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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

1.9
Impact Factor 2025
3.7
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1.9
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3.7
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  • The Qi-Bang-Yi-Shen formula ameliorates renal dysfunction and fibrosis in rats with diabetic kidney disease via regulating PI3K/AKT, ERK and PPARγ signaling pathways

    Zhi Wang, Guihua Jian, Teng Chen, Yiping Chen, Junhui Li, Niansong Wang
    01-03-2023
    https://doi.org/10.4081/ejh.2023.3648
    5047
    PDF: 1180
    HTML: 47
  • Molecular characterization of nephron progenitors and their early epithelial derivative structures in the nephrogenic zone of the canine fetal kidney

    Rawah Faraj, Angela Irizarry-Alfonzo, Pawan Puri
    23-09-2019
    https://doi.org/10.4081/ejh.2019.3049
    1641
    PDF: 879
    HTML: 63
  • Independent and interactive roles of hirudin and HMGB1 interference in protecting renal function by regulating autophagy, apoptosis, and kidney injury in chronic kidney disease

    Ying Li, Xuan Gao, Yao Chen, Huihui Li, Jing Tang, Wei Sun
    07-04-2025
    https://doi.org/10.4081/ejh.2025.4182
    1277
    PDF: 766
    HTML: 51
  • Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

    Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou
    06-08-2025
    https://doi.org/10.4081/ejh.2025.4228
    1456
    PDF: 751
    HTML: 25
  • Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function

    Zhijiang Chen, Huili Wang, Bin Hu, Xinxin Chen, Meiyu Zheng, Lili Liang, Juanjuan Lyu, Qiyi Zeng
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3412
    2633
    PDF: 1490
    HTML: 36
  • Developmental immunolocalization of the Klotho protein in mouse kidney epithelial cells

    J.H. Song, M.Y. Lee, Y.J. Kim, S.R. Park, J. Kim, S.Y. Ryu, J.Y. Jung
    24-01-2014
    https://doi.org/10.4081/ejh.2014.2256
    3835
    PDF: 976
    HTML: 513
  • Combination of tolvaptan and valsartan improves cardiac and renal functions in doxorubicin-induced heart failure in mice

    Fengqin Yan, Hong Zhu, Yingxia He, Qinqin Wu, Xiaoyu Duan
    11-11-2022
    https://doi.org/10.4081/ejh.2022.3563
    1880
    PDF: 928
    Supplementary: 153
    HTML: 38
  • Emodin improves renal fibrosis in chronic kidney disease by regulating mitochondrial homeostasis through the mediation of peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC-1α)

    Liuchang Feng, Zaoqiang Lin, Zeyong Tang, Lin Zhu, Shu Xu, Xi Tan, Xinyuan Wang, Jianling Mai, Qinxiang Tan
    13-05-2024
    https://doi.org/10.4081/ejh.2024.3917
    2148
    PDF: 909
    HTML: 54
  • Receptor-mediated endocytosis of lysozyme in renal proximal tubules of the frog Rana temporaria

    E.V. Seliverstova, N.P. Prutskova
    13-04-2015
    https://doi.org/10.4081/ejh.2015.2482
    2576
    PDF: 863
    HTML: 1138
  • Endoplasmic reticulum stress contributed to inflammatory bowel disease by activating p38 MAPK pathway

    Yan Long, Yan Zhao, Xiaoqing Ma, Ya Zeng, Tian Hu, Weijie Wu, Chongtian Deng, Jinyue Hu, Yueming Shen
    23-05-2022
    https://doi.org/10.4081/ejh.2022.3415
    2545
    PDF: 1256
    HTML: 64
  • Localization of avβ6 integrin-TGF-β1/Smad3, mTOR and PPARγ in experimental colorectal fibrosis

    G. Latella, A. Vetuschi, R. Sferra, S. Speca, E. Gaudio
    e40
    04-12-2013
    https://doi.org/10.4081/ejh.2013.e40
    3831
    PDF: 1068
    HTML: 638
  • Senescence-associated ß-galactosidase staining over the lifespan differs in a short- and a long-lived fish species

    Simon Schöfer, Sylvia Laffer, Stefanie Kirchberger, Michael Kothmayer, Renate Löhnert, Elmar E. Ebner, Klara Weipoltshammer, Martin Distel, Oliver Pusch, Christian Schöfer
    29-02-2024
    https://doi.org/10.4081/ejh.2024.3977
    2343
    PDF: 1292
    Supplementary: 123
    HTML: 230
  • Expression of Ser729 phosphorylated PKCepsilon in experimental crescentic glomerulonephritis: an immunohistochemical study

    V.N. Karavana, H. Gakiopoulou, E.A. Lianos
    15-04-2014
    https://doi.org/10.4081/ejh.2014.2308
    2264
    PDF: 979
    HTML: 650
  • Interaction between sphingosine kinase/sphingosine 1 phosphate and transforming growth factor-β/Smads pathways in experimental intestinal fibrosis. An in vivo immunohistochemical study

    Roberta Sferra, Simona Pompili, Luca Ventura, Caroline Dubuquoy, Silvia Speca, Eugenio Gaudio, Giovanni Latella, Antonella Vetuschi
    31-07-2018
    https://doi.org/10.4081/ejh.2018.2956
    2048
    PDF: 1026
    Supplementary: 229
    HTML: 49
  • Aortic dissection is associated with reduced polycystin-1 expression, an abnormality that leads to increased ERK phosphorylation in vascular smooth muscle cells

    J. Feng, S. Ge, L. Zhang, H. Che, C. Liang
    16-12-2016
    https://doi.org/10.4081/ejh.2016.2711
    2697
    PDF: 1178
    HTML: 315
  • Subcellular localization and distribution of the reduced folate carrier in normal rat tissues

    M. Hinken, S. Halwachs, C. Kneuer, W. Honscha
    e3
    27-01-2011
    https://doi.org/10.4081/ejh.2011.e3
    1969
    PDF: 759
    HTML: 5832
  • Optimization of the tartrate-resistant acid phosphatase detection by histochemical method

    M. J. Galvão, A. Santos, M. D. Ribeiro, A. Ferreira, F. Nolasco
    e1
    18-02-2011
    https://doi.org/10.4081/ejh.2011.e1
    1623
    PDF: 753
    HTML: 897
  • Energy Dispersive X-ray (EDX) microanalysis: A powerful tool in biomedical research and diagnosis

    Manuel Scimeca, Simone Bischetti, Harpreet Kaur Lamsira, Rita Bonfiglio, Elena Bonanno
    15-03-2018
    https://doi.org/10.4081/ejh.2018.2841
    15652
    PDF: 7378
    HTML: 539
  • Effect of Danggui Buxue decoction on hypoxia-induced injury of retinal Müller cells in vitro

    Xilin Ge, Caoxin Huang, Wenting Chen, Chen Yang, Wenfang Huang, Jia Li, Shuyu Yang
    25-11-2024
    https://doi.org/10.4081/ejh.2024.4140
    2169
    PDF: 730
    HTML: 34
  • Nuclear factor-kB and nitric oxide synthases in red blood cells: good or bad in obesity? A preliminary study

    Monika Široká, Caterina Franco, Zuzana Guľašová, Zdenka Hertelyová, Vladimíra Tomečková, Luigi F. Rodella, Rita Rezzani
    21-01-2020
    https://doi.org/10.4081/ejh.2020.3081
    1851
    PDF: 893
    HTML: 24
  • Dipeptidylpeptidase-­IV, a key enzyme for the degradation of incretins and neuropeptides: activity and expression in the liver of lean and obese rats

    E. Tarantola, V. Bertone, G. Milanesi, E. Capelli, A. Ferrigno, D. Neri, M. Vairetti, S. Barni, I. Freitas
    e41
    08-10-2012
    https://doi.org/10.4081/ejh.2012.e41
    1826
    PDF: 915
    HTML: 1093
  • Colchicine alleviates severe acute pancreatitis in rats by inhibiting acinar cell ferroptosis via LCN2/MAPK/ERK signaling axis

    Liu Yang, Xiaoyi Zheng, Yang Zhang, Yue Li, Lei Li, Feng Liu
    11-05-2026
    https://doi.org/10.4081/ejh.2026.4557
    455
    PDF: 643
    Supplementary: 50
    HTML: 8
  • Histochemical characterization of TDAG51 in endothelial remodeling and angiogenesis following myocardial infarction via PI3K-AKT signaling

    Kaizheng Liu, Jinyu Pan, Quan Liu, Yang Huang, Liqun Shang, Yi Zhang, Jinming Wen, Huayang Li, Zhongkai Wu
    15-06-2026
    https://doi.org/10.4081/ejh.2026.4569
    197
    PDF: 173
    HTML: 7
  • Angiotensin II: immunohistochemical study in Sardinian pterygium

    P. Demurtas, M. Corrias, I. Zucca, C. Maxia, F. Piras, P. Sirigu, M.T. Perra
    28-07-2014
    https://doi.org/10.4081/ejh.2014.2426
    2228
    PDF: 818
    HTML: 367
  • The expression of Sirtuins 1 and 4 in peripheral blood leukocytes from patients with type 2 diabetes

    R. Song, W. Xu, Y. Chen, Z. Li, Y. Zeng, Y. Fu
    e10
    21-03-2011
    https://doi.org/10.4081/ejh.2011.e10
    2146
    PDF: 702
    HTML: 981
  • Altered alkaline phosphatase activity in obese Zucker rats liver respect to lean Zucker and Wistar rats discussed in terms of all putative roles ascribed to the enzyme

    V. Bertone, E. Tarantola, A. Ferrigno, E. Gringeri, S. Barni, M. Vairetti, I. Freitas
    e5
    08-02-2011
    https://doi.org/10.4081/ejh.2011.e5
    1533
    PDF: 833
    HTML: 3577
  • Forever particles: histochemistry in the plasticene age

    Beatrice Camia, Andrea Casasco, Manuela Monti
    01-08-2025
    https://doi.org/10.4081/ejh.2025.4226
    1520
    PDF: 649
    HTML: 62
  • Immunolocalization of endocan during the endothelial-mesenchymal transition process

    L. M. Carrillo, E. Arciniegas, H. R. Rojas, R. E. Ramirez
    e13
    01-06-2011
    https://doi.org/10.4081/ejh.2011.e13
    1485
    PDF: 603
    HTML: 1395
  • Dipeptidylpeptidase-IV activity and expression reveal decreased damage to the intrahepatic biliary tree in fatty livers submitted to subnormothermic machine-perfusion respect to conventional cold storage

    E. Tarantola, V. Bertone, G. Milanesi, C. Gruppi, A. Ferrigno, M. Vairetti, S. Barni, I. Freitas
    17-07-2014
    https://doi.org/10.4081/ejh.2014.2414
    1945
    PDF: 857
    HTML: 576
  • Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells

    Huina Su, Ruiqiong Ma, Dehui Su, Cheng Tan, Ye Zhu, Xin Yang
    21-04-2026
    https://doi.org/10.4081/ejh.2026.4537
    985
    PDF: 614
    HTML: 22
  • Immunohistochemical detection of putative pathogenetic factors in adhesions of infants: a pilot study

    Arvis Pauliņš, Anna Junga, Māra Pilmane
    10-02-2026
    https://doi.org/10.4081/ejh.2026.4438
    333
    PDF: 466
    HTML: 12
  • Histochemistry as a versatile research toolkit in biological research, not only an applied discipline in pathology

    Carlo Pellicciari
    21-12-2018
    https://doi.org/10.4081/ejh.2018.3006
    2212
    PDF: 835
    HTML: 32
  • HLA-G expression and role in advanced-stage classical Hodgkin lymphoma

    G. Caocci, M. Greco, D. Fanni, G. Senes, R. Littera, S. Lai, P. Risso, C. Carcassi, G. Faa, G. La Nasa
    11-04-2016
    https://doi.org/10.4081/ejh.2016.2606
    2754
    PDF: 887
    HTML: 239
  • Swertianolin ameliorates immune dysfunction in sepsis via blocking the immunosuppressive function of myeloid-derived suppressor cells

    Zongfang Ren, Haoren Tang, Linjun Wan, Xing Liu, Ning Tang, Lingling Wang, Zhenhui Guo
    01-09-2021
    https://doi.org/10.4081/ejh.2021.3292
    1599
    PDF: 1060
    HTML: 41
  • Adipose-derived stem cells promote the recovery of intestinal barrier function by inhibiting the p38 MAPK signaling pathway

    Mei Yang, Wangbin Xu, Chaofu Yue, Rong Li, Xian Huang, Yongjun Yan, Qinyong Yan, Shisheng Liu, Yuan Liu, Qiaolin Li
    21-01-2025
    https://doi.org/10.4081/ejh.2025.4158
    1941
    PDF: 646
    Supplementary Figure: 113
    HTML: 63
  • Inhibition of fibrous adhesion formation in the temporomandibular joint of tenascin-C knockout mice

    Y. Shinohara, K. Okamoto, Y. Goh, N. Kiga, I. Tojyo, S. Fujita
    22-10-2014
    https://doi.org/10.4081/ejh.2014.2337
    2999
    PDF: 994
    HTML: 505
  • VEGF promotes diabetic retinopathy by upregulating the PKC/ET/NF-κB/ICAM-1 signaling pathway

    Meiying Zhang, Min Zhou, Xia Cai, Yan Zhou, Xueling Jiang, Yan Luo, Yue Hu, Rong Qiu, Yanrong Wu, Yuejin Zhang, Yan Xiong
    27-10-2022
    https://doi.org/10.4081/ejh.2022.3522
    2612
    PDF: 1093
    HTML: 49
  • Activation of the renin-angiotensin system in mice aggravates mechanical loading-induced knee osteoarthritis

    Kotaro Yamagishi, Ichiro Tsukamoto, Fumihisa Nakamura, Kazuhiko Hashimoto, Kazuhiro Ohtani, Masao Akagi
    24-07-2018
    https://doi.org/10.4081/ejh.2018.2930
    2075
    PDF: 1139
    HTML: 166
  • miR-129-5p regulates HMGB1/RAGE axis to inhibit pyroptosis and ameliorate cervical epithelial cell deterioration

    Huafang Wang, Dilidaer Sidike, Pan Liu, Longge Suo, Huerxidan Niyazi
    23-09-2025
    https://doi.org/10.4081/ejh.2025.4238
    514
    PDF: 468
    HTML: 16
  • Neurodegeneration in zebrafish embryos and adults after cadmium exposure

    Antonio Monaco, Teresa Capriello, Maria C. Grimaldi, Valentina Schiano, Ida Ferrandino
    19-10-2017
    https://doi.org/10.4081/ejh.2017.2833
    3405
    PDF: 1365
    HTML: 158
  • Histochemistry as an irreplaceable approach for investigating functional cytology and histology

    C. Pellicciari
    e41
    19-12-2013
    https://doi.org/10.4081/ejh.2013.e41
    3448
    PDF: 962
    HTML: 413
  • Human equilibrative nucleoside transporter 1 and carcinoma of the ampulla of Vater: expression differences in tumour histotypes

    G. Perrone, S. Morini, D. Santini, C. Rabitti, B. Vincenzi, R. Alloni, A. Antinori, P. Magistrelli, R. Lai, C. Cass, J. R. Mackey, R. Coppola, G. Tonini, A. Onetti Muda
    e38
    13-09-2010
    https://doi.org/10.4081/ejh.2010.e38
    1535
    PDF: 749
    HTML: 1771
  • Expression and role of cocaine-amphetamine regulated transcript (CART) in the proliferation of biliary epithelium

    Arianna Casini, Giorgio Vivacqua, Rosa Vaccaro, Anastasia Renzi, Stefano Leone, Luigi Pannarale, Antonio Franchitto, Paolo Onori, Romina Mancinelli, Eugenio Gaudio
    19-10-2023
    https://doi.org/10.4081/ejh.2023.3846
    1846
    PDF: 694
    HTML: 35
  • Leptin affects filopodia and cofilin in NK-92 cells in a dose- and time-dependent manner

    Jana Oswald, Maximilian Büttner, Simon Jasinski-Bergner, Roland Jacobs, Philip Rosenstock, Heike Kielstein
    26-01-2018
    https://doi.org/10.4081/ejh.2018.2848
    3412
    PDF: 1259
    HTML: 125
  • Maresin 1 alleviates myocardial ischemia-reperfusion injury in rats by suppressing inflammation

    Hongkai Xiao, Jinghu Liu, Qinhong Cai, Siyu Liang, Zhitao Hu, Xiaochao Chen
    13-10-2025
    https://doi.org/10.4081/ejh.2025.4254
    899
    PDF: 463
    HTML: 44
  • Twenty years of histochemistry in the third millennium, browsing the scientific literature

    Carlo Pellicciari
    29-12-2020
    https://doi.org/10.4081/ejh.2020.3213
    1455
    PDF: 566
    HTML: 17
  • Aberrant DKK3 expression in the oral leukoplakia and oral submucous fibrosis: a comparative immunohistochemical study

    T. Al-dhohorah, M. Mashrah, Z. Yao, J. Huang
    16-06-2016
    https://doi.org/10.4081/ejh.2016.2629
    2823
    PDF: 893
    HTML: 351
  • Growth hormone inhibits the JAK/STAT3 pathway by regulating SOCS1 in endometrial cells in vitro: a clue to enhance endometrial receptivity in recurrent implantation failure

    Haixia Li, Ning Sun, Yaqiao Zhu, Wei Wang, Meihong Cai, Xiaohuan Luo, Wei Xia, Song Quan
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3580
    1756
    PDF: 1030
    HTML: 52
  • Epidermal growth factor-like domain multiple 7 (EGFL7): Expression and possible effect on biliary epithelium growth in cholangiocarcinoma

    Caterina L. Mammola, Antonella Vetuschi, Luigi Pannarale, Roberta Sferra, Romina Mancinelli
    30-11-2018
    https://doi.org/10.4081/ejh.2018.2971
    1497
    PDF: 828
    Supplementary: 199
    HTML: 32
  • Histochemistry through the years, browsing a long-established journal: novelties in traditional subjects

    C. Pellicciari
    e51
    16-12-2010
    https://doi.org/10.4081/ejh.2010.e51
    1595
    PDF: 780
    HTML: 4061
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European Journal of Histochemistry

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pISSN: 1121-760X
eISSN: 2038-8306

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