guo, Ju Li, Xichen Li, Yanping Li, Yinglu Hao

  22-08-2025

  https://doi.org/10.4081/ejh.2025.4230

  327

  PDF: 249

  HTML: 4
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  Investigation of seasonal changes in lipid synthesis and metabolism-related genes in the oviduct of Chinese brown frog (Rana dybowskii)

  Yankun Wang, Yuning Liu, Yawei Wang, Ao Zhang, Wenqian Xie, Haolin Zhang, Qiang Weng, Meiyu Xu

  20-12-2023

  https://doi.org/10.4081/ejh.2023.3890

  1182

  PDF: 622

  HTML: 22
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  Porphyromonas gingivalis lipopolysaccharide stimulation in human periodontal ligament stem cells: role of epigenetic modifications to the inflammation

  Francesca Diomede, Soundara Rajan Thangavelu, Ilaria Merciaro, Monica D'Orazio, Placido Bramanti, Emanuela Mazzon, Oriana Trubiani

  25-08-2017

  https://doi.org/10.4081/ejh.2017.2826

  3009

  PDF: 1255

  HTML: 136
• 

  Forever particles: histochemistry in the plasticene age

  Beatrice Camia, Andrea Casasco, Manuela Monti

  01-08-2025

  https://doi.org/10.4081/ejh.2025.4226

  839

  PDF: 431

  HTML: 41
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  Pre-treatment with galectin-1 attenuates lipopolysaccharide-induced myocarditis by regulating the Nrf2 pathway

  Liying Shen, Kongjie Lu, Zhenfeng Chen, Yingwei Zhu, Cong Zhang, Li Zhang

  07-12-2023

  https://doi.org/10.4081/ejh.2023.3816

  1106

  PDF: 661

  HTML: 28
• 

  Astragaloside IV augments anti-PD-1 therapy to suppress tumor growth in lung cancer by remodeling the tumor microenvironment

  Tao Wu, Shikui Wu, Hui Gao, Haolei Liu, Jun Feng, Ge Yin

  23-10-2024

  https://doi.org/10.4081/ejh.2024.4098

  2097

  PDF: 419

  HTML: 24
• 

  Histopathological and immunofluorescent characterization of post-sepsis immune dysregulation in a clinically relevant mouse model

  Haoran Tang, Chen Liao, Ning Tang, Hui Li, Yi Liu, Lingling Wang, Zongfang Ren

  12-02-2026

  https://doi.org/10.4081/ejh.2026.4435

  365

  PDF: 286

  HTML: 4
• 

  Ghrelin reduces cerebral ischemic injury in rats by reducing M1 microglia/macrophages

  Rong Tian, Gengsheng Mao

  12-01-2022

  https://doi.org/10.4081/ejh.2022.3350

  1747

  PDF: 852

  HTML: 36
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  Placental mesenchymal stem cell exosomes drive macrophage M2 polarization via the miR-146a-5p/TRAF6 axis to ameliorate preeclampsia

  Xiaoli Liu, Ruiyue Li, Junjie Sun, Yuanpei Yang, Lina Hu

  17-11-2025

  https://doi.org/10.4081/ejh.2025.4426

  667

  PDF: 397

  HTML: 14

• P52 | MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL EVALUATION OF THE ANTI-INFLAMMATORY AND ANTIOXIDANT PROPERTIES OF HEMP EXTRACTS ON THE LIVER OF RATS INVOLVED IN INFLAMMATION CAUSED BY LPS A. Miller¹, M. Kotanska², M. Bednarski², G.P. Lombardo³, V. Natale³, G. Pirracchio³, L. Spiccia³, S. Pergolizzi³, G. Rizzo⁴, E.R. Lauriano³ | ¹Department of Veterinary Sciences, University of Messina, Messina, Italy; ²Department of Pharmacological Screening, Jagiellonian University Medical College, Kraków, Poland: ³Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina, Italy; ⁴Department of Clinical and Experimental Medicine, University of Messina, Italy

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4374

  257
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  Sodium hyaluronate promotes proliferation, autophagy, and migration of corneal epithelial cells by downregulating miR-18a in the course of corneal epithelial injury

  Yingzhuo Guo, Hua Wang

  15-06-2023

  https://doi.org/10.4081/ejh.2023.3663

  1239

  PDF: 588

  Supplementary: 103

  HTML: 23
• 

  Low ozone concentrations stimulate cytoskeletal organization, mitochondrial activity and nuclear transcription

  M. Costanzo, B. Cisterna, A. Vella, T. Cestari, V. Covi, G. Tabaracci, M. Malatesta

  21-04-2015

  https://doi.org/10.4081/ejh.2015.2515

  3009

  PDF: 978

  HTML: 408

• Deubiquitinase USP14 is upregulated in Crohn's disease and inhibits the NOD2 pathway mediated inflammatory response in vitro

  Mengling Li, Yan Zhao, Jiayi Zhang, Wang Jiang, Siyuan Peng, Jinyue Hu, Yueming Shen

  09-09-2024

  https://doi.org/10.4081/ejh.2024.4101

  1188

  PDF: 399

  HTML: 10
• 

  From the intestinal mucosal barrier to the enteric neuromuscular compartment: an integrated overview on the morphological changes in Parkinson’s disease

  Carolina Pellegrini, Vanessa D'Antongiovanni, Chiara Ippolito, Cristina Segnani, Luca Antonioli, Matteo Fornai, Nunzia Bernardini

  22-11-2021

  https://doi.org/10.4081/ejh.2021.3278

  1412

  PDF: 814

  HTML: 38

• P74 | EXPRESSION OF PISCIDIN, TLR-4, ERK2 AND P-P38 MAPK IN THE ZEBRAFISH GUT EXPOSED TO PCB-126 AND POSSIBLE PROTECTIVE EFFECTS OF GINESTEIN L. Spiccia¹, A. Miller², G.P. Lombardo¹, V. Natale¹, F. Pellicanò¹, S. Marino¹, A. Nunnari¹, A. Migliorato³, E.R. Laurian¹ | ¹Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina, Italy; ²Department of Veterinary Sciences, University of Messina, Messina, Italy; ³Department of Biomedical and Dental Sciences and Morphofunctional Images, University of Messina, Messina, Italy

  21-08-2025

  https://doi.org/10.4081/ejh.2025.4399

  224

• Pretreatment with interleukin-15 attenuates inflammation and apoptosis by inhibiting NF-κB signaling in sepsis-induced myocardial dysfunction

  Chaojie He, Yi Yu, Feifan Wang, Wudi Li, Hui Ni, Meixiang Xiang

  29-04-2024

  https://doi.org/10.4081/ejh.2024.4019

  1765

  PDF: 548

  HTML: 17
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  Can the AGE/RAGE/ERK signalling pathway and the epithelial-to-mesenchymal transition interact in the pathogenesis of chronic rhinosinusitis with nasal polyps?

  Antonella Vetuschi, Simon Pompili, Gian Piero Di Marco, Federico Calvaruso, Enz Iacomino, Lidia Angelosante, Claudio Festuccia, Alessandro Colapietro, Roberta Sferra

  23-01-2020

  https://doi.org/10.4081/ejh.2020.3079

  2042

  PDF: 1174

  HTML: 16