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Fine structural detection of calcium ions by photoconversion
1717PDF: 742Supplementary: 296HTML: 138 -
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Histochemistry for nanomedicine: Novelty in tradition
1085PDF: 460HTML: 18 -
FLOW CYTOMETRY IN THE DEVELOPMENT AND CHARACTERIZATION OF PRECLINICAL TUMOR MODELS BASED ON THE ANALYSIS OF EXTRACELLULAR VESICLES AS CANDIDATE LIQUID BIOMARKERS I. D’Agnano | Institute of Biomedical Technologies, CNR, Segrate, Milan, Italy
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P78 | THE ROLE OF EXTRACELLULAR VESICLES DERIVED FROM MESENCHYMAL STROMAL CELLS IN MYOFIBER REGENERATION A. Longhin1, V. Gatta2, G. Teti2, C. Sassoli3, F. Chellini3, A. Tani3, M. Parigi3, R. Garella3, F. Palmieri3, R. Squecco3, M. Mattioli Belmonte4, C. Licini4, A. La Contana4, S. Zecchi Orlandini3, M. Falconi1 | 1Dep. Medical and Surgical Sciences, University of Bologna, Bologna, Italy; 2Dep. Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy; 3Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; 4Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Italy
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LABELING EXTRACELLULAR VESICLES FOR HIGHLY SENSITIVE FLOW CYTOMETRY ANALYSES P. Simeone1,2, D. Brocco3, F. D’Ascanio1,2,4, D. De Bellis1,2, G. Colasante1,2, A. Aquilini-Mummolo1,2, T. Esmail1,2, A. Younas2, M. Filoso2, C. Cichella2, M. C. Cufaro5, A. Di Sebastiano5, D. Pieragostino6, S. Burattini7, M. Battistelli7, P. Del Boccio5, A. Fontana8, R. Di Pietro1, P. Lanuti1,2 | 1Department of Medicine and Aging Sciences, University “G. d’Annunzio” of Chieti-Pescara, Italy; 2Flow Cytometry Core Facility, Center for Advanced Studies and Technology (CAST), University “G. d’Annunzio” of Chieti-Pescara, Italy; 3Department of Medical, Oral and Biotechnological Sciences, G. d’Annunzio University of Chieti-Pescara, Chieti, Italy; 4Department of Humanities, Law and Economics, Leonardo da Vinci University, Torrevecchia Teatina, Italy: 5Department of Science, University “G. d’Annunzio”, Chieti Pescara, Italy; 6Department of Innovative Technologies in Medicine and Dentistry, G. d’Annunzio University of Chieti-Pescara, Italy; 7Department of Biomolecular Sciences, University of Urbino, Urbino, Italy; 8Department of Pharmacy, University “G. d’Annunzio”, Chieti Pescara, Italy
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SENSORY NEURON TOXICITY TRIGGERED BY ANTICANCER DRUGS IS COUNTERACTED BY EXTRACELLULAR VESICLES DERIVED FROM ADIPOSE-DERIVED MESENCHYMAL STEM CELLS D’Aprile C1, Naghshbandieh A1,3, Fabbro V1, Turano E2, Scambi I2, Virla F2, Caprioli M2, Mariotti R2, Scuteri A1 and Meregalli C1 | 1Experimental Neurology Unit and Milan Center for Neuroscience, School of Medicine and Surgery, University of Milano-Bicocca, Italy; 2Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Italy; 3PhD Program in Neuroscience, University of Milano- Bicocca, Italy
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Characterization of the role of RILP in cell migration
2454PDF: 948Supplementary: 242Movie 1: 331Movie 2: 374HTML: 102 -
ECRG4 expression in normal rat tissues: expression study and literature review
2915PDF: 1144Supplementary: 377HTML: 1013 -
NEUROPROTECTIVE POTENTIAL OF ADIPOSE MESENCHYMAL STEM CELL-DERIVED EXTRACELLULAR VESICLES ON DAMAGED MOTONEURONS Caprioli M1, Sganzerla D1, Scambi I1, Virla F1, Grazioli N2, Greco N2, Turano E1 and Mariotti R1 | 1Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Italy; 2Department of Engineering for Innovation Medicine, University of Verona, Italy
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P71 | THE EXTRACELLULAR VESICLE POPULATIONS UNDERWENT ALTERATIONS SUBSEQUENT TO THE PRETREATMENT OF ADIPOSE-DERIVED STEM CELLS WITH MELATONIN RECEPTOR AGONIST B. Sikora, K. Pogoda-Mieszczak, E. Bogunia, A. Skubis-Sikora, P. Czekaj | Department of Cytophysiology, Faculty of Medical Sciences in Katowice, Medical University of Silesia in Katowice, Poland
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Excitatory Amino Acid Transporter 5 is widely expressed in peripheral tissues
2920PDF: 733Supplementary: 234HTML: 435 -
P21 | EARLY BIOLOGICAL EFFECTS ON CELL PROLIFERATION AND DIFFERENTIATION INDUCED BY EXTRACELLULAR MICROVESICLES (EVS) DERIVED FROM HUMAN KERATINOCYTES IN PSORIATIC MICROENVIRONMENT D. Daluiso1, B. Barco1, C. Porro2, E. Donetti3, F. Riva1 | 1Department of Publich Health, Experimental and Forensic Medicine, Histology and Embryology Unit, University of Pavia, Pavia, Italy; 2Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy; 3Department of Biomedical Sciences for Health, University of Milan, Milan, Italy
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Is there still room for novelty, in histochemical papers?
2743PDF: 700HTML: 279 -
P28 | EXPLORING THE POTENTIAL LINK BETWEEN MITOCHONDRIAL DYSFUNCTION AND MITO-EVS IN PANCREATIC DUCTAL ADENOCARCINOMA (PDAC) V. Giansante1, L. Leanza2, E. Guerra3, F. Vianello4, C. Iacovino1, S. Lattanzio1, L. Morello1, G. Stati1, P. Simeone3, P. Lanuti3, S. Alberti5, M. Reichert6, R. Di Pietro1 | 1Department of Medicine and Ageing Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy; 2Department of Biology, University of Padua, Padua, Italy; 3Department of Medicine and Ageing Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy; Laboratory of Cancer Pathology, Center for Advanced Studies and Technology (CAST)G. d’Annunzio” University of Chieti-Pescara, Italy; 4Department of Biology, University of Padua, Padua, Italy; 5Unit of Medical Genetics, Department of Biomedical Sciences, University of Messina, Messina, Italy; 6Translational Pancreatic Cancer Research Center, Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany; Center for Organoid Systems (COS), Technical University of Munich, Garching, Germany
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SHORT-TERM EXPOSURE TO PARTICULATE MATTER TRIGGERS SELECTIVE MOLECULAR AND BEHAVIORAL ALTERATIONS IN A MOUSE MODEL OF MULTIPLE SCLEROSIS Bonato M1,2, Montarolo F1,2, Cerrato V1,2, Parolisi R1,2, Abbadessa G3, Caudana M3, Di Cintio N1,2, De Francia S3, Bertolotto A2,4, Buffo A1,2, and Boda E1,2 | 1Dept. of Neuroscience Rita Levi Montalcini, University of Turin, Turin, Italy; 2Neuroscience Institute Cavalieri Ottolenghi, Orbassano (Turin), Italy; 3Department of Clinical and Biological Sciences, University of Turin, Orbassano (Turin), Italy; 4Koelliker Hospital, Turin, Italy
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P13 | MORPHO-FUNCTIONAL DIFFERENCES IN THE GUT OF AGED MICE WITH THE POSSIBLE EFFECTS OF ANTI-INFLAMMATORY TREATMENTS A. Casini1, S. Leone1, R. Mancinelli1, R. Vaccaro1, M. Catalano2, G. D’Alessandro2, A. Rinaldi2, A. Reccagni2, G. Vivacqua3, A. Franchitto4, P. Onori1, C. Limatola2, E. Gaudio1 | 1Department of Anatomical, Histological, Forensic Medicine and Orthopaedics Sciences, Sapienza University of Rome, Italy; 2Department of Physiology and Pharmacology, Sapienza University of Rome, Italy; 3Department of Medicine and Surgery, University Campus BioMedico of Rome, Italy; 4Department of Movement, Human and Health Sciences, Division of Health Sciences, University of Rome «Foro Italico», Rome,Italy
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FLOW CYTOMETRY FOR THE ANALYSIS OF MICRO/ NANOPARTICLES: CURRENT APPLICATIONS AND CHALLENGES S. Amalfitano | National Research Council of Italy - Water Research Institute (CNR-IRSA) – Montelibretti, Rome, Italy
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EXPRESSION OF PIEZO1 IN CLEAR CELL RENAL CELL CARCINOMA: INSIGHTS FROM BIOINFORMATIC AND IMMUNOHISTOCHEMICAL ANALYSES D. Jerka1, P. Antosik2, K. Bonowicz1,3, D. Grzanka4, M. Gagat1,3 | 1Department of Histology and Embryology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Bydgoszcz, Poland; 2Department of Dermatology and Venerology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland; 3Faculty of Medicine, Collegium Medicum, Mazovian Academy in Płock, Płock, Poland; 4Department of Clinical Pathomorphology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland
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IMMUNOLOGICAL MECHANISMS IN REGENERATIVE MEDICINE: A LESSON FROM THE HUMAN PLACENTA O. Parolini1,2 | 1Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy; 2Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy
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TRACKING HER2 TRAFFICKING AND ORGANELLE CROSSTALK IN TRASTUZUMAB-DERUXTECAN–TREATED BREAST CANCER CELLS USING MULTIMODAL IMAGING E. Tagliatti1, M. C. Gagliani2, G. Bellese2, M. Crippa3, A. Abbona4, M. Paccagnella4, P. Arnaldi5, M. C. Merlano6, O. Garrone7, A.M. Porcelli8, M. Matteoli1, P. Falletta9, P. Castagnola10, K. Cortese2 | 1IRCCS Humanitas Research Hospital, Laboratory of Pharmacology and Brain Pathology, Rozzano, Milano, Italy; 2DIMES, Department of Experimental Medicine, Cellular Electron Microscopy Lab, University of Genoa, Genoa, Italy; 3Experimental Imaging Center, IRCCS Ospedale San Raffaele, Milan, Italy; 4Health Department S. Croce e Carle Teaching Hospital, Cuneo, Italy; 5IRCCS Ospedale Policlinico San Martino, Genova, Italy; 6Scientific Direction, Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy; 7Medical Oncology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy; 8FABIT, Department of Pharmacy and Biotechnology and CIRI, Interdepartmental Centre for Industrial Research ‘Scienze Della Vita e Tecnologie per La Salute’, University of Bologna, Bologna, Italy; 9Vita-Salute San Raffaele University, Milan, Italy; 10IRCCS Ospedale Policlinico San Martino, Genova, Italy
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DPY30 promotes the growth and survival of osteosarcoma cell by regulating the PI3K/AKT signal pathway
1203PDF: 623Supplementary: 96HTML: 24 -
P64 | EX VIVO EXTRACTION OF GLIOMA SECRETOME: A NOVEL MICROENVIRONMENT-BASED PROTOCOL FOR METABOLIC AND MOLECULAR PROFILING I. Neri1, M.V. Marvi1, V. Righi2, V. Papa3, E. Boschetti1, S. Blando1, E. Franceschi4, M. Zoli4, D. Mazzatenta4, N. Neri4, A. Vignaroli4, L. Cocco1, L. Manzoli1, S. Ratti1 | 1Cellular Signalling Laboratory, Anatomy Center, Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy; 2Department of Life Quality Sciences, University of Bologna, Bologna, Italy; 3IRCCS St. Orsola, Bologna, Italy; 4IRCCS Institute of Neurological Sciences of Bologna, Bologna, Italy
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