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P24 | DEVELOPMENT OF HEAD AND NECK SQUAMOUS CELL CARCINOMA PATIENT-DERIVED XENOGRAFTS (PDXS) AND ORGANOIDS (PDXOS) FOR MORPHOLOGICAL ANALYSIS AND DRUG SCREENING A. Francia1, C. Girone1, D.M. Filippini2, G. Querzoli3, M. Fermi4, S. Venturoli5, A. Degiovanni6, C. Miroglio1, E. Montacci1, A. Ardizzoni7, M. Lauriola8, D. Romaniello8 | 1Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy; 2Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy; Division of Medical Oncology, IRCCS; Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; 3Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy; Pathology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; 4Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy; Department of Otorhinolaryngology-Head and Neck Surgery, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; 5Microbiology Unit, IRCCS Azienda Ospedaliero-Universitaria of Bologna, Bologna, Italy; 6Pathology Unit, IRCCS Azienda Ospedaliero Universitaria di Bologna,Bologna, Italy; 7Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy; Division of Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; 8Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
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Syndecan expressions in the human amnion and chorionic plate
1753PDF: 636HTML: 653 -
MIAQuant, a novel system for automatic segmentation, measurement, and localization comparison of different biomarkers from serialized histological slices
2370PDF: 1157MIAQuant user Manual: 252MIAQuant source code: 310HTML: 71 -
A PRECLINICAL STUDY ON THE MODULATION OF THE MICROBIOTA–GUT–BRAIN AXIS BY A FUNCTIONAL SNACK PROMOTING HEALTHY AGING Bellitto V1, Grasselli F1, Martinelli I2, Nittari G2, Vittadini E1, Eleuteri AM1, Tayebati SK2, Bonfili L1 and Tomassoni D1 | 1School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy; 2School of Medicinal and Health Products Sciences, University of Camerino, Italy
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PARP-1 protein expression in glioblastoma multiforme
3109PDF: 1237HTML: 1794 -
P61 | IMMUNOPROFILE OF MERKEL CELLS IN THE HUMAN VAGINAL EPITHELIUM S. Polakovičová1, M. Borovský2, L. Maršík2, B. Filová3, I. Varga3, L. Sallicandro4 | 1Inst. of Hist. and Embr. MFCU in Bratislava, Bratislava, Slovakia; 21st Obst. and Gyn. Dep. FMCU with Repr. Med. Centre Hospital, Bratislava, Slovakia; 3Inst. of Hist. and Embr. MFCU in Bratislava, Bratislava, Slovakia; 4Dep. of Medicine and Surgery, University of Perugia, Perugia, Italy
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HUMAN INDUCED PLURIPOTENT STEM CELLS-DERIVED CEREBRAL ORGANOIDS AS A MODEL FOR C9ORF72-LINKED FRONTO-TEMPORAL DEMENTIA: INSIGHTS INTO NEURONAL AND GLIAL DIFFERENTIATION DYNAMICS Ferrero C1,2,3, Pacca P1,2, Vercelli A1,2 and Boido M1,2 | 1Department of Neuroscience “Rita Levi Montalcini”, University of Turin, Italy; 2Neuroscience Institute Cavalieri Ottolenghi, Italy 3University School for Advanced Studies IUSS Pavia, Pavia, Italy
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NADPH-d activity in rat thymus after the application of retinoid acid
1401PDF: 512HTML: 1281 -
P05 | ENTERIC NERVOUS SYSTEM NEUROPLASTICITY IN COLON OF ANIMAL MODELS OF OBESITY V. Bellitto1, I. Martinelli2, G. Nittari2, S.K. Tayebati2, D. Tomassoni1 | 1School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy; 2School of Medicinal and Health Products Sciences, University of Camerino, Camerino, Italy
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P72 | A SWAB NEGATIVE PATIENT AFTER SARS-COV-2 INFECTION DISPLAYS INCREASE OF VEGF AND FIBRONECTIN ASSOCIATED WITH ALTERATIONS OF INTERCELLULAR JUNCTIONS C. Simioni1, J.M. Sanz2, R. Gafà3, G. Cenacchi4, S. Occhionorelli3, R. Rizzo5, D. Bortolotti5, A. Passaro3, L.M. Neri3 | 1Department of Life Sciences and Biotechnology, University of Ferrara, Italy; 2Department of Chemical, Pharmaceutical and Agricultural, Sciences, University of Ferrara, Italy; 3Department of Translational Medicine, University of Ferrara, Italy; 4Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum University of Bologna, Italy; 5Department of Environmental and Prevention Sciences, University of Ferrara, Italy
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CALRETININ IMMUNOREACTIVITY IN NERVE CELLS OF THE HUMAN MIDBRAIN AND THEIR POTENTIAL ROLE IN NEURODEGENERATIVE DISORDERS Flace P1, Caporusso C2, Galletta D3, Stolfa M2, Cacciola A4,5, Scarcella VS2, Branca JJV6, Gulisano M6, Milardi D7, Gradini R8, Livrea P9 and Marzullo A2 | 1Medical School, University of Bari Aldo Moro, Bari, Italy; 2Department of Precision and Regenerative Medicine and Ionian Area, Pathology Unit, University of Bari Aldo Moro, Bari, Italy; 3Specialization School Neuropsychology, University of Campania Luigi Vanvitelli, Caserta, Italy; 4IRCCS Humanitas Research Hospital, Milan, Italy; 5Department of Biomedical Sciences, Humanotas University, Milan, Italy; 6Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; 7Brain Mapping Lab, Department of Biomedical, Dental Sciences and Morphological and Functional Imaging, University of Messina, Messina, Italy; 8Department of Experimental Medicine, Sapienza University, Roma, Italy; 9University of Bari Aldo Moro, Bari, Italy
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Ferritin expression in the periodontal tissues of primates
1287PDF: 687HTML: 17 -
P09 | EFFECTS OF NUTLIN-3A ACTIVITY ON 2D AND 3D RETINOBLASTOMA MODELS F. Bompan1, R. Foschi2, A. Dipinto3, F. Casciano2, G. Lodi4, A. Sanvido5, P. Severi4, L. Giari1, L. C. Cosenza5, R. Voltan2, A. Romani4 | 1Department of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy; 2Department of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy; LTTA Centre, University of Ferrara, Ferrara, Italy; 3Department of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy; 4Department of Translational Medicine, University of Ferrara, Ferrara, Italy; LTTA Centre, University of Ferrara, Ferrara, Italy; 5Department of Translational Medicine, University of Ferrara, Ferrara, Italy
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Decreased expression of Met during differentiation in rat lung
1601PDF: 742Supplementary: 294HTML: 272 -
P83 | INFLAMMATORY PROFILE IN SKIN, LUNG, AND KIDNEY OF A HOCL-INDUCED MURINE MODEL OF SYSTEMIC SCLEROSIS: AN IMMUNOHISTOCHEMICAL STUDY G. Vermiglio1, J. Freni1, F. Nicita1, A. Centofanti1, D. Labellarte1, E. Rizzuto1, A. Favaloro1, M. Runci Anastasi2, G.P. Anastasi1, G. Cutroneo1 | 1Department of Biomedical, Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy; 2Department of Maxillo-Facial Surgery, University of Rome, La Sapienza, Italy
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Lectins as versatile tools to explore cellular glycosylation
2440PDF: 1152HTML: 45 -
ENDOCRINE DISRUPTOR EXPOSURE ACROSS GESTATION AND LACTATION MODIFIES MATERNAL AND ANXIETY-RELATED BEHAVIORAL PATTERNS Ricci E1,2, Guarini E1, Marraudino M1,2 and Gotti S1,2 | 1Neuroscience Institute Cavalieri Ottolenghi (NICO), Regione Gonzole 10, Orbassano, Torino, Italy; 2Department of Neuroscience ‘Rita Levi Montalcini’, University of Torino, Torino, Italy
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A method for semi-automated image analysis of HLA class I tumour epithelium expression in rectal cancer
1553PDF: 723Supplementary: 205HTML: 15 -
P23 | CALRETININ IMMUNOREACTIVE NON-TRADITIONAL LARGE NEURONS IN THE GRANULAR LAYER OF THE HUMAN CEREBELLAR CORTEX P. Flace1, M. E. Caringella2, D. Galletta3, G. Santangelo3, C. Caporusso2, M. Stolfa2, A. Cacciola4, J.J.V. Branca5, G. Agazzino2, R. Gradini6, P. Livrea7, A. Marzullo2 | 1Medical School, University of Bari ‘Aldo Moro’, Bari, Italy; 2Section of Molecular Pathology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari ‘Aldo Moro’, Italy; 3Department of Psychology, Specialization School of Neuropsychology. University of Campania ‘Luigi Vanvitelli’, Caserta, Italy; 4Brain Mapping Lab, Department of Biomedical, Dental Sciences and Morphological and Functional Imaging, University of Messina, Messina, Italy; 5Department of Experimental and Clinical Medicine, University of Firenze, Firenze, Italy; 6Department of Experimental Medicine, Sapienza University, Roma, Italy; 7University of Bari ‘Aldo Moro’, Bari, Italy
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