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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

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1.9
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  • Characterizing the activation of the Wnt signaling pathway in hilar cholangiocarcinoma using a tissue microarray approach

    W. Chen, J. Liang, L. Huang, J. Cai, Y. Lei, J. Lai, L. Liang, K. Zhang
    09-02-2016
    https://doi.org/10.4081/ejh.2016.2536
    1945
    PDF: 898
    HTML: 348
  • Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

    Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou
    06-08-2025
    https://doi.org/10.4081/ejh.2025.4228
    1446
    PDF: 745
    HTML: 25
  • Astragaloside IV inhibits nasopharyngeal carcinoma progression by inhibiting SATB2/Wnt/PD-L1 pathway and enhancing the killing activity of T cells

    Yinping Zeng, Jiajun Huang, Tingting Duan, Xiaofeng Wang
    28-05-2026
    https://doi.org/10.4081/ejh.2026.4540
    372
    PDF: 278
    HTML: 14
  • Downregulation of S100 calcium-binding A4 (S100A4) ameliorates hepatic fibrosis via regulating Wnt/β-catenin signaling pathway

    Chixian Zhang, Kai Bai, Dexu Li
    14-04-2025
    https://doi.org/10.4081/ejh.2025.4186
    1437
    PDF: 528
    HTML: 35
  • Expression of bone morphogenetic protein signaling pathway players in the jejunum and colon of adult rats

    Emma Cogo, Edwin Fouché, Charline Buisson, Adenike Omotoyinbo, Fabrice Pierre, Françoise Guéraud, Pascale Plaisancié
    21-08-2025
    https://doi.org/10.4081/ejh.2025.4174
    700
    PDF: 491
    HTML: 27
  • Knockdown of ARHGAP30 inhibits ovarian cancer cell proliferation, migration, and invasiveness by suppressing the PI3K/AKT/mTOR signaling pathway

    Xiaoyan Chu, Jun Lou, Yun Yi, Linlin Zhong, Ouping Huang
    11-05-2023
    https://doi.org/10.4081/ejh.2023.3653
    1405
    PDF: 722
    HTML: 44
  • Role of β-catenin expression in paediatric mesenchymal lesions: a tissue microarray-based immunohistochemical study

    A. Santoro, G. Pannone, M.E. Errico, D. Bifano, G. Lastilla, P. Bufo, C. Loreto, V. Donofrio
    e25
    02-07-2012
    https://doi.org/10.4081/ejh.2012.e25
    1614
    PDF: 692
    HTML: 5494
  • VEGF promotes diabetic retinopathy by upregulating the PKC/ET/NF-κB/ICAM-1 signaling pathway

    Meiying Zhang, Min Zhou, Xia Cai, Yan Zhou, Xueling Jiang, Yan Luo, Yue Hu, Rong Qiu, Yanrong Wu, Yuejin Zhang, Yan Xiong
    27-10-2022
    https://doi.org/10.4081/ejh.2022.3522
    2584
    PDF: 1088
    HTML: 49
  • Swertiamarin suppresses proliferation, migration, and invasion of hepatocellular carcinoma cells via negative regulation of FRAT1

    Shufeng Xiao, Haoren Tang, Yao Bai, Renchao Zou, Zongfang Ren, Xuesong Wu, Zhitian Shi, Song Lan, Wei Liu, Tiangen Wu, Cheng Zhang, Lin Wang
    19-10-2020
    https://doi.org/10.4081/ejh.2020.3169
    1600
    PDF: 792
    HTML: 36
  • LncRNA FBXO18-AS promotes gastric cancer progression by TGF-β1/Smad signaling

    Yiming Zhang, Wanqiong Zheng, Liang Zhang, Yechun Gu, Lihe Zhu, Yingpeng Huang
    20-06-2023
    https://doi.org/10.4081/ejh.2023.3667
    1315
    PDF: 787
    Supplementary: 111
    HTML: 30
  • Immunohistochemical detection of putative pathogenetic factors in adhesions of infants: a pilot study

    Arvis Pauliņš, Anna Junga, Māra Pilmane
    10-02-2026
    https://doi.org/10.4081/ejh.2026.4438
    330
    PDF: 462
    HTML: 12
  • microRNA-16-5p suppresses cell proliferation and angiogenesis in colorectal cancer by negatively regulating forkhead box K1 to block the PI3K/Akt/mTOR pathway

    Xin Huang, Xuan Xu, Huajing Ke, Xiaolin Pan, Jiaoyu Ai, Ruyi Xie, Guilian Lan, Yang Hu, Yao Wu
    10-05-2022
    https://doi.org/10.4081/ejh.2022.3333
    2135
    PDF: 957
    HTML: 34
  • Therapeutic effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles on ovarian functions through the PI3K/Akt cascade in mice with premature ovarian failure

    Nan Li, Xue Fan, Lihong Liu, Yanbing Liu
    27-07-2023
    https://doi.org/10.4081/ejh.2023.3506
    1903
    PDF: 1159
    HTML: 27
  • Extracellular vesicles from bone mesenchymal stem cells transport microRNA-206 into osteosarcoma cells and target NRSN2 to block the ERK1/2-Bcl-xL signaling pathway

    Alimu Keremu, Pazila Aila, Aikebaier Tusun , Maimaitiaili Abulikemu, Xiaoguang Zou
    22-06-2022
    https://doi.org/10.4081/ejh.2022.3394
    2126
    PDF: 1390
    HTML: 32
  • New bitongling (NBTL) ameliorates rheumatoid arthritis in rats through inhibiting JAK2/STAT3 signaling pathway

    Xiang Li, Yu Xie, An Kang, Yue Wang
    17-02-2021
    https://doi.org/10.4081/ejh.2021.3202
    2587
    PDF: 1035
    HTML: 30
  • β-catenin mediates the effect of GLP-1 receptor agonist on ameliorating hepatic steatosis induced by high fructose diet

    Zhe Gao, Guang-Yao Song, Lu-Ping Ren, Hui-Juan Ma, Bo-Qing Ma, Shu-Chun Chen
    15-09-2020
    https://doi.org/10.4081/ejh.2020.3160
    1792
    PDF: 905
    HTML: 22
  • NOP14 regulates the growth, migration, and invasion of colorectal cancer cells by modulating the NRIP1/GSK-3β/β-catenin signaling pathway

    Xuanjin Zhu, Weilu Jia, Yong Yan, Yong Huang, Bailin Wang
    02-07-2021
    https://doi.org/10.4081/ejh.2021.3246
    3065
    PDF: 817
    HTML: 42
  • DPY30 promotes the growth and survival of osteosarcoma cell by regulating the PI3K/AKT signal pathway

    Gong Cheng, Fengmin An, Zhilin Cao, Mingdi Zheng, Zhongyuan Zhao, Hao Wu
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3413
    1379
    PDF: 690
    Supplementary: 119
    HTML: 38
  • Expressions of ZNF436, β-catenin, EGFR, and CMTM5 in breast cancer and their clinical significances

    Zhi Chen, Na Cui, Ji-sen Zhao, Jian-fei Wu, Fang Ma, Cong Li, Xian-yi Liu
    20-01-2021
    https://doi.org/10.4081/ejh.2021.3173
    2418
    PDF: 865
    Supplementary: 206
    HTML: 22
  • Quercetin reverses 5-fluorouracil resistance in colon cancer cells by modulating the NRF2/HO-1 pathway

    Zhongzhu Tang, Lei Wang, Yunwang Chen, Xiaomin Zheng, Runyu Wang, Bingxue Liu, Shiqi Zhang, Huimin Wang
    07-08-2023
    https://doi.org/10.4081/ejh.2023.3719
    2276
    PDF: 1083
    HTML: 30
  • miR-19a targeting CLCA4 to regulate the proliferation, migration, and invasion of colorectal cancer cells

    Huiwen Li, Bo Huang
    10-03-2022
    https://doi.org/10.4081/ejh.2022.3381
    2195
    PDF: 778
    HTML: 32
  • Downregulation of Williams syndrome transcription factor (WSTF) suppresses glioblastoma cell growth and invasion by inhibiting PI3K/AKT signal pathway

    Liyuan Yang, Chunfu Du, Hui Chen, Zhengwen Diao
    17-11-2021
    https://doi.org/10.4081/ejh.2021.3255
    1297
    PDF: 681
    HTML: 51
  • Aberrant DKK3 expression in the oral leukoplakia and oral submucous fibrosis: a comparative immunohistochemical study

    T. Al-dhohorah, M. Mashrah, Z. Yao, J. Huang
    16-06-2016
    https://doi.org/10.4081/ejh.2016.2629
    2815
    PDF: 889
    HTML: 351
  • Crocin exerts anti-tumor effect in colon cancer cells via repressing the JAK pathway

    Hui Yang, Yunlong Zhang, Desheng Zhang, Liping Qian, Tianxing Yang, Xiaocheng Wu
    12-09-2023
    https://doi.org/10.4081/ejh.2023.3697
    1423
    PDF: 714
    HTML: 24
  • Effect of CDX2 on proliferation, invasion, migration, and apoptosis of duodenal cancer cells

    Jun Pan, Yi Zhao, Yu Zhang, Yuhe Zhou, Fengxuan Zhang, Yitian Chen, Xiaoyuan Chu
    24-04-2025
    https://doi.org/10.4081/ejh.2025.4203
    847
    PDF: 378
    HTML: 59
  • Forever particles: histochemistry in the plasticene age

    Beatrice Camia, Andrea Casasco, Manuela Monti
    01-08-2025
    https://doi.org/10.4081/ejh.2025.4226
    1513
    PDF: 649
    HTML: 62
  • Identification of abnormally high expression of POGZ as a new biomarker associated with a poor prognosis in osteosarcoma

    Sikuan Zheng, Yue Liu, Haohe Sun, Jingyu Jia, Tianlong Wu, Rui Ding, Xigao Cheng
    03-09-2021
    https://doi.org/10.4081/ejh.2021.3264
    2069
    PDF: 775
    Supplementary: 159
    HTML: 33
  • MiR-130a-5p contributed to the progression of endothelial cell injury by regulating FAS

    Wei Wang, Wenbo Tang, Erbo Shan, Lei Zhang, Shiyuan Chen, Chaowen Yu, Yong Gao
    31-05-2022
    https://doi.org/10.4081/ejh.2022.3342
    1268
    PDF: 855
    HTML: 32
  • Tumor cell-derived exosomal lncRNA LOC441178 inhibits the tumorigenesis of esophageal carcinoma through suppressing macrophage M2 polarization

    Jiangmu Chen, Zongchi Chen, Weitao Hu, Daxing Cai
    14-10-2022
    https://doi.org/10.4081/ejh.2022.3510
    1395
    PDF: 723
    HTML: 42
  • Bovine pericardium membrane, gingival stem cells, and ascorbic acid: a novel team in regenerative medicine

    Jacopo Pizzicannella, Guya D. Marconi, Sante D. Pierdomenico, Marcos F.X.B. Cavalcanti, Francesca Diomede, Oriana Trubiani
    25-09-2019
    https://doi.org/10.4081/ejh.2019.3064
    1784
    PDF: 882
    HTML: 27
  • Developmental expression of high-mobility group box 1 (HMGB1) in the mouse cochlea

    Wenjing Liu, Shanshan Ming, Xiaobing Zhao, Xin Zhu, Yuxiang Gong
    01-09-2023
    https://doi.org/10.4081/ejh.2023.3704
    1276
    PDF: 1052
    HTML: 28
  • High glucose inhibits neural differentiation by excessive autophagy via peroxisome proliferator-activated receptor gamma

    Yin Pan, Di Qiu, Shu Chen, Xiaoxue Han, Ruiman Li
    11-05-2023
    https://doi.org/10.4081/ejh.2023.3691
    1381
    PDF: 946
    HTML: 26
  • miR-199a-5p inhibited HIF-1α to suppress the proliferation, migration, and differentiation of cardiac stem cells

    Sha Li, Cuigai Zhang, Yanping Liu, Cuiqiao Meng, Yang Xie, Shuren Li
    22-09-2025
    https://doi.org/10.4081/ejh.2025.4239
    580
    PDF: 437
    Supplementary: 72
    HTML: 24
  • SRSF3 promotes the generation of XBP1s to stabilize autophagy and enhance hypoxia adaptation in glioma

    Bohu Liu, Xiaoran Zhang, Jintao Tian, Xiaobin Huang, Xuhui Li, Jinxi Zhao, Zhenghu Xu, Jun Pu
    03-03-2026
    https://doi.org/10.4081/ejh.2026.4530
    579
    PDF: 476
    HTML: 13
  • WT1 expression in the human fetus during development

    R. Ambu, L. Vinci, C. Gerosa, D. Fanni, E. Obinu, A. Faa, V. Fanos
    29-06-2015
    https://doi.org/10.4081/ejh.2015.2499
    2349
    PDF: 924
    HTML: 987
  • IncRNA MAPKAPK5-AS1 promotes proliferation and migration of thyroid cancer cell lines by targeting miR-519e-5p/YWHAH

    Yan Zhou, Shanshan Liu, Yan Luo, Meiying Zhang, Xueling Jiang, Yan Xiong
    03-12-2020
    https://doi.org/10.4081/ejh.2020.3177
    2336
    PDF: 925
    HTML: 17
  • Tumor cells-derived exosomal PD-L1 promotes the growth and invasion of lung cancer cells in vitro via mediating macrophages M2 polarization

    Xiangjun Lu, Jian Shen, Siyuan Huang, Dongdong Liu, Haitao Wang
    01-08-2023
    https://doi.org/10.4081/ejh.2023.3784
    2196
    PDF: 953
    HTML: 27
  • Nuclear damages and oxidative stress: new perspectives for laminopathies

    G. Lattanzi, S. Marmiroli, A. Facchini, N.M. Maraldi
    e45
    18-10-2012
    https://doi.org/10.4081/ejh.2012.e45
    2142
    PDF: 983
    HTML: 210
  • circRNA-79530 regulates Twist-mediated mitochondrial damage via sponging miR-214 affecting hypoxia/reoxygenation-induced injury in H9c2 cardiomyocytes

    Ziyang Yu, Wenbo Xu, Yirong Teng, Tingting Li, Ren Guo, Ju Li, Xichen Li, Yanping Li, Yinglu Hao
    22-08-2025
    https://doi.org/10.4081/ejh.2025.4230
    437
    PDF: 358
    HTML: 12
  • Independent and interactive roles of hirudin and HMGB1 interference in protecting renal function by regulating autophagy, apoptosis, and kidney injury in chronic kidney disease

    Ying Li, Xuan Gao, Yao Chen, Huihui Li, Jing Tang, Wei Sun
    07-04-2025
    https://doi.org/10.4081/ejh.2025.4182
    1272
    PDF: 759
    HTML: 50
  • The role of miR-143-3p/FNDC1 axis on the progression of non-small cell lung cancer

    Zhanshu Ma, Qi Gao, Wenjing Xin, Lei Wang, Yan Chen, Chang Su, Songyan Gao, Ruiling Sun
    03-05-2023
    https://doi.org/10.4081/ejh.2023.3577
    2138
    PDF: 644
    HTML: 40
  • Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells

    Huina Su, Ruiqiong Ma, Dehui Su, Cheng Tan, Ye Zhu, Xin Yang
    21-04-2026
    https://doi.org/10.4081/ejh.2026.4537
    967
    PDF: 604
    HTML: 22
  • alpha2,3 sialic acid processing enzymes expression in gastric cancer tissues reveals that ST3Gal3 but not Neu3 are associated with Lauren's classification, angiolymphatic invasion and histological grade

    Michael W.L. Quirino, Amanda P.B. Albuquerque, Maria F.D. de Souza, Antônio F. da Silva Filho, Mário R. Martins, Maira G. da Rocha Pitta, Michelly C. Pereira, Moacyr J.B. de Melo Rêgo
    29-09-2022
    https://doi.org/10.4081/ejh.2022.3330
    1589
    PDF: 872
    Supplementary: 143
    HTML: 36
  • miR-29a-3p enhances the radiosensitivity of oral squamous cell carcinoma cells by inhibiting ADAM12

    Cuihong Jiang, Feng Liu , Shuai Xiao, Lili He, Wenqiong Wu, Qi Zhao
    27-09-2021
    https://doi.org/10.4081/ejh.2021.3295
    1475
    PDF: 1082
    HTML: 32
  • High WTAP expression level as a promising biomarker for poor prognosis in colorectal cancer: a pilot study

    Michela Relucenti, Claudia Tito, Paolo Mercantini, Emanuela Pilozzi, Claudio Barbaranelli, Loredana Cristiano, Daniela Savarese, Daniela Bastianelli, Francesco Fazi, Vincenzo Petrozza, Xiaobo Li, Rui Chen, Selenia Miglietta, Giuseppe Familiari
    16-12-2024
    https://doi.org/10.4081/ejh.2024.4145
    1495
    PDF: 621
    HTML: 12
  • Sodium hyaluronate promotes proliferation, autophagy, and migration of corneal epithelial cells by downregulating miR-18a in the course of corneal epithelial injury

    Yingzhuo Guo, Hua Wang
    15-06-2023
    https://doi.org/10.4081/ejh.2023.3663
    1609
    PDF: 688
    Supplementary: 138
    HTML: 31
  • Reelin expression in human liver of patients with chronic hepatitis C infection

    Simone Carotti, Giuseppe Perrone, Michelina Amato, Umberto Vespasiani Gentilucci, Daniela Righi, Maria Francesconi, Claudio Pellegrini, Francesca Zalfa, Maria Zingariello, Antonio Picardi, Andrea Onetti Muda, Sergio Morini
    17-03-2017
    https://doi.org/10.4081/ejh.2017.2745
    3379
    PDF: 1035
    HTML: 370
  • Peribiliary gland damage due to liver transplantation involves peribiliary vascular plexus and vascular endothelial growth factor

    Antonio Franchitto, Diletta Overi, Romina Mancinelli, Anna Paola Mitterhofer, Paolo Muiesan, Francesca Tinti, Ilaria Umbro, Stefan G. Hubscher, Paolo Onori, Eugenio Gaudio, Guido Carpino
    10-05-2019
    https://doi.org/10.4081/ejh.2019.3022
    2550
    PDF: 819
    Supplementary: 300
    HTML: 19
  • Is there still room for novelty, in histochemical papers?

    Carlo Pellicciari
    16-12-2016
    https://doi.org/10.4081/ejh.2016.2758
    2978
    PDF: 744
    HTML: 284
  • Overexpression of hsa_circ_0001861 inhibits pulmonary fibrosis through targeting miR-296-5p/BCL-2 binding component 3 axis

    Tao Wu, Shikui Wu, Hailu Jiao, Jun Feng, Xiang Zeng
    02-10-2023
    https://doi.org/10.4081/ejh.2023.3839
    1567
    PDF: 865
    HTML: 43
  • Developmental immunolocalization of the Klotho protein in mouse kidney epithelial cells

    J.H. Song, M.Y. Lee, Y.J. Kim, S.R. Park, J. Kim, S.Y. Ryu, J.Y. Jung
    24-01-2014
    https://doi.org/10.4081/ejh.2014.2256
    3833
    PDF: 974
    HTML: 513
  • Apoptosis pattern and alterations of expression of apoptosis-related factors of supporting cells in Kölliker’s organ in vivo in early stage after birth in rats

    Jun Liu, Linbin Cai, Yuanyuan He, Jun Yang
    07-08-2017
    https://doi.org/10.4081/ejh.2017.2706
    2508
    PDF: 845
    HTML: 218
  • miR-627-5p inhibits malignant progression of cervical cancer by targeting ANGPTL4

    Xinghua Wu, Kai Lin, Chen Gao, Yinfang Ni, Li Zhang, Tailai Yang, Jinguo Chen
    07-04-2025
    https://doi.org/10.4081/ejh.2025.4161
    1622
    PDF: 518
    HTML: 34
  • Concomitant use of heat-shock protein 70, glutamine synthetase and glypican-3 is useful in diagnosis of HBV-related hepatocellular carcinoma with higher specificity and sensitivity

    Bita Moudi, Zahra Heidari, Hamidreza Mahmoudzadeh-Sagheb, Seyed-Moayed Alavian, Kamran B. Lankarani, Parisa Farrokh, Jens Randel Nyengaard
    29-01-2018
    https://doi.org/10.4081/ejh.2018.2859
    2397
    PDF: 1111
    HTML: 84
  • Clinicopathological assessment of PD-1/PD-L1 immune checkpoint expression in desmoid tumors

    Kazuhiko Hashimoto, Shunji Nishimura, Yu Shinyashiki, Tomohiko Ito, Ryosuke Kakinoki, Masao Akagi
    26-04-2023
    https://doi.org/10.4081/ejh.2023.3688
    994
    PDF: 697
    HTML: 25
  • Histochemistry as a versatile research toolkit in biological research, not only an applied discipline in pathology

    Carlo Pellicciari
    21-12-2018
    https://doi.org/10.4081/ejh.2018.3006
    2211
    PDF: 834
    HTML: 31
  • GalNAc-T15 in gastric adenocarcinoma: Characterization according to tissue architecture and cellular location

    Mário S. de Souza Albuquerque, Antônio F. da Silva-filho, Marina Ferraz Cordeiro, Maria de Fátima Deodato de Souza, Michael W.L. Quirino, Luiza R. Amorim Lima, Maira G. da Rocha Pitta, Mario R. Martins, Moacyr J.B. de Melo Rêgo
    14-06-2018
    https://doi.org/10.4081/ejh.2018.2931
    3591
    PDF: 630
    Supplementary: 244
    HTML: 34
  • Morphological and immunohistochemical study of ovarian and tubal dysplasia associated with tamoxifen

    G. Chene, N. Radosevic-Robin, A.S. Tardieu, A. Cayre, I. Raoelfils, P. Dechelotte, J. Dauplat, F. Penault Llorca
    15-04-2014
    https://doi.org/10.4081/ejh.2014.2251
    2446
    PDF: 915
    HTML: 478
1 - 58 of 58 items

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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
Nana Bao et al.
20 April 2026
Vol. 70 No. 2 (2026)
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells
Huina Su et al.
21 April 2026
Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

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