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ASTROCYTE DYSFUNCTION IN AUTOSOMAL DOMINANT LEUKODYSTROPHY (ADLD): INSIGHTS FROM 2D AND 3D IN VITRO SYSTEMS AND EX VIVO CEREBROSPINAL FLUID METABOLOMICS F.D. Koufi1, V. Righi2, A. Mucci3, I. Rusciano1, S. Mongiorgi1, M. Shin4, Y. Kosodo4, I. Cani5, P. Cortelli6, E. Giorgio7, G. Ramazzotti1, L. Manzoli1, S. Ratti1 | 1 Cellular Signaling Laboratory, Anatomy Center, Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy; 2Department of Life Quality Studies, University of Bologna, Campus of Rimini, Rimini, Italy; 3Department of Geological and Chemical Sciences, University of Modena and Reggio Emilia, Modena, Italy; 4Korea Brain Research Institute (KBRI), Daegu, Republic of Korea; 5Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy; 6IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy; 7Department of Molecular Medicine, University of Pavia, Pavia, Italy; Medical Genetics Unit, IRCCS Mondino Foundation, Pavia, Italy.
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THE DUAL EFFECT OF CADMIUM IN ASTROCYTE PHYSIOLOGY: FROM ADAPTIVE ACTIVATION TO POTENTIAL NEUROTOXICITY Branca JJV, Guarnieri G, Mencarelli F, Gulisano M, Morelli A and Pacini A | Department of Experimental and Clinical Medicine, Anatomy and Histology Section, University of Firenze, Firenze, Italy
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Antigen retrieval pre-treatment causes a different expression pattern of Cav3.2 in rat and mouse spinal dorsal horn
2187PDF: 960Supplementary: 265HTML: 50 -
Effects of cadmium on the glial architecture in lizard brain
3184PDF: 851HTML: 376 -
73 | PROTECTIVE ROLE FOR OLEOYLETHANOLAMIDE IN THE HUMAN BRAIN: EFFECTS ON THE MODULATION OF NEUROINFLAMMATION AND INSULIN RESISTANCE IN HUMAN ASTROCYTES Lucia Sileo1, Giulia Scanavino1, Silvana Gaetani2, Ada MariaTata1 | 1Dept. of Biology and Biotechnologies "Charles Darwin", University of Rome "Sapienza", Rome, Italy; 2Dept. of Physiology and Pharmacology “Vittorio Erspamer”, University of Rome "Sapienza", Rome, Italy
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MODULATION OF EXTRACELLULAR SIGNAL-RELATED KINASE, CYCLIN D1, GLIAL FIBRILLARY ACIDIC PROTEIN, AND VIMENTIN EXPRESSION IN ESTRADIOL-PRETREATED ASTROCYTE CULTURES TREATED WITH COMPETENCE AND PROGRESSION GROWTH FACTORS Barbagallo A1, Barbagallo F1, Rapisarda G1 and Avola R1 | 1Department of Biometec (Biochemistry Section), University of Catania, Italy
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3-hydroxi-anthranilic acid is early expressed in stroke
2456PDF: 768HTML: 320 -
67 | DYNAMICS AND INTRACELLULAR TRAFFICKING OF M2R-DUALSTERIC AGONIST COMPLEX INTO GLIOBLASTOMA CELLS G. Scanavino1, C. Metelli1, L. Sileo1, C. Dallanoce2, Matera2, AM. Tata1 | 1Dept. of Biology and Biotechnology, University of Rome “Sapienza”, Italy; 2Dept. of Pharmaceutical Sciences, University of Milan, Italy
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MORPHOLOGICAL AND SYNAPTIC CHANGES OF THE CORTICAL GABAERGIC INHIBITORY SYSTEM IN SPINAL MUSCULAR ATROPHY Menduti G1,2, Ferrini F3,4, Caretto A1,2, Hassan A5,6, di Vito R6,7, Beltrando G1,2, Marnetto D2, Usiello A6,7, Di Cunto F1,2, Boido M1,2, and Vercelli A1,2 | 1Neuroscience Institute Cavalieri Ottolenghi, Orbassano, Turin, Italy; 2Department of Neuroscience «Rita Levi Montalcini», University of Turin, Italy; 3Department of Veterinary Sciences, University of Turin, Grugliasco, Turin, Italy; 4Department of Psychiatry and Neuroscience, Université Laval, Québec, Canada; 5European School of Molecular medicine, University of Milan, Italy; 6Laboratory of Translational Neuroscience, Ceinge Biotecnologie Avanzate, Naples, Italy; 7Department of Environmental, Biological and Pharmaceutical Science and Technologies, Università degli Studi della Campania Luigi Vanvitelli, Caserta, Italy
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CHANGE IN AQUAPORIN-4 EXPRESSION AND LOCALIZATION DURING AMYOTROPHIC LATERAL SCLEROSIS AND SPINAL MUSCULAR ATROPHY PROGRESSION Tuninetti A1, Boido M1, Vercelli A1 and Pacca P1 | 1Department of Neuroscience “Rita Levi Montalcini”, Neuroscience Institute Cavalieri Ottolenghi, University of Turin, Italy
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Forever particles: histochemistry in the plasticene age
1587PDF: 705HTML: 69 -
UNRAVELING GLIAL REMODELING IN SPACE AND TIME DURING GLIOBLASTOMA EVOLUTION Riccio L1, De Luca C1, Rega C1, Papa M1 and Virtuoso A1 | 1Laboratory of Neuronal Networks Morphology and System Biology, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy
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HUMAN INDUCED PLURIPOTENT STEM CELLS-DERIVED CEREBRAL ORGANOIDS AS A MODEL FOR C9ORF72-LINKED FRONTO-TEMPORAL DEMENTIA: INSIGHTS INTO NEURONAL AND GLIAL DIFFERENTIATION DYNAMICS Ferrero C1,2,3, Pacca P1,2, Vercelli A1,2 and Boido M1,2 | 1Department of Neuroscience “Rita Levi Montalcini”, University of Turin, Italy; 2Neuroscience Institute Cavalieri Ottolenghi, Italy 3University School for Advanced Studies IUSS Pavia, Pavia, Italy
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