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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

1.9
Impact Factor 2025
3.7
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1.9
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3.7
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  • miR-199a-5p inhibited HIF-1α to suppress the proliferation, migration, and differentiation of cardiac stem cells

    Sha Li, Cuigai Zhang, Yanping Liu, Cuiqiao Meng, Yang Xie, Shuren Li
    22-09-2025
    https://doi.org/10.4081/ejh.2025.4239
    643
    PDF: 577
    Supplementary: 83
    HTML: 25
  • pPKCα mediated-HIF-1α activation related to the morphological modifications occurring in neonatal myocardial tissue in response to severe and mild hyperoxia

    S. Zara, V. Macchi, R. De Caro, M. Rapino, A. Cataldi, A. Porzionato
    e2
    31-01-2012
    https://doi.org/10.4081/ejh.2012.e2
    1854
    PDF: 2515
    HTML: 2612
  • SerpinB3 administration protects liver against ischemia-reperfusion injury

    Cristian Turato, Mariapia Vairetti, Marta Cagna, Alessandra Biasiolo, Andrea Ferrigno, Santina Quarta, Mariagrazia Ruvoletto, Silvia De Siervi, Patrizia Pontisso, Laura Giuseppina Di Pasqua
    28-10-2022
    https://doi.org/10.4081/ejh.2022.3561
    1456
    PDF: 833
    HTML: 47
  • Peribiliary gland damage due to liver transplantation involves peribiliary vascular plexus and vascular endothelial growth factor

    Antonio Franchitto, Diletta Overi, Romina Mancinelli, Anna Paola Mitterhofer, Paolo Muiesan, Francesca Tinti, Ilaria Umbro, Stefan G. Hubscher, Paolo Onori, Eugenio Gaudio, Guido Carpino
    10-05-2019
    https://doi.org/10.4081/ejh.2019.3022
    2610
    PDF: 840
    Supplementary: 309
    HTML: 20
  • Upregulation of cardiac NO/NOS system during short-term hypoxia and the subsequent reoxygenation period

    A. Rus, M.L. Del Moral, F. Molina, M.A. Peinado
    e17
    17-05-2011
    https://doi.org/10.4081/ejh.2011.e17
    1341
    PDF: 581
    HTML: 1423
  • SRSF3 promotes the generation of XBP1s to stabilize autophagy and enhance hypoxia adaptation in glioma

    Bohu Liu, Xiaoran Zhang, Jintao Tian, Xiaobin Huang, Xuhui Li, Jinxi Zhao, Zhenghu Xu, Jun Pu
    03-03-2026
    https://doi.org/10.4081/ejh.2026.4530
    615
    PDF: 504
    HTML: 18
  • The role of miRNA-29b1 on the hypoxia-induced apoptosis in mammalian cardiomyocytes

    Bo Dai, Hailin Liu, Dingmin Juan, Kaize Wu, Ruhao Cao
    27-06-2024
    https://doi.org/10.4081/ejh.2024.4021
    1171
    PDF: 749
    HTML: 35
  • Decreased VEGFA alleviates the symptoms of LPS-induced sepsis in a mouse model by inhibiting glycolysis and thereby regulating the polarization of macrophages

    Jun Lin, Liping Jiang, Kun Guo, Ning Feng
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3528
    2179
    PDF: 1342
    Supplementary: 158
    HTML: 49
  • Oxygen tension-independent protection against hypoxic cell killing in rat liver by low sodium

    Andrea Ferrigno, Laura G. Di Pasqua, Clarissa Berardo, Veronica Siciliano, Plinio Richelmi, Mariapia Vairetti
    30-05-2017
    https://doi.org/10.4081/ejh.2017.2798
    2062
    PDF: 765
    HTML: 79
  • Degenerative effects in rat eyes after experimental ocular hypertension

    G. Scarsella, M. Nebbioso, S. Stefanini, N. Pescosolido
    e42
    08-10-2012
    https://doi.org/10.4081/ejh.2012.e42
    1625
    PDF: 642
    HTML: 209
  • VEGF promotes diabetic retinopathy by upregulating the PKC/ET/NF-κB/ICAM-1 signaling pathway

    Meiying Zhang, Min Zhou, Xia Cai, Yan Zhou, Xueling Jiang, Yan Luo, Yue Hu, Rong Qiu, Yanrong Wu, Yuejin Zhang, Yan Xiong
    27-10-2022
    https://doi.org/10.4081/ejh.2022.3522
    2785
    PDF: 1114
    HTML: 52
  • The substance P and neurokinin-1 receptor system in human thyroid cancer: an immunohistochemical study

    Inmaculada Isorna, Francisco Esteban, Juan Solanellas, Rafael Coveñas, Miguel Muñoz
    28-04-2020
    https://doi.org/10.4081/ejh.2020.3117
    1466
    PDF: 761
    HTML: 18
  • Expression of hyaluronan synthase 3 in deformed human temporomandibular joint discs: in vivo and in vitro studies

    T. Matsumoto, M. Inayama, I. Tojyo, N. Kiga, S. Fujita
    e50
    15-12-2010
    https://doi.org/10.4081/ejh.2010.e50
    1757
    PDF: 752
    HTML: 1421
  • Low ozone concentrations promote in vitro preservation of explanted articular cartilage: an ultrastructural study

    Giada Remoli, Chiara Rita Inguscio, Federico Boschi, Gabriele Tabaracci, Manuela Malatesta, Barbara Cisterna
    26-01-2026
    https://doi.org/10.4081/ejh.2026.4440
    1374
    PDF: 323
    HTML: 21
  • Substance P is overexpressed in cervical squamous cell carcinoma and promoted proliferation and invasion of cervical cancer cells in vitro

    Ying Wang, Shifa Yuan, Jing Ma, Hong Liu, Lizhen Huang, Fengzhen Zhang
    31-07-2023
    https://doi.org/10.4081/ejh.2023.3746
    1108
    PDF: 523
    HTML: 20
  • Dexmedetomidine attenuates neuroinflammation and microglia activation in LPS-stimulated BV2 microglia cells through targeting circ-Shank3/miR-140-3p/TLR4 axis

    Guangbao He, Yibo He, Hongwei Ni, Kai Wang, Yijun Zhu, Yang Bao
    26-07-2023
    https://doi.org/10.4081/ejh.2023.3766
    2344
    PDF: 1455
    HTML: 25
  • p53 and telomerase control rat myocardial tissue response to hypoxia and ageing

    A. Cataldi, S. Zara, M. Rapino, M. Zingariello, V. di Giacomo, A. Antonucci
    e25
    09-12-2009
    https://doi.org/10.4081/ejh.2009.e25
    1503
    PDF: 827
  • Image by <a href="https://pixabay.com/users/spotsoflight-6345617/?utm_source=link-attribution&amp;utm_medium=referral&amp;utm_campaign=image&amp;utm_content=2744729">Monika Robak</a> from <a href="https://pixabay.com//?utm_source=link-attribution&amp;utm_medium=referral&amp;utm_campaign=image&amp;utm_content=2744729">Pixabay</a>

    The contribution of immunohistochemistry to the development of hydrogels for skin repair and regeneration

    Flavia Carton
    23-02-2023
    https://doi.org/10.4081/ejh.2023.3679
    2112
    PDF: 1080
    HTML: 54
  • Colchicine alleviates severe acute pancreatitis in rats by inhibiting acinar cell ferroptosis via LCN2/MAPK/ERK signaling axis

    Liu Yang, Xiaoyi Zheng, Yang Zhang, Yue Li, Lei Li, Feng Liu
    11-05-2026
    https://doi.org/10.4081/ejh.2026.4557
    522
    PDF: 952
    Supplementary: 55
    HTML: 22
  • Ozone and procaine increase secretion of platelet-derived factors in platelet-rich plasma

    Chiara Rita Inguscio, Barbara Cisterna, Maria Assunta Lacavalla, Franco Donati, Osvaldo Angelini, Gabriele Tabaracci, Manuela Malatesta
    10-10-2023
    https://doi.org/10.4081/ejh.2023.3879
    4868
    PDF: 936
    HTML: 33
  • Effects of the lncRNA ENST00000623984 on colon cancer and the biological characteristics of colon cancer cells

    Zhi-bao Liu, Jing-hua Zhang, Jing-hua Gao, Jian Shi
    12-07-2021
    https://doi.org/10.4081/ejh.2021.3215
    2331
    PDF: 622
    HTML: 35
  • P14 | THE ROLE OF CHROMATIN REORGANIZATION IN HYPOXIA ADAPTATION M. Cavallo1, C. Casali1, L. Giulini1, A. Dia1, D. Tunesi1, G. Milanesi1, G. Mazzini2, M. Biggiogera1 | 1Department of Biology and Biotechnology “L. Spallanzani”, University of Pavia, Pavia; Italy; 2Institute of Molecular Genetics, National Research Council (IGMCNR), Pavia, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4334
    230
  • On the future contents of a small journal of histochemistry

    C. Pellicciari
    e51
    10-12-2012
    https://doi.org/10.4081/ejh.2012.e51
    2676
    PDF: 1022
    HTML: 949
  • Overexpression of hsa_circ_0006470 inhibits the malignant behavior of gastric cancer cells via regulation of miR-1234/TP53I11 axis

    Jinbi Xie, Yong Ning, Lihang Zhang, Yuan Lin, Runsheng Guo, Shanjuan Wang
    03-10-2022
    https://doi.org/10.4081/ejh.2022.3477
    2176
    PDF: 744
    HTML: 48
  • Elevated caspase 3 expression correlates with severe inflammation in Crohn’s disease

    Nafie Sejdiu, Michael Naumann, Michael Vieth
    03-06-2026
    https://doi.org/10.4081/ejh.2026.4570
    396
    PDF: 246
    HTML: 16
  • Histochemical and morphological aspects of fresh frozen bone: a preliminary study

    F.S. De Ponte, G. Cutroneo, R. Falzea, G. Rizzo, L. Catalfamo, A. Favaloro, G. Vermiglio, M. Runci, A. Centofanti, G. Anastasi
    06-12-2016
    https://doi.org/10.4081/ejh.2016.2642
    1639
    PDF: 688
    HTML: 170
  • Crocin exerts anti-tumor effect in colon cancer cells via repressing the JAK pathway

    Hui Yang, Yunlong Zhang, Desheng Zhang, Liping Qian, Tianxing Yang, Xiaocheng Wu
    12-09-2023
    https://doi.org/10.4081/ejh.2023.3697
    1461
    PDF: 740
    HTML: 26
  • Seasonal expressions of VEGF and its receptors VEGFR1 and VEGFR2 in the prostate of the wild ground squirrels (Spermophilus dauricus)

    Yuchen Yao, Wenqian Xie, Di Chen, Yingying Han, Zhengrong Yuan, Haolin Zhang, Qiang Weng
    24-03-2021
    https://doi.org/10.4081/ejh.2021.3219
    1624
    PDF: 647
    HTML: 54
  • Forever particles: histochemistry in the plasticene age

    Beatrice Camia, Andrea Casasco, Manuela Monti
    01-08-2025
    https://doi.org/10.4081/ejh.2025.4226
    1581
    PDF: 701
    HTML: 69
  • Impact of Histochemistry on biomedical research: looking through the articles published in a long-established histochemical journal

    C. Pellicciari
    30-12-2014
    https://doi.org/10.4081/ejh.2014.2474
    2512
    PDF: 730
    HTML: 827
  • Pretreatment with geniposide mitigates myocardial ischemia/reperfusion injury by modulating inflammatory response through TLR4/NF-κB pathway

    Yanmei Yao, Leqing Lin, Wenxue Tang, Yueliang Shen, Fayu Chen, Ning Li, Baiyong Wang
    08-09-2023
    https://doi.org/10.4081/ejh.2023.3742
    1351
    PDF: 535
    HTML: 29
  • PDTC ameliorates neuropathic pain by inhibiting microglial activation via blockage of the TNFα-CX3CR1 pathway

    Xilei Li, Zhi Ye, Qulian Guo, E Wang, Yundan Pan
    12-03-2021
    https://doi.org/10.4081/ejh.2021.3184
    2342
    PDF: 983
    HTML: 25
  • Knockdown of miR-411-3p induces M2 macrophage polarization and promotes colorectal cancer progression by regulation of MMP7

    Tianliang Bai, Ping Li, Yabin Liu, Bindan Cai, Gang Li, Wenbin Wang, Rui Yan, Xiangkui Zheng, Shangkun Du
    05-05-2025
    https://doi.org/10.4081/ejh.2025.4178
    1196
    PDF: 484
    Supplementary: 75
    HTML: 66
  • Knockdown of VEGFR2 inhibits proliferation and induces apoptosis in hemangioma-derived endothelial cells

    J.M. Ou, Z.Y. Yu, M.K. Qiu, Y.X. Dai, Q. Dong, J. Shen, X.F. Wang, Y.B. Liu, Z.W. Quan, Z.W. Fei
    17-03-2014
    https://doi.org/10.4081/ejh.2014.2263
    3850
    PDF: 1104
    HTML: 609
  • Downregulation of S100 calcium-binding A4 (S100A4) ameliorates hepatic fibrosis via regulating Wnt/β-catenin signaling pathway

    Chixian Zhang, Kai Bai, Dexu Li
    14-04-2025
    https://doi.org/10.4081/ejh.2025.4186
    1560
    PDF: 561
    HTML: 42
  • Inhibition of HMGB1 suppresses inflammation and catabolism in temporomandibular joint osteoarthritis via NF-κB signaling pathway

    Yan Yan Li, Ya Ping Feng, Li Liu, Jin Ke, Xing Long
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3357
    2376
    PDF: 1209
    HTML: 46
  • Histochemistry as an irreplaceable approach for investigating functional cytology and histology

    C. Pellicciari
    e41
    19-12-2013
    https://doi.org/10.4081/ejh.2013.e41
    3475
    PDF: 968
    HTML: 414
  • Clinicopathological assessment of cancer/testis antigens NY‑ESO‑1 and MAGE‑A4 in osteosarcoma

    Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Naohiro Oka, Ryosuke Kakinoki, Masao Akagi
    23-06-2022
    https://doi.org/10.4081/ejh.2022.3377
    1898
    PDF: 1056
    HTML: 33
  • Immunohistochemical analysis of YB-1 expression in the developing mouse eye

    Alexander Forian Nass, Hella Wolf, Saadettin Sel , Thomas Kalinski, Norbert Nass
    03-11-2025
    https://doi.org/10.4081/ejh.2025.4244
    1876
    PDF: 303
    HTML: 37
  • Immunoreactivity for thymosin beta 4 and thymosin beta 10 in the adult rat oro-gastro-intestinal tract

    S. Nemolato, J. Ekstrom, T. Cabras, C. Gerosa, D. Fanni, E. Di Felice, A. Locci, I. Messana, M. Castagnola, G. Faa
    e17
    07-05-2013
    https://doi.org/10.4081/ejh.2013.e17
    2584
    PDF: 841
    HTML: 542
  • Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model

    Juan Fan, Yu Ma, Liying Sun, Suhua Miao, Jianghong He
    20-04-2026
    https://doi.org/10.4081/ejh.2026.4533
    752
    PDF: 355
    HTML: 30
  • DNMT1 regulates IL-6- and TGF-β1-induced epithelial mesenchymal transition in prostate epithelial cells

    Hui Xu, Yanbo Chen, Qi Chen, Huan Xu, Yanxia Wang, Jiao Yu, Juan Zhou, Zhong Wang, Bing Xu
    03-05-2017
    https://doi.org/10.4081/ejh.2017.2775
    2797
    PDF: 1104
    HTML: 195
  • Mast cells in meningiomas

    Antonio D'Amati, Roberto Tamma, Tiziana Annese, Anna Rizzi, Domenico Ribatti
    18-04-2024
    https://doi.org/10.4081/ejh.2024.3973
    1606
    PDF: 521
    HTML: 31
  • Postnatal development of thalamic reticular nucleus projections to the anterior thalamic nuclei in rats

    Hitoshi Fujita, Kosuke Imura, Masahito Takiguchi, Kengo Funakoshi
    24-03-2022
    https://doi.org/10.4081/ejh.2022.3370
    1868
    PDF: 1137
    HTML: 41
  • P11 | DOMINO TRANSPLANTATION IN MNGIE: IS THE LIVER A SUITABLE GRAFT? E. Boschetti1, I. Neri1, S. Blando1, C. Malagelada2, L. Caporali3, R. D’Angelo4, R. Rinaldi4, S. Mongiorgi1, V. Carelli3, R. De Giorgio5, L. Manzoli1, S. Ratti1 | 1Center of Clinical Surgical Molecular and Experimental Anatomy Alma Mater Studiorum – University of Bologna, Italy; 2Digestive System Research Unit, University Hospital Vall d’Hebron; Barcelona, Spain; 3IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy; 4IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; 5Department of Translational Medicine, University of Ferrara, Ferrara, Italy

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4331
    269
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
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Huina Su et al.
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Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

is an Open Access, peer-reviewed journal published by PAGEPress®, Pavia, Italy. All credits and honors to PKP for their OJS.

pISSN: 1121-760X
eISSN: 2038-8306

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