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Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou

06-08-2025

https://doi.org/10.4081/ejh.2025.4228

1456

PDF: 751

HTML: 25
Combination of tolvaptan and valsartan improves cardiac and renal functions in doxorubicin-induced heart failure in mice

Fengqin Yan, Hong Zhu, Yingxia He, Qinqin Wu, Xiaoyu Duan

11-11-2022

https://doi.org/10.4081/ejh.2022.3563

1880

PDF: 928

Supplementary: 153

HTML: 38
Independent and interactive roles of hirudin and HMGB1 interference in protecting renal function by regulating autophagy, apoptosis, and kidney injury in chronic kidney disease

Ying Li, Xuan Gao, Yao Chen, Huihui Li, Jing Tang, Wei Sun

07-04-2025

https://doi.org/10.4081/ejh.2025.4182

1277

PDF: 766

HTML: 51
Emodin improves renal fibrosis in chronic kidney disease by regulating mitochondrial homeostasis through the mediation of peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC-1α)

Liuchang Feng, Zaoqiang Lin, Zeyong Tang, Lin Zhu, Shu Xu, Xi Tan, Xinyuan Wang, Jianling Mai, Qinxiang Tan

13-05-2024

https://doi.org/10.4081/ejh.2024.3917

2148

PDF: 909

HTML: 54
The Qi-Bang-Yi-Shen formula ameliorates renal dysfunction and fibrosis in rats with diabetic kidney disease via regulating PI3K/AKT, ERK and PPARγ signaling pathways

Zhi Wang, Guihua Jian, Teng Chen, Yiping Chen, Junhui Li, Niansong Wang

01-03-2023

https://doi.org/10.4081/ejh.2023.3648

5047

PDF: 1180

HTML: 47
Receptor-mediated endocytosis of lysozyme in renal proximal tubules of the frog Rana temporaria

E.V. Seliverstova, N.P. Prutskova

13-04-2015

https://doi.org/10.4081/ejh.2015.2482

2576

PDF: 863

HTML: 1138
Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function

Zhijiang Chen, Huili Wang, Bin Hu, Xinxin Chen, Meiyu Zheng, Lili Liang, Juanjuan Lyu, Qiyi Zeng

21-06-2022

https://doi.org/10.4081/ejh.2022.3412

2633

PDF: 1490

HTML: 36
Developmental immunolocalization of the Klotho protein in mouse kidney epithelial cells

J.H. Song, M.Y. Lee, Y.J. Kim, S.R. Park, J. Kim, S.Y. Ryu, J.Y. Jung

24-01-2014

https://doi.org/10.4081/ejh.2014.2256

3835

PDF: 976

HTML: 513
Quantitative evaluation of CART-containing cells in urinary bladder of rats with renovascular hypertension

I. Janiuk, I. Kasacka

13-04-2015

https://doi.org/10.4081/ejh.2015.2446

2231

PDF: 702

HTML: 403
Fluorescent characterization of amyloid deposits in the kidneys of mdx mice

Valeriia Gusel'nikova, Olga Antimonova, Elena Fedorova, Mikhail Shavlovsky, Aleksandr Krutikov, Ekaterina Mikhailova, Aleksandra Gudkova, Vyacheslav Mikhailov, Dmitry Korzhevskii

03-04-2018

https://doi.org/10.4081/ejh.2018.2870

2278

PDF: 923

HTML: 46
Subcellular localization and distribution of the reduced folate carrier in normal rat tissues

M. Hinken, S. Halwachs, C. Kneuer, W. Honscha

e3

27-01-2011

https://doi.org/10.4081/ejh.2011.e3

1969

PDF: 759

HTML: 5832
Resveratrol mediates mitochondrial function through the sirtuin 3 pathway to improve abnormal metabolic remodeling in atrial fibrillation

Yuejuan Cao, Li Cui, Shaoyong Tuo, Hongze Liu, Shaonan Cui

24-04-2024

https://doi.org/10.4081/ejh.2024.4004

2128

PDF: 652

HTML: 28
Histopathological and immunofluorescent characterization of post-sepsis immune dysregulation in a clinically relevant mouse model

Haoran Tang, Chen Liao, Ning Tang, Hui Li, Yi Liu, Lingling Wang, Zongfang Ren

12-02-2026

https://doi.org/10.4081/ejh.2026.4435

684

PDF: 417

HTML: 18
circRNA-79530 regulates Twist-mediated mitochondrial damage via sponging miR-214 affecting hypoxia/reoxygenation-induced injury in H9c2 cardiomyocytes

Ziyang Yu, Wenbo Xu, Yirong Teng, Tingting Li, Ren Guo, Ju Li, Xichen Li, Yanping Li, Yinglu Hao

22-08-2025

https://doi.org/10.4081/ejh.2025.4230

440

PDF: 365

HTML: 12
Histochemical characterization of TDAG51 in endothelial remodeling and angiogenesis following myocardial infarction via PI3K-AKT signaling

Kaizheng Liu, Jinyu Pan, Quan Liu, Yang Huang, Liqun Shang, Yi Zhang, Jinming Wen, Huayang Li, Zhongkai Wu

15-06-2026

https://doi.org/10.4081/ejh.2026.4569

197

PDF: 173

HTML: 7
Expression of Ser729 phosphorylated PKCepsilon in experimental crescentic glomerulonephritis: an immunohistochemical study

V.N. Karavana, H. Gakiopoulou, E.A. Lianos

15-04-2014

https://doi.org/10.4081/ejh.2014.2308

2264

PDF: 979

HTML: 650
Ion channels alterations in the forebrain of high-fat diet fed rats

Proshanta Roy, Ilenia Martinelli, Michele Moruzzi, Federica Maggi, Consuelo Amantini, Maria Vittoria Micioni Di Bonaventura, Carlo Cifani, Francesco Amenta, Seyed Khosrow Tayebati, Daniele Tomassoni

23-11-2021

https://doi.org/10.4081/ejh.2021.3305

2303

PDF: 1190

HTML: 47
Expressions of ZNF436, β-catenin, EGFR, and CMTM5 in breast cancer and their clinical significances

Zhi Chen, Na Cui, Ji-sen Zhao, Jian-fei Wu, Fang Ma, Cong Li, Xian-yi Liu

20-01-2021

https://doi.org/10.4081/ejh.2021.3173

2422

PDF: 869

Supplementary: 208

HTML: 22
Aortic dissection is associated with reduced polycystin-1 expression, an abnormality that leads to increased ERK phosphorylation in vascular smooth muscle cells

J. Feng, S. Ge, L. Zhang, H. Che, C. Liang

16-12-2016

https://doi.org/10.4081/ejh.2016.2711

2697

PDF: 1178

HTML: 315
Colchicine alleviates severe acute pancreatitis in rats by inhibiting acinar cell ferroptosis via LCN2/MAPK/ERK signaling axis

Liu Yang, Xiaoyi Zheng, Yang Zhang, Yue Li, Lei Li, Feng Liu

11-05-2026

https://doi.org/10.4081/ejh.2026.4557

455

PDF: 643

Supplementary: 50

HTML: 8
Therapeutic effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles on ovarian functions through the PI3K/Akt cascade in mice with premature ovarian failure

Nan Li, Xue Fan, Lihong Liu, Yanbing Liu

27-07-2023

https://doi.org/10.4081/ejh.2023.3506

1909

PDF: 1162

HTML: 27
Effects of cadmium on the glial architecture in lizard brain

Rossana Favorito, Antonio Monaco, Maria C. Grimaldi, Ida Ferrandino

23-01-2017

https://doi.org/10.4081/ejh.2017.2734

3145

PDF: 844

HTML: 374
Nuclear factor-kB and nitric oxide synthases in red blood cells: good or bad in obesity? A preliminary study

Monika Široká, Caterina Franco, Zuzana Guľašová, Zdenka Hertelyová, Vladimíra Tomečková, Luigi F. Rodella, Rita Rezzani

21-01-2020

https://doi.org/10.4081/ejh.2020.3081

1851

PDF: 893

HTML: 24
Characterization of PD-1/PD-L1 immune checkpoint expression in soft tissue sarcomas

Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Masao Akagi

02-07-2021

https://doi.org/10.4081/ejh.2021.3203

3247

PDF: 1002

HTML: 39
Histochemistry in biology and medicine: a message from the citing journals

Carlo Pellicciari

23-12-2015

https://doi.org/10.4081/ejh.2015.2610

3276

PDF: 915

HTML: 901
An emerging potential therapeutic target for osteoporosis: LncRNA H19/miR-29a-3p axis

Ziqi Li, Zhinan Hong, Yuesheng Zheng, Yongwei Dong, Wei He, Yingjia Yuan, Junbiao Guo

06-11-2020

https://doi.org/10.4081/ejh.2020.3155

1642

PDF: 791

HTML: 15
Downregulation of S100 calcium-binding A4 (S100A4) ameliorates hepatic fibrosis via regulating Wnt/β-catenin signaling pathway

Chixian Zhang, Kai Bai, Dexu Li

14-04-2025

https://doi.org/10.4081/ejh.2025.4186

1458

PDF: 535

HTML: 35
SRSF3 promotes the generation of XBP1s to stabilize autophagy and enhance hypoxia adaptation in glioma

Bohu Liu, Xiaoran Zhang, Jintao Tian, Xiaobin Huang, Xuhui Li, Jinxi Zhao, Zhenghu Xu, Jun Pu

03-03-2026

https://doi.org/10.4081/ejh.2026.4530

585

PDF: 481

HTML: 13
miR-199a-5p inhibited HIF-1α to suppress the proliferation, migration, and differentiation of cardiac stem cells

Sha Li, Cuigai Zhang, Yanping Liu, Cuiqiao Meng, Yang Xie, Shuren Li

22-09-2025

https://doi.org/10.4081/ejh.2025.4239

592

PDF: 445

Supplementary: 75

HTML: 24
The expression of Sirtuins 1 and 4 in peripheral blood leukocytes from patients with type 2 diabetes

R. Song, W. Xu, Y. Chen, Z. Li, Y. Zeng, Y. Fu

e10

21-03-2011

https://doi.org/10.4081/ejh.2011.e10

2146

PDF: 702

HTML: 981
Reliable hexokinase 3 protein detection in human cell lines and primary tissue

Yasmeen H. Mady, Carmen G. Kalbermatter, Maarij Khan, Anna M. Schläfli, Rina Mehmeti, Inti Zlobec, Lucine Christe, Mario P. Tschan

12-03-2025

https://doi.org/10.4081/ejh.2025.4175

2024

PDF: 511

Supplementary: 74

Uncropped Western blots: 74

HTML: 20
Immunopositivity for Siglec-15 in gastric cancer and its association with clinical and pathological parameters

Michael Williams Leal Quirino, Michelly Cristiny Pereira, Maria de Fátima Deodato de Souza, Ivan da Rocha Pitta, Antônio Felix da Silva Filho, Mario S. de Souza Albuquerque, Amanda Pinheiro de Barros Albuquerque, Mário Rino Martins, Maira Galdino da Rocha Pitta, Moacyr Jesus Barreto de Melo Rêgo

04-03-2021

https://doi.org/10.4081/ejh.2021.3174

8404

PDF: 1312

Supplementary: 244

HTML: 21
Astragalus Ⅳ ameliorates the dry eye injury in rabbit model via MUC1-ErbB1 pathway

Li Chu, Suhong Ma, Zhiwei Chen, Wenfu Cao

01-04-2021

https://doi.org/10.4081/ejh.2021.3198

1902

PDF: 1026

HTML: 28
Nrf2 as a novel diagnostic biomarker for papillary thyroid carcinoma

Zhiyang Wang, Jing Li, Ziwei Liu, Ling Yue

20-03-2023

https://doi.org/10.4081/ejh.2023.3622

1659

PDF: 880

HTML: 41
Decreased VEGFA alleviates the symptoms of LPS-induced sepsis in a mouse model by inhibiting glycolysis and thereby regulating the polarization of macrophages

Jun Lin, Liping Jiang, Kun Guo, Ning Feng

22-12-2022

https://doi.org/10.4081/ejh.2023.3528

2130

PDF: 1311

Supplementary: 155

HTML: 45
Immunohistochemical detection of putative pathogenetic factors in adhesions of infants: a pilot study

Arvis Pauliņš, Anna Junga, Māra Pilmane

10-02-2026

https://doi.org/10.4081/ejh.2026.4438

333

PDF: 466

HTML: 12
Inhibition of HMGB1 suppresses inflammation and catabolism in temporomandibular joint osteoarthritis via NF-κB signaling pathway

Yan Yan Li, Ya Ping Feng, Li Liu, Jin Ke, Xing Long

21-06-2022

https://doi.org/10.4081/ejh.2022.3357

2256

PDF: 1177

HTML: 44
pPKCÎ± mediated-HIF-1Î± activation related to the morphological modifications occurring in neonatal myocardial tissue in response to severe and mild hyperoxia

S. Zara, V. Macchi, R. De Caro, M. Rapino, A. Cataldi, A. Porzionato

e2

31-01-2012

https://doi.org/10.4081/ejh.2012.e2

1831

PDF: 2500

HTML: 2611
VEGF promotes diabetic retinopathy by upregulating the PKC/ET/NF-κB/ICAM-1 signaling pathway

Meiying Zhang, Min Zhou, Xia Cai, Yan Zhou, Xueling Jiang, Yan Luo, Yue Hu, Rong Qiu, Yanrong Wu, Yuejin Zhang, Yan Xiong

27-10-2022

https://doi.org/10.4081/ejh.2022.3522

2612

PDF: 1093

HTML: 49
Radioprotective potential of histamine on rat small intestine and uterus

E. Carabajal, N. Massari, M. Croci, D. J. Martinel Lamas, J. P. Prestifilippo, R. M. Bergoc, E. S. Rivera, V. A. Medina

e48

18-12-2012

https://doi.org/10.4081/ejh.2012.e48

1446

PDF: 786

HTML: 914
Changes in muscularis propria of anterior vaginal wall in women with pelvic organ prolapse

A. Vetuschi, A. D'Alfonso, R. Sferra, D. Zanelli, S. Pompili, F. Patacchiola, E. Gaudio, G. Carta

16-02-2016

https://doi.org/10.4081/ejh.2016.2604

2428

PDF: 992

HTML: 635
Increased expression of STAT3 and SOCS3 in placenta from hyperglycemic rats

Vanessa Dela Justina, Sebastian San Martin, Daniela López-Espíndola, Alecsander F. M. Bressan, Raiany Alves de Freitas, Ana Maria Lopes de Passos, Juan Varas, Victor V. Lima, Fernanda R. Giachini

30-10-2019

https://doi.org/10.4081/ejh.2019.3054

1344

PDF: 881

HTML: 36
Calcium-induced alteration of mitochondrial morphology and mitochondrial-endoplasmic reticulum contacts in rat brown adipocytes

I. Golic, K. Velickovic, M. Markelic, A. Stancic, A. Jankovic, M. Vucetic, V. Otasevic, B. Buzadzic, B. Korac, A. Korac

09-09-2014

https://doi.org/10.4081/ejh.2014.2377

3503

PDF: 1238

HTML: 1551
Senescence-associated ß-galactosidase staining over the lifespan differs in a short- and a long-lived fish species

Simon Schöfer, Sylvia Laffer, Stefanie Kirchberger, Michael Kothmayer, Renate Löhnert, Elmar E. Ebner, Klara Weipoltshammer, Martin Distel, Oliver Pusch, Christian Schöfer

29-02-2024

https://doi.org/10.4081/ejh.2024.3977

2343

PDF: 1292

Supplementary: 123

HTML: 230
Immunolocalization of endocan during the endothelial-mesenchymal transition process

L. M. Carrillo, E. Arciniegas, H. R. Rojas, R. E. Ramirez

e13

01-06-2011

https://doi.org/10.4081/ejh.2011.e13

1485

PDF: 603

HTML: 1395

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