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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

1.9
Impact Factor 2025
3.7
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1.9
Impact Factor 2025
3.7
CiteScore 2025
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  • Senescence-associated ß-galactosidase staining over the lifespan differs in a short- and a long-lived fish species

    Simon Schöfer, Sylvia Laffer, Stefanie Kirchberger, Michael Kothmayer, Renate Löhnert, Elmar E. Ebner, Klara Weipoltshammer, Martin Distel, Oliver Pusch, Christian Schöfer
    29-02-2024
    https://doi.org/10.4081/ejh.2024.3977
    2282
    PDF: 1204
    Supplementary: 111
    HTML: 174
  • Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells

    Huina Su, Ruiqiong Ma, Dehui Su, Cheng Tan, Ye Zhu, Xin Yang
    21-04-2026
    https://doi.org/10.4081/ejh.2026.4537
    757
    PDF: 483
    HTML: 11
  • Ferroptosis resistance cooperates with cellular senescence in the overt stage of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

    Antonella Vetuschi, Alfredo Cappariello, Paolo Onori, Eugenio Gaudio, Giovanni Latella, Simona Pompili, Roberta Sferra
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3391
    3940
    PDF: 1942
    HTML: 61
  • Premature senescence in primary muscle cultures of myotonic dystrophy type 2 is not associated with p16 induction

    L.V. Renna, R. Cardani, A. Botta, G. Rossi, B. Fossati, E. Costa, G. Meola
    22-10-2014
    https://doi.org/10.4081/ejh.2014.2444
    2457
    PDF: 1103
    HTML: 509
  • <a href="https://it.freepik.com/vettori/sfondo">Sfondo vettore creata da pikisuperstar - it.freepik.com</a>

    DNA damage and repair in differentiation of stem cells and cells of connective cell lineages: A trigger or a complication?

    Nikolajs Sjakste, Una Riekstiņa
    03-05-2021
    https://doi.org/10.4081/ejh.2021.3236
    3292
    PDF: 1417
    HTML: 88
  • Autophagic processes increase during senescence in cultured sheep neurons and astrocytes

    Vittorio Farina, Gianluca Lepore, Francesca Biagi, Marcella Carcupino, Marco Zedda
    03-04-2018
    https://doi.org/10.4081/ejh.2018.2891
    2465
    PDF: 698
    HTML: 25
  • Lectin-like, oxidized low-density lipoprotein receptor-1-deficient mice show resistance to age-related knee osteoarthritis

    Kazuhiko Hashimoto, Yutaka Oda, Fumihisa Nakamura, Ryosuke Kakinoki, Masao Akagi
    14-02-2017
    https://doi.org/10.4081/ejh.2017.2762
    3045
    PDF: 963
    HTML: 252
  • Nuclear damages and oxidative stress: new perspectives for laminopathies

    G. Lattanzi, S. Marmiroli, A. Facchini, N.M. Maraldi
    e45
    18-10-2012
    https://doi.org/10.4081/ejh.2012.e45
    2103
    PDF: 941
    HTML: 206
  • By Dchordpdx - Own work, CC BY 4.0, https://commons.wikimedia.org/w/index.php?curid=64427063

    Quantitative, structural and molecular changes in neuroglia of aging mammals: A review

    Ennio Pannese
    23-06-2021
    https://doi.org/10.4081/ejh.2021.3249
    1779
    PDF: 869
    HTML: 18
  • ECRG4 expression in normal rat tissues: expression study and literature review

    A. Porzionato, M. Rucinski, V. Macchi, G. Sarasin, L.K. Malendowicz, R. De Caro
    18-05-2015
    https://doi.org/10.4081/ejh.2015.2458
    3093
    PDF: 1187
    Supplementary: 393
    HTML: 1018
  • Cultured myoblasts from patients affected by myotonic dystrophy type 2 exhibit senescence-related features: ultrastructural evidence

    M. Malatesta, M. Giagnacovo, L.V. Renna, R. Cardani, G. Meola, C. Pellicciari
    e26
    21-09-2011
    https://doi.org/10.4081/ejh.2011.e26
    2213
    PDF: 778
  • The hematopoietic stem cells supportive megakaryocytes as shapers of the bone marrow niche

    Francesca Arciprete, Viola Velardi, Paola Verachi, Claudio Carta, Antonio Di Virgilio, Vincenzo Roberti, Giorgio Vivacqua, Rosalba Rana, Maria Zingariello
    16-12-2025
    https://doi.org/10.4081/ejh.2025.4424
    940
    PDF: 307
    HTML: 16
  • Immunofluorescent localization of ubiquitin and proteasomes in nucleolar vacuoles of soybean root meristematic cells

    D. Stępiński
    e13
    30-05-2012
    https://doi.org/10.4081/ejh.2012.13
    1196
    PDF: 476
    HTML: 1793
  • Immunohistochemical detection of putative pathogenetic factors in adhesions of infants: a pilot study

    Arvis Pauliņš, Anna Junga, Māra Pilmane
    10-02-2026
    https://doi.org/10.4081/ejh.2026.4438
    285
    PDF: 385
    HTML: 9
  • Impact of Histochemistry on biomedical research: looking through the articles published in a long-established histochemical journal

    C. Pellicciari
    30-12-2014
    https://doi.org/10.4081/ejh.2014.2474
    2428
    PDF: 698
    HTML: 823
  • Luminescence and fluorescence of essential oils. Fluorescence imaging in vivo of wild chamomile oil

    F. Boschi, M. Fontanella, L. Calderan, A. Sbarbati
    e18
    16-06-2011
    https://doi.org/10.4081/ejh.2011.e18
    1290
    PDF: 964
    HTML: 1519
  • Overexpression of hsa_circ_0001861 inhibits pulmonary fibrosis through targeting miR-296-5p/BCL-2 binding component 3 axis

    Tao Wu, Shikui Wu, Hailu Jiao, Jun Feng, Xiang Zeng
    02-10-2023
    https://doi.org/10.4081/ejh.2023.3839
    1485
    PDF: 836
    HTML: 40
  • Nuclear factor-kB and nitric oxide synthases in red blood cells: good or bad in obesity? A preliminary study

    Monika Široká, Caterina Franco, Zuzana Guľašová, Zdenka Hertelyová, Vladimíra Tomečková, Luigi F. Rodella, Rita Rezzani
    21-01-2020
    https://doi.org/10.4081/ejh.2020.3081
    1820
    PDF: 866
    HTML: 19
  • The expression of Sirtuins 1 and 4 in peripheral blood leukocytes from patients with type 2 diabetes

    R. Song, W. Xu, Y. Chen, Z. Li, Y. Zeng, Y. Fu
    e10
    21-03-2011
    https://doi.org/10.4081/ejh.2011.e10
    2087
    PDF: 675
    HTML: 950
  • Is there still room for novelty, in histochemical papers?

    Carlo Pellicciari
    16-12-2016
    https://doi.org/10.4081/ejh.2016.2758
    2920
    PDF: 727
    HTML: 283
  • LOX-1 deficient mice show resistance to zymosan-induced arthritis

    Kazuhiko Hashimoto, Yutaka Oda, Koichi Nakagawa, Terumasa Ikeda, Kazuhiro Ohtani, Masao Akagi
    22-01-2018
    https://doi.org/10.4081/ejh.2018.2847
    2117
    PDF: 900
    HTML: 83
  • Expression and role of cocaine-amphetamine regulated transcript (CART) in the proliferation of biliary epithelium

    Arianna Casini, Giorgio Vivacqua, Rosa Vaccaro, Anastasia Renzi, Stefano Leone, Luigi Pannarale, Antonio Franchitto, Paolo Onori, Romina Mancinelli, Eugenio Gaudio
    19-10-2023
    https://doi.org/10.4081/ejh.2023.3846
    1798
    PDF: 666
    HTML: 33
  • Histochemistry as an irreplaceable approach for investigating functional cytology and histology

    C. Pellicciari
    e41
    19-12-2013
    https://doi.org/10.4081/ejh.2013.e41
    3420
    PDF: 911
    HTML: 409
  • A journal of histochemistry as a forum for non-histochemical scientific societies

    Carlo Pellicciari, Marco Biggiogera, Manuela Malatesta
    23-12-2019
    https://doi.org/10.4081/ejh.2019.3106
    1959
    PDF: 509
    HTML: 43
  • p53 and telomerase control rat myocardial tissue response to hypoxia and ageing

    A. Cataldi, S. Zara, M. Rapino, M. Zingariello, V. di Giacomo, A. Antonucci
    e25
    09-12-2009
    https://doi.org/10.4081/ejh.2009.e25
    1426
    PDF: 790
  • Muscleblind-like1 undergoes ectopic relocation in the nuclei of skeletal muscles in myotonic dystrophy and sarcopenia

    M. Malatesta, M. Giagnacovo, M. Costanzo, B. Cisterna, R. Cardani, G. Meola
    e15
    22-04-2013
    https://doi.org/10.4081/ejh.2013.e15
    2982
    PDF: 4336
    HTML: 469
  • Morphological and ultrastructural analysis of normal, injured and osteoarthritic human knee menisci

    Michela Battistelli, Marta Favero, Debora Burini, Giovanni Trisolino, Dante Dallari, Lucia De Franceschi, Steven R. Goldring, Mary B. Goldring, Elisa Belluzzi, Giuseppe Filardo, Brunella Grigolo, Elisabetta Falcieri, Eleonora Olivotto
    11-02-2019
    https://doi.org/10.4081/ejh.2019.2998
    2758
    PDF: 1360
    Supplementary: 243
    HTML: 56
  • The histochemical profile of the rat extensor digitorum longus muscle differentiates after birth and dedifferentiates in senescence

    M Lehnert, H Laurer, B Maier, J Frank, I Marzi, W-I Steudel, A Mautes
    111-118
    10-08-2009
    https://doi.org/10.4081/1132
    571
    PDF: 466
  • 1954-2024: 70 years of histochemical research with the European Journal of Histochemistry

    Carlo Pellicciari, Marco Biggiogera, Manuela Malatesta
    29-01-2024
    https://doi.org/10.4081/ejh.2024.3970
    1288
    PDF: 447
    HTML: 13
  • LncRNA GClnc1 may contribute to the progression of ovarian cancer by regulating p53 signaling pathway

    Hu Li, Zheng Zeng, Xiang Yang, Ye Chen, Lei He, Ting Wan
    10-11-2020
    https://doi.org/10.4081/ejh.2020.3166
    1046
    PDF: 663
    HTML: 20
  • GLIAL INFLAMMASOME ACTIVATION AND BLOOD-BRAIN BARRIER BREAKDOWN IN AGE-RELATED NEURODEGENERATION Errede M1, Girolamo F1, d’Amati A1,2, de Giorgis M1, Lorusso L1, Pierucci C3, Bernardini N3, Pellegrini C3, Virgintino D1 and Annese T2 | 1University of Bari, Department of Translational Biomedicine and Neuroscience – Human Anatomy and Histology Unit, Bari, Italy; 2Libera Università del Mediterraneo (LUM) Giuseppe Degennaro University, Department of Medicine and Surgery, Bari, Italy; 3University of Pisa, Department of Clinical and Experimental Medicine - Unit of Histology and Medical Embryology, Pisa, Italy

    12-12-2025
    https://doi.org/10.4081/ejh.2025.4460
    490
  • Histochemistry for nucleic acid research: 60 years in the European Journal of Histochemistry

    Claudio Casali, Stella Siciliani, Lorena Zannino, Marco Biggiogera
    20-04-2022
    https://doi.org/10.4081/ejh.2022.3409
    1850
    PDF: 948
    HTML: 31
  • Immunohistochemical study of doublecortin and nucleostemin in canine brain

    E. De Nevi, P. Marco-Salazar, D. Fondevila, E. Blasco, L. Pérez, M. Pumarola
    e9
    20-03-2013
    https://doi.org/10.4081/ejh.2013.e9
    2643
    PDF: 740
    HTML: 283
  • Ultrastructural histochemistry in biomedical research: Alive and kicking

    Manuela Malatesta
    07-11-2018
    https://doi.org/10.4081/ejh.2018.2990
    1993
    PDF: 725
    HTML: 31
  • Twenty years of histochemistry in the third millennium, browsing the scientific literature

    Carlo Pellicciari
    29-12-2020
    https://doi.org/10.4081/ejh.2020.3213
    1415
    PDF: 546
    HTML: 15
  • Aortic dissection is associated with reduced polycystin-1 expression, an abnormality that leads to increased ERK phosphorylation in vascular smooth muscle cells

    J. Feng, S. Ge, L. Zhang, H. Che, C. Liang
    16-12-2016
    https://doi.org/10.4081/ejh.2016.2711
    2659
    PDF: 1142
    HTML: 312
  • Expression of Ser729 phosphorylated PKCepsilon in experimental crescentic glomerulonephritis: an immunohistochemical study

    V.N. Karavana, H. Gakiopoulou, E.A. Lianos
    15-04-2014
    https://doi.org/10.4081/ejh.2014.2308
    2241
    PDF: 933
    HTML: 647
  • THE CHEMISTRY OF NUTRACEUTICALS: DRIVING HEALTH INNOVATIONS AND SHAPING NEW PARADIGMS M. Micucci | Department of Biomolecular Sciences, Urbino University “Carlo Bo”, Urbino, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4317
    243
  • The clinical significance of UBE2C gene in progression of renal cell carcinoma

    Zhiping Chen, Lanfeng Wang
    29-03-2021
    https://doi.org/10.4081/ejh.2021.3196
    1944
    PDF: 906
    HTML: 31
  • On the future contents of a small journal of histochemistry

    C. Pellicciari
    e51
    10-12-2012
    https://doi.org/10.4081/ejh.2012.e51
    2578
    PDF: 987
    HTML: 942
  • Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model

    Juan Fan, Yu Ma, Liying Sun, Suhua Miao, Jianghong He
    20-04-2026
    https://doi.org/10.4081/ejh.2026.4533
    453
    PDF: 260
    HTML: 14
  • Developmental immunolocalization of the Klotho protein in mouse kidney epithelial cells

    J.H. Song, M.Y. Lee, Y.J. Kim, S.R. Park, J. Kim, S.Y. Ryu, J.Y. Jung
    24-01-2014
    https://doi.org/10.4081/ejh.2014.2256
    3791
    PDF: 939
    HTML: 510
  • Immuno- and glyco-histochemistry as a tool to evaluate the oregano supplemented feed effects in pig gut

    Cecilia Dall'Aglio, Francesca Mercati, Valerio Faeti, Gabriele Acuti, Massimo Trabalza Marinucci, Elena De Felice, Federico Maria Tardella, Maria Pia Franciosini, Patrizia Casagrande Proietti, Daniele Catorci, Paolo Stacchini, Augusto Pastorelli, Paola Scocco
    20-02-2020
    https://doi.org/10.4081/ejh.2020.3110
    1831
    PDF: 850
    Supplementary: 203
    HTML: 16
  • Structural and functional alterations of the cell nucleus in skeletal muscle wasting: the evidence in situ

    M. Malatesta, G. Meola
    e44
    19-10-2010
    https://doi.org/10.4081/ejh.2010.e44
    1566
    PDF: 623
    HTML: 620
  • P13 | MORPHO-FUNCTIONAL DIFFERENCES IN THE GUT OF AGED MICE WITH THE POSSIBLE EFFECTS OF ANTI-INFLAMMATORY TREATMENTS A. Casini1, S. Leone1, R. Mancinelli1, R. Vaccaro1, M. Catalano2, G. D’Alessandro2, A. Rinaldi2, A. Reccagni2, G. Vivacqua3, A. Franchitto4, P. Onori1, C. Limatola2, E. Gaudio1 | 1Department of Anatomical, Histological, Forensic Medicine and Orthopaedics Sciences, Sapienza University of Rome, Italy; 2Department of Physiology and Pharmacology, Sapienza University of Rome, Italy; 3Department of Medicine and Surgery, University Campus BioMedico of Rome, Italy; 4Department of Movement, Human and Health Sciences, Division of Health Sciences, University of Rome «Foro Italico», Rome,Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4333
    170
  • Tibialis anterior muscle needle biopsy and sensitive biomolecular methods: a useful tool in myotonic dystrophy type 1

    S. Iachettini, R. Valaperta, A. Marchesi, A. Perfetti, G. Cuomo, B. Fossati, L. Vaienti, E. Costa, G. Meola, R. Cardani
    26-10-2015
    https://doi.org/10.4081/ejh.2015.2562
    2069
    PDF: 954
    HTML: 394
  • Ultrastructural immunocytochemistry shows impairment of RNA pathways in skeletal muscle nuclei of old mice: A link to sarcopenia?

    Maria Assunta Lacavalla, Barbara Cisterna, Carlo Zancanaro, Manuela Malatesta
    24-03-2021
    https://doi.org/10.4081/ejh.2021.3229
    2112
    PDF: 736
    HTML: 21
  • Skeletal muscle features in myotonic dystrophy and sarcopenia: do similar nuclear mechanisms lead to skeletal muscle wasting?

    M. Malatesta
    e36
    10-08-2012
    https://doi.org/10.4081/ejh.2012.e36
    1762
    PDF: 944
  • The earthworm Dendrobaena veneta (Annelida): A new experimental-organism for photobiomodulation and wound healing

    Andrea Amaroli, Sara Ferrando, Marina Pozzolini, Lorenzo Gallus, Steven Parker, Stefano Benedicenti
    09-02-2018
    https://doi.org/10.4081/ejh.2018.2867
    2243
    PDF: 990
    HTML: 59
  • Therapeutic effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles on ovarian functions through the PI3K/Akt cascade in mice with premature ovarian failure

    Nan Li, Xue Fan, Lihong Liu, Yanbing Liu
    27-07-2023
    https://doi.org/10.4081/ejh.2023.3506
    1825
    PDF: 1112
    HTML: 25
  • Bradykinin and noradrenaline preconditioning influences level of antioxidant enzymes SOD, CuZn-SOD, Mn-SOD and catalase in the white matter of spinal cord in rabbits after ischemia/reperfusion

    Marianna Danková, Iveta Domoráková, Zuzana Fagová, Milan Stebnický, Alexandra Kunová, Eva Mechírová
    18-10-2019
    https://doi.org/10.4081/ejh.2019.3045
    1682
    PDF: 735
    HTML: 12
  • Histochemistry through the years, browsing a long-established journal: novelties in traditional subjects

    C. Pellicciari
    e51
    16-12-2010
    https://doi.org/10.4081/ejh.2010.e51
    1549
    PDF: 753
    HTML: 3896
  • Tanshinone IIA attenuates hepatic stellate cell activation, oxidative stress, and liver fibrosis by inhibiting YAP signaling

    Dan Wang, Qingquan Tan, Qing Zheng, Yanling Ma, Li Feng
    17-06-2025
    https://doi.org/10.4081/ejh.2025.4218
    1504
    PDF: 591
    HTML: 30
  • Histochemistry in biology and medicine: a message from the citing journals

    Carlo Pellicciari
    23-12-2015
    https://doi.org/10.4081/ejh.2015.2610
    3226
    PDF: 886
    HTML: 897
  • Comparison of CGRP distributions in the maxillary sinus and trigeminal ganglion between elderly dentulous and edentulous humans

    Hiroyuki Matsuda, Iwao Sato, Rieko Asaumi, Takuya Omotehara, Shinichi Kawata, Kenta Nagahori, Zhong-Lian Li, Masahiro Itoh
    31-03-2021
    https://doi.org/10.4081/ejh.2021.3234
    1980
    PDF: 695
    HTML: 29
  • Astragaloside IV inhibits nasopharyngeal carcinoma progression by inhibiting SATB2/Wnt/PD-L1 pathway and enhancing the killing activity of T cells

    Yinping Zeng, Jiajun Huang, Tingting Duan, Xiaofeng Wang
    28-05-2026
    https://doi.org/10.4081/ejh.2026.4540
    294
    PDF: 233
    HTML: 9
  • Protective effect of different antioxidant agents in UVB-irradiated keratinocytes

    Sara Salucci, Sabrina Burattini, Francesca Buontempo, Alberto Maria Martelli, Elisabetta Falcieri, Michela Battistelli
    18-09-2017
    https://doi.org/10.4081/ejh.2017.2784
    2529
    PDF: 1014
    HTML: 190
  • The Qi-Bang-Yi-Shen formula ameliorates renal dysfunction and fibrosis in rats with diabetic kidney disease via regulating PI3K/AKT, ERK and PPARγ signaling pathways

    Zhi Wang, Guihua Jian, Teng Chen, Yiping Chen, Junhui Li, Niansong Wang
    01-03-2023
    https://doi.org/10.4081/ejh.2023.3648
    4386
    PDF: 1097
    HTML: 45
  • Stem cells and aging - methods and protocols

    Carlo Alberto Redi
    br14
    01-10-2013
    https://doi.org/10.4081/ejh.2013.br14
    2204
    PDF: 442
  • Forever particles: histochemistry in the plasticene age

    Beatrice Camia, Andrea Casasco, Manuela Monti
    01-08-2025
    https://doi.org/10.4081/ejh.2025.4226
    1394
    PDF: 574
    HTML: 58
  • Autophagic degradation of farnesylated prelamin A as a therapeutic approach to lamin-linked progeria

    V. Cenni, C. Capanni, M. Columbaro, M. Ortolani, M.R. D'Apice, G. Novelli, M. Fini, S. Marmiroli, E. Scarano, N.M. Maraldi, S. Squarzoni, S. Prencipe, G. Lattanzi
    e36
    19-10-2011
    https://doi.org/10.4081/ejh.2011.e36
    2886
    PDF: 1083
  • The possible prognostic role of histone deacetylase and transforming growth factor β/Smad signaling in high grade gliomas treated by radio-chemotherapy: a preliminary immunohistochemical study

    Roberta Sferra, Simona Pompili, Claudio Festuccia, Francesco Marampon, Giovanni L. Gravina, Luca Ventura, Ernesto Di Cesare, Sara Cicchinelli, Eugenio Gaudio, Antonella Vetuschi
    16-05-2017
    https://doi.org/10.4081/ejh.2017.2732
    2737
    PDF: 1047
    HTML: 156
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
Nana Bao et al.
20 April 2026
Vol. 70 No. 2 (2026)
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells
Huina Su et al.
21 April 2026
Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

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