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European Journal of Histochemistry

eISSN 2038-8306 - pISSN 1121-760X

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Editor-in-Chief: Marco Biggiogera, Italy

1.9
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1.9
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  • Porphyromonas gingivalis lipopolysaccharide stimulation in human periodontal ligament stem cells: role of epigenetic modifications to the inflammation

    Francesca Diomede, Soundara Rajan Thangavelu, Ilaria Merciaro, Monica D'Orazio, Placido Bramanti, Emanuela Mazzon, Oriana Trubiani
    25-08-2017
    https://doi.org/10.4081/ejh.2017.2826
    3150
    PDF: 1325
    HTML: 144
  • MALAT1 regulates hypertrophy of cardiomyocytes by modulating the miR-181a/HMGB2 pathway

    Feng Chen, Wenfeng Li, Dandan Zhang, Youlin Fu, Wenjin Yuan, Gang Luo, Fuwei Liu, Jun Luo
    21-06-2022
    https://doi.org/10.4081/ejh.2022.3426
    1513
    PDF: 862
    HTML: 30
  • Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model

    Juan Fan, Yu Ma, Liying Sun, Suhua Miao, Jianghong He
    20-04-2026
    https://doi.org/10.4081/ejh.2026.4533
    492
    PDF: 275
    HTML: 14
  • Metallothionein expression and synthesis in the testis of the lizard Podarcis sicula under natural conditions and following estrogenic exposure

    Mariailaria Verderame, Ermelinda Limatola, Rosaria Scudiero
    03-05-2017
    https://doi.org/10.4081/ejh.2017.2777
    2045
    PDF: 734
    HTML: 163
  • DPY30 promotes the growth and survival of osteosarcoma cell by regulating the PI3K/AKT signal pathway

    Gong Cheng, Fengmin An, Zhilin Cao, Mingdi Zheng, Zhongyuan Zhao, Hao Wu
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3413
    1344
    PDF: 671
    Supplementary: 112
    HTML: 36
  • The lncRNA MEG3 promotes trophoblastic cell growth and invasiveness in preeclampsia by acting as a sponge for miR-21, which regulates BMPR2 levels

    Huyi Liu, Xiangdao Cai , Jia Liu, Fengxiang Zhang , Andong He, Ruiman Li
    25-11-2021
    https://doi.org/10.4081/ejh.2021.3323
    1968
    PDF: 717
    HTML: 35
  • Histochemistry for nucleic acid research: 60 years in the European Journal of Histochemistry

    Claudio Casali, Stella Siciliani, Lorena Zannino, Marco Biggiogera
    20-04-2022
    https://doi.org/10.4081/ejh.2022.3409
    1861
    PDF: 960
    HTML: 31
  • Ultrastructural immunocytochemistry shows impairment of RNA pathways in skeletal muscle nuclei of old mice: A link to sarcopenia?

    Maria Assunta Lacavalla, Barbara Cisterna, Carlo Zancanaro, Manuela Malatesta
    24-03-2021
    https://doi.org/10.4081/ejh.2021.3229
    2116
    PDF: 748
    HTML: 21
  • DNMT1 regulates IL-6- and TGF-β1-induced epithelial mesenchymal transition in prostate epithelial cells

    Hui Xu, Yanbo Chen, Qi Chen, Huan Xu, Yanxia Wang, Jiao Yu, Juan Zhou, Zhong Wang, Bing Xu
    03-05-2017
    https://doi.org/10.4081/ejh.2017.2775
    2719
    PDF: 1060
    HTML: 185
  • The Bromodomain testis-specific gene (Brdt) characterization and expression in gilthead seabream, Sparus aurata, and European seabass, Dicentrarchus labrax

    M. Úbeda-Manzanaro, J.B. Ortiz-Delgado, C. Sarasquete
    02-05-2016
    https://doi.org/10.4081/ejh.2016.2638
    1776
    PDF: 856
    HTML: 337
  • miR-1270 enhances the proliferation, migration, and invasion of osteosarcoma via targeting cingulin

    Yang Liu, Weichun Guo, Shuo Fang, Bin He, Xiaohai Li, Li Fan
    07-12-2021
    https://doi.org/10.4081/ejh.2021.3237
    1751
    PDF: 596
    HTML: 27
  • High WTAP expression level as a promising biomarker for poor prognosis in colorectal cancer: a pilot study

    Michela Relucenti, Claudia Tito, Paolo Mercantini, Emanuela Pilozzi, Claudio Barbaranelli, Loredana Cristiano, Daniela Savarese, Daniela Bastianelli, Francesco Fazi, Vincenzo Petrozza, Xiaobo Li, Rui Chen, Selenia Miglietta, Giuseppe Familiari
    16-12-2024
    https://doi.org/10.4081/ejh.2024.4145
    1432
    PDF: 597
    HTML: 9
  • SUSD2 suppresses lung adenocarcinoma tumorigenesis by inducing autophagy via inhibiting PI3K/AKT/mTOR signaling pathway

    Shengwen Wang, Gang Yang, Qian Zhang, Yanbei Zhang
    18-05-2026
    https://doi.org/10.4081/ejh.2026.4544
    202
    PDF: 174
    Supplementary: 25
    HTML: 7
  • Propofol alleviates M1 polarization and neuroinflammation of microglia in a subarachnoid hemorrhage model in vitro, by targeting the miR-140-5p/TREM-1/NF-κB signaling axis

    Lan Wang, Zhenyu Fan, Haijin Wang, Shougui Xiang
    17-09-2024
    https://doi.org/10.4081/ejh.2024.4034
    1250
    PDF: 657
    HTML: 13
  • Cytoplasmic lattices are not linked to mouse 2-cell embryos developmental arrest

    Marianna Longo, Michele Boiani, CarloAlberto Redi, Manuela Monti
    24-09-2018
    https://doi.org/10.4081/ejh.2018.2972
    2575
    PDF: 980
    HTML: 40
  • Nuclear damages and oxidative stress: new perspectives for laminopathies

    G. Lattanzi, S. Marmiroli, A. Facchini, N.M. Maraldi
    e45
    18-10-2012
    https://doi.org/10.4081/ejh.2012.e45
    2103
    PDF: 962
    HTML: 206
  • Seasonal expressions of androgen receptor, estrogen receptors and cytochrome P450 aromatase in the uteri of the wild Daurian ground squirrels (Spermophilus dauricus)

    Yu Wang, Ziyi Wang, Wenyang Yu, Xia Sheng, Haolin Zhang, Yingying Han, Zhengrong Yuan, Qiang Weng
    07-02-2018
    https://doi.org/10.4081/ejh.2018.2889
    2177
    PDF: 613
    HTML: 66
  • Growth hormone inhibits the JAK/STAT3 pathway by regulating SOCS1 in endometrial cells in vitro: a clue to enhance endometrial receptivity in recurrent implantation failure

    Haixia Li, Ning Sun, Yaqiao Zhu, Wei Wang, Meihong Cai, Xiaohuan Luo, Wei Xia, Song Quan
    22-12-2022
    https://doi.org/10.4081/ejh.2023.3580
    1706
    PDF: 997
    HTML: 50
  • Oocytes - Maternal Information and Functions

    Oocytes - Maternal Information and Functions

    Manuela Monti
    18-09-2017
    https://doi.org/10.4081/ejh.2017.2849
    1619
    PDF: 759
    HTML: 50
  • The possible prognostic role of histone deacetylase and transforming growth factor β/Smad signaling in high grade gliomas treated by radio-chemotherapy: a preliminary immunohistochemical study

    Roberta Sferra, Simona Pompili, Claudio Festuccia, Francesco Marampon, Giovanni L. Gravina, Luca Ventura, Ernesto Di Cesare, Sara Cicchinelli, Eugenio Gaudio, Antonella Vetuschi
    16-05-2017
    https://doi.org/10.4081/ejh.2017.2732
    2738
    PDF: 1067
    HTML: 156
  • miR-126 targeting GOLPH3 inhibits the epithelial-mesenchymal transition of gastric cancer BGC-823 cells and reduces cell invasion

    Jiancai Ouyang, Fuhu Song, He Li, Rui Yang, Haicheng Huang
    28-10-2020
    https://doi.org/10.4081/ejh.2020.3168
    1507
    PDF: 649
    HTML: 27
  • Spinosin ameliorates osteoarthritis through enhancing the Nrf2/HO-1 signaling pathway

    Peipei Lu, Shuxiang Li, Caoyang Zhang, Xinyi Jiang, Jinghua Xiang, Hong Xu, Jian Dong, Kun Wang, Yuhua Shi
    22-05-2024
    https://doi.org/10.4081/ejh.2024.4033
    1285
    PDF: 552
    HTML: 19
  • Activation of Hedgehog pathway by circEEF2/miR-625-5p/TRPM2 axis promotes prostate cancer cell proliferation through mitochondrial stress

    ChenHui Zhu, LiJuan Lin, ChangQing Huang, ZhiHui Wu
    11-11-2024
    https://doi.org/10.4081/ejh.2024.4063
    1661
    PDF: 593
    HTML: 22
  • Stem Cells & Regenerative Medicine - From molecular embryology to tissue engineering

    Carlo Alberto Redi
    br8
    15-09-2011
    https://doi.org/10.4081/ejh.2011.br8
    1092
    PDF: 491
    HTML: 295
  • Interindividual variability in the expression of surfactant protein A and B in the human lung during development

    F. Cau, E. Pisu, C. Gerosa, G. Senes, F. Ronchi, C. Botta, E. Di Felice, F. Uda, V. Marinelli, G. Faa, V. Fanos, C. Moretti, D. Fanni
    26-09-2016
    https://doi.org/10.4081/ejh.2016.2678
    2087
    PDF: 798
    Supplementary: 268
    HTML: 387
  • <a href="https://it.freepik.com/vettori/sfondo">Sfondo vettore creata da pikisuperstar - it.freepik.com</a>

    DNA damage and repair in differentiation of stem cells and cells of connective cell lineages: A trigger or a complication?

    Nikolajs Sjakste, Una Riekstiņa
    03-05-2021
    https://doi.org/10.4081/ejh.2021.3236
    3302
    PDF: 1430
    HTML: 90
  • Ciliary neurotrophic factor (CNTF) and its receptor (CNTFRα) signal through MAPK/ERK pathway in human prostate tissues: a morphological and biomolecular study

    Sonia Fantone, Giovanni Tossetta, Rodolfo Montironi, Martina Senzacqua , Daniela Marzioni, Roberta Mazzucchelli
    19-10-2020
    https://doi.org/10.4081/ejh.2020.3147
    2170
    PDF: 817
    HTML: 23
  • Novel understanding on genetic mechanisms of enteric neuropathies leading to severe gut dysmotility

    Francesca Bianco, Giulia Lattanzio, Luca Lorenzini, Chiara Diquigiovanni, Maurizio Mazzoni, Paolo Clavenzani, Laura Calzà, Luciana Giardino, Catia Sternini, Elena Bonora, Roberto De Giorgio
    25-11-2021
    https://doi.org/10.4081/ejh.2021.3289
    2527
    PDF: 1385
    HTML: 57
  • Sarcoglycan complex in masseter and sternocleidomastoid muscles of baboons: an immunohistochemical study

    G. Cutroneo, A. Centofanti, F. Speciale, G. Rizzo, A. Favaloro, G. Santoro, D. Bruschetta, D. Milardi, A. Micali, D. Di Mauro, G. Vermiglio, G. Anastasi, F. Trimarchi
    05-06-2015
    https://doi.org/10.4081/ejh.2015.2509
    2121
    PDF: 660
    HTML: 457
  • Seasonal expressions of GPR41 and GPR43 in the colon of the wild ground squirrels (Spermophilus dauricus)

    Xiaoying Yang, Xuhao Liu, Fengcheng Song, Hao Wei, Fuli Gao, Haolin Zhang, Yingying Han, Qiang Weng, Zhengrong Yuan
    21-01-2022
    https://doi.org/10.4081/ejh.2022.3351
    1927
    PDF: 876
    HTML: 37
  • The role of miRNA-29b1 on the hypoxia-induced apoptosis in mammalian cardiomyocytes

    Bo Dai, Hailin Liu, Dingmin Juan, Kaize Wu, Ruhao Cao
    27-06-2024
    https://doi.org/10.4081/ejh.2024.4021
    1083
    PDF: 565
    HTML: 32
  • Ozone at low concentrations does not affect motility and proliferation of cancer cells in vitro

    Manuela Costanzo, Alessandro Romeo, Barbara Cisterna, Laura Calderan, Paolo Bernardi, Viviana Covi, Gabriele Tabaracci, Manuela Malatesta
    02-04-2020
    https://doi.org/10.4081/ejh.2020.3119
    1490
    PDF: 882
    HTML: 32
  • Benzo[a]pyrene impairs the migratory pattern of human gonadotropin-releasing-hormone-secreting neuroblasts

    Giulia Guarnieri, Matteo Becatti, Paolo Comeglio, Linda Vignozzi, Mario Maggi, Gabriella Barbara Vannelli, Annamaria Morelli
    13-08-2021
    https://doi.org/10.4081/ejh.2021.3282
    1542
    PDF: 595
    HTML: 21
  • The selective blockade of metabotropic glutamate receptor-5 attenuates fat accumulation in an in vitro model of benign steatosis

    Andrea Ferrigno, Clarissa Berardo, Laura Giuseppina Di Pasqua, Marta Cagna, Veronica Siciliano, Plinio Richelmi, Mariapia Vairetti
    10-11-2020
    https://doi.org/10.4081/ejh.2020.3175
    1931
    PDF: 987
    Supplementary: 197
    HTML: 33
  • Folic acid promotes autophagy to relieve metabolism-associated fatty liver disease by regulating NRF2

    Yu Wen, Juan Luo, Chunjing Shi, Jie Wu
    03-11-2025
    https://doi.org/10.4081/ejh.2025.4309
    931
    PDF: 576
    HTML: 36
  • In vitro reparative dentin: a biochemical and morphological study

    G. Teti, V. Salvatore, A. Ruggeri, L. Manzoli, M. Gesi, G. Orsini, M. Falconi
    e23
    06-08-2013
    https://doi.org/10.4081/ejh.2013.e23
    3324
    PDF: 870
    HTML: 940
  • Histochemical characterization of TDAG51 in endothelial remodeling and angiogenesis following myocardial infarction via PI3K-AKT signaling

    Kaizheng Liu, Jinyu Pan, Quan Liu, Yang Huang, Liqun Shang, Yi Zhang, Jinming Wen, Huayang Li, Zhongkai Wu
    15-06-2026
    https://doi.org/10.4081/ejh.2026.4569
    123
    PDF: 133
    HTML: 1
  • MicroRNA-29b-3p promotes 5-fluorouracil resistance via suppressing TRAF5-mediated necroptosis in human colorectal cancer

    Shuimei Wu, Yun Zhou, Ping Liu, Hui Zhang, Wanliang Wang, Yuan Fang, Xiang Shen
    22-06-2021
    https://doi.org/10.4081/ejh.2021.3247
    2115
    PDF: 1041
    Supplementary: 208
    HTML: 21
  • Characterization of PD-1/PD-L1 immune checkpoint expression in soft tissue sarcomas

    Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Masao Akagi
    02-07-2021
    https://doi.org/10.4081/ejh.2021.3203
    3187
    PDF: 971
    HTML: 37
  • Aberrant DKK3 expression in the oral leukoplakia and oral submucous fibrosis: a comparative immunohistochemical study

    T. Al-dhohorah, M. Mashrah, Z. Yao, J. Huang
    16-06-2016
    https://doi.org/10.4081/ejh.2016.2629
    2782
    PDF: 871
    HTML: 348
  • Aortic dissection is associated with reduced polycystin-1 expression, an abnormality that leads to increased ERK phosphorylation in vascular smooth muscle cells

    J. Feng, S. Ge, L. Zhang, H. Che, C. Liang
    16-12-2016
    https://doi.org/10.4081/ejh.2016.2711
    2665
    PDF: 1150
    HTML: 312
  • Solamargine inhibited the progression of non-small cell lung cancer in vitro by activating T cells

    Changchun Zhang, Yichen Sun, Wei Jiang, Lin Wu, Qi Fang, Qikun Wang
    01-09-2025
    https://doi.org/10.4081/ejh.2025.4217
    552
    PDF: 230
    HTML: 11
  • Overexpression of MYBL2 predicts poor prognosis and promotes oncogenesis in endometrial carcinoma

    Lulu Le, Ji Luo, Haifang Wu, Ling Chen, Xiaoli Tang, Fen Fu
    30-03-2021
    https://doi.org/10.4081/ejh.2021.3226
    2114
    PDF: 894
    Supplementary: 200
    HTML: 31
  • Effects of the lncRNA ENST00000623984 on colon cancer and the biological characteristics of colon cancer cells

    Zhi-bao Liu, Jing-hua Zhang, Jing-hua Gao, Jian Shi
    12-07-2021
    https://doi.org/10.4081/ejh.2021.3215
    2247
    PDF: 580
    HTML: 31
  • Possible involvement of DNA strand breaks in regulation of cell differentiation

    N Sjakste, T Sjakste
    81-94
    10-08-2009
    https://doi.org/10.4081/1129
    546
    PDF: 2162
  • Immunohistochemical study of doublecortin and nucleostemin in canine brain

    E. De Nevi, P. Marco-Salazar, D. Fondevila, E. Blasco, L. Pérez, M. Pumarola
    e9
    20-03-2013
    https://doi.org/10.4081/ejh.2013.e9
    2648
    PDF: 764
    HTML: 283
  • Apigenin induces dermal collagen synthesis via smad2/3 signaling pathway

    Y. Zhang, J. Wang, X. Cheng, B. Yi, X. Zhang, Q. Li
    13-04-2015
    https://doi.org/10.4081/ejh.2015.2467
    4494
    PDF: 1643
    HTML: 897
  • Three dimensional analysis of histone methylation patterns in normal and tumor cell nuclei

    M Cremer, R Zinner, S Stein, H Albiez, B Wagler, C Cremer, T Cremer
    15-28
    29-06-2009
    https://doi.org/10.4081/855
    537
    PDF: 514
  • P15 | PHB/JAK/H3Y41PH AXIS REGULATES MEIOTIC RECOMBINATION IN SPERMATOGENESIS H. Chen1, L. Zhang1, W. Tan-Tai1, M. Liu2, H. Shi3, W. O4, P.A. Martin-DeLeon5 | 1Department of Anatomy, Histology & Embryology, Shanghai Medical College, Fudan University, Shanghai, China; 2State Key Laboratory of Molecular Biology, Chinese Academy of Sciences-University of Chinese Academy of Sciences, Shanghai, China; 3NHC Key Lab of Reproduction Regulation, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai, China; 4School of Biomedical Sciences, The University of Hong Kong, Hong Kong SAR, China; 5Department of Biological Sciences, University of Delaware, Newark, USA

    21-08-2025
    https://doi.org/10.4081/ejh.2025.4335
    184
  • Structural and functional alterations of the cell nucleus in skeletal muscle wasting: the evidence in situ

    M. Malatesta, G. Meola
    e44
    19-10-2010
    https://doi.org/10.4081/ejh.2010.e44
    1570
    PDF: 634
    HTML: 621
  • Low ozone concentrations promote in vitro preservation of explanted articular cartilage: an ultrastructural study

    Giada Remoli, Chiara Rita Inguscio, Federico Boschi, Gabriele Tabaracci, Manuela Malatesta, Barbara Cisterna
    26-01-2026
    https://doi.org/10.4081/ejh.2026.4440
    1268
    PDF: 254
    HTML: 13
  • Muc5ac mucin expression during rat skin development

    V. Ferretti, Á. Segal-Eiras, C.G. Barbeito, M.V. Croce
    20-02-2015
    https://doi.org/10.4081/ejh.2015.2462
    2544
    PDF: 859
    HTML: 721
  • 08 | HUMAN ADIPOSE STEM CELLS: IMPACT OF DONORS’ AGE ON CELL PROPERTIES AND BEHAVIOUR Ludovica Barone1, Federica Rossi1, Federico Tamborini1, Christina Pagiatakis1|2, Roberto Papait1|2, Rosalba Gornati1 | 1Dept of Biotechnology and Life Sciences, University of Insubria, Varese, Italy; 2Dept of Cardiovascular Medicine, IRCCS Humanitas Research Hospital, Rozzano (MI), Italy

    GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
    22-06-2026
    https://doi.org/10.4081/ejh.2026.4626
    185
    PDF: 29
  • Immunohistochemical markers of neural progenitor cells in the early embryonic human cerebral cortex

    L. Vinci, A. Ravarino, V. Fanos, A.G. Naccarato, G. Senes, C. Gerosa, G. Bevilacqua, G. Faa, R. Ambu
    01-02-2016
    https://doi.org/10.4081/ejh.2016.2563
    4661
    PDF: 2496
    HTML: 1617
  • The substance P and neurokinin-1 receptor system in human thyroid cancer: an immunohistochemical study

    Inmaculada Isorna, Francisco Esteban, Juan Solanellas, Rafael Coveñas, Miguel Muñoz
    28-04-2020
    https://doi.org/10.4081/ejh.2020.3117
    1408
    PDF: 740
    HTML: 12
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Vol. 70 No. 2 (2026)
Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice
Nana Bao et al.
20 April 2026
Vol. 70 No. 2 (2026)
Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells
Huina Su et al.
21 April 2026
Vol. 70 No. 2 (2026)
Electroacupuncture combined with rTMS promotes neuronal regeneration via DNMT1-mediated PI3K-AKT pathway in cerebral palsy model
Juan Fan et al.
20 April 2026

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European Journal of Histochemistry

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